Abstract: A treatment for autism in which an effective amount of lactulose is administered in order to bind excess ammonia in the gastrointestinal tract, the bloodstream, and the nervous system in order to prevent or reverse ammonia poisoning caused by the administration of certain antibiotics. Lactulose molecules in the colon are fermented by certain bacteria. The fermentation process lowers the colonic pH, and ammonia, in the form of ammonium ions, is used by the bacteria for amino acid and protein synthesis. This lowers the serum ammonia levels and reduces neurotoxicity.

Abstract: A progressing cavity device operates as a motor to impart torque to a bit. A stator of the device defines an internal profile having uphole stages with a first dimension being less than a second dimension of downhole stage. A rotor has an external profile with a constant outer dimension along its length. Disposed in the stator, the rotor defines cavities with the stator and is rotatable with pumped fluid progressing in the cavities from the uphole to downhole to transfer torque to the drive toward the downhole end. Although the rotor is subjected at the downhole end to a reactive torque from the bit, the interference fit of the rotor's constant dimension with the stator's downhole stages is less than with the uphole stages, which can mitigate issues with heat buildup in the downhole stages. The device can also operates as a progressing cavity pump.

Abstract: A radiating beacon system includes a traced wire configured to produce a first magnetic field circulating around the traced wire. The system also includes a radiating beacon configured to produce a second magnetic field circulating around the radiating beacon, wherein the radiating beacon is coupled to the traced wire. The system further includes a locator transmitter configured to apply a tracing signal to the traced wire, wherein the locator transmitter is selectively coupled to the traced wire. The system includes a locator receiver configured to receive the first magnetic field and the second magnetic field, wherein the locator receiver produces an output in response to receiving the first magnetic field and the second magnetic field. Since digital decoders of digital network systems block valves from producing the second magnetic field, an underground irrigation system now includes the radiating beacon system to accurately locate the valves.

Abstract: According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to pump blood in a fluid flow path at a collective rate over 5 liters per minute. The system may include one or more heat exchangers operable to heat at least a portion of the blood to a temperature of at least 42 degrees Celsius and to allow the blood to cool one or more degrees following heating. The system may include one or more convection dialysis modules configured to perform convection dialysis on at least a portion of the blood at least after the one or more heat exchangers allow the blood to cool one or more degrees.

Abstract: Strings of non-volatile memory cells include one or more joint regions adjacent to dummy non-volatile memory cells. During erase operations, different voltage levels are used for different dummy word lines coupled to respective dummy non-volatile memory cells. For example, a selection circuit may set a voltage level of a particular dummy word line to a voltage level greater than a different dummy word line. In another example, the selection circuit may determine a voltage level for a given dummy word line based on a distance between a non-volatile memory cell coupled to the given dummy word line and a selection device included in a string of non-volatile memory cells. Electron holes generated using the dummy word lines during erase operations may neutralize undesired trapped charges in a non-volatile memory string, thereby reducing disparity in erase times for different strings in the non-volatile memory circuit.

Abstract: A new apparatus, system and method to purified produced water and removed valuable metals and minerals is described. The apparatus comprises a device for flowing produced water wellbore from a wellbore to the produced water purification apparatus; at least one device to remove heavy metals from the produced water; at least one brine removal device to remove brine from the produced water. The method comprises steps to use the apparatus and the system comprises a control panel that operates the at least one device for removing heavy metals and at least one sensor in a coordinated manner.

Abstract: A design software, e.g., a graphical user interface (GUI) software, may be used to design and/or configure a load control system. The design software may be executed on a network device (e.g., a personal computer, a laptop, a tablet, or a smart phone). The design software may allow for easy configuration of load control panels and effortless multiplication of configured panels during the design of the load control system. Each load control panel may have a plurality of control devices, such as load control devices (e.g., power modules, dimming modules, and/or switching modules), system controllers, and/or power supplies. The design software may allow for the configuration of load control panels having different types and numbers of control devices. In addition, the design software may allow for the multiplication of load control panels having the same configuration (e.g., the same type and number of control devices).

Abstract: A fishing line management device, including a body defining a passage therethrough, the body defining a first attachment point, a second attachment point, and first and second wings extending therefrom; a substantially triangular keel disposed within the passage; and a rudder movably coupled to the body. The rudder may be selectably positionable at a plurality of preset angular positions, wherein the rudder stays in place once positioned at one of the plurality of preset angular positions.

