Patents Assigned to Merck Patent GmbH
  • Patent number: 6960661
    Abstract: [7-(3-chloro-4-methoxybenzylamino)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-ylmethoxy]acetic acid, is disclosed, as well as a process for its preperation and intermediates in the process of preparing the same.
    Type: Grant
    Filed: December 29, 2001
    Date of Patent: November 1, 2005
    Assignee: Merck Patent GmbH
    Inventor: Hans-Michael Eggenweiler
  • Patent number: 6960599
    Abstract: The invention relates to heterocyclic aminoalkylpyridine derivatives of the formula I: where R1 is the radical of a heterocycle having 1 to 3 ring structures, where each ring structure is saturated, unsaturated or aromatic and optionally fused to other ring structures to give a fused ring system and the heterocycle has a total of 1 to 4 N, O and/or S atoms in the ring structures and is optionally monosubstituted, disubstituted or trisubstituted by one or more of the groups -A, —OR4, —N(R4)2, —NO2, —CN, Hal, —COOR4, —CON(R4)2, —COR4, ?O; R2 is a phenyl group which is optionally monosubstituted, disubstituted, trisubstituted, tetrasubstituted or pentasubstituted by one or more of the groups Hal, -A, —O-A, —NO2 or —CN, or is a thienyl group which is optionally monosubstituted or disubstituted by one or more of the groups Hal, -A, —O-A, -NO2, —CN or thienyl; R3 is H, -A, —CO-A, —C(R4)2R2, —C(R4)2-pyridinediyl-R2; R4 is H or -A; A is C1-C6-alkyl, where 1 to 7 hydrogen atoms are optionally replaced by fluor
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: November 1, 2005
    Assignee: Merck Patent GmbH
    Inventors: Dieter Dorsch, Henning Boettcher, Michael Arlt, Christoph Seyfried, Gerd Bartoszyk, Juergen Harting, Rudolf Gottschlich
  • Patent number: 6958152
    Abstract: Phospholipase C delta 5 (PLCD5) polypeptides and polynucleotides an methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing phospholipase C delta 5 (PLCD5) polypeptides and polynucleotides in diagnostic assays.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: October 25, 2005
    Assignee: Merck Patent GmbH
    Inventors: Klaus Dücker, Silke Brandt, Johannes Gleitz
  • Patent number: 6955837
    Abstract: Novel phenylcyclohexanes of the formula I in which n is 0 to 7, Q1 and Q2 are H, or one of these radicals is alternatively CH3, r is 0, 1, 2, 3, 4 or 5, A is trans-1,4-cyclohexylene, 1,4-phenylene, 3-fluoro-1,4-phenylene or a single bond, X is F, Cl, —CF3, —CN, —OCF3 or —OCHF2, and Y and Z are each, independently of one another, H or F, with the proviso that, in the case where A is a single bond, Q1=Q2=H and simultaneously X=CN, Y and/or Z are F.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: October 18, 2005
    Assignee: Merck Patent GmbH
    Inventors: Andreas Wachtler, Reinhard Hittich, Eike Poetsch, Herbert Plach, David Coates, Bernhard Rieger, Joachim Krause
  • Patent number: 6953611
    Abstract: An anisotropic polymer film comprising a polymeriZed chiral liquid crystal material with helically twisted structure and having areas with different helical twist sense is useful for decorative or security applications.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: October 11, 2005
    Assignee: Merck Patent GmbH
    Inventors: Robert Hammond-Smith, John Patrick, Alison Linda May
  • Patent number: 6953957
    Abstract: The invention generally relates to the use of poly-3,3?-dialkyl-2,2?:5?,2?-terthiophenes as charge transport materials or semiconductors in electrooptical, electronic or electroluminescent devices, and to charge transport and semiconducting components and devices comprising poly-3,3?-dialkyl-2,2?:5?,2?-terthiophenes.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: October 11, 2005
    Assignees: Merck Patent GmbH, Siemens AG
    Inventors: Iain McCulloch, Marcus Thompson, Mark Giles, Martin Heeney, Steven Tierney, Henning Rost
  • Patent number: 6953610
    Abstract: A liquid-crystalline medium based on a mixture of polar compounds of positive dielectric anisotropy, which contains: one or more compounds of the general formula I ?in which R, ?Y, Z and n are as defined in claim 1, one or more compounds of the following formulae IIa, IIb, IIc and IId and one or more compounds of the formula in which Ro, Xo, Y2 and r are as defined in claim 1.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: October 11, 2005
    Assignee: Merck Patent GmbH
    Inventors: Michael Heckmeier, Brigitte Schuler, Kazuaki Tarumi, Peer Kirsch, Volker Reiffenrath
  • Publication number: 20050220786
    Abstract: The invention relates to a lyophilised pharmaceutical preparation comprising an antibody against the endothelial growth factor receptor (EGF receptor). The preparation has increased storage stability, even at elevated temperatures, and, after reconstitution, can be used parenterally for the treatment of tumours.
