Abstract: The invention generally relates to methods of performing a capture reaction. In certain embodiments, the method involves obtaining a nucleic acid, fragmenting the nucleic acid, and capturing a target sequence on the nucleic acid fragment using a capture moiety, such as a molecular inversion probe.

Abstract: A system and a method for single sign-on voice authentication that provides access to multiple voice recognition and artificial intelligence platforms, to multiple devices and to multiple third party web service systems.

Abstract: The video playback technology disclosed herein gives fullscreen immersive experience to users when they watch videos on mobile devices used to watch the video. Specifically, an implementation of the technology disclosed herein gives a continuous all-time immersive experience by treating the screen of the mobile device as a window to watch a wide-angle video, and by keeping the video's relative angle to gravity unchanged while users rotate or tilt their mobile devices. In one implementation, the video also zooms in/out of the display during rotation of the smartphones, to give users a sense of getting closer/farther to the video. One or more implementations disclosed herein use inputs from gravity sensors including magnetic sensors, gyroscope, accelerometer, etc., to determine the amount of zooming in/out and shifting for the video in response to various movements, such as rotate, move, and tilt, of the video display device by the users.

Abstract: The present invention relates to the depolymerization of polymers and the recovery of the starting materials used for the production of the polymer. The present invention also relates to the depolymerization of polyethylene terephthalate (PET) and the recovery of terephthalic acid and ethylene glycol.

Abstract: The present invention provides a method for preparing levobunolol hydrochloride. In the present invention S-1-tert-butyl-epoxy methylamine is subjected to a substitution reaction with 5-hydroxy-1-tetralone, and acidified to obtain the target product levobunolol hydrochloride. The method provided by the present invention greatly improves the regioselectivity of the reaction, avoids the occurrence of side reactions, and effectively improves the yield and optical purity of levobunolol hydrochloride, with the yield being 87.3%, and the ee value being over 99%.

Abstract: The invention relates to assembly of sequence reads. The invention provides a method for identifying a mutation in a nucleic acid involving sequencing nucleic acid to generate a plurality of sequence reads. Reads are assembled to form a contig, which is aligned to a reference. Individual reads are aligned to the contig. Mutations are identified based on the alignments to the reference and to the contig.

Abstract: A system is disclosed for detecting and correlating percussive sounds with previously identified spectral signatures of a plurality of events so as to notify a user of an occurrence of a particular event. The system may include a sensor component which includes a piezoelectric transducer at a periphery of the sensor component for coupling with a surface and converting percussive sounds from the surface into an electrical signal. The sensor component may also include a local processor configured to produce a data signal based on the electrical signal, and a communication device for sending the data signal to a remote processor. The system may also include a remote processor configured to receive the data signal and compare the data signal to at least one reference signal, and send a notification to a user based at least in part on the data signal correlating to at least one reference signal.

Abstract: The present invention provides a method for preparing levobunolol hydrochloride. In the present invention S-1-tert-butyl-epoxy methylamine is subjected to a substitution reaction with 5-hydroxy-1-tetralone, and acidified to obtain the target product levobunolol hydrochloride. The method provided by the present invention greatly improves the regioselectivity of the reaction, avoids the occurrence of side reactions, and effectively improves the yield and optical purity of levobunolol hydrochloride, with the yield being 87.3%, and the ee value being over 99%.

Abstract: The invention generally relates to a communication and notification system and method thereof, and more particularly to a method and system for providing, tracking, sending reminders, and receiving communications/notifications in response to end-users in a variety of commercial market segments, e.g., medical, governmental compliance and criminal.

Abstract: An audio headset that provides a “chat” mode to temporarily adjusts audio to preset levels to emphasize ambient sound, and includes a beamformer to provide directional speech isolation. The headset may include active noise cancellation and/or passive noise isolation. When entering chat mode, three or more relative audio levels are individually adjusted to presets, allowing the wearer to hear ambient noise and their own isolated voice, while attenuating other audio sources. This user-configurable combination of levels temporarily adjust the mix of signals that will be output to a wearer via the stereo headphone speakers.

Abstract: The present invention relates to the depolymerization of polymers and the recovery of the starting materials used for the production of the polymer. The present invention also relates to the depolymerization of polyethylene terephthalate (PET) and the recovery of terephthalic acid and ethylene glycol.

Abstract: Functional jewelry is disclosed. A bracelet includes a plurality of light-emitting diodes (LEDs), a main control unit, and positional and situational sensors, typically including an accelerometer, as well as a decorative, interchangeable fascial layer. The bracelet may also include sensors such as capacitive touch sensors, a microphone, and a color sensor. A radio transceiver within the bracelet is adapted to implement a protocol such as BLUETOOTH® 4.0, and is adapted to allow the bracelet to communicate in peer-to-peer or master-slave mode. Two users can pair their bracelets in person, usually with a gestural trigger, for shared light displays, multi-player games, and other types of interactions. Larger groups can pair temporarily and contextually for multi-user displays and interactions, in an ad hoc network with distributed functions. Real-world interactions are communicated to a social network with profiles linked to the individual bracelets.

