Abstract: Disclosed is a semiconductor integrated circuit device including a transmitting circuit and a receiving coil inductively coupled to a transmitting coil. The transmitting circuit transmits data by supplying a current through the transmitting coil not at the time of transition of data but at every rising edge or falling edge of a clock used in transmission of data. At every rising edge or falling edge of the clock, a receiving circuit captures a voltage induced in the receiving coil due to the current flowing through the transmitting coil, reproduces the transmitted data and outputs the reproduced data.

Abstract: The present invention relates to the use of non-pathogenic antibodies to deliver biologically-active proteins to specific cellular and sub-cellular sites. The invention also relates to the use of non-pathogenic antibodies to deliver biologically-active, non-protein molecules to specific cellular and sub-cellular sites.

Abstract: An electronic circuit for which a coil 22 is disposed overlapping with a memory array region to carry out communications by inductive coupling between stacked and mounted chips by the coil 22. Because intersections 1 and 2 between the coil 22 and a bit line 15 are located at a pair of positions that are equal to each other in wiring length from both terminals a and g of the coil 22, interference from the bit line 15 to the coil 22 results in the same phase and same amplitude at both ends of the coil 22, and can thus be eliminated by a differential amplifier. Thereby, a coil antenna can be disposed so that, even when a coil antenna to carry out communications by inductive coupling is disposed overlapping with a memory array region, little interference occurs from a memory array wiring to communications by the coil antenna.

Abstract: Improving channel response characteristics between a transmitter and a receiver, in a Multiple-Input-Multiple-Output (MIMO)-system without increasing the number of receiving antennas, by using fractional sampling in a receiver, delaying and transmitting part of plural transmitting signals demodulating data of the plural data series.

Abstract: An event detecting apparatus capable of high-precision detection of an event even by use of a narrow-band signal comprises: a plurality of antennas 21 that receive radio waves transmitted from a transmitter, a correlation matrix operation unit 22 that expresses signals received by the plurality of antennas 21 as received vectors, to operate a correlation matrix on the basis of the received vectors, an eigenvector operation unit 23 that performs eigenvalue expansion of the correlation matrix operated by the correlation matrix operation unit 22, to operate eigenvectors covering a signal subspace, and an event detecting unit 24 that detects a temporal change in the eigenvectors operated by the eigenvector operation unit 23, to detect an event.

Abstract: The invention features methods for inhibiting enhancement of expression of a FoxP3 gene in a cell, methods for inhibiting induction of differentiation of a cell into a regulatory T cell, methods for reducing immunosuppression, methods for stimulating tumor immunity, and methods for treating a patient with a tumor. The methods of the invention involve suppressing function of an FSTL1 protein in the cell. In the methods of the invention, function of an FSTL1 protein in the cell may be suppressed using an anti-FSTL1 antibody.

Abstract: It is to provide a novel head-and-neck tumor proliferation inhibitor, head-and-neck tumor metastasis inhibitor and pharmaceutical composition for treating a head-and-neck tumor. The present invention is characterized by using an inhibitory substance of a microRNA whose expression increases in a head-and-neck tumor and/or a promoting substance of a microRNA whose expression decreases in a head-and-neck tumor. Preferred examples of the microRNA whose expression increases in a head-and-neck tumor include miR-455-3p, miR-455-5p, miR-130b, miR-130b*, miR-801, miR-196a, miR-21 and miR-31. Preferred examples of the microRNA whose expression decreases in a head-and-neck tumor include miR-133b, miR-145 and miR-375.

Abstract: An information communication apparatus (100A) that receives transmission information transmitted from a broadcast station, generates and relays response information to an information communication apparatus (100C) having access to a communication network (120) includes: a broadcast-wave I/F that receives the transmission information; a wireless I/F that transmits the response information to the information communication apparatus (100C) capable of wireless communication to relay the response information to an area having access to the communication network (120); a communication network I/F that is connected to the communication network (120) and transmits the response information; a response-transmission-information generating unit that generates the response information; and a connection control unit that determines whether the communication network (120) is accessible, transmits the response information to the communication network (120) when accessible, and relays the response information to the connectab

Abstract: A pulse transmission technique is used for wireless communication between a microcomputer (13) having a debugging support circuit (17) and a debugger (13). The pulse transmission technique is based on magnetic field coupling between a first coil (14) provided for the microcomputer and a second coil (8) coupled with the debugger. During an initialization operation, the microcomputer performs a process of configuring a communication condition of the wireless communication to perform the wireless communication. The microcomputer awaits control from the debugger when the microcomputer establishes communication with the debugger. The debugger awaits establishment of the communication and proceeds to control of the microcomputer in accordance with the wireless communication. It is possible to provide contactless interface for system debugging without the need for a large antenna or a large-scale circuit for modulation and demodulation.

Abstract: An agent containing a vinca alkaloid or its pharmacologically acceptable salt as an active ingredient can induce insulin production and/or secretion of non-neoplastic cells derived from the pancreas.

Abstract: The object of the present invention is to provide a mouse model for allergic diseases such as atopic dermatitis, and a dermatitis mouse model with impaired skin-barrier function. The present inventors found out that a mouse that has been caused to completely lose the function of expressing profilaggrin protein and filaggrin protein by entirely or partially disrupting the endogenous gene encoding filaggrin by a genetic mutation such as deletion or replacement, can be used as a mouse model for allergic diseases or atopic dermatitis wherein the skin-barrier function has been impaired.

Abstract: The object is to enable the calculation of load transfer paths in case of distributed load applied to the structure with the numerical structure-analysis calculation system. The value of the parameter U** at each point is calculated according to the ratio of the complementary strain energy U at the application of load without fixing the point in the structure and the complementary strain energy U? at the application of load with fixing one point in the structure. In the actual calculation, according to the complementary strain energy U, and the flexibility matrix CAC with respect to the loading point A and one point C in the structure, and the inverse matrix CCC?1 of the flexibility matrix with respect to point C, and the load pA at the loading point A, the value of the parameter U** (CACCCC?1CCApA·pA/(2U)) at point C is calculated.

Abstract: An object of the present invention is to provide methods for diagnosing and/or treating tumors using HERV-H env gene or HERV-H env Env protein. Specifically, tumors are diagnosed by detecting expression of HERV-H env gene; and agents for detecting the expression are used as diagnosing agents. Further, tumors are treated by inhibiting function of HERV-H env gene; and agents for inhibiting the function are used as antitumor agents. Furthermore, tumors are treated by administering a peptide having a certain sequence of HERV-H Env protein and the like; and the peptide is used as a cancer vaccine.

Abstract: A technology is disclosed for easily executing a compositional analysis to obtain a preferred composition. Image data is acquired, the image data is analyzed, and a plurality of composition lines expressing the feature of the image data on the composition are acquired. On the composition formed of the plurality of acquired composition lines, the ratio of lengths of two sides selected from the plurality of sides in the region partitioned by the plurality of composition lines is detected to be a specified value (for example, the golden ratio).

Abstract: Provided is a biomarker that enables easy and rapid detection of oxidative stress on a living organism and enables prevention of tissue damage or cell necrosis by drug administration, and which is a powerful marker for the study of toxicity and pharmacokinetics of various agents. Oxidative stress is determined by measuring blood concentration of ophthalmic acid, which is a substance that varies in blood depending on the variation of reduced glutathione (GSH) concentration in a biological sample with the use of an analyzer such as a capillary electrophoresis-mass spectrometer. Further, an anti-oxidative stress agent is screened by administering an anti-oxidative stress candidate agent to a non-human animal under oxidative stress conditions, measuring blood concentration of ophthalmic acid, and evaluating the degree of decrease in the ophthalmic acid concentration.

Abstract: To provide peptides having high affinity for hemagglutinin and peptides having high inhibitory activity against influenza virus infection, as well as pharmaceutical compositions containing the peptides, the polypeptides having any one of SEQ ID NOs: 2 to 7, 9 to 10, and 12 to 18 are obtained by introducing mutation into a peptide having the sequence of ARLSPTMVHPNGAQP (peptide A-1: SEQ ID NO: 1) and screening for peptides having higher affinity for hemagglutinin. Further, the inhibitory activity of the peptide of SEQ ID NO: 3 against influenza virus infection can be enhanced by truncating SEQ ID NO: 3 in its C-terminus region with leaving ARLPR (SEQ ID NO: 44) or ARLP (SEQ ID NO: 52). In addition, an influenza virus-infection inhibitor and an influenza preventive/therapeutic agent can be prepared by formulating these influenza virus receptor-binding peptides.

Abstract: By culturing hematopoietic stem cells in the presence of SFRP-F protein, hematopoietic stem cells for hematopoietic stem cell transplantation can be produced.

Abstract: In the electronic circuit device with stacked plural components of the same function, this invention enables to select an arbitrary component among plural components by a control element, without setting pre-determined identification information in each component. By installing a sequential logic circuit in each component, and changing a state of the sequential logic circuit by control data transmitted from the component stacked in a preceding stage or the control element, the state of the controlled component is set to a state that accepts a selection made by the control element.

Abstract: An assigning molecule obtained by ligating a genotype molecule to a phenotype molecule by transpeptidation, wherein the genotype molecule is constructed by bonding (a) a spacer molecule comprising a donor region which can be bonded to a 3?-terminal end of nucleic acid, a PEG region bonded to the donor region and a peptide acceptor region which is bonded to the PEG region, to (b) a 3? end of a nucleic acid comprising a 5? untranslated region comprising a transcription promoter and a translation enhancer; an ORF region which comprises a polyA sequence and which is bonded to the 3?-terminal side of the 5? untranslated region; and a 3?-terminal region that is bonded to the 3?-terminal side of the ORF region.

Abstract: An electronic circuit, for which a coil 22 is disposed being overlapped with a region of a memory array 11, carries out communications by inductive coupling between stacked and mounted chips by means of the coil 22. Because each side of the coil 22 is disposed so as not to be parallel to a word line and a bit line 15, crosstalk between ‘the coil 22’ and ‘the word line 14 and bit line 15’ can minimized. This allows efficiently arranging a coil to carry out communications by inductive coupling between chips to be stacked and mounted.