Patents Assigned to Madison
  • Recliner Apparatus
    Publication number: 20110049956
    Abstract: An adjustable recliner apparatus is provided having a seat member with a seat back portion pivotally attached to a seat bottom portion. The apparatus also includes a channel assembly. The channel assembly is made of a flange, a plurality of rollers connected to the flange and a channel configured to accommodate a plurality of rollers. The channel has a detent positioned to hold the seat back portion in substantially vertical position and this detent is sized to retard at least one of the plurality of rollers from rolling past the detent. The channel assembly is connected to the recliner frame and the flange is connected to the seat bottom portion of the seat member.
    Type: Application
    Filed: August 31, 2010
    Publication date: March 3, 2011
    Applicant: Madison Park, LLC
    Inventors: Ronnie C. Spivey, James W. Anton
  • System and method for identification and tracking of food items
    Patent number: 7899709
    Abstract: A food identification and tracking system includes a plurality of containers adapted to hold food items. An electronically-readable tag is affixed to each of the containers. The data stored on the tags may include information, such as an identification of a food item being held by the container, the ingredients of the food item, and/or the price of the food item, for example. The containers may be distributed by way of a conveyor system offering the food items in the containers for consumption. One or more sensors positioned relative to the conveyor may electronically read the data stored on a tag and cause the identification of the food item in a container to be shown on a display. When the data in each tag includes an indicator of the price of the food item, the cost of all the food item(s) consumed by a consumer may be calculated for payment.
    Type: Grant
    Filed: April 30, 2007
    Date of Patent: March 1, 2011
    Assignee: Madison Holdings, Inc.
    Inventors: James C. Allard, Stephen D. Rosen
  • FILTER ELEMENT FRAMES
    Publication number: 20110016837
    Abstract: A filter element comprises a top frame member, a bottom frame member and a pleated filter assembly received in respective channel sectioned formers comprised by said top and bottom frame members. The formers are integrally bonded with a polyurethane resin core formed in the formers. A mould may include a core member or projections which maintain air passages during moulding, and serve to locate the pleats of the filter element in relation to the air passages.
    Type: Application
    Filed: December 22, 2008
    Publication date: January 27, 2011
    Applicant: MADISON FILTER 981 LIMITED
    Inventors: Niels Fischer, Heiko Brinkmann
  • Membrane active polymers
    Patent number: 7871818
    Abstract: We describe a class of polymaleic anhydride polymers capable of disrupting cell membranes. Co-delivery of these polymers with biologically active compounds increases cellular cytoplasmic delivery of the compounds.
    Type: Grant
    Filed: January 27, 2004
    Date of Patent: January 18, 2011
    Assignee: Roche Madison Inc.
    Inventors: David B. Rozema, Darren Wakefield
  • UTILIZING LIFE INSURANCE TO BENEFIT A CHARITY
    Publication number: 20110010204
    Abstract: Funding a charity includes identifying an individual whose life represents an insurable interest to the charity, obtaining an insurance policy to cover the identified individual's life, funding premiums for the insurance policy from a funding source other than the insured individual and paying proceeds from the insurance policy for the benefit of the charity, pursuant to an agreement made approximately when the insurance policy was obtained.
    Type: Application
    Filed: September 20, 2010
    Publication date: January 13, 2011
    Applicant: National Madison Group, Inc.
    Inventor: Sam Radin
  • BELT SEAMS
    Publication number: 20100297386
    Abstract: A clipper seam for joining the ends of a belt, are connected by interdigitated staples which are looped about a pintle and provide barbs on their remote ends to penetrate into the material of the belt. Each end is covered by an edge strip of vinyl by radio frequency welding, and a flap is attached to one end on the low pressure side of the belt by a portion, and folded over to cover the seam on the low pressure side by means of a flap which extends beyond the seam area of the other end. A central area to each side of the seam is impregnated with polyurethane to resist abrasion which tends to concentrate in this area.
