Patents Assigned to McGill University
  • Patent number: 11057053
    Abstract: Systems and methods of communicating using asymmetric polar codes are provided which overcome the codeword length constraints of systems and methods of communicating that use traditional polar codes. Used herein, asymmetric polar codes refers to a polarizing linear block code of any arbitrary length that is constructed by connecting together constituent polar codes of unequal length. Asymmetric polar codes may be known by other names. In comparison to conventional solutions for variable codeword length, asymmetric polar codes may provide more flexibility, improved performance, and/or reduced complexity of decoding, encoding, or code design. The system and method provide a flexible, universal, and well-defined coding scheme and to provide sound bit-error correction performance and low decoding latency (compared with current length-compatible methods which can be used with current hardware designs).
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: July 6, 2021
    Assignees: Huawei Technologies Co., Ltd., The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Warren Jeffrey Gross, Adam Christian Cavatassi, Thibaud Tonnellier, Yiqun Ge
  • Patent number: 11036232
    Abstract: A method and apparatus for generating adversarial scenarios and training an autonomous driving agent for an autonomous vehicle, using one or more sets of parameters, each set of parameters defining a respective driving scenario. A new set of parameters is generated by changing one or more parameters of one of the sets of parameters to define a new driving scenario, and performance of the autonomous driving agent is evaluated on the new driving scenario. The generating and evaluating is repeated until the autonomous driving agent fails to satisfy a predefined performance threshold for the new driving scenario. Each instance of changing the one or more parameters is based on a prior evaluated performance of the autonomous driving agent. The autonomous driving agent is trained to update a learned policy of the autonomous driving agent using at least one set of parameters, including the new set of parameters.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: June 15, 2021
    Assignees: HUAWEI TECHNOLOGIES CO., LTD, THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Florian Shkurti, Gregory Dudek, Yasasa Abeysirigoonawardena, Elmira Amirloo Abolfathi, Jun Luo
  • Patent number: 11014948
    Abstract: The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II): processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: May 25, 2021
    Assignees: The Royal Institution for the Advancement of Learning/McGill University, Hong Kong Polytechnic University
    Inventors: Masad J. Damha, Matthew Hassler, Tak-Hang Chan, Mallikarjuna Reddy Nandyala, Robert Alexander Donga
  • Publication number: 20210121277
    Abstract: A restraining device for an animal. A body having a base and two spaced-apart walls define a cavity to receive the animal. At least one pair of side restraining members is mounted to one of the walls of the body. Each restraining member is displaceable away from the wall and into the cavity to engage a side of the animal. An overhead restraining member is mounted to the body above the base. The overhead restraining member is displaceable toward and away from the base to engage the animal. A tightening mechanism is mounted to the body and has at least one rotatable rod. The first end of the rod has a rotatable handle to rotate the rod and the second end has a cam engaging one of the side restraining members. The handle rotates the cam and displaces the side restraining members into the cavity.
    Type: Application
    Filed: July 20, 2017
    Publication date: April 29, 2021
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Natasha RAJAH, Axel MATHIEU
  • Patent number: 10954194
    Abstract: The invention relates to a method of treating a subject who has cancer or a non-malignant tumor, the method comprising administering a therapeutically effective amount of a 18-20 member bi-polycyclic compound to the subject.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: March 23, 2021
    Assignees: Haro Pharmaceuticals Inc., The Royal Institution for the Advancement of Learning/ McGill University, Universite De Montreal
    Inventors: David Bettoun, Eduardo Martinez, James Gleason, Sylvie Mader, Shuo Xing
  • Patent number: 10942930
    Abstract: A system and method for graph-based publication/subscription are provided. A graph comprising nodes and edges is created, each node representative of a point of interest in an information domain, each edge linking a first node and a second node and representative of a relationship between a first and a second point of interest. A request to publish content on at least one selected node and/or at least one selected edge is received. A request to subscribe to a subset of nodes and/or a subset of edges is received from a subscriber. The subscription request is correlated with the publication request to determine whether the subset of nodes comprises the selected node and whether the subset of edges comprises the selected edge. The content is notified to the subscriber if the subset of nodes comprises the selected node and the subset of edges comprises the selected edge.