Abstract: Systems and methods for enabling gifting of a gift product on a merchant store front determine eligibility of an abstract product available for purchase on the merchant store front to be selected as a gift product, the abstract product representing a set of all available SKUs for a given product, a gift product representing a subset of all available SKUs for a given abstract product, and the subset including less than all available SKUs for the given abstract product and greater than one available SKU for the given abstract product; generate and place an embedded widget on the merchant store front to determine gift intent to initiate a gift transaction of the gift product; assign at least one representative SKU to represent the gift product; and mimic an orchestrated transaction between a user and the merchant store front prior to final selection of a specific SKU of the gift product.

Abstract: Systems and methods of providing enhanced product visualization on a graphical display include generating a visual frame having a first set of frame dimensions and comprising an inner border and an outer border; receiving a selection of a graphical object to be displayed at least within the outer border of the visual frame on the graphical display; identifying a set of object dimensions of the graphical object; determining an appropriate proportion between the set of frame dimensions and the set of object dimensions such that the graphical object is displayable at least within the outer border of the visual frame on the graphical display; manipulating the set of frame dimensions and/or the set of object dimensions such that the graphical object is displayable within the outer border of the visual frame; and displaying the graphical object at least within the outer border of the visual frame.

Abstract: A laundry holding snare device for holding multiple clothing items, particularly clothing items without full openings, is provided. The snare device can include two cord sections secured together at at least one end by an end stopper. The two cord sections can also be secured together at various locations along the length of the snare by intermediate stoppers in order to create several loading regions. Within the loading regions and attached to the cord sections can be a cordlock fastener that can be used to secure the clothing items between the cord sections at each loading region. The snare device can be configured for use as a stand-alone laundry device and the snare device can be configured for use with a laundry strap holder.

Abstract: A system architecture of a gift transaction system is disclosed. The gift transaction system can include a buyer interface module, a recipient interface module, a merchant backend interface module, a store front interface module, a curation module, a reminder module, an analytics module, or a media plug-in interface module. A method of operating the gift transaction system under the system architecture includes: providing an embedded widget on a website to determine gift intent to initiate a gift transaction by a buyer account for a recipient account; generating a gift buyer interface for a first client device to personalize a gift package including a gift item; generating a gift recipient interface for a second client device to customize the gift package; and communicating with a merchant backend system to complete the gift transaction to ship the gift package.

Abstract: A loop forming fastener including a ratchet and locking features that can be utilized to provide for a desired loop size. The loop forming fastener may include an elongate body portion having a first end and an opposite tail portion, with a head connected to the elongate body, the head defining an opening configured to receive the elongate body to form a loop. A ratchet may allow movement of the body through the opening in a first direction, but prevents movement in a second direction. The elongate body may include a stopper to maintain at least a minimum loop size. The head may include a locking mechanism to lock the elongate body, and thereby establish a desired size of the loop.

Abstract: A system architecture of a gift transaction system is disclosed. The gift transaction system can include a buyer interface module, a recipient interface module, a merchant backend interface module, a store front interface module, a curation module, a reminder module, an analytics module, or a media plug-in interface module. A method of operating the gift transaction system under the system architecture includes: providing an embedded widget on a website to determine gift intent to initiate a gift transaction by a buyer account for a recipient account; generating a gift buyer interface for a first client device to personalize a gift package including a gift item; generating a gift recipient interface for a second client device to customize the gift package; and communicating with a merchant backend system to complete the gift transaction to ship the gift package.

Abstract: Systems and methods for automatically generating a graphical interface include determining a counter value associated with a counter object and automatically determining one or more corresponding objects using the counter value. A subset of the one or more corresponding objects is determined and a graphical interface including the subset is generated. An updated counter value associated with the counter object is determined according to a modification and one or more updated corresponding objects are automatically determined using the updated counter value. An updated subset of the one or more updated corresponding objects is determined an updated graphical interface including the updated subset is generated and is transmitted, wherein when the updated graphical interface is received, the updated graphical interface facilitates a selection of an updated corresponding object from the updated subset.

Abstract: A message creator encodes message information into an original message. The message creator transmits the original message to a message recipient via a first medium. The message recipient receives the original message and decodes the original message to extract the encoded message information. The message recipient adds and/or modifies an attribute of the original message and re-encodes the message information in a modified message. The computer system transmits the modified message as if it were transmitted from the message creator to the message recipient. One attribute that the message recipient may modify is the message medium. As a result, the modified message may be transmitted via a different medium than the original message.