    Type: Application
    Filed: January 13, 2009
    Publication date: November 25, 2010
    Applicant: MADISON FILTER 981 LIMITED
    Inventor: Mark Stephen Coghlan
  • Reversible attachment of a membrane active polymer to a polynucleotide
    Patent number: 7816337
    Abstract: Described is a process for delivering a biologically active compound to a cell by reversibly linking the compound to a membrane active polymer. In particular, polymer-polynucleotide conjugates are described. Methods for reversibly modifying the polymers to decrease cellular toxicity and improve efficacy are provided.
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: October 19, 2010
    Assignee: Roche Madison Inc.
    Inventors: David B. Rozema, Darren Wakefield, Jon A Wolff, Kirk Ekena, James E. Hagstrom
  • Intravenous delivery of polynucleotides to cells in mammalian limb
    Patent number: 7803782
    Abstract: An intravenous delivery method is described that enables delivery of polynucleotides to extravascular cells of a mammalian limb. The method involves the injection of polynucleotides into a distal vein of a limb that is transiently occluded. Polynucleotide delivery is facilitated by rapid injection in sufficient volume to enable extravasation of the solution into surrounding tissue.
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: September 28, 2010
    Assignee: Roche Madison Inc.
    Inventors: James E. Hagstrom, Julia Hegge, Hans Herweijer, Jon A. Wolff
  • Process for delivering sirna to cardiac muscle tissue
    Patent number: 7781415
    Abstract: A process for delivering a polynucleotide to a cardiac tissue cell in a mammal is described, comprising introducing a composition consisting of a polynucleotide into a blood vessel and increasing permeability of the blood vessel to the polynucleotide. The polynucleotide can be a small interfering RNA or microRNA and inhibit gene expression in the cell.
    Type: Grant
    Filed: February 3, 2004
    Date of Patent: August 24, 2010
    Assignee: Roche Madison Inc.
    Inventors: Hans Herweijer, Julia Hegge, Jon A. Wolff, David L. Lewis
  • Filter element mounting apparatus
    Patent number: 7735659
    Abstract: A filter element, consisting of two pleated filter cloths has side frame members or strips and top and bottom frame members. The top and bottom edges of the cloths are encapsulated in the frame members, and the side edges of the filter cloths are clamped by the side frame members. This may be done by molding the frame members onto the cloth side edges, or by providing a slot in a tubular side frame member within which the side edges are held against the inner face of the slotted wall of the tube by a clamping member, such as a U-shaped strip, or by an indented part of the opposed wall.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: June 15, 2010
    Assignee: Madison Filter 981 Ltd.
    Inventor: Robert Haes
  • SURGICAL DEVICES AND RELATED METHODS THEREOF
    Publication number: 20100145330
    Abstract: The present invention relates to surgical devices and related methods of use. In particular, the present invention relates to surgical devices used for contacting and treating deeply seated areas of the brain.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 10, 2010
    Applicant: Madison Surgical Designs, LLC
    Inventor: Behnam Badie
  • Polyvinylethers for delivery of polynucleotides to mammalian cells
    Patent number: 7682626
    Abstract: A class of polymers for delivery of polynucleotides to cells in described. More specifically, amphiphilic polyvinylethers and compositions containing amphiphilic polyvinylethers are described.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: March 23, 2010
    Assignee: Roche Madison Inc.
    Inventors: David B. Rozema, Darren Wakefield
  • Devices and processes for distribution of genetic material to mammalian limb
    Patent number: 7642248
    Abstract: A process is described for the delivery of a therapeutic polynucleotide to limb muscle tissue suffering from or potentially suffering from Muscular Dystrophy. The polynucleotide is inserted into a mammalian limb vessel such as an artery. Delivery efficiency and distribution is enhanced by combining injection of a solution containing the polynucleotide with the use of an externally applied cuff.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: January 5, 2010
    Assignee: Roche Madison Inc
    Inventors: Vladimir G. Budker, Jon A. Wolff
  • METHODS FOR ENHANCED PRODUCTION OF BONE MORPHOGENETIC PROTEINS
    Publication number: 20090317867
    Abstract: Methods and processes for improved recombinant protein production are provided. The methods are useful for production of growth factors, particularly those of the TGF-? superfamily, including bone morphogenetic proteins (BMPs), such as BMP-2. Suitable host cells are cultured in media where iron is present at a concentration of at least 2.25 ?M and if pyridoxal is present, it makes up less than 55% of the molar concentration of vitamin B6 in the media.