    Type: Grant
    Filed: December 5, 2016
    Date of Patent: March 9, 2021
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
    Inventors: Bettina Kemme, Joerg Kienzle, Cesar Canas Donero
  • Patent number: 10905749
    Abstract: The present disclosure relates to methods of treating or preventing a biofilm-related infection and methods of preventing and treating biofilm formation on indwelling medical devices, implants, and non-medical surfaces comprising administering at least one soluble microbial protein that is encoded by an exopolysaccharide biosynthetic operon or functional gene cluster, wherein the protein comprises a glycosyl hydrolase domain. The present disclosure further provides particular soluble glycosyl hydrolases and compositions thereof.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: February 2, 2021
    Assignees: The Hospital for Sick Children, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Lynne Howell, Perrin Baker, Noor Alnabelseya, Natalie Bamford, Dustin Little, Donald Sheppard, Brendan Snarr, Mark Jae Lee
  • Patent number: 10892379
    Abstract: GaN-based nanowire heterostructures have been intensively studied for applications in light emitting diodes (LEDs), lasers, solar cells and solar fuel devices. Surface charge properties play a dominant role on the device performance and have been addressed within the prior art by use of a relatively thick large bandgap AlGaN shell covering the surfaces of axial InGaN nanowire LED heterostructures has been explored and shown substantial promise in reducing surface recombination leading to improved carrier injection efficiency and output power. However, these lead to increased complexity in device design, growth and fabrication processes thereby reducing yield/performance and increasing costs for devices. Accordingly, there are taught self-organising InGaN/AlGaN core-shell quaternary nanowire heterostructures wherein the In-rich core and Al-rich shell spontaneously form during the growth process.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: January 12, 2021
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Zetian Mi, Songrui Zhao, Renjie Wang
  • Patent number: 10874685
    Abstract: The present disclosure provides a novel method for treating pancreatic cancer and pancreatitis in which a combination of a dopamine receptor antagonist (pimozide, haloperidol, and/or L-741,626), 2-deoxy-D-glucose and atorvastatin are used, optionally in combination with gemcitabine.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 29, 2020
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES ÖFFENTLICHEN RECHTS
    Inventors: Pouria Jandaghi, Yasser Riaz Alhosseini, Daniel Scott Auld, Veena Sangwan
  • Patent number: 10842634
    Abstract: An implant comprising a porous microstructure is disclosed which has an external surface, where at least a region of the external surface is formed of the porous microstructure. The microstructure is defined by at least one lattice of cells. Each cell has a predetermined cell topology and a plurality of edges. One or more of the edges of each cell connect to an adjacent cell along a corresponding edge thereof. Collectively, the cells have a periodic or aperiodic arrangement within the at least one lattice.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: November 24, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Damiano Pasini, Michael Tanzer, Sajad Khanoki Arabnejad, Burnett Johnston
  • Patent number: 10799363
    Abstract: A methodology integrating muitiscale analysis and design optimization to design a novel bone replacement implant made of a functionally graded cellular material that meets fatigue requirements imposed by cyclic loadings. The pore microarchitecture, described by interconnectivity, porosity, pore size as well as pore topology, is optimally designed for tissue regeneration and mechanical strength. The method can contribute to the development of a new generation of bone replacement implants with a graded cellular microstructure.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: October 13, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Damiano Pasini, Sajad Arabnejad Khanoki, Michael Tanzer
  • Publication number: 20200316185
    Abstract: A method of immunizing a human against infection by parasitic worms, comprising orally administering a live attenuated recombinant bacterium, expressing at least one antigen corresponding to a parasitic worm antigen; and a sterile injectable vaccine comprising the at least one antigen corresponding to a parasitic worm antigen. The method is effective against worms, including schistosomes.
