Patents Assigned to Madison
  • Publication number: 20090074885
    Abstract: Described are drug formulations that increase regional delivery of the drugs to cells. Methods for reversibly increasing the hydrophobicity of a drug through hydrolytically labile attachment of a hydrophobic moiety and methods for delivering the modified drug to cells are described. Hydrophobic modification increases drug delivery, while lability minimizes entry of the drug into non-target cells.
    Type: Application
    Filed: October 29, 2008
    Publication date: March 19, 2009
    Applicant: Roche Madison Inc.
    Inventors: Sean D. Monahan, Vladimir Subbotin, Zane C. Neal, Vladimir G. Budker, Tatyana Budker
  • Patent number: 7501394
    Abstract: We describe compounds that bind to and are internalized by hepatocytes. Association of these compounds to other molecules or complexes can be used to target the molecules or complexes to hepatocytes in vivo or in vitro.
    Type: Grant
    Filed: January 20, 2006
    Date of Patent: March 10, 2009
    Assignee: Roche Madison Inc.
    Inventors: Alexander V. Sokoloff, So Wong, Jon A. Wolff, Sean D. Monahan, James Ludtke, Lori Higgs, Darren H. Wakefield, Magdolna G. Sebestyén
  • Patent number: 7498017
    Abstract: Cyclic amidinium containing compounds and their methods of preparation are described. Compositions containing these compounds facilitate delivery of biologically active polymers to cells in vitro and in vivo.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: March 3, 2009
    Assignee: Roche Madison Inc.
    Inventors: Sean D. Monahan, Vladimir Trubetskoy
  • Patent number: 7482160
    Abstract: A method of forming polymers in the presence of nucleic acid using template polymerization. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for forming nucleic acid binding polymers, for forming supramolecular complexes containing nucleic acid and polymer, and for forming an interpolyelectrolyte complex.
    Type: Grant
    Filed: December 30, 2005
    Date of Patent: January 27, 2009
    Assignee: Roche Madison Inc.
    Inventors: Sean D. Monahan, David B. Rozema, Vladimir Trubetskoy, Paul M. Slattum, Jon A. Wolff, Vladimir G. Budker, James E. Hagstrom, Lisa J. Hanson
  • Patent number: 7473419
    Abstract: Disclosed is a process for providing for expression of an exogenous nucleic acid in an extravascular parenchymal cell of a mammal. The nucleic acid is inserted into a vessel of a mammal and the permeability of the vessel is increased. Increasing permeability of the vessel allows delivery of the nucleic acid to an extravascular parenchymal cell.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: January 6, 2009
    Assignee: Roche Madison Inc.
    Inventors: Jon A. Wolff, James E. Hagstrom, Hans Herweijer, Vladimir G. Budker, Julia Hegge
  • Publication number: 20080314012
    Abstract: A ceramic filter element is formed from a flocculated slurry predominantly containing inorganic fibres, of 100-150 ?m length and 1-5 ?m thickness. The slurry also contains inorganic yarn in lengths of from 10 mm or greater, e.g. 10-150 mm and thickness 0.1-0.5 mm diameter. The slurry is formed in water with colloidal silica and starch added to flocculate the slurry. The flocculated slurry is then injected to a mould comprising an appropriately shaped mesh form, and water removed by vacuum, and the filter thus formed dried in an oven for 8-12 hours at 120° C. The addition of yarns, which may be glass or alumina mono or multifilament yarns, increases the shock resistance of the ceramic filter element produced.
    Type: Application
    Filed: October 27, 2006
    Publication date: December 25, 2008
    Applicant: MADISON FILTER 981 LIMITED
    Inventor: Richard Frazer Allen
  • Publication number: 20080290019
    Abstract: A scavenging filter includes a volume containing activated beads or fiber particles of a scavenging material housed in a removable housing in a cartridge filter body having an axial inlet extending to a space below a permeable false bottom, the fluid permeating upwards through the material, and cleaned liquor leaving via an annular space surrounding the chamber.
