Patents Assigned to JIANGNAN UNIVERSITY
  • Patent number: 11903401
    Abstract: A method for increasing the yield of Amadori rearrangement products (ARP) based on a mechanism in which addition of tea polyphenols to deoxyosones inhibits degradation of the ARP. The method includes the following steps: dissolving and mixing amino acid, sugar and tea polyphenol in water, and adjusting a pH value; placing the obtained mixed solution in a reaction flask, and heating the mixed solution at a constant temperature in a water bath to obtain a reaction solution; and performing vacuum decompression dehydration reaction at a constant temperature; after the reaction is completed, using an ice bath to terminate the reaction to obtain a solid reactant, and redissolving the solid reactant in water to obtain an ARP solution. This method promotes the formation of ARP and inhibits degradation of ARP, so that ARP is accumulated and enriched in a large amount (80% and above yield).
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: February 20, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Xiaoming Zhang, Junhe Yu, Heping Cui, Huan Zhan, Yun Zhai, Jingyang Yu, Shuqin Xia
  • Patent number: 11891490
    Abstract: Disclosed are a protective starch-based film and its preparation method and application, belonging to the field of food packaging. According to the method for preparing the protective starch-based film, surfaces of zinc oxide nanoparticles are enabled to adsorb tannic acid and iron ions under the action of metal coordination by controlling the pH to obtain metallic polyphenol network coated zinc oxide nanoparticles, dispersion of the obtained nanoparticles is added to a starch gelatinization solution, and a melanin-like precursor is simultaneously added to form mixed liquid; and by controlling the pH of the mixed solution, ?-? stacking, self-polymerization and metal coordination are induced, so that a stable protective starch-based film with a nano-reinforced interpenetrating network structure is formed.
    Type: Grant
    Filed: August 14, 2023
    Date of Patent: February 6, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Long Chen, Hao Xu, Zhengyu Jin, Ming Miao, Yaoqi Tian, Xinwen Peng, Yidong Zou, Guanxiong Chen
  • Patent number: 11879071
    Abstract: The present disclosure discloses a low-viscosity thermosetting starch adhesive for particleboards, and a preparation method therefore, belonging to the technical field of adhesive preparation. The adhesive of the present invention selects N-hydroxyethyl acrylamide or acetoxyethyl methacrylate as the crosslinking monomer, which has a low degree of crosslinking in the process of adhesive preparation to avoid the problem of increasing viscosity, but can cross-link quickly during the hot pressing process, forming a network structure, and improving the water resistance of the adhesive; and furthermore, itaconic acid is added to promote the self-crosslinking reaction of the crosslinking monomer in the hot-pressing process, thus further improving the water resistance.
    Type: Grant
    Filed: June 13, 2023
    Date of Patent: January 23, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Li Cheng, Junnan Jin, Zhengbiao Gu, Zhaofeng Li, Yan Hong, Caiming Li, Xiaofeng Ban
  • Publication number: 20240018557
    Abstract: The present disclosure provides a recombinant nucleic acid of Escherichia coli, a recombinant E. coli, a culturing method thereof, and a method for biosynthesizing L-threonine thereby, and relates to the technical field of bioengineering. The recombinant nucleic acid of E. coli of the present disclosure, including the gene encoding phosphoenolpyruvate carboxykinase (pck), the gene encoding pyruvate carboxylase (pyc) and the gene encoding threonine operon, is transformed into E. coli to obtain a recombinant E. coli LMT4 strain that takes glucose as a substrate. Using the LMT4 for fermentative production may significantly improve the L-threonine yield and glucose conversion rate, laying a foundation for the industrial production of L-threonine.