Abstract: Systems and methods for using neuromuscular information to improve speech recognition. The system includes a plurality of neuromuscular sensors, arranged on one or more wearable devices, wherein the plurality of neuromuscular sensors is configured to continuously record a plurality of neuromuscular signals from a user, at least one storage device configured to store one or more trained statistical models, and at least one computer processor programmed to provide as an input to the one or more trained statistical models, the plurality of neuromuscular signals or signals derived from the plurality of neuromuscular signals, determine based, at least in part, on an output of the one or more trained statistical models, at least one instruction for modifying an operation of a speech recognizer, and provide the at least one instruction to the speech recognizer.

Abstract: Disclosed is a dunnage apparatus, including a converting station and a deflector. The converting station converts a line of high-density supply material into low-density dunnage and ejects the dunnage at an exit in an exit trajectory along a path. The deflector is repositionable with respect to the exit between a first position, in which the deflector is interposed in the path to deflect the path of the dunnage from the exit trajectory to a first deflected trajectory, and a second position. The deflector is retained in each position during the ejection of the dunnage.

Abstract: A fluid pathway assembly includes a needle insertion mechanism, a fluid conduit, and a fluid pathway connection. The fluid pathway assembly may further include a drug container to hold a drug fluid prior to initiation of the injection. The assembly may include a carrier disposed along at least a portion of the fluid pathway assembly, and/or a drug container. The fill-finish cartridge functions to retain the components of the fluid pathway assembly in a sterile condition, while allowing for easy integration of the fluid pathway assembly and the drug container into a standard fill-finish process. Methods of constructing a cartridge, filling a drug container included in a cartridge, and incorporating the same into a drug delivery device are disclosed.

Abstract: Devices work as both area lighting and ionizing radiation detectors. The lighting is adjustable in response to radiation detection, warning nearby users about radiation. Multiple devices can be plugged into electrical outlets throughout a plant or building to replace conventional lighting like lightbulbs or CFLs. Each device can transmit alerts to notify nearby users and transmit data to processors for aggregation and analysis. The data can be sent wirelessly, over fiber optic cable, as power line communications or otherwise. The data can be multiplexed along a single line. The devices may be in known locations or located based on an ID in the data. This data can be used to locate radiation sources and facilitate analysis and alerting at the location. Operators may respond to the radiation detection by issuing commands to the devices to change lighting output, adjust radiation detection parameters, and take corrective or ameliorative action in the facility.

Abstract: A resistance control system of an amusement attraction includes a support assembly having a base, a pivot joint, and a support beam extending between the base and the pivot joint. The resistance control system includes a spring plate coupled to the pivot joint of the support assembly, and includes at least one spring engaged with the spring plate. Additionally, the resistance control system includes an actuator plate positioned between the spring plate and the base of the support assembly, as well as at least one actuator coupled between the actuator plate and the base. The at least one actuator is configured to move and secure the actuator plate relative to the pivot joint to adjust a resistance to movement about the pivot joint.

Abstract: Disclosed are compositions of matter, cells, protocols and procedures useful for augmentation of one or more therapeutic activities of fibroblast cellular populations. In one embodiment fibroblasts are pretreated with growth factor-comprising composition(s), wherein the growth factor(s) may be cytokines, peptides, and/or proteins. In another embodiment fibroblasts are cultured with platelet rich plasma and/or derivatives from platelet rich plasma. In another embodiment, fibroblasts are cultured under hypoxic conditions prior to administration to an individual. The disclosure further provides means of assessment of fibroblast activity in vitro, including wound repair assay and cytokine production, for example.

Abstract: Disclosed are prodrugs of cytotoxic anthracyclines (such as doxorubicin) and other therapeutic agents that are selectively cleaved and activated by fibroblast activating protein (FAP). The prodrugs are useful for targeted delivery of cytotoxic and other agents to FAP-expressing tissues, including cancer (e.g., solid tumors). Also provided are pharmaceutical compounds comprising the prodrugs, as well as methods of using the prodrugs to treat a disorder characterized by FAP upregulation, e.g., cancer, fibrosis, and inflammation.