    Type: Application
    Filed: September 14, 2006
    Publication date: November 27, 2008
    Applicant: MADISON FILTER 981 LIMITED
    Inventor: Martin Moss
  • Publication number: 20080270324
    Abstract: A food identification and tracking system includes a plurality of containers adapted to hold food items. An electronically-readable tag is affixed to each of the containers. The data stored on the tags may include information, such as an identification of a food item being held by the container, the ingredients of the food item, and/or the price of the food item, for example. The containers may be distributed by way of a conveyor system offering the food items in the containers for consumption. One or more sensors positioned relative to the conveyor may electronically read the data stored on a tag and cause the identification of the food item in a container to be shown on a display. When the data in each tag includes an indicator of the price of the food item, the cost of all the food item(s) consumed by a consumer may be calculated for payment.
    Type: Application
    Filed: April 30, 2007
    Publication date: October 30, 2008
    Applicant: MADISON HOLDINGS, INC.
    Inventors: James C. Allard, Stephen D. Rosen
  • Patent number: 7381471
    Abstract: The present invention is directed to improved microdevices and methods of manufacturing such devices. More particularly the present invention is directed to the use of a compound having the general structure (formula (I)): wherein R is selected from the group consisting of C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C8 cycloalkyl, and C5-C6 aryl for bonding silica based substrates to plastic substrates or to other silica based substrates.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: June 3, 2008
    Assignees: University of Virginia Patent Foundation, James Madison University
    Inventors: Brian H. Augustine, James P. Landers, Jerome P. Ferrance, Joy M. Polefrone, W. Christopher Hughes
  • Publication number: 20080077652
    Abstract: Using an enhanced service contract to support the design, deployment, testing, and operation of an enterprise-wide service-oriented architecture. The enhanced service contract includes both static and dynamic parameters and may be contained in an electronic format to facilitate automating of certain design, deployment, testing, and operation functions. The enhanced service contract supports validating system requirements for a service, including developing test code used to test services. The enhanced service contract also supports performance testing during operations and supports allocating system costs and optimizing system resources.
    Type: Application
    Filed: September 6, 2006
    Publication date: March 27, 2008
    Applicant: Credit Suisse Securities (USA) LLC One Madison Avenue
    Inventors: Hugh Grant, Chris Swan
  • Patent number: 7326514
    Abstract: Resist compositions containing silicon, boron, or both silicon and boron may be used with ultra-violet lithography processes and extreme ultra-violet (EUV) lithography processes to increase the reactive ion etch resistance of the resist compositions, improve transmission of the resist materials, and to dope substrates.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: February 5, 2008
    Assignees: Cornell Research Foundation, Inc., University of Wisconsin-Madison
    Inventors: Junyan Dai, Christopher K. Ober, Lin Wang, Franco Cerrina, Paul Nealey
  • Publication number: 20080023868
    Abstract: Bamboo building material and process of manufacture therefor. The material includes a plurality of layers each formed of bamboo segments which have been dried and glue coated. The segments are substantially free of outer nodes and husk and inner membrane material prior to application of glue. The longitudinal axes of the segments in each layer are generally parallel to one another, each layer having segments oriented generally orthogonally with respect to the next adjacent layers thereto. The layers of segments being compressed and bonded together until the glue cures into a single integral structure.
    Type: Application
    Filed: February 13, 2007
    Publication date: January 31, 2008
    Applicants: Madison Insurance Trust, Newcore, L.P.
    Inventors: Leland Slaven, Morton A. Siegler
  • Publication number: 20080004630
    Abstract: The present invention relates to multiple-tract cannula devices and related methods of use. In certain embodiments, the present invention relates to multiple-tract cannula devices used for contacting and treating brain tissue (e.g., delivering pharmaceutical agents to brain tissue).
