Patents Assigned to JIANGNAN UNIVERSITY
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Patent number: 11951450Abstract: A processing system and processing method for blocked microreactor. The processing system comprises an gas intake device, a flushing device, a microreactor to be processed and a plasma processing device. One end of the microreactor to be processed is connected with the gas intake device and the flushing device through a pipeline; the other end of the microreactor to be processed is connected with a waste liquid bottle through the pipeline; and the microreactor to be processed is arranged between electrodes of the plasma processing device. The present invention uses the effective reactivity of plasma and active free radicals in an excitation atmosphere to crack micro blockage in a micro channel in a short time. The method of the present invention has high flexibility and strong controllability, and can select plasma electrodes according to blocked regions to crack the blockage in a specific region.Type: GrantFiled: October 31, 2022Date of Patent: April 9, 2024Assignee: JIANGNAN UNIVERSITYInventors: Liangliang Lin, Ziyi Zhang, Lichen Rui
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Patent number: 11946088Abstract: The disclosure discloses a method for processing oil crops with rhodotorula, and belongs to the technical field of fermentation. The method includes the step of inoculating the rhodotorula (such as Rhodotorula mucilaginosa, Sporidiobolus salmonicolor and Rhodotorula glutinis) that can produce carotenoid into a fermentation medium that contains oil-rich oil crops for solid state fermentation to obtain oil and oil crop meal rich in carotenoid. The carotenoid as a fermentative metabolite of the rhodotorula has bioactivities of resisting oxidation, preventing vascular sclerosis, enhancing immunity and preventing cancers. Contents of carotenoid in the oil and oil crop meal acquired by the method can be up to 9.071 ?g/g and 8.062 ?g/g correspondingly.Type: GrantFiled: June 18, 2021Date of Patent: April 2, 2024Assignee: JIANGNAN UNIVERSITYInventors: Yuanfa Liu, Zhongyang Ding, Yunzhi Jiang, Liting Zhao, Mengmeng Xu, Qi Zhang, Zhenghua Gu, Guiyang Shi
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Patent number: 11946197Abstract: The present disclosure relates to a method for modifying polyester by a swelling agent combined with cutinase, belonging to the technical field of textile processing. According to the method, a phenol solution or an o-vanillin solution is used as the swelling agent to perform swelling treatment on the polyester, and combined with a Humicola insolens cutinase solution to perform hydrophilic modification on the polyester, which not only significantly improves the release amount of hydrolysates, but also reduces the fabric mass loss compared with the traditional chemical modification method.Type: GrantFiled: July 27, 2023Date of Patent: April 2, 2024Assignee: JIANGNAN UNIVERSITYInventors: Jiajia Fu, Jundan Feng, Artur Cavaco-paulo, Rong Li, Yuzheng Lu, Xinming Zheng, Ruijuan Han, Chaoran Meng
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Patent number: 11946196Abstract: The present disclosure discloses an atmospheric-pressure plasma equipment for fabric functional finishing and its application, and belongs to the field of textile printing and dyeing engineering. The atmospheric-pressure plasma equipment, including a discharging system, a grafting instrument and a cloth guider, can conduct continuous plasma treatment on fabrics under an atmospheric pressure, including plasma etching and plasma grafting, which breaks through the disadvantage of batch processing of vacuum plasma equipment. The equipment and method of the present disclosure realize functional finishing of the fabrics in the absence of water, and this finishing process is cost efficient, environmentally friendly, uniform, shorter treatment time and higher reactivity, and applicable to many materials and can keep the bulk properties of the treated substances.Type: GrantFiled: March 29, 2021Date of Patent: April 2, 2024Assignee: JIANGNAN UNIVERSITYInventors: Chang-E Zhou, Hongwei Wang, Wenkai Shen, Lei Fan, Xin Ju, Guozheng Zhang, Tongxin Yang, Wanning Wang, Chang Sun
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Patent number: 11938629Abstract: A micro-robot magnetic drive device and a control method based on double closed loop three-dimensional path tracking are disclosed. The method includes: inputting a desired tracking path, obtaining current pose information of a magnetic micro-robot through a camera, and then calculating a position of a center of mass, an actual axial direction, coordinates of a desired position point with the shortest distance from the center of mass on a desired tracking path, and a tangent direction of this point; calculating a horizontal distance, a vertical distance, a direction angle error, and a pitch angle error of the two points according to the actual axial direction, the tangent direction, and disturbance compensation; and obtaining a required rotating magnetic field according to a designed position closed loop controller.Type: GrantFiled: November 9, 2021Date of Patent: March 26, 2024Assignee: JIANGNAN UNIVERSITYInventors: Qigao Fan, Wei Chen, Linbai Xie, Yixin Zhu, Guofeng Yang, Yueyang Li, Kaitao Bi, Wentao Huang, Haichi Luo, Zhengqing Zhao
