Patents Assigned to JIANGNAN UNIVERSITY
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Patent number: 11857177Abstract: An apparatus for suturing includes an inner strut, a spiral suturing needle, a driving mechanism, a recovery mechanism, a suture-taking-up mechanism, and a suture-feeding mechanism. Grooves are distributed on periphery with respect to an axial direction of the inner strut, a path of the groove is consistent with a path of a metallic stent to be sutured, and a width of the groove matches an outer diameter of the spiral suturing needle; the spiral suturing needle is an elastic retractable structure and a length of the spiral suturing needle without deformation is longer than a length of the path of the groove, and a suturing needle tip is arranged on a head portion of the spiral suturing needle and a suture-piercing hole is arranged on a tail portion of the spiral suturing needle.Type: GrantFiled: November 16, 2022Date of Patent: January 2, 2024Assignee: JIANGNAN UNIVERSITYInventors: Junqiang Su, Honglian Cong
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Patent number: 11845908Abstract: The disclosure discloses a method for preparing functional grease through segmented solid-state fermentation of mixed fungi, and belongs to the field of edible oil processing. According to the disclosure, soybeans are used as a main fermentation substrate, for the requirements for different functional nutrition, the soybeans are matched with other oil seeds, fungus segmented solid-state fermentation is used and combined with a supercritical extraction fractionation technology, so that the purposes of improving the aftertaste of soybean oils and generating different flavors are achieved, and the nutritional value of the grease is improved. The fungus segmented solid-state fermentation of the disclosure can improve the oil yield, improve the fatty acid composition of the grease, and increase the content of main flavor substances such as pyrazines, alcohols and phenols, and the sensory functions such as flavor and color of the grease more meet the requirements of consumers for innovative products.Type: GrantFiled: June 30, 2020Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventors: Yuanfa Liu, Jinwei Li, Yinghong Zhai
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Patent number: 11845781Abstract: The present disclosure discloses a preparation method and use of a double-target fusion protein, and belongs to the technical field of medicines. According to the present disclosure, a novel fusion protein is obtained by transforming an FGF19 sequence and fusing the FGF19 sequence with GLP-1. Compared with wild-type FGF19 and GLP-1, the novel fusion protein has a more long-acting and stable effect, further reduces the carcinogenic risk of FGF19, and can better relieve liver damage and correct metabolic disorder, obesity, overweight, metabolic syndrome, diabetes, dyslipidemia and other diseases. Besides, in treatment, there are no side effects of gastrointestinal discomforts such as diet decline caused by GLP-1 treatment. Therefore, the double-target fusion protein has a wide application prospect.Type: GrantFiled: March 10, 2023Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventors: Shenglong Zhu, Yongquan Chen, Zhen Wang
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Patent number: 11844965Abstract: The invention discloses a rail type anti-falling safety device including a primary bearing block, an anti-falling tongue through-groove is opened on an upper end face of the primary bearing block, an anti-falling tongue pin is provided in the through-groove, an anti-falling tongue is provided on and rotatable about the anti-falling tongue pin, the anti-falling tongue is pressed tightly against a T-shaped steel-rail surface under the action of an elastic element, the anti-falling tongue has a cam structure at the end pressed against the T-shaped steel rail surface and a hanging loop at the end far from the end pressed against the T-shaped steel rail surface. A first clamping block is provided on a lower end face of the primary bearing block. The invention allows adjustments to the groove width of the anti-falling device while the safety and reliability is ensured, thereby providing uninterrupted personal safety guarantee for the worker.Type: GrantFiled: March 18, 2019Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventor: Wenxu Yan
