Abstract: The present invention relates, in part, to methods for detecting nuclease activity, such as the activity of Cas nucleases. Also described herein are compositions for conducting assays, as well as methods for conducting assays in the presence of test compounds.

Abstract: Methods, computer systems, computer-storage media, and graphical user interfaces are provided for facilitating data transformations, according to embodiments of the present invention. In one embodiment, a set of example values including example input values that indicate data values to be transformed and example output values that indicate a desired form in which to transform data. Based on the set of example values, a data transformation function that is relevant to the set of example values is identified. The data transformation function is used to generate a transformation program to transform the example input values to the desired form in which to transform data. A suggestion of the transformation program can be provided to a user device, wherein selection of the transformation program suggestion results in a data transformation.

Abstract: A system and method is provided for displaying surfaces of an object from a vantage point different from the vantage point from which imagery of the object was captured. In some aspects, imagery may be generated for display by combining visual characteristics from multiple source images and applying greater weight to the visual characteristics of some of the source images relative to the other source images. The weight may be based on the orientation of the surface relative to the location from which the image was captured and the location from which the object will be displayed.

Abstract: A method of forming a high voltage optical transformer includes forming a via through a transparent carrier wafer, forming a conductive layer within the via, bonding a solid state lighting (SSL) package to a first side of the carrier wafer, and bonding a photovoltaic (PV) wafer to a second side of the carrier wafer opposite to the first side. The photovoltaic wafer may include an active area and a conductive area located outside of the active area that is in electrical contact with the conductive layer. The method further includes forming both an SSL contact with the solid state lighting package and a PV contact with the conductive layer on the same side of the carrier wafer.

Abstract: Disclosed herein are system, method, and computer program product embodiments for replicating a remote venue in a local venue. An embodiment operates by receiving original audio. Thereafter, the original stream of audio is modified to produce modified audio based on an audio profile unique to a remote venue smaller than the local venue. The audio profile comprises a virtual representation of the remote venue including (i) a virtual audio source corresponding to the local venue's audio source and configured to produce the original audio and (ii) a virtual reverberation point corresponding to a real-world location in the remote venue and the portion of the local venue. As such, the modified audio is determined based on receipt of the original audio from the reverberation point. Thus, after correlating the modified audio to the local venue's audio source, the modified audio is provided by the audio source to the portion of the local venue.

Abstract: A graphite article formed of a creped graphite sheet is provided. The creped graphite sheet has a first major surface and a second major surface oppositely disposed to the first major surface and a plurality of macrofolds, each macrofold having a plurality of associated microfolds, wherein each microfold is smaller than the associated macrofold. The creped graphite article has improved flexibility as compared to a graphite sheet which has not been creped. The creped graphite sheet can be formed of a sheet of flexible natural graphite or a sheet of synthetic graphite.

Abstract: Methods and devices for long-duration electricity storage using low-cost thermal energy storage and high-efficiency power cycle, are disclosed. In some embodiments it has the potential for superior long-duration, low-cost energy storage.

Abstract: An elongated vent includes a first piece and a second piece. The first piece has a first upper portion, a first middle portion and a first lower portion. The second piece is a mirror image of the first piece, the second piece having a second upper portion, a second middle portion and a second lower portion. The first and second pieces are joined together at their respective first and second middle portions, wherein each of the first and second middle portions includes a plurality of apertures therethrough, to form a perforated panel. The first and second upper portions form a first channel; the first and second lower portions form a second channel.

Abstract: An apparatus includes a high side heat exchanger, a heat exchanger, a flash tank, a first expansion valve, a second expansion valve, a load, a first compressor, and a second compressor. During a first mode of operation, the second expansion valve directs refrigerant from the flash tank to the load. The refrigerant from the load bypasses the first compressor. The heat exchanger transfers heat from the refrigerant from the high side heat exchanger to the refrigerant from the load. The second compressor compresses the refrigerant from the heat exchanger. During a second mode of operation, the first expansion valve directs refrigerant from the flash tank to the load. The first compressor compresses the refrigerant from the load and the second compressor compresses the refrigerant from the first compressor before the refrigerant from the first compressor reaches the high side heat exchanger.

Abstract: A method includes disposing a semiconductor die between a first high voltage isolation carrier and a second high voltage isolation carrier, disposing a first molding material in a space between the semiconductor die and the first high voltage isolation carrier, and disposing a conductive spacer between the semiconductor die and the second high voltage isolation carrier. The method further includes encapsulating the first molding material and the conductive spacer with a second molding material.