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Patent number: 11938465Abstract: The invention discloses a coordination type zirconium phosphotungstate catalyst and its application in catalytic hydrogenation of furfural, belonging to the field of heterogeneous catalysis. The zirconium phosphotungstate catalyst prepared by the invention not only has good catalytic effect on the conversion of furfural to furfuryl alcohol, but also has mild reaction conditions. The yield of solid line furfuryl alcohol can be 98% if it can be reacted for 1 h at 120 ° C., and the amount of catalyst is less, which greatly reduces the energy consumption in the prior art. In addition, the zirconium phosphotungstate prepared by the invention is easy to separate, has good stability for catalyzing the hydrogenation of furfural to furfuryl alcohol, and is a new, efficient and green catalyst.Type: GrantFiled: March 18, 2019Date of Patent: March 26, 2024Assignee: JIANGNAN UNIVERSITYInventors: Liping Zhang, Haijun Wang, Guangzhi Xu, Chen Liu
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Patent number: 11925708Abstract: The invention provides a making method of modified polyvinyl alcohol embolic microspheres. First, polyvinyl alcohol dimethyl sulfoxide solution is added to acryloyl chloride dichloromethane solution for reaction, then taurine solution is added to the above solution for further reaction, so that functional groups are introduced into the side chains of polyvinyl alcohol, then blank microspheres are prepared by suspension crosslinking method, and finally, drug-loaded modified polyvinyl alcohol embolic microspheres are prepared. The invention aims at improving the drug loading rate and drug loading speed of the microspheres. Through modification, the crystallinity of polyvinyl alcohol is weakened, the swelling in water is accelerated, and the application effect of the microspheres is improved.Type: GrantFiled: October 24, 2022Date of Patent: March 12, 2024Assignee: JIANGNAN UNIVERSITYInventors: Liping Zhang, Yi Zhu, Wenlong Wang, Caihua Ni
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Patent number: 11911353Abstract: The disclosure discloses a fatty acid synthase inhibitor and application thereof and belongs to the technical field of medical biology. The fatty acid synthase inhibitor of the disclosure can significantly inhibit the activity of fatty acid synthase without affecting normal expression, and adjust the ratio of fatty acids in cells. The fatty acid synthase inhibitor of the disclosure has a good tumor proliferation inhibitory effect, can arrest the growth cycle of tumor cells in the interphase, prevent tumor cell division, inhibit tumor cell proliferation, promote tumor cell apoptosis and exert a tumor treatment effect, can be used to treat tumors and metabolism related diseases, and has an important clinical application prospect.Type: GrantFiled: October 30, 2020Date of Patent: February 27, 2024Assignee: JIANGNAN UNIVERSITYInventors: Yongquan Chen, Hongyan Qu, Chunlei Tang, Guosheng Wu, Guozhen Cui, Ninghan Feng, Xiaoying Wang, Kai Shan, Shenglong Zhu, Lengyun Wei
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Publication number: 20240060076Abstract: The disclosure relates to a thermal switch system and application thereof in improving yield of amino acid, and particularly relates to a method for improving the yield of amino acid by regulating intracellular metabolic flux distribution using the thermal switch system, which belongs to the technical fields of genetic engineering and microbial fermentation. The system rebalances metabolic flux between pyruvate and oxaloacetate by controlling heterologous expression of pyruvate carboxylase and in combination with chemical properties that oxaloacetate is temperature-sensitive and easy to decarboxylate, and dynamically regulates a central metabolic pathway to ensure the supply of reducing cofactors, so as to promote the production of L-threonine. Temperature-controlled threonine-producing strains TWF106/pFT24rp and TWF113/pFT24rpa1 obtained in the disclosure have threonine molar conversion rates of 111.78% and 124.03% respectively.Type: ApplicationFiled: May 17, 2022Publication date: February 22, 2024Applicant: Jiangnan UniversityInventors: Xiaoyuan WANG, Yu FANG, Jianli WANG, Shuyan ZHANG, Xiaoqing HU
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Patent number: 11910536Abstract: In a direct-ink-writing (DIW) method for printing a strain gauge array circuit, several insulating strips are printed on the upper layer of the first circuit layer after the first circuit layer has been printed and cured, and the second circuit layer is then printed at the insulating strips. The functional layer of a strain gauge is printed and covered thereon without contacting the insulating strips; the head and tail electrodes of the functional layer are respectively connected to two layers of circuit layers; and finally, a layer of insulating material is printed for encapsulation. DIW is used to complete the whole printing. A new insulating method is used in a cross part of two silver lines of a row-column compound circuit. The local glue dispensing is changed to printing the insulating strips in routing regions, and ensures the strain transmission efficiency from the strain gauge substrate to the functional layer.Type: GrantFiled: March 23, 2022Date of Patent: February 20, 2024Assignee: JIANGNAN UNIVERSITYInventors: Peishi Yu, Junhua Zhao, Lixin Qi, Zhiyang Guo, Yu Liu