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Patent number: 11840584Abstract: The present disclosure discloses a simple preparation method of green acid-modified cyclodextrin, belonging to the field of cyclodextrin modification. Cyclodextrin and succinic acid are mutually modified by an esterification reaction in the presence of catalyst, and acid-modified cyclodextrin with different modification degrees is obtained by controlling reaction time at a high temperature or under a microwave action. The prepared modified cyclodextrin does not involve the use of toxic and harmful reagents, the modification reaction is simple, green and controllable, and the loading capacity of the modified cyclodextrin to guest molecules is remarkably improved compared with the loading capacity of the original cyclodextrin, so that the modified cyclodextrin has great application potential in the health fields such as food, medicines, and cosmetics.Type: GrantFiled: March 16, 2023Date of Patent: December 12, 2023Assignee: JIANGNAN UNIVERSITYInventors: Chao Qiu, Jinpeng Wang, Yao Hu, Zhengyu Jin, Qianzhu Lin, Yaoqi Tian, Aiquan Jiao, Long Chen, Zhengjun Xie, Xing Zhou
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Patent number: 11834591Abstract: The present disclosure discloses a thermosetting starch adhesive for a wood-based panel and a preparation method therefor, and belongs to the technical field of preparation of adhesives. In the present disclosure, starch is used as a main raw material, and after acid hydrolysis thereof, a semi-continuous seed emulsion polymerization method is adopted to improve control of monomer polymerization stability. After grafting is completed, a cross-linking monomer with polymerizable double bonds and condensable methylol functional groups is added for copolymerization. The cross-linking monomer is also added in a semi-continuous manner. After the cross-linking reaction is completed, the reaction mixture is gelatinized and incubated, and finally a thermosetting adhesive which can be used for bonding of hot-pressed wood-based panels is obtained.Type: GrantFiled: April 16, 2020Date of Patent: December 5, 2023Assignee: JIANGNAN UNIVERSITYInventors: Li Cheng, Zhengbiao Gu, Yong Gu, Zhaofeng Li, Yan Hong, Caiming Li
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Patent number: 11834778Abstract: A multifunctional high-strength composite fabric coating agent, a coating, a method for preparing the same and an application thereof are provided. The fabric coating agent includes a resin, a reinforcing agent with a reactive group, a bifunctional dispersing agent, a leveling agent, a film forming agent, a softening agent, an antibacterial agent, a solvent, and the like. The reinforcing agent is modified such that it has active functional groups of —OH and NH3. The fabric coating agent is not only easy to apply, fast to react and stabilize, but also suitable for a fabric surface of any material. A treated fabric has high tensile-breaking strength, excellent tearing and bursting performance, good waterproof-and-moisture-permeability and antibacterial performance, and high adhesion. It can be repeatedly knife coated, roll coated, calendared, or dipped. The method is not only mature in technology and low in production cost, but also suitable for large-scale application.Type: GrantFiled: April 17, 2018Date of Patent: December 5, 2023Assignee: Jiangnan UniversityInventors: Dan Zhang, Chanjuan Huang, Lei Deng, Zhu Long
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Patent number: 11828761Abstract: Disclosed is a method for detecting aflatoxin B1 based on fluorescent copper nanoparticles, belonging to the technical fields of analytical chemistry, materials science and nano biosensing. In the disclosure, ?-CD@DNA-Cu NMs are prepared by using Y-shaped DNA as a template, ascorbic acid as a reducing agent and ?-CD as a fluorescence stabilizing and enhancing agent. Then, a ratiometric fluorescent probe is constructed based on the ?-CD@DNA-Cu NMs. Finally, the detection of AFB1 with high sensitivity, high selectivity and high accuracy is achieved by using the fluorescent probe. According to the method of the disclosure, in linear ranges of 0.03-10 ppb and 10-18 ppb, a ratio value of I433 nm/I650 nm and a concentration of AFB1 exhibit a good linear relationship respectively, and a limit of detection is 0.012 ppb (S/N=3). Metal ions Ca2+ may be replaced with Yb3+, Y3+, Er3+ and Pt2+, which are also suitable for increasing sensitivity of AFB1 in rice.Type: GrantFiled: May 27, 2022Date of Patent: November 28, 2023Assignee: JIANGNAN UNIVERSITYInventors: Chifang Peng, Min Li, Shengmei Tai, Xinlin Wei