    Type: Application
    Filed: November 25, 2002
    Publication date: October 6, 2005
    Applicant: Merck Patent GmbH
    Inventors: Hanns-Christian Mahler, Hans-Peter Zobel, Robert Mueller, Christiane Bachmann, Udo Haas, Ulrike Altenburger, Ludwig Krueger, Margarete Krueger
  • Patent number: 6951669
    Abstract: A liquid-crystalline medium having a mixture of polar compounds of positive dielectric anisotropy is described.
    Type: Grant
    Filed: July 2, 2004
    Date of Patent: October 4, 2005
    Assignee: Merck Patent GmbH
    Inventors: Michael Heckmeier, Brigitte Schuler, Kazuaki Tarumi, Peer Kirsch, Volker Reiffenrath
  • Patent number: 6946489
    Abstract: The invention relates to compounds of the formula I in which R1, R2, R3, R4 and X have the meaning indicated in the text. The compounds act as inhibitors of factors Xa and VIIa and can therefore be employed for the control and prevention of thromboembolic conditions such as thrombosis, myocardial infarct, arteriosclerosis, inflammation, apoplexy, angina pectoris, restenosis after angioplasty and intermittent claudication.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: September 20, 2005
    Assignee: Merck Patent GmbH
    Inventors: Horst Juraszyk, Dieter Dorsch, Werner Mederski, Christos Tsaklakidis, Christopher Bames, Johannes Gleitz
  • Publication number: 20050202538
    Abstract: The present invention provides Fc-erythropoietin (“Fc-EPO”) fusion proteins with improved pharmacokinetics. Nucleic acids, cells, and methods relating to the production and practice of the invention are also provided.
    Type: Application
    Filed: December 30, 2004
    Publication date: September 15, 2005
    Applicant: Merck Patent GmbH
    Inventors: Stephen Gillies, Jeffrey Way, Kin-Ming Lo
  • Patent number: 6943179
    Abstract: Novel compounds of the formula I in which X, Y, Z, R, R1, R2 and R3 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of tromboembolic diseases and for the treatment of tumors
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: September 13, 2005
    Assignee: Merck Patent GmbH
    Inventors: Werner Mederski, Bertram Cezanne, Dieter Dorsch, Christos Tsaklakidis, Johannes Gleitz, Christopher Barnes
  • Patent number: 6943263
    Abstract: The present invention relates to a novel process for the preparation of bis(trifluoromethyl)imido salts of the general formula (I): [Ma+]?[N(CF3)2]a??(I).
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: September 13, 2005
    Assignee: Merck Patent GmbH
    Inventors: Udo Heider, Michael Schmidt, Peter Sartori, Nikolai Ignatyev, Andrij Kucherina, Ludmila Zinovyeva
  • Patent number: 6943275
    Abstract: The invention relates to a process of preparing disubstituted 9-alkylidenefluorenes and structure analogous compounