Patents Assigned to Lion Corporation
  • Patent number: 5032523
    Abstract: A process for separating an optically active substanbce comprising the steps of:(a) effecting a transesterification reaction between an ester of a linear or branched aliphatic racemic alcohol and an alcohol in an organic solvent containing an enzyme suspended therein; and(b) separating an optically active compound from the resultant reaction mixture.
    Type: Grant
    Filed: January 12, 1988
    Date of Patent: July 16, 1991
    Assignee: Lion Corporation
    Inventors: Masaki Amano, Haruhiko Toda, Minako Yasu, Toshiyuki Koyagi
  • Patent number: 5012012
    Abstract: An alkoxylation catalyst for causing an alkylene oxide to react with an organic compound having one or more active hydrogen, comprising magnesium oxide modified by the addition of at least one metal ion selected from the group consisting of Al.sup.3+, Ga.sup.3+, In.sup.3+, Tl.sup.3+, Co.sup.3+, Sc.sup.3+, La.sup.3+, and Mn.sup.2+. In the presence of the catalyst, an addition polymerization reaction between the alkylene oxide and the organic compound having one or more active hydrogen such as an alcohol or phenol can be performed with only small amounts of unreacted material and byproducts, and the alkylene oxide adduct having a very narrow alkylene oxide adduct distribution can be obtained.
    Type: Grant
    Filed: April 25, 1989
    Date of Patent: April 30, 1991
    Assignee: Lion Corporation
    Inventors: Hirofumi Nakamura, Yuichi Nakamoto, Yuji Fujimori
  • Patent number: 5008295
    Abstract: A method of inhibiting the growth of cancers susceptible to treatment with .alpha.-carotene, which comprises: administering an effective cancer cell growth inhibiting amount of .alpha.-carotene to a manmal having said cancer cells.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: April 16, 1991
    Assignee: Lion Corporation
    Inventors: Hoyoku Nishino, Ryozo Iwasaki, Akio Okabe, Yuki Yogo
  • Patent number: 4996307
    Abstract: A water-soluble acylated chitosan having a degree of acylation of 35 to 65% is prepared by dissolving a water-insoluble chitosan in the form of a random copolymer having a degree of deacetylation of at least 70% in an aqueous acid solution, diluting the solution with water or a water-miscible solvent such as methanol, and adding an acylation agent such as acetic anhydride to the diluted solution. The acylated chitosan is obtained in high yields within a few hours at about room temperature.
    Type: Grant
    Filed: June 25, 1986
    Date of Patent: February 26, 1991
    Assignee: Lion Corporation
    Inventors: Hiroshi Itoi, Hiroshi Sano, Kenichiro Shibasaki
  • Patent number: 4996191
    Abstract: An etchant containing 1-hydroxy-ethane-1,1-diphosphonic acid is useful in etching Ba--Cu--O and Ca--Cu--O high-temperature superconductors.
    Type: Grant
    Filed: December 15, 1988
    Date of Patent: February 26, 1991
    Assignee: Lion Corporation
    Inventors: Takeshi Kobayashi, Masayoshi Tonouchi, Yoshiyuki Sakaguchi
  • Patent number: 4994414
    Abstract: A method of producing bioactive ceramics containing apatite crystal useful for artificial tooth roots or artificial bones, which comprises the steps of(i) reacting (A) at least one type of silicic acid ester such as tetramethoxysilane or tetraethoxysilane; (B) at least one type of phosphorus compound represented by general formula (II), (III), or (V): ##STR1## (where each of R.sub.5 to R.sub.9 is hydrogen, an alkyl group, with 1 to 5 carbon atoms, a phenyl radical, or an aralkyl group with 7 to 10 carbon atoms in which at least one of R.sub.10 to R.sub.12 is hydrogen, and m: 0 type 10); and (C) at least one water soluble calcium salt, the reaction being carried out in the presence of water at at pH of not higher than 8 to prepare a gel; and(ii) sintering the resulting gel to obtain the bioactive ceramics containing not less than 5 wt% of apatite and not more than 2wt% of Na compound as NA.sub.2 O.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: February 19, 1991
    Assignee: Lion Corporation
    Inventors: Nobuyuki Yamamoto, Tsuyoshi Goto, Yasunobu Horiguchi
  • Patent number: 4978681
    Abstract: A hair-growing agent which exhibits a strong hair-growing effect. The hair-growing agent according to the present invention contains as an effective ingredient an aliphatic carboxylic acid having an odd number of carbon atoms or a derivative thereof.