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Patent number: 11829474Abstract: The present invention provides a text classification backdoor attack method, system, device and a computer storage medium. The method includes: training a pretraining model by using a clean training set to obtain a clean model; generating a pseudo label data set by using a positioning label generator; performing multi-task training on a Sequence-to-Sequence model by using the pseudo label data set to obtain a locator model; generating a backdoor data set by using the locator model; and training the clean model by using the backdoor data set to obtain a dirty model. A pseudo label data set is generated by using a pretrained clean model without manual annotation. A backdoor attack location in a text sequence may be dynamically predicted by using a locator model based on a Sequence-to-Sequence and multi-task learning architecture without manual intervention, and a performance indicator obtained by dynamically selecting an attack location is better.Type: GrantFiled: July 21, 2023Date of Patent: November 28, 2023Assignee: JIANGNAN UNIVERSITYInventors: Hengyang Lu, Chenyou Fan, Wei Fang, Jun Sun, Xiaojun Wu
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Flat-knitted three-dimensional fabric with internal support structure, and method for preparing same
Patent number: 11828008Abstract: A flat-knitted three-dimensional fabric with an internal support structure, and the fabric is consisted of an upper surface layer, a lower surface layer, and a support structure yarn in a middle, wherein the upper surface layer and the lower surface layer comprise alternate-knitted single-sided stitches and fully-knitted single-sided stitches; the upper surface layer and the lower surface layer are connected by means of tuck knitting of the support structure yarn in the middle to form the integrally formed three-dimensional fabric with an internal support structure; and the alternate-knitted single-sided stitches are correspond to tuck loops formed by the support structure yarn and are used to lock the tuck loops formed by the support structure yarn in the middle, such that the support structure yarn will not puncture the surfaces of the fabric when the fabric is pressed.Type: GrantFiled: April 22, 2021Date of Patent: November 28, 2023Assignee: JIANGNAN UNIVERSITYInventors: Gaoming Jiang, Zhe Gao, Honglian Cong, Guangjun Wu, Jiangtao Tan, Mengmeng Zhou -
Patent number: 11827878Abstract: The disclosure discloses construction of recombinant Saccharomyces cerevisiae for synthesizing carminic acid and application thereof and belongs to the technical field of genetic engineering and bioengineering. The disclosure obtains recombinant S. cerevisiae CA-B2 capable of synthesizing carminic acid by heterologously expressing cyclase Zhul, aromatase ZhuJ, OKS of Octaketide synthase 1, C-glucosyltransferase UGT2, monooxygenase aptC and 4?-phosphopantetheinyl transferase npgA in S. cerevisiae. The recombinant S. cerevisiae can be used for synthesizing carminic acid by taking self-synthesized acetyl-CoA and malonyl-CoA as a precursor. On this basis, OKS, cyclase, aromatase, C-glucosyltransferase and monooxygenase relevant to carminic acid are integrated to a high copy site, which can remarkably improve the yield of carminic acid. The yield of carminic acid can be increased to 2664.6 ?g/L by optimizing fermentation conditions, and the fermentation time is shortened significantly.Type: GrantFiled: August 9, 2022Date of Patent: November 28, 2023Assignee: JIANGNAN UNIVERSITYInventors: Jingwen Zhou, Qian Zhang, Song Gao, Jian Chen, Weizhu Zeng, Guocheng Du
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Patent number: 11807847Abstract: The invention belongs to the field of cosmetic biotechnology, and specifically relates to an Enterobacter that degrades hyaluronic acid and a cultivation method and application thereof. The Enterobacter sp. CGJ001 of the present invention was deposited in the China General Microbiological Culture Collection Center on Oct. 10, 2019, and the preservation number is CGMCC NO. 18661. The Enterobacter strain can efficiently produce hyaluronidase, and can be used in the process of preparing low molecular hyaluronic acid and oligomeric hyaluronic acid from high molecular hyaluronic acid. The enzyme has high specificity towards hyaluronic acid, excellent thermal stability and pH stability, and is suitable for large-scale industrial application. Thus, it can replace the traditional hyaluronidase extracted from expensive animal tissues. There should be broad application prospects in the fields of medicine and cosmetics.Type: GrantFiled: August 8, 2022Date of Patent: November 7, 2023Assignee: JIANGNAN UNIVERSITYInventors: Jinsong Shi, Zhenghong Xu, Jinsong Gong, Wei Liu, Hui Li, Jianying Qian, Lei Liu, Qing Li, Mengyi Zhang, Chuanli Kang
