Patents Assigned to Lion Corporation
  • Patent number: 5409709
    Abstract: An ibuprofen-containing antipyretic analgesic preparation blending 0.01-30 parts by weight of acetaminophen based on 1 part by weight of ibuprofen, 0.05-100 parts by weight of magnesium-based antacids based on 1 part by weight of the total amount of ibuprofen and acetaminophen, and/or 0.01-30 parts by weight of at least one sedative selected from bromovalerylurea and allylisopropylacetylurea based on 1 part by weight of ibuprofen.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: April 25, 1995
    Assignee: Lion Corporation
    Inventors: Kiyotaka Ozawa, Ryoko Sugita, Kiyo Adachi, Tomiyuki Yanase, Syuichi Ueda, Aya Yamane
  • Patent number: 5384189
    Abstract: A water-decomposable non-woven fabric comprises a water-dispersible fiber layer, each fiber of which is bound with one another using a water-soluble binder comprising an unsaturated carboxylic acid/unsaturated carboxylic acid ester copolymer in which 1 to 60 mole % of the repeating units derived from the unsaturated carboxylic acid is in the form of a salt and which is soluble in tap water but is insoluble in an aqueous solution containing not less than 0.5% by weight of a neutral inorganic salt comprising a monovalent ion; the water-dispersible fiber layer being composed of a mixture of 40 to 90% by weight of fibers having a crimp number of 19/inch or less, 10 to 60% by weight of fibers having a crimp number of 20/inch to 25/inch, and not more than 10% by weight of fibers having a crimp number of 26/inch or more; and a content of the binder in the non-woven fabric being 1 to 30% by weight relative to the total weight of the non-woven fabric.
    Type: Grant
    Filed: January 27, 1993
    Date of Patent: January 24, 1995
    Assignee: Lion Corporation
    Inventors: Hideo Kuroda, Yasunori Sakamoto
  • Patent number: 5378453
    Abstract: A composition for preventing graying of the hair and restoring grayed hair to its natural color comprises an effective amount of one member selected from the group consisting of cAMP compounds such as 8-butylthio cAMP-Na or 8-methoxy cAMP-Na and water. The composition can prevent graying of the hair and restoring grayed hair to its natural color upon application to the scalp, the effective component is very stable even in the form of compositions containing water and the composition does not cause quality deteriorations such as giving out of bad smell.
    Type: Grant
    Filed: March 7, 1994
    Date of Patent: January 3, 1995
    Assignee: Lion Corporation
    Inventors: Keikichi Sugiyama, Koji Takada, Ikuo Yamamoto
  • Patent number: 5376643
    Abstract: Methods and compositions for restoring grayed hair to its natural color comprising at least one compound of the formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 may be the same or different and each represents a hydrogen atom, an acyl group having 5 to 15 carbon atoms derived from a monocarboxylic acid having 5 to 15 carbon atoms or an acyl group having 2 to 15 carbon atoms derived from a dicarboxylic acid having 2 to 15 carbon atoms or an alkyl group having 1 to 2 carbon atoms; X.sub.1 and X.sub.2, respectively, represent a hydrogen atom, a halogen, or a mercapto group; with the proviso that when R.sub.1, R.sub.2 and R.sub.3 and X.sub.1 are hydrogen atoms at the same time, X.sub.2 is not a halogen atom or a mercapto group, and M.sub.1 represents a hydrogen atom, an alkali metal or tris(hydroxymethyl)aminomethane.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: December 27, 1994
    Assignee: Lion Corporation
    Inventors: Keikichi Sugiyama, Koji Takada, Ikuo Yamamoto
  • Patent number: 5374750
    Abstract: In a method of manufacturing fatty acid esters of polyoxyalkylene alkyl ethers, fatty acid alkyl ester is reacted with alkylene oxide in the presence of a catalyst consisting essentially of a magnesium oxide added with at least one metal ion selected from the group consisting of Al.sup.3+, Ga.sup.3+, In.sup.3+, Tl.sup.3+, Co.sup.3+, Sc.sup.3+, La.sup.3+, and Mn.sup.2+ to manufacture a compound having the following formula: ##STR1## wherein each of R.sub.1 and R.sub.3 independently represents an alkyl group, R.sub.2 represents an alkylene group, and n is a positive integer.
    Type: Grant
    Filed: September 1, 1993
    Date of Patent: December 20, 1994
    Assignee: Lion Corporation
    Inventors: Hirofumi Nakamura, Itsuo Hama, Yuji Fujimori, Yuichi Nakamoto
  • Patent number: 5352450
    Abstract: A method for preparing a vaccine for dental caries comprises the step of culturing a variant which is obtained by integrating a protein antigen (PAc)-expressing gene into the chromosomal gene of a Streptococcus mutans GS-5 strain to obtain the protein antigen, the protein antigen being produced on the surface of cells of oral Streptococcus mutans or it being extracellularly produced by the microorganism and having a molecular weight ranging from about 170,000 to 220,000. Streptococcus mutans GS-5 (K-3), in which a protein antigen-expressing gene is integrated into the chromosomal gene thereof, has an ability of producing the protein antigen on the surface of the cells or extracellularly. A preventive vaccine composition for dental caries for nasal drops comprises the protein antigen thus produced by the strain: Streptcoccus mutans, the vaccine being intranasally administered. The method makes it possible to enhance the yield of PAc and to simplify processes for purifying PAc.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: October 4, 1994
    Assignees: Lion Corporation, National Institute of Health
    Inventors: Toshihiko Koga, Nobuo Okahashi, Ichiro Takahashi, Koji Shibuya, Hirotaka Ohta
  • Patent number: 5348733
    Abstract: An oral composition comprises triclosan, an alkyl sulfate and a water-soluble tin salt, whereby triclosan can be stably formulated to exert its effect.
    Type: Grant
    Filed: November 5, 1992
    Date of Patent: September 20, 1994
    Assignee: Lion Corporation
    Inventors: Seiji Morishima, Miwako Oka, Yamazaki Yoji
  • Patent number: 5346543
    Abstract: A deinking agent comprises a compound of the following formula (I);N(R.sup.1)(R.sup.1) R.sup.2 (I)wherein R.sup.1 is --C(O)R.sup.4 or --(C.sub.2 H.sub.4 O)C(O)R.sup.4 ; R.sup.2 is --(C.sub.2 H.sub.4 O)--(AO).sub.m or --(AO).sub.m ; R.sup.3 is --C(O)R.sup.4 or --(C.sub.2 H.sub.4 O)C(O)R.sup.4 ; R.sup.4 is C.sub.9-23 alkyl or C.sub.9-23 alkenyl; m is a integer from 40 to 100 and A is C.sub.2-4 alkylene, and a quaternary ammonium compound thereof in a molar ratio of 9/1 to 1/9. The deinking agent for reclaiming printed waste paper has abilities to efficiently release the ink from the waste paper in the disintegration process and to collect the ink and produce suitable foam in the flotation process, which provides high quality reclaimed pulp having high whiteness and a low content of remaining ink.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: September 13, 1994
    Assignee: Lion Corporation
    Inventors: Yoshie Hirakouchi, Ikuo Adachi, Yoshiaki Nagai
  • Patent number: 5328491
    Abstract: A dispersant comprises a polystyrenesulfonic acid having a weight-average molecular weight in the range of 2,000 to 100,000 or a salt thereof, wherein at least 70% of the terminals of the polymer chain have an indane ring of the formula (I): ##STR1## wherein X represents a cation selected from the group consisting of a hydrogen, alkali metals, alkaline earth metals, ammonium and organic amines, and n and m each represent 0 or an integer of at least 1. The dispersant has excellent properties of dispersing organic and inorganic substances and an effect of remarkably improving the stability of a dispersion system such as a coal/water slurry.
    Type: Grant
    Filed: June 27, 1991
    Date of Patent: July 12, 1994
    Assignee: Lion Corporation
    Inventors: Junichi Yamada, Mituo Sugiyama, Tadashi Iihara
  • Patent number: 5319062
    Abstract: An improvement is proposed in the curing method of an epoxy resin by the admixture of a polyamide as a crosslinking curing agent, in which the curing agent as well as the epoxy resin composition with admixture of the curing agent has an outstandingly low viscosity as compared with the use of a conventional polyamide to facilitate handling. The improvement can be obtained by using, as the polyamide, a condensation reaction product between (A) an alkylene polyamine having 4 to 20 carbon atoms in a molecule and (B) a dimeric acid mixture containing at least 50% by weight of a non-cyclic dimeric acid or an alkyl ester thereof represented by the general formula ##STR1## in which each R is, independently from the other, a hydrogen atom or a C.sub.1-4 alkyl group obtained by the dimerization reaction of oleic acid or an alkyl ester thereof. When flexibility or bendability is desired of the cured epoxy resin, the condensation reaction is performed, in addition to the reactants (A) and (B), with admixture of a C.sub.
    Type: Grant
    Filed: July 30, 1992
    Date of Patent: June 7, 1994
    Assignee: Lion Corporation
    Inventors: Hitoshi Kigawa, Akira Ohishida
  • Patent number: 5318776
    Abstract: A composition for preventing graying of the hair and restoring grayed hair to its natural color comprises an effective amount of one member selected from the group consisting of cAMP compounds such as 8-butylthio cAMP-Na or 8-methoxy cAMP-Na and water. The composition can prevent graying of the hair and restoring grayed hair to its natural color upon application to the scalp, the effective component is very stable even in the form of compositions containing water and the composition does not cause quality deteriorations such as giving out of bad smell.
    Type: Grant
    Filed: April 27, 1993
    Date of Patent: June 7, 1994
    Assignee: Lion Corporation
    Inventors: Keikichi Sugiyama, Koji Takada, Ikuo Yamamoto
  • Patent number: 5317063
    Abstract: A water-soluble polymer sensitive to salts is a copolymer of (A) 10 to 90% of acrylic acid and/or methacrylic acid; and (B) 90 to 10% of a vinyl monomer of Formula (I): ##STR1## (wherein R represents a hydrogen atom or a methyl group; and R.sup.1 represents an aryl group or a cycloalkyl group); or the foregoing component (A); (B) 2 to 70% of a vinyl monomer of Formula (II): ##STR2## (wherein R.sup.2 represents an alkyl group, an aryl group or a cycloalkyl group); and (C) 2 to 40% of a vinyl monomer of Formula (III): ##STR3## (wherein R.sup.3 represents an aryl group), 2 to 70 mole % of the repeating units derived from the acrylic acid and/or methacrylic acid being in the form of a salt. It is soluble in tap water, but insoluble in an aqueous solution containing not less than 0.5% of an inorganic salt of a monovalent ion.
    Type: Grant
    Filed: February 19, 1991
    Date of Patent: May 31, 1994
    Assignee: Lion Corporation
    Inventors: Masanori Komatsu, Yasuo Iida
  • Patent number: 5316758
    Abstract: An oral composition comprises a nonionic antimicrobial or germicidal agent and at least one amphoteric surface active agent selected from the group consisting of compounds of the following general formulae (1) and (2): ##STR1## wherein R represents an alkyl group having 1 to 18 carbon atoms, and n and m are independently an integer of from 1 to 10. The composition preferably further comprises an alkyl sulfate.
    Type: Grant
    Filed: November 5, 1992
    Date of Patent: May 31, 1994
    Assignee: Lion Corporation
    Inventors: Seiji Morishima, Yoji Yamazaki
  • Patent number: 5312883
    Abstract: A water-soluble polymer which is soluble in tap water, but insoluble in an aqueous solution containing 0.5% or more of a neutral inorganic salt, which is a copolymer of:(A) 30 to 75% by weight of acrylic acid,(B) 5 to 30% by weight of a vinyl monomer represented by the following general formula [1]:CH.sub.2 .dbd.C(R)COOR.sup.1 [1]wherein R represents a hydrogen atom or a methyl group; and R.sup.1 represents an alkyl group having 8 to 12 carbon atoms, and(C) 20 to 40% by weight of a vinyl monomer represented by the following general formula [2]:CH.sub.2 .dbd.C(R.sup.2)COOR.sup.3 [2]wherein R.sup.2 represents a hydrogen atom or a methyl group; and R.sup.3 represents an alkyl group having 2 to 4 carbon atomsand in which not more than 50 molar % of the repeating units of derived from the acrylic acid is in the form of a salt. When the polymer is used as a binder for a non-woven fabric or paper, it exhibits satisfactory strength and permeability to a body fluid when the resultant product is wet with body fluid.
    Type: Grant
    Filed: November 5, 1992
    Date of Patent: May 17, 1994
    Assignee: Lion Corporation
    Inventors: Masanori Komatsu, Ikuko Toki
  • Patent number: 5292941
    Abstract: A method for ozonizing an unsaturated fatty acid or a lower alkyl ester thereof is provided as comprising the steps of: supplying an unsaturated fatty acid or a lower alkyl ester thereof as a thin film stream, and passing a gas containing ozone in oxygen or a mixture of oxygen and air or inert gas in the same direction as the flow direction of said thin film stream, thereby achieving gas-liquid contact between the thin film stream of unsaturated fatty acid or lower alkyl ester thereof and the ozone-containing gas. Also provided is a method for oxidative decomposition of the thus ozonized product by contact with ozone-free oxygen gas or air.
    Type: Grant
    Filed: January 27, 1993
    Date of Patent: March 8, 1994
    Assignee: Lion Corporation
    Inventors: Hitoshi Kigawa, Hiroshi Yamaya, Yurie Iino
  • Patent number: 5261537
    Abstract: A container used for containing powders such as a washing powder and the like has bottom stopper means for fixedly supporting another container when another container is inserted into the container. When a lot of containers are stored before containing contents therein, many can be stacked on top of one another. With these containers, the space needed for storing can be reduced.
    Type: Grant
    Filed: April 29, 1991
    Date of Patent: November 16, 1993
    Assignee: Lion Corporation
    Inventors: Nobuaki Shindo, Seiji Naruse, Fumiaki Maeda, Yuujirou Miyamoto, Toshio Takeuchi
  • Patent number: 5258167
    Abstract: An extractant for extracting rare earth metal ions comprises, for instance, di-(3-methylcyclohexyl)phosphoric acid, di-1-ethylpentylphosphoric acid, docosyl-(2 isopropyl-5-methylcyclohexyl) phosphoric acid, 2-ethylhexyl-2-methylcyclohexylphosphoric acid and/or 2-hexyloctyl-cyclohexylphosphoric acid or a combination of, for instance, dicyclohexylphosphoric acid and di-(2-heptylundecyl) phosphoric acid. A method for extracting rare earth metals comprises the step of bringing an acidic aqueous solution containing ions of rare earth metals into contact with an extraction medium containing an extractant exemplified above to transfer the rare earth metal ions to the extraction medium. The extractant not only exhibits high extractability for rare earth metal ions but also facilitates the back extraction of the rare earth metal ions therefrom.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: November 2, 1993
    Assignee: Lion Corporation
    Inventors: Toshio Takahashi, Hiroaki Nishizawa, Yukari Ishii
  • Patent number: 5246629
    Abstract: A liquid detergent composition contains:(A) an anionic surfactant having the formula (I):RO(CH.sub.2 CH.sub.2 O).sub.n SO.sub.3 M (I)wherein R is a C.sub.10 -C.sub.18 alkyl or alkenyl group,n is 0 to 5, andM is hydrogen, an alkaline metal cation, an alkaline earth metal cation, an ammonium cation or a substituted ammonium cation; and(B) an amphoteric ion surfactant having the formula (II): ##STR1## wherein R' is a C.sub.10 -C.sub.16 alkyl or alkenyl group, provided that the weight ratio of component (A) to a total amount of components (A) and (B) is 0.2 to 0.8 and the total amount of components (A) and (B) is 0.05% to 0.3% by weight.
    Type: Grant
    Filed: July 19, 1991
    Date of Patent: September 21, 1993
    Assignee: Lion Corporation
    Inventors: Yoshinori Fukumoto, Yoko Miyashita, Takashi Nishino, Seiichi Ota
  • Patent number: 5232755
    Abstract: A laminated tube container has the body comprising a sheet material comprising a substrate, a silicon oxide deposited layer, a heat buffer layer and an extruded coating layer of a thermoadhesive resin which are successively formed in a laminate. The heat buffer layer prevents cracks from being produced in the silicon oxide deposited layer by the heat coming when the extruded coating layer of a thermoadhesive resin is laminated. The heat buffer layer is preferably formed by dry lamination or non-solvent lamination which requires no heating. An anchor coat layer may optionally be provided between the heat buffer layer and the extruded coating layer of a thermoadhesive resin so that the adhesion strength between these layers can be improved.
    Type: Grant
    Filed: September 11, 1991
    Date of Patent: August 3, 1993
    Assignees: Toppan Printing Co., Ltd., Lion Corporation
    Inventors: Yuji Komiya, Hiroyuki Uchiumi, Shintaro Ohashi, Akio Kuboniwa
  • Patent number: 5219549
    Abstract: A bleaching detergent composition is disclosed which contains granulated sodium percarbonate incorporated therein formed by separately spraying an aqueous boric acid solution and an aqueous alkali metal silicate solution onto sodium percarbonate particles kept in a fluidized state to coat the sodium percarbonate particles with an aqueous solution of the boric acid and the alkali metal silicate.
    Type: Grant
    Filed: May 6, 1991
    Date of Patent: June 15, 1993
    Assignees: Mitsubishi Gas Chemical Company, Inc., Lion Corporation
    Inventors: Masayoshi Onda, Akira Ito, Yasuo Hiro, Kenji Umehara, Yuji Yoneyama