    Type: Application
    Filed: March 6, 2020
    Publication date: October 8, 2020
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Brian J. Ward, Adam Hassan, Momar Ndao
  • Patent number: 10766851
    Abstract: It is provided a method of converting a diaryl ether source such as lignin and/or polyphenylene oxide (PPO) containing 4-O-5 linkages and an inorganic chemical such as ammonia into an organic compound, comprising reacting said diaryl ether source with the inorganic chemical in presence of a catalyst, preferably palladium, transforming the 4-O-5 linkages of said diaryl ether source into the organic compound. It is provided a palladium-catalyzed synthesis of aniline derivatives from 4-O-5 linkage lignin model compounds and cheap industrial inorganic chemical ammonia via dual C(Ar)—O bond cleavage.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: September 8, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY
    Inventors: Huiying Zeng, Chao-Jun Li, Dawei Cao
  • Patent number: 10767032
    Abstract: An auxetic metamaterial including a plurality of interconnected building blocks that are deformable between a collapsed position and an expanded position upon the application of a load. The building blocks are bistable, and define a stable state in both the collapsed position and the expanded position. In the stable state, the building blocks maintain the collapsed position or the expanded position, even after removal of the load applied on the building block.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 8, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Damiano Pasini, Ahmad Rafsanjani Abbasi
  • Patent number: 10752591
    Abstract: The invention relates to a method of inhibiting loss of muscle mass or muscle function in a subject in need thereof, or a method of treating miofibers ex vivo, the method comprising administering a therapeutically effective amount of a 18-20 member bi-polycyclic compound to the subject or to the miofibers.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: August 25, 2020
    Assignees: Haro Pharmaceuticals Inc., The Royal Institution for the Advancement of Learning/McGill University, Universite De Montreal
    Inventors: David Bettoun, Eduardo Martinez, James Gleason, Sylvie Mader, Shuo Xing
  • Patent number: 10739303
    Abstract: There is described a sensor for sensing a variable of a sample. The sensor generally has a graphene layer supported by a substrate; a parylene layer coating the graphene layer opposite the substrate; a sensing layer coating the parylene layer opposite the substrate, and being exposable to the sample; and electrical contacts at opposite ends of the graphene layer.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: August 11, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Thomas Szkopek, Ibrahim Fakih
  • Publication number: 20200238217
    Abstract: A technique for separating components of a microfluid, comprises a self-intersecting micro or nano-fluidic channel defining a cyclic path for circulating the fluid over a receiving surface of a fluid component separating member; and equipment for applying coordinated pressure to the channel at a plurality of pressure control areas along the cyclic path to circulate the fluid over the receiving surface, applying a pressure to encourage a desired transmission through the separating member, and a circulating pressure to remove surface obstructions on the separating member. The equipment preferably defines a peristaltic pump. Turbulent microfluidic flow appears to be produced.
    Type: Application
    Filed: December 23, 2019
    Publication date: July 30, 2020
    Applicants: National Research Council of Canada, The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Kebin LI, Teodor VERES, Tohid Fatanat DIDAR, Maryam TABRIZIAN
  • Patent number: 10725131
    Abstract: A topologically-protected traveling-wave amplifier includes resonators arranged in a two-dimensional array defining a periphery including a first edge. An output line is coupled to an output resonator disposed along the first edge spaced from an input resonator coupled to an output line. A synthetic gauge field generator associated with the resonators provides a topologically-protected edge state corresponding to propagation along the periphery in a propagation direction from the input resonator along the first edge to the output resonator. A parametric driving element creates pairs of photons in the edge state and amplifies a signal propagating along the first edge in the propagation direction. A signal incident from the input line propagates in the propagation direction along the first edge while being amplified and is detected at the output line as an amplified signal. A signal incident from the output line is attenuated before emerging at the input resonator.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: July 28, 2020
    Assignees: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY, FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERG
    Inventors: Aashish Clerk, Martin Houde, Florian Marquardt, Vittorio Peano Cavasola
  • Patent number: 10716707
    Abstract: Active dichoptic perceptual-learning tasks or dichoptic game play have been shown to significantly improve visual acuity of amblyopic children and adults. However, these dichoptic perceptual learning tasks are intensive and repetitive such that non-compliance is high. In contrast, the invention provides dichoptic perceptual learning in a manner that the user maintains its use and compliance is increased. Further, compliance becomes automatic if the user performs tasks in a normal manner and “forgets” that they are actually undergoing treatment as it is integrated with minimal disruption to their life and activities. Accordingly, a methodology exploiting complementary dichoptic stimulation is presented.
    Type: Grant
    Filed: August 27, 2015
    Date of Patent: July 21, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Robert F. Hess, Reza Farivar-Mohseni, Alexandre Reynaud
  • Patent number: 10711002
    Abstract: The present disclosure relates to novel compound of Formula I, or a pharmaceutically acceptable salt or solvate thereof; wherein R1, R2, Ra, Rb and Rc are as defined herein, pharmaceutical compositions containing same and methods for the treatment of cancer using same.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: July 14, 2020
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Moulay A. Alaoui-Jamali, Krikor Bijian, Dominik Wernic