    Type: Application
    Filed: September 7, 2022
    Publication date: January 18, 2024
    Applicant: Jiangnan University
    Inventors: Zhiming RAO, Zhenqiang ZHAO, Meijuan XU, Xian ZHANG, Taowei YANG
  • Patent number: 11866538
    Abstract: The disclosure provides a polyurethane-acrylate water repellant prepared by double bonds in the side chain, and belongs to the technical field of environment-friendly polymers. The disclosure introduces the carbon-carbon double bonds into the polyurethane side chain through a carbon-carbon double bond-containing dihydroxy micromolecular chain extender having a carbon chain structure to adjust the number of double bonds on a waterborne polyurethane chain segment participating in a free radical polymerization with acrylate monomers, thereby generating a branched structure, and improving the compatibility of polyurethane and acrylate; the fastness of a fabric is increased by combining an oxime blocking structure with the fabric. The polyurethane-acrylate water repellant prepared by the disclosure is non-toxic and low in VOC, and the finished fabric has significantly improved physical and chemical properties, and good application prospects.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: January 9, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jinmei Du, Shaofei Wang, Changhai Xu, Ankang Yao, Panfei Zhou, Zengyuan Pang
  • Patent number: 11868134
    Abstract: The present invention discloses an obstacle navigation travelling device of a power line inspection robot. The present obstacle navigation travelling device of a power line inspection robot includes: a travelling device underframe; a first arm assembly mounted at one end of the travelling device underframe; a first linear driving device for driving the first arm assembly to move linearly on the one end of the travelling device underframe; a second arm assembly mounted at one end of the travelling device underframe far from the first arm assembly; a second linear driving device for driving the second arm assembly to move linearly on the one end of the travelling device underframe far from the first arm assembly; and a third arm assembly. The present invention has the beneficial effects of a large turning range and excellent balancing.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: January 9, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventor: Wenxu Yan
  • Patent number: 11857177
    Abstract: An apparatus for suturing includes an inner strut, a spiral suturing needle, a driving mechanism, a recovery mechanism, a suture-taking-up mechanism, and a suture-feeding mechanism. Grooves are distributed on periphery with respect to an axial direction of the inner strut, a path of the groove is consistent with a path of a metallic stent to be sutured, and a width of the groove matches an outer diameter of the spiral suturing needle; the spiral suturing needle is an elastic retractable structure and a length of the spiral suturing needle without deformation is longer than a length of the path of the groove, and a suturing needle tip is arranged on a head portion of the spiral suturing needle and a suture-piercing hole is arranged on a tail portion of the spiral suturing needle.
    Type: Grant
    Filed: November 16, 2022
    Date of Patent: January 2, 2024
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Junqiang Su, Honglian Cong
  • Patent number: 11845908
    Abstract: The disclosure discloses a method for preparing functional grease through segmented solid-state fermentation of mixed fungi, and belongs to the field of edible oil processing. According to the disclosure, soybeans are used as a main fermentation substrate, for the requirements for different functional nutrition, the soybeans are matched with other oil seeds, fungus segmented solid-state fermentation is used and combined with a supercritical extraction fractionation technology, so that the purposes of improving the aftertaste of soybean oils and generating different flavors are achieved, and the nutritional value of the grease is improved. The fungus segmented solid-state fermentation of the disclosure can improve the oil yield, improve the fatty acid composition of the grease, and increase the content of main flavor substances such as pyrazines, alcohols and phenols, and the sensory functions such as flavor and color of the grease more meet the requirements of consumers for innovative products.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: December 19, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Yuanfa Liu, Jinwei Li, Yinghong Zhai
  • Patent number: 11844965
    Abstract: The invention discloses a rail type anti-falling safety device including a primary bearing block, an anti-falling tongue through-groove is opened on an upper end face of the primary bearing block, an anti-falling tongue pin is provided in the through-groove, an anti-falling tongue is provided on and rotatable about the anti-falling tongue pin, the anti-falling tongue is pressed tightly against a T-shaped steel-rail surface under the action of an elastic element, the anti-falling tongue has a cam structure at the end pressed against the T-shaped steel rail surface and a hanging loop at the end far from the end pressed against the T-shaped steel rail surface. A first clamping block is provided on a lower end face of the primary bearing block. The invention allows adjustments to the groove width of the anti-falling device while the safety and reliability is ensured, thereby providing uninterrupted personal safety guarantee for the worker.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: December 19, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventor: Wenxu Yan
  • Patent number: 11845781
    Abstract: The present disclosure discloses a preparation method and use of a double-target fusion protein, and belongs to the technical field of medicines. According to the present disclosure, a novel fusion protein is obtained by transforming an FGF19 sequence and fusing the FGF19 sequence with GLP-1. Compared with wild-type FGF19 and GLP-1, the novel fusion protein has a more long-acting and stable effect, further reduces the carcinogenic risk of FGF19, and can better relieve liver damage and correct metabolic disorder, obesity, overweight, metabolic syndrome, diabetes, dyslipidemia and other diseases. Besides, in treatment, there are no side effects of gastrointestinal discomforts such as diet decline caused by GLP-1 treatment. Therefore, the double-target fusion protein has a wide application prospect.