    Type: Application
    Filed: January 10, 2007
    Publication date: January 3, 2008
    Applicant: Madison Surgical Designs, LLC
    Inventor: Behnam Badie
  • Publication number: 20070270841
    Abstract: The present invention relates to implantable devices, and particularly implantable devices that may be positioned, for example, into the sphenoid sinus or sella turcica of a subject. In certain embodiments, the implantable devices comprise a center plate and a plurality of protruding arms extending from the center plate, both of which may be composed of bioresorbable material. In particular embodiments, the implantable devices are configured to help reconstruct the sellar floor after it has been damaged in order to prevent cerebrospinal fluid leaks.
    Type: Application
    Filed: January 31, 2007
    Publication date: November 22, 2007
    Applicant: Madison Surgical Designs, LLC
    Inventor: Behnam Badie
  • Publication number: 20070251872
    Abstract: A filter element, consisting of two pleated filter cloths has side frame members or strips and top and bottom frame members. The top and bottom edges of the cloths are encapsulated in the frame members, and the side edges of the filter cloths are clamped by the side frame members. This may be done by molding the frame members onto the cloth side edges, or by providing a slot in a tubular side frame member within which the side edges are held against the inner face of the slotted wall of the tube by a clamping member, such as a U-shaped strip, or by an indented part of the opposed wall.
    Type: Application
    Filed: November 5, 2004
    Publication date: November 1, 2007
    Applicant: MADISON FILTER 981 LTD.
    Inventor: Robert Haes
  • Publication number: 20070251873
    Abstract: Cloth retention apparatus for retaining the edges of a filter cloth comprises an edge strip having a bead, which can engage with a channel in a frame member, and be retained therein by a wedging member. The wedging member may be separate or attached to the bead, or incorporated therein. The wedging member may be a spring member.
    Type: Application
    Filed: November 25, 2004
    Publication date: November 1, 2007
    Applicant: MADISON FILTER 981 LTD.
    Inventors: Anthony Maquet, Richard Lydon
  • Publication number: 20070187025
    Abstract: Bamboo building material and process of manufacture therefor. The material includes a plurality of layers each formed of bamboo segments which have been dried and glue coated. The segments are substantially free of outer nodes and husk and inner membrane material prior to application of glue. The longitudinal axes of the segments in each layer are generally parallel to one another, each layer having segments oriented generally orthogonally with respect to the next adjacent layers thereto. The layers of segments being compressed and bonded together until the glue cures into a single integral structure.
    Type: Application
    Filed: July 27, 2006
    Publication date: August 16, 2007
    Applicants: Newcore, L.P., Madison Insurance Trust
    Inventors: Leland Slaven, Morton Siegler
  • Publication number: 20070156156
    Abstract: The present invention relates to surgical devices and related methods of use. In particular, the present invention relates to surgical devices used for contacting and treating deeply seated areas of the brain.
    Type: Application
    Filed: September 5, 2006
    Publication date: July 5, 2007
    Applicant: Madison Surgical Designs, LLC
    Inventor: Behnam Badie
  • Publication number: 20070143184
    Abstract: This disclosure provides a method of facilitating advertising research by providing a plurality of individual customer inputs, said plurality of individual customer inputs being obtained from searches by one or more customers using a customer response facilitation system, and characterized in that the final output of each search session includes at least one advertisement sought by the individual customer; computing the accuracy of the customer inputs relative to the advertiser's targeted advertisement or advertisements; and computing the precision of the customer inputs.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 21, 2007
    Applicant: MADISON AVENUE TOOLS, INC
    Inventor: Jeffrey Szmanda
  • Patent number: 7147745
    Abstract: Bamboo building material and process of manufacture therefor. The material includes a plurality of layers each formed of bamboo segments which have been dried and glue coated. The segments are substantially free of outer nodes and husk and inner membrane material prior to application of glue. The longitudinal axes of the segments in each layer are generally parallel to one another, each layer having segments oriented generally orthogonally with respect to the next adjacent layers thereto. The layers of segments being compressed and bonded together until the glue cures into a single integral structure.
    Type: Grant
    Filed: February 13, 2006
    Date of Patent: December 12, 2006
    Assignees: Newcore, L.P., Madison Insurance Trust
    Inventors: Leland Slaven, Jr., Morton A. Siegler