    Type: Grant
    Filed: August 16, 1988
    Date of Patent: December 18, 1990
    Assignee: Lion Corporation
    Inventors: Kuniaki Adachi, Hideo Tamai, Masanao Sadai
  • Patent number: 4976369
    Abstract: A container used for selling powders such as a washing powder and the like comprises a main body for filling the powders therein and a lid member for covering an upper opening of the main body. A band member is disposed through a score at a peripheral edge of the lid member except at a part of the peripheral edge thereof and has a peeling-off projection formed at its end. A picking-up projection is disposed at a wall of the lid member just above a space where no band member is defined. Each of these projections has a rectangular shape and has opposite surfaces. The surfaces of the peeling-off and picking-up projection are at approximately right angles to each other. These projections serve to protect one another from impacts or shocks exerted on one another. As the result, these projections are prevented them from deformation. Therefore, the container gives confidence that it can be opened by the impacts or the shocks exerted thereon at ease.
    Type: Grant
    Filed: November 14, 1988
    Date of Patent: December 11, 1990
    Assignee: Lion Corporation
    Inventors: Nobuaki Shindo, Seiji Naruse, Fumiaki Maeda, Yuujirou Miyamoto, Toshio Takeuchi
  • Patent number: 4975275
    Abstract: A hair conditioning composition comprising a guanidine derivative having an amide group in its molecule or a salt thereof as an active ingredient is effective to render damaged hair soft and moist.
    Type: Grant
    Filed: November 27, 1989
    Date of Patent: December 4, 1990
    Assignee: Lion Corporation
    Inventors: Joji Mitamura, Hideo Kurokawa
  • Patent number: 4971726
    Abstract: An electroconductive resin composition comprising (i) 100 parts by weight of thermoplastic resins and/or thermosetting resins and (ii) 15 to 150 parts by weight of (a) carbon black having a DPB oil absorption amount of 400 ml/100 g or more and (b) expanded graphite having an average particle size of 40 .mu.m or more, wherein the expanded graphite content is 40 to 90% by weight of the total amount of the carbon black and the expanded graphite.
    Type: Grant
    Filed: June 29, 1988
    Date of Patent: November 20, 1990
    Assignee: Lion Corporation
    Inventors: Seiji Maeno, Hidetaka Ozaki, Yasuo Takamizu
  • Patent number: 4970017
    Abstract: A process for producing a granular detergent composition having a high bulk density comprising the steps of:(i) kneading detergent ingredients to form a kneaded solid detergent mixture;(ii) disintegrating the solid detergent mixture; and(iii) coating the disintegrated granular detergent composition with water-insoluble finely divided powder particles having an average primary particle diameter of 10 .mu.m or less.
    Type: Grant
    Filed: December 16, 1988
    Date of Patent: November 13, 1990
    Assignee: Lion Corporation
    Inventors: Masayoshi Nakamura, Noboru Hara, Kazuo Nagoh, Yuji Tai
  • Patent number: 4968539
    Abstract: A polymer membrane for delivering a drug is provided. The membrane is capable of regulating the delivery of the drug and comprises (A) a porous hydrophobic polymer membrane having a pore diameter of not larger than 3 .mu.m and a porosity of 10 to 90% which is immobilized with (B) a specific liquid crystal-forming compound having a gel/liquid crystal transition temperature in the range of 25.degree. to 45.degree. C.
    Type: Grant
    Filed: November 30, 1988
    Date of Patent: November 6, 1990
    Assignee: Lion Corporation
    Inventors: Takao Aoyagi, Shuji Sato, Minako Yasu, Iwao Nozawa, Yousuke Suzuki
  • Patent number: 4959104
    Abstract: A self-hardenable material comprising a calcium phosphate having an atomic ratio of Ca/P of 1.4 to 1.6, a difficultly water-soluble inorganic fluoride, an organic or inorganic acid and water is provided. For example, when the hardenable material is frilled in the form of slurry or paste in a necessary part in vivo or in the dental cavity, it hardens within a short time to form a stable apatite type product.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: September 25, 1990
    Assignees: Mitsui Toatsu Chemicals, Inc., Lion Corporation
    Inventors: Shinji Iino, Minoru Oshima, Shinya Kitoh, Toshiaki Kobayashi
  • Patent number: 4954341
    Abstract: A hair cosmetic composition comprising:(A) 0.05% to 10% by weight of at least one quaternary ammonium salt having the formula: ##STR1## wherein R.sub.1 is an alkenyl having 14 to 20 carbon atoms, R.sub.2 is an alkyl or alkenyl having 14 to 20 carbon atoms, R.sub.3 and R.sub.4 are independently methyl, ethyl, a polyoxyethylene having an average polymerization degree of 1 to 5, or a polyoxypropylene having an average polymerization degree of 1 to 5, and X.sup.- is an anion, and having an iodine value of 35 to 100; and(B) 0.05% to 10% by weight of a phosphate having the formula: ##STR2## wherein R.sub.5 is a linear alkyl having 1 to 22 carbon atoms, a hydroxyalkyl having 1 to 22 carbon atoms, an alkenyl having 2 to 22 carbon atoms, an alkylphenyl having 7 to 22 carbon atoms, or glyceryl, R.sub.6 is hydrogen or methyl, R.sub.7 is hydrogen, an alkali metal, a C.sub.1 -C.sub.20 alkyl-substituted ammonium, or a C.sub.1 -C.sub.20 hydroxyalkyl-substituted ammonium, R.sub.8 is a group having the formula ##STR3## or R.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: September 4, 1990
    Assignee: Lion Corporation
    Inventors: Sigemi Nakamura, Hideo Kurokawa, Jouji Mitamura
  • Patent number: 4948520
    Abstract: A softener composition comprises a mixture of (A) a mono(long-chain) quaternary ammonium salt such as monotallowalkyl trimethyl ammonium chloride, (B) a di(long-chain) quaternary ammonium salt such as ditallowalkyl dimethyl ammonium chloride and (C) a tri(long-chain) quaternary ammonium salt such as tritallowalkyl monomethyl ammonium chloride), the weight ratio of the components (A):(B):(C) falling within the range of from 2 to 30: 96 to 50: 2 to 20, and iodine value of the mixture being in the range of 35 to 100; and (D) a polyoxyethylene adducted nonionic surfactant such as polyoxyethylene octylphenyl ether (P=40). The softener composition improves the softness of natural fibers without impairing the water absorption properties thereof. It also improves the softness of chemical fibers and gives them excellent antistatic property.