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Patent number: 11903401Abstract: A method for increasing the yield of Amadori rearrangement products (ARP) based on a mechanism in which addition of tea polyphenols to deoxyosones inhibits degradation of the ARP. The method includes the following steps: dissolving and mixing amino acid, sugar and tea polyphenol in water, and adjusting a pH value; placing the obtained mixed solution in a reaction flask, and heating the mixed solution at a constant temperature in a water bath to obtain a reaction solution; and performing vacuum decompression dehydration reaction at a constant temperature; after the reaction is completed, using an ice bath to terminate the reaction to obtain a solid reactant, and redissolving the solid reactant in water to obtain an ARP solution. This method promotes the formation of ARP and inhibits degradation of ARP, so that ARP is accumulated and enriched in a large amount (80% and above yield).Type: GrantFiled: April 21, 2020Date of Patent: February 20, 2024Assignee: JIANGNAN UNIVERSITYInventors: Xiaoming Zhang, Junhe Yu, Heping Cui, Huan Zhan, Yun Zhai, Jingyang Yu, Shuqin Xia
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Patent number: 11891490Abstract: Disclosed are a protective starch-based film and its preparation method and application, belonging to the field of food packaging. According to the method for preparing the protective starch-based film, surfaces of zinc oxide nanoparticles are enabled to adsorb tannic acid and iron ions under the action of metal coordination by controlling the pH to obtain metallic polyphenol network coated zinc oxide nanoparticles, dispersion of the obtained nanoparticles is added to a starch gelatinization solution, and a melanin-like precursor is simultaneously added to form mixed liquid; and by controlling the pH of the mixed solution, ?-? stacking, self-polymerization and metal coordination are induced, so that a stable protective starch-based film with a nano-reinforced interpenetrating network structure is formed.Type: GrantFiled: August 14, 2023Date of Patent: February 6, 2024Assignee: JIANGNAN UNIVERSITYInventors: Long Chen, Hao Xu, Zhengyu Jin, Ming Miao, Yaoqi Tian, Xinwen Peng, Yidong Zou, Guanxiong Chen
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Patent number: 11879071Abstract: The present disclosure discloses a low-viscosity thermosetting starch adhesive for particleboards, and a preparation method therefore, belonging to the technical field of adhesive preparation. The adhesive of the present invention selects N-hydroxyethyl acrylamide or acetoxyethyl methacrylate as the crosslinking monomer, which has a low degree of crosslinking in the process of adhesive preparation to avoid the problem of increasing viscosity, but can cross-link quickly during the hot pressing process, forming a network structure, and improving the water resistance of the adhesive; and furthermore, itaconic acid is added to promote the self-crosslinking reaction of the crosslinking monomer in the hot-pressing process, thus further improving the water resistance.Type: GrantFiled: June 13, 2023Date of Patent: January 23, 2024Assignee: JIANGNAN UNIVERSITYInventors: Li Cheng, Junnan Jin, Zhengbiao Gu, Zhaofeng Li, Yan Hong, Caiming Li, Xiaofeng Ban
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Publication number: 20240018557Abstract: The present disclosure provides a recombinant nucleic acid of Escherichia coli, a recombinant E. coli, a culturing method thereof, and a method for biosynthesizing L-threonine thereby, and relates to the technical field of bioengineering. The recombinant nucleic acid of E. coli of the present disclosure, including the gene encoding phosphoenolpyruvate carboxykinase (pck), the gene encoding pyruvate carboxylase (pyc) and the gene encoding threonine operon, is transformed into E. coli to obtain a recombinant E. coli LMT4 strain that takes glucose as a substrate. Using the LMT4 for fermentative production may significantly improve the L-threonine yield and glucose conversion rate, laying a foundation for the industrial production of L-threonine.Type: ApplicationFiled: September 7, 2022Publication date: January 18, 2024Applicant: Jiangnan UniversityInventors: Zhiming RAO, Zhenqiang ZHAO, Meijuan XU, Xian ZHANG, Taowei YANG
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Patent number: 11866538Abstract: The disclosure provides a polyurethane-acrylate water repellant prepared by double bonds in the side chain, and belongs to the technical field of environment-friendly polymers. The disclosure introduces the carbon-carbon double bonds into the polyurethane side chain through a carbon-carbon double bond-containing dihydroxy micromolecular chain extender having a carbon chain structure to adjust the number of double bonds on a waterborne polyurethane chain segment participating in a free radical polymerization with acrylate monomers, thereby generating a branched structure, and improving the compatibility of polyurethane and acrylate; the fastness of a fabric is increased by combining an oxime blocking structure with the fabric. The polyurethane-acrylate water repellant prepared by the disclosure is non-toxic and low in VOC, and the finished fabric has significantly improved physical and chemical properties, and good application prospects.Type: GrantFiled: July 24, 2020Date of Patent: January 9, 2024Assignee: JIANGNAN UNIVERSITYInventors: Jinmei Du, Shaofei Wang, Changhai Xu, Ankang Yao, Panfei Zhou, Zengyuan Pang
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Patent number: 11868134Abstract: The present invention discloses an obstacle navigation travelling device of a power line inspection robot. The present obstacle navigation travelling device of a power line inspection robot includes: a travelling device underframe; a first arm assembly mounted at one end of the travelling device underframe; a first linear driving device for driving the first arm assembly to move linearly on the one end of the travelling device underframe; a second arm assembly mounted at one end of the travelling device underframe far from the first arm assembly; a second linear driving device for driving the second arm assembly to move linearly on the one end of the travelling device underframe far from the first arm assembly; and a third arm assembly. The present invention has the beneficial effects of a large turning range and excellent balancing.Type: GrantFiled: March 18, 2019Date of Patent: January 9, 2024Assignee: JIANGNAN UNIVERSITYInventor: Wenxu Yan
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Patent number: 11857177Abstract: An apparatus for suturing includes an inner strut, a spiral suturing needle, a driving mechanism, a recovery mechanism, a suture-taking-up mechanism, and a suture-feeding mechanism. Grooves are distributed on periphery with respect to an axial direction of the inner strut, a path of the groove is consistent with a path of a metallic stent to be sutured, and a width of the groove matches an outer diameter of the spiral suturing needle; the spiral suturing needle is an elastic retractable structure and a length of the spiral suturing needle without deformation is longer than a length of the path of the groove, and a suturing needle tip is arranged on a head portion of the spiral suturing needle and a suture-piercing hole is arranged on a tail portion of the spiral suturing needle.Type: GrantFiled: November 16, 2022Date of Patent: January 2, 2024Assignee: JIANGNAN UNIVERSITYInventors: Junqiang Su, Honglian Cong
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Patent number: 11844965Abstract: The invention discloses a rail type anti-falling safety device including a primary bearing block, an anti-falling tongue through-groove is opened on an upper end face of the primary bearing block, an anti-falling tongue pin is provided in the through-groove, an anti-falling tongue is provided on and rotatable about the anti-falling tongue pin, the anti-falling tongue is pressed tightly against a T-shaped steel-rail surface under the action of an elastic element, the anti-falling tongue has a cam structure at the end pressed against the T-shaped steel rail surface and a hanging loop at the end far from the end pressed against the T-shaped steel rail surface. A first clamping block is provided on a lower end face of the primary bearing block. The invention allows adjustments to the groove width of the anti-falling device while the safety and reliability is ensured, thereby providing uninterrupted personal safety guarantee for the worker.Type: GrantFiled: March 18, 2019Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventor: Wenxu Yan
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Patent number: 11845908Abstract: The disclosure discloses a method for preparing functional grease through segmented solid-state fermentation of mixed fungi, and belongs to the field of edible oil processing. According to the disclosure, soybeans are used as a main fermentation substrate, for the requirements for different functional nutrition, the soybeans are matched with other oil seeds, fungus segmented solid-state fermentation is used and combined with a supercritical extraction fractionation technology, so that the purposes of improving the aftertaste of soybean oils and generating different flavors are achieved, and the nutritional value of the grease is improved. The fungus segmented solid-state fermentation of the disclosure can improve the oil yield, improve the fatty acid composition of the grease, and increase the content of main flavor substances such as pyrazines, alcohols and phenols, and the sensory functions such as flavor and color of the grease more meet the requirements of consumers for innovative products.Type: GrantFiled: June 30, 2020Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventors: Yuanfa Liu, Jinwei Li, Yinghong Zhai
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Patent number: 11845781Abstract: The present disclosure discloses a preparation method and use of a double-target fusion protein, and belongs to the technical field of medicines. According to the present disclosure, a novel fusion protein is obtained by transforming an FGF19 sequence and fusing the FGF19 sequence with GLP-1. Compared with wild-type FGF19 and GLP-1, the novel fusion protein has a more long-acting and stable effect, further reduces the carcinogenic risk of FGF19, and can better relieve liver damage and correct metabolic disorder, obesity, overweight, metabolic syndrome, diabetes, dyslipidemia and other diseases. Besides, in treatment, there are no side effects of gastrointestinal discomforts such as diet decline caused by GLP-1 treatment. Therefore, the double-target fusion protein has a wide application prospect.Type: GrantFiled: March 10, 2023Date of Patent: December 19, 2023Assignee: JIANGNAN UNIVERSITYInventors: Shenglong Zhu, Yongquan Chen, Zhen Wang