    Type: Grant
    Filed: March 10, 2023
    Date of Patent: December 19, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Shenglong Zhu, Yongquan Chen, Zhen Wang
  • Patent number: 11840584
    Abstract: The present disclosure discloses a simple preparation method of green acid-modified cyclodextrin, belonging to the field of cyclodextrin modification. Cyclodextrin and succinic acid are mutually modified by an esterification reaction in the presence of catalyst, and acid-modified cyclodextrin with different modification degrees is obtained by controlling reaction time at a high temperature or under a microwave action. The prepared modified cyclodextrin does not involve the use of toxic and harmful reagents, the modification reaction is simple, green and controllable, and the loading capacity of the modified cyclodextrin to guest molecules is remarkably improved compared with the loading capacity of the original cyclodextrin, so that the modified cyclodextrin has great application potential in the health fields such as food, medicines, and cosmetics.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: December 12, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Chao Qiu, Jinpeng Wang, Yao Hu, Zhengyu Jin, Qianzhu Lin, Yaoqi Tian, Aiquan Jiao, Long Chen, Zhengjun Xie, Xing Zhou
  • Patent number: 11834591
    Abstract: The present disclosure discloses a thermosetting starch adhesive for a wood-based panel and a preparation method therefor, and belongs to the technical field of preparation of adhesives. In the present disclosure, starch is used as a main raw material, and after acid hydrolysis thereof, a semi-continuous seed emulsion polymerization method is adopted to improve control of monomer polymerization stability. After grafting is completed, a cross-linking monomer with polymerizable double bonds and condensable methylol functional groups is added for copolymerization. The cross-linking monomer is also added in a semi-continuous manner. After the cross-linking reaction is completed, the reaction mixture is gelatinized and incubated, and finally a thermosetting adhesive which can be used for bonding of hot-pressed wood-based panels is obtained.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: December 5, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Li Cheng, Zhengbiao Gu, Yong Gu, Zhaofeng Li, Yan Hong, Caiming Li
  • Patent number: 11834778
    Abstract: A multifunctional high-strength composite fabric coating agent, a coating, a method for preparing the same and an application thereof are provided. The fabric coating agent includes a resin, a reinforcing agent with a reactive group, a bifunctional dispersing agent, a leveling agent, a film forming agent, a softening agent, an antibacterial agent, a solvent, and the like. The reinforcing agent is modified such that it has active functional groups of —OH and NH3. The fabric coating agent is not only easy to apply, fast to react and stabilize, but also suitable for a fabric surface of any material. A treated fabric has high tensile-breaking strength, excellent tearing and bursting performance, good waterproof-and-moisture-permeability and antibacterial performance, and high adhesion. It can be repeatedly knife coated, roll coated, calendared, or dipped. The method is not only mature in technology and low in production cost, but also suitable for large-scale application.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: December 5, 2023
    Assignee: Jiangnan University
    Inventors: Dan Zhang, Chanjuan Huang, Lei Deng, Zhu Long
  • Patent number: 11829474
    Abstract: The present invention provides a text classification backdoor attack method, system, device and a computer storage medium. The method includes: training a pretraining model by using a clean training set to obtain a clean model; generating a pseudo label data set by using a positioning label generator; performing multi-task training on a Sequence-to-Sequence model by using the pseudo label data set to obtain a locator model; generating a backdoor data set by using the locator model; and training the clean model by using the backdoor data set to obtain a dirty model. A pseudo label data set is generated by using a pretrained clean model without manual annotation. A backdoor attack location in a text sequence may be dynamically predicted by using a locator model based on a Sequence-to-Sequence and multi-task learning architecture without manual intervention, and a performance indicator obtained by dynamically selecting an attack location is better.
    Type: Grant
    Filed: July 21, 2023
    Date of Patent: November 28, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Hengyang Lu, Chenyou Fan, Wei Fang, Jun Sun, Xiaojun Wu
  • Patent number: 11828008
    Abstract: A flat-knitted three-dimensional fabric with an internal support structure, and the fabric is consisted of an upper surface layer, a lower surface layer, and a support structure yarn in a middle, wherein the upper surface layer and the lower surface layer comprise alternate-knitted single-sided stitches and fully-knitted single-sided stitches; the upper surface layer and the lower surface layer are connected by means of tuck knitting of the support structure yarn in the middle to form the integrally formed three-dimensional fabric with an internal support structure; and the alternate-knitted single-sided stitches are correspond to tuck loops formed by the support structure yarn and are used to lock the tuck loops formed by the support structure yarn in the middle, such that the support structure yarn will not puncture the surfaces of the fabric when the fabric is pressed.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: November 28, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Gaoming Jiang, Zhe Gao, Honglian Cong, Guangjun Wu, Jiangtao Tan, Mengmeng Zhou
  • Patent number: 11827878
    Abstract: The disclosure discloses construction of recombinant Saccharomyces cerevisiae for synthesizing carminic acid and application thereof and belongs to the technical field of genetic engineering and bioengineering. The disclosure obtains recombinant S. cerevisiae CA-B2 capable of synthesizing carminic acid by heterologously expressing cyclase Zhul, aromatase ZhuJ, OKS of Octaketide synthase 1, C-glucosyltransferase UGT2, monooxygenase aptC and 4?-phosphopantetheinyl transferase npgA in S. cerevisiae. The recombinant S. cerevisiae can be used for synthesizing carminic acid by taking self-synthesized acetyl-CoA and malonyl-CoA as a precursor. On this basis, OKS, cyclase, aromatase, C-glucosyltransferase and monooxygenase relevant to carminic acid are integrated to a high copy site, which can remarkably improve the yield of carminic acid. The yield of carminic acid can be increased to 2664.6 ?g/L by optimizing fermentation conditions, and the fermentation time is shortened significantly.