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Patent number: 11802167Abstract: A method for producing a cold-water-soluble starch. The method includes: 1) adding a starch and 3-45 wt. % of an ethanol aqueous solution to a container, and stirring a mixture of the starch and the ethanol aqueous solution in the container, thus yielding a starch-ethanol-water; 2) introducing the starch-ethanol-water to an extruder and producing a noodle extrudate, where the extruder comprises 3 continuous temperature control areas: a first area having a temperature of 50° C., a second area having a temperature of between 95 and 120° C., and a third area having a temperature of 60° C.; a rotation speed of the extruder is 70-150 rpm; and the noodle extrudate has a diameter of 0.2-0.5 cm; 3) pressing and roll slitting the noodle extrudate, thus yielding a plurality of slices; and 4) drying the plurality of slices in a microwave vacuum oven, cooling, and pulverizing the plurality of slices.Type: GrantFiled: November 13, 2020Date of Patent: October 31, 2023Assignee: JIANGNAN UNIVERSITYInventors: Xing Zhou, Tingting Meng, Zhengyu Jin, Ren Wang, Jianwei Zhao, Jinpeng Wang, Aiquan Jiao, Xueming Xu
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Patent number: 11805578Abstract: The disclosure discloses a microwave processing equipment for continuous flow liquids, and belongs to the technical field of microwave processing. The microwave processing equipment includes a feed preheating section, a microwave heating section and a cooling section. The microwave heating section includes a microwave generation system, a waveguide system, tuners, and a microwave absorption cavity. The waveguide system includes at least two waveguides. Each waveguide is installed at the microwave feed port formed in the outer wall of the microwave absorption cavity according to a predetermined angle greater than or equal to 15° and less than 90°.Type: GrantFiled: August 10, 2020Date of Patent: October 31, 2023Assignees: JIANGNAN UNIVERSITY, NANJING XIANOU INSTRUMENTS MANUFACTURE CO., LTDInventors: Daming Fan, Wenhua Gao, Huayu Yang, Hao Zhang, Bowen Yan, Yuhao Zhang, Jianxin Zhao, Wei Chen
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Patent number: 11802915Abstract: An uncertain noisy filtering-based fault diagnosis method for a power battery management system is described. The method includes establishing an electro-thermal coupling model of the power battery system; extending an output vector of the system according to a state constraint of a power battery, and expanding a state vector of the system according to a fault of the power battery system to obtain an augmented system of the power battery system; obtaining an estimation interval of a power battery sensor fault by using a zonotope Kalman filtering method; judging whether the power battery management system has a fault according to upper and lower bounds of fault estimation; if a fault occurs, determining a fault type and a fault time according to a result.Type: GrantFiled: July 26, 2022Date of Patent: October 31, 2023Assignee: JIANGNAN UNIVERSITYInventors: Ziyun Wang, Yan Wang, Yacong Zhan, Zhicheng Ji, Zixing Liu, Yuqian Chen, Leiting Huo
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Patent number: 11802137Abstract: A method for preparing an intermediate by a reduced glutathione-indicated amino acid Maillard reaction is provided. The method includes a two-stage reaction at an increased temperature. A reduced glutathione is added after different times of a low-temperature reaction, and a subsequent Maillard reaction is effectively inhibited on a basis wherein a substance is interacted with an intermediate degradation product to reduce a formation of colored substances. Comparing with a browning of Maillard products after a high-temperature stage, a reaction time with a best color inhibition effect is found to be the optimal preparation condition of the intermediate, and the intermediate is prepared in an aqueous medium at a low temperature under this optimal preparation condition. The method uses the water soluble reduced glutathione as a tracer to improve a tracing accuracy comparing to cysteine.Type: GrantFiled: July 8, 2020Date of Patent: October 31, 2023Assignees: Jiangnan University, Anhui Qiangwang Flavouring Food Co., Ltd.Inventors: Xiaoming Zhang, Siyun Lu, Heping Cui, Junhe Yu, Huan Zhan, Yun Zhai, Wei Tang, Jingyang Yu, Shuqin Xia