    Type: Application
    Filed: April 16, 2009
    Publication date: December 24, 2009
    Applicant: Wyeth, Madison, New Jersey
    Inventors: Yen-Tung Luan, Wenge Wang, Gregg Nyberg, Jose Manuel Gomes, Denis Drapeau, Terry Cardoza
  • Delivery of molecules and complexes to mammalian cells in vivo
    Patent number: 7589059
    Abstract: Disclosed is a system for providing in vivo delivery of molecules or complexes to extravascular mammalian cells using an intravascular administration route. The molecules or complexes are inserted in an injection solution into a mammalian vasculature. Insertion of the injection solution at an appropriate rate transiently increases the volume of extravascular fluid in the tissue thereby facilitating delivery of the molecule to the cell.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: September 15, 2009
    Assignee: Roche Madison Inc.
    Inventors: Jon A. Wolff, Vladimir G. Budker, Hans Herweijer, James E. Hagstrom, Sean D. Monahan, Julia Hegge, Vladimir Subbotin
  • Nucleic acid injected into hepatic vein lumen
    Patent number: 7547683
    Abstract: Processes are described for obtaining high levels of gene expression in primates after injection of nucleic acid to the liver via the lumen of the hepatic vein. The described process results in high level of gene expression with transient increases in liver enzymes.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: June 16, 2009
    Assignee: Roche Madison, Inc.
    Inventors: Jon A. Wolff, Tatyana Budker, legal representative, Julia Hegge, James E. Hagstrom, Vladimir G. Budker
  • FLUID BED DRYER FILTERS
    Publication number: 20090145094
    Abstract: A fluidised bed filter comprises a drying pan, and a filter assembly having a membrane over the pan, and a plurality of openings in the membrane. A filter bag is secured to each aperture by means of a clamping ring attached to the rim of the respective aperture, and cooperating with a clamping band within the cuff of the bag. The material of the bag is clamped between the ring and the band. The ring is covered in a cloth strip, which is folded over to produce a flap, which is stitched between the layers of a double fabric forming the membrane. The band is retained in a tunnel formed by a fold in a double fabric forming the filter bag by stitching.
    Type: Application
    Filed: November 10, 2006
    Publication date: June 11, 2009
    Applicant: MADISON FILTER 981 LIMITED
    Inventors: Joseph Johnson, David Anthony Akerman
  • Compositions for Delivering Nucleic Acids to Cells
    Publication number: 20090124777
    Abstract: Cyclic amidinium containing compounds and their methods of preparation are described. Compositions containing these compounds facilitate delivery of biologically active polymers to cells in vitro and in vivo.
    Type: Application
    Filed: January 13, 2009
    Publication date: May 14, 2009
    Applicant: Roche Madison Inc.
    Inventors: Sean D. Monahan, Vladimir Trubetskoy
  • Polyampholytes for delivering polyions to a cell
    Patent number: 7524680
    Abstract: An polyampholyte is utilized in a condensed polynucleotide complex for purposes of nucleic acid delivery to a cell. The complex can be formed with an appropriate amount of positive and/or negative charge such that the resulting complex can be delivered to the extravascular space and may be further delivered to a cell.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: April 28, 2009
    Assignee: Roche Madison Inc.
    Inventors: Jon A. Wolff, James E. Hagstrom, Vladimir G. Budker, Vladimir S. Trubetskoy
  • Intravascular delivery of nucleic acid
    Patent number: 7507722
    Abstract: Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian blood vessel. Prior to insertion, subsequent to insertion, or concurrent with insertion the permeability of the vessel is increased using an exterior cuff thereby the genetic material is delivered to the parenchymal cell.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: March 24, 2009
    Assignee: Roche Madison Inc.
    Inventors: Jon A. Wolff, Vladimir G. Budker