    Type: Grant
    Filed: August 9, 2022
    Date of Patent: November 28, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jingwen Zhou, Qian Zhang, Song Gao, Jian Chen, Weizhu Zeng, Guocheng Du
  • Patent number: 11828761
    Abstract: Disclosed is a method for detecting aflatoxin B1 based on fluorescent copper nanoparticles, belonging to the technical fields of analytical chemistry, materials science and nano biosensing. In the disclosure, ?-CD@DNA-Cu NMs are prepared by using Y-shaped DNA as a template, ascorbic acid as a reducing agent and ?-CD as a fluorescence stabilizing and enhancing agent. Then, a ratiometric fluorescent probe is constructed based on the ?-CD@DNA-Cu NMs. Finally, the detection of AFB1 with high sensitivity, high selectivity and high accuracy is achieved by using the fluorescent probe. According to the method of the disclosure, in linear ranges of 0.03-10 ppb and 10-18 ppb, a ratio value of I433 nm/I650 nm and a concentration of AFB1 exhibit a good linear relationship respectively, and a limit of detection is 0.012 ppb (S/N=3). Metal ions Ca2+ may be replaced with Yb3+, Y3+, Er3+ and Pt2+, which are also suitable for increasing sensitivity of AFB1 in rice.
    Type: Grant
    Filed: May 27, 2022
    Date of Patent: November 28, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Chifang Peng, Min Li, Shengmei Tai, Xinlin Wei
  • Patent number: 11807847
    Abstract: The invention belongs to the field of cosmetic biotechnology, and specifically relates to an Enterobacter that degrades hyaluronic acid and a cultivation method and application thereof. The Enterobacter sp. CGJ001 of the present invention was deposited in the China General Microbiological Culture Collection Center on Oct. 10, 2019, and the preservation number is CGMCC NO. 18661. The Enterobacter strain can efficiently produce hyaluronidase, and can be used in the process of preparing low molecular hyaluronic acid and oligomeric hyaluronic acid from high molecular hyaluronic acid. The enzyme has high specificity towards hyaluronic acid, excellent thermal stability and pH stability, and is suitable for large-scale industrial application. Thus, it can replace the traditional hyaluronidase extracted from expensive animal tissues. There should be broad application prospects in the fields of medicine and cosmetics.
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: November 7, 2023
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Jinsong Shi, Zhenghong Xu, Jinsong Gong, Wei Liu, Hui Li, Jianying Qian, Lei Liu, Qing Li, Mengyi Zhang, Chuanli Kang
  • Patent number: 11805578
    Abstract: The disclosure discloses a microwave processing equipment for continuous flow liquids, and belongs to the technical field of microwave processing. The microwave processing equipment includes a feed preheating section, a microwave heating section and a cooling section. The microwave heating section includes a microwave generation system, a waveguide system, tuners, and a microwave absorption cavity. The waveguide system includes at least two waveguides. Each waveguide is installed at the microwave feed port formed in the outer wall of the microwave absorption cavity according to a predetermined angle greater than or equal to 15° and less than 90°.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: October 31, 2023
    Assignees: JIANGNAN UNIVERSITY, NANJING XIANOU INSTRUMENTS MANUFACTURE CO., LTD
    Inventors: Daming Fan, Wenhua Gao, Huayu Yang, Hao Zhang, Bowen Yan, Yuhao Zhang, Jianxin Zhao, Wei Chen
  • Patent number: 11802137
    Abstract: A method for preparing an intermediate by a reduced glutathione-indicated amino acid Maillard reaction is provided. The method includes a two-stage reaction at an increased temperature. A reduced glutathione is added after different times of a low-temperature reaction, and a subsequent Maillard reaction is effectively inhibited on a basis wherein a substance is interacted with an intermediate degradation product to reduce a formation of colored substances. Comparing with a browning of Maillard products after a high-temperature stage, a reaction time with a best color inhibition effect is found to be the optimal preparation condition of the intermediate, and the intermediate is prepared in an aqueous medium at a low temperature under this optimal preparation condition. The method uses the water soluble reduced glutathione as a tracer to improve a tracing accuracy comparing to cysteine.
    Type: Grant
    Filed: July 8, 2020
    Date of Patent: October 31, 2023
    Assignees: Jiangnan University, Anhui Qiangwang Flavouring Food Co., Ltd.
    Inventors: Xiaoming Zhang, Siyun Lu, Heping Cui, Junhe Yu, Huan Zhan, Yun Zhai, Wei Tang, Jingyang Yu, Shuqin Xia