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Patent number: 11787896Abstract: The present disclosure discloses a preparation method of an ultraviolet (UV)-resistant and transparent lignin-based polyurethane (PU) elastomer. During the synthesis process, natural lignin-based polyols are directly used as an end-capping agent, isophorone diisocyanate and 2,2-dimethylolbutyric acid are used as a hard segment and polyether chain polyols are used as a soft segment, to synthesize a PU elastomer with a transparent brown appearance, excellent high elasticity and elastic recovery performance, as well as excellent mechanical properties, excellent UV resistance and repeatable processability. The lignin-based PU elastomer has a simple preparation process, and has great potential values for use in the fields such as PU elastomer film, fabric coating, and elastic fiber and biomass polymer materials.Type: GrantFiled: July 27, 2022Date of Patent: October 17, 2023Assignee: JIANGNAN UNIVERSITYInventors: Chaoxia Wang, Xinxiang Li, Yunjie Yin
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Patent number: 11788196Abstract: The present disclosure discloses an ABO3 type high-entropy perovskite Bax(FeCoNiZrY)0.2O3-? electrocatalytic material and a preparation method thereof, belonging to the technical field of electrocatalytic materials. The electrocatalytic material is prepared by taking hydrated cobalt nitrate, hydrated ferric nitrate, hydrated nickel nitrate, barium nitrate, hydrated yttrium nitrate, hydrated zirconium nitrate and polyacrylonitrile staple fibers as raw materials through processes of liquid phase chelation, gelation, calcination, etc. The prepared high-entropy perovskite Bax(FeCoNiZrY)0.2O3-? electrocatalytic material can release more electrochemical active sites due to its special nanostructure, thus showing better electrocatalytic activity.Type: GrantFiled: March 1, 2023Date of Patent: October 17, 2023Assignee: JIANGNAN UNIVERSITYInventors: Tianxi Liu, Kaibin Chu, Feili Lai
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Patent number: 11781118Abstract: The disclosure discloses preparation of an L-amino acid deaminase mutant and application thereof, belonging to the technical field of gene engineering. Through pmirLAAD protein modification, analysis of a flexible loop structure around a binding site of the pmirLAAD product, and design of the best mutant, the modification method of the disclosure overcomes the defect that the catalytic efficiency of the previous wild-type enzyme is reduced due to product inhibition, and is tested by experiments. Compared with the control, the catalytic efficiency (1.61 mM?1·min?1) and the product inhibition constant (5.4 mM) of the finally obtained best mutant pmirLAADM4 are respectively increased by 5.2 times and 5.7 times. The yield of ?-ketoisovaleric acid can reach 96.5 g/L, and the transformation rate is greater than 97%. By adopting the method of the disclosure, the cost can be greatly reduced, and the industrialization process of production of ?-ketoisovaleric acid by an enzymatic transformation method is accelerated.Type: GrantFiled: June 18, 2021Date of Patent: October 10, 2023Assignee: Jiangnan UniversityInventors: Jing Wu, Shanshan Pei, Jia Liu, Wei Song, Xiulai Chen, Qiuling Luo
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Patent number: 11780905Abstract: The disclosure provides an active peptide with an anti-lipid oxidation function and a preparation method and application thereof and belongs to the technical field of plant-derived biologically active peptides. In the disclosure, oil processing by-products, namely oil crops after oil extraction, are used as the raw materials, and the raw materials are subjected to the steps of protein extraction, infrared pretreatment, proteolysis, freeze-drying, lipophilic part extraction, vacuum concentration and drying to prepare an anti-lipid oxidation peptide having the functional characteristics of scavenging DPPH free radicals, chelating metal ions, inhibiting lipid peroxidation, prolonging vegetable oil oxidation induction time, improving emulsion stability and the like.Type: GrantFiled: February 8, 2021Date of Patent: October 10, 2023Assignee: JIANGNAN UNIVERSITYInventors: Fei Xu, Jinyuan Hu