    Type: Grant
    Filed: September 1, 1987
    Date of Patent: August 14, 1990
    Assignee: Lion Corporation
    Inventor: Hisami Sasaki
  • Patent number: 4943612
    Abstract: An ultra-fine particulated polymer latex having an average particle size of 100 nm or less, a crosslinked structure and a glass transition temperature lower than a value calculated by a weight fraction method.
    Type: Grant
    Filed: December 3, 1987
    Date of Patent: July 24, 1990
    Assignee: Lion Corporation
    Inventors: Hiroshi Morita, Eiichi Hirota, Yasuo Ishizaki
  • Patent number: 4931562
    Abstract: A bleaching composition comprises:(A) hydrogen peroxide and/or a hydrogen peroxide addition compound such as a percarbonate; and(B) at least one activator which is a nitrogen-containing heterocyclic compound in which a halogen atom is substituted for the hydrogen atom of the secondary amino group or a non-heterocyclic N-halo-hindered amine compound, the hydrolysis constant of the activator being within the range of 1.times.10.sup.-10 to 5.times.10.sup.-6 (at 25.degree. C.). Examples of the activator include 1-chloro-piperidine, 1-chloro-2-methyl-piperidine, 1-chloro-isonipecotic acid, 1-chloro- -hexamethyleneimine and 1-chloro-.epsilon.-caprolactam. The bleaching-detergent composition may also contain the components (A) and (B) together with a surfactant. These compositions exhibit an excellent effect concerning bleaching at low temperature, but hardly affect the colors of colored and patterned clothes.
    Type: Grant
    Filed: January 11, 1989
    Date of Patent: June 5, 1990
    Assignees: Lion Corporation, Sankyo Company Limited
    Inventors: Yasuhiro Akabane, Takamitsu Tamura, Masami Fujiwara
  • Patent number: 4925976
    Abstract: A method for sulfonating olefins comprising the steps of mixing (A) internal olefins having 8 to 22 carbon atoms with (B) alpha-olefins having an average carbon atom number, larger by 3 to 7 than that of the internal olefins (A) in a weight ratio of (A)/(B)=95/5 to 5/95, and sulfonating the resultant mixture with a sulfonating agent. Thus, internal olefins can be sulfonated at a high conversion.
    Type: Grant
    Filed: March 26, 1986
    Date of Patent: May 15, 1990
    Assignee: Lion Corporation
    Inventors: Toshimi Terao, Kentaro Kiyama, Kyozo Kitano
  • Patent number: 4923400
    Abstract: A dental adhesive composition containing a compound having the formula (I): ##STR1##
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: May 8, 1990
    Assignee: Lion Corporation
    Inventors: Kunitomo Suzuki, Takao Kiyohara, Shinya Kitoh
  • Patent number: 4913895
    Abstract: An oral composition comprising (i) at least one phosphate selected from the group consisting of linear polyphosphates of the formula (I):M.sub.n+2 P.sub.n O.sub.3n+l (I)wherein M represents Na or K and N .gtoreq.2, and cyclic polyphosphates of the formula (II):(M'PO.sub.3).sub.m (II)wherein M' represents Na or K and m.gtoreq.3 and (iii) l-menthol, anethol, or the mixture thereof in an aqueous medium. This oral composition has an excellent antibacterial effect and prevents the development of calculus and periodontal diseases.
    Type: Grant
    Filed: July 22, 1987
    Date of Patent: April 3, 1990
    Assignee: Lion Corporation
    Inventors: Mikio Miyake, Akinori Takahashi