Abstract: A method for emulating a disc swap operation during a play of a legacy game is described. The method includes receiving a user input during the play of the legacy game, determining that the disc swap operation is to be executed based on the user input, and identifying one or more emulated processing unit (PU) code instructions that are included within the disc swap operation during the play of the legacy game. The method further includes compiling, during the play of the legacy game, one or more basic blocks from the one or more emulated PU code instructions, and emulating the disc swap operation. The operation of emulating the disc swap operation includes executing a swap patch emulator.

Abstract: Methods and devices are disclosed for treating neurovascular venous outflow obstructions, with or without implantation of a prosthetic valve. The valve may be carried by a support, such as a stent, which may be self-expandable or balloon expandable. Both transvascular and direct surgical access is contemplated.

Abstract: The present disclosure relates to compositions and methods for modulating gene expression and in particular to compositions and methods for increasing expression of Klotho. For example, the present disclosure provides methods for increasing expression of a Klotho gene in a human cell comprising introducing into the cell a CRISPR enzyme and a guide RNA comprising a guide sequence that is substantially complementary to a target sequence within or near the Klotho gene, wherein the guide RNA or the CRISPR enzyme associates with a transcriptional activation domain.

Abstract: A structured rolled sanitary tissue product having at least two plies, wherein the structured rolled sanitary tissue product has a crumple resistance of less than 30 grams force, a caliper of at least 450 microns/ply, and a bulk softness (TS7) of 10 or less.

Abstract: A social identity system has a collection of physical objects displayed under control of a specific enterprise, a data repository storing, as a virtual object, at least a name and a description of each physical object in the collection, each virtual object associated with a unique Social Identity of Objects (SIO) code, a broad variety of digital information, entered as digital files by registered members, each instance associated with a unique SIO code, and associated by SIO codes, with physical objects in the collection. A portion of the information defined by association with one of the physical objects comprises one or more of history, stories and opinions associated by SIO codes with the members contributing, the changing collection of information over time defining an evolving social identity of the particular one of the physical objects in the collection of physical objects.

Abstract: A computing device displays a data visualization user interface that includes a schema region. Each data field displayed in the schema region is visually associated with a respective data object of a plurality of data objects in an object model. The device receives user input to specify a mathematical expression that includes a first data field from a first object and a second data field from a second object. The first object and the second object are distinct objects in the object model. The device generates a calculated data field based on the mathematical expression. The device assigns the calculated data field as a member of a third object in the object model according to relations in the object model connecting the first object to the second object. The device displays the calculated data field, in the schema region, visually associated with the third object.

Abstract: Methods, systems and apparatus for implementing a quantum gate on a quantum system comprising a second qubit coupled to a first qubit and a third qubit. In one aspect, a method includes evolving a state of the quantum system for a predetermined time, wherein during evolving: the ground and first excited state of the second qubit are separated by a first energy gap ?; the first and second excited state of the second qubit are separated by a second energy gap equal to a first multiple of ? minus qubit anharmoniticity?; the ground and first excited state of the first qubit and third qubit are separated by a third energy gap equal to ??; and the first and second excited state of the first qubit and third qubit are separated by a fourth energy gap equal to the first multiple of the ? minus a second multiple of .

Abstract: One or a plurality of embodiments of the present application provide a system applicable for trip invitation, the system comprising: a server side, comprising a computer-readable storage medium having executable instructions, and a processor communicating with the computer-readable storage medium, wherein the executable instructions are configured to, when executed, cause the processor to: acquire a trip invitation of a first client directed to a second client, wherein the trip invitation comprises identification information of the first client and a location sharing request; and send the trip invitation to the second client.

Abstract: A counter-solar power plant may include a controller configured to execute instructions stored in a memory, the instructions including operations to receive data associated with power outputs of a plurality of legacy solar-only resources (LSORs), determine an estimated power output of the plurality of LSORs based on the received data, obtain a target power delivery profile of the plurality of LSORs, the target power delivery profile including a plurality of target power outputs, determine an output of a CSPP renewable energy system (RES) and a charge/discharge of a CSPP energy storage system (ESS) such that a combined output of the CSPP and the estimated power output of the plurality of LSORs satisfies at least one of the plurality of target power outputs of the target power delivery profile, and control the CSPP RES and CSPP ESS according to the determined CSPP RES output and CSPP ESS charge/discharge.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to redirect internet clients for media monitoring. An example apparatus disclosed herein includes memory, instructions, and processor circuitry to execute the instructions to detect connections between client devices and a first WI-FI connection point, the client devices connected to the first WI-FI connection point via a second WI-FI connection point, when a first number of the connections is less than a second number of possible connections to the first WI-FI connection point, generate an additional connection to the first WI-FI connection point, the additional connection corresponding to at least one of the client devices, and route the client devices to the first WI-FI connection point via the first number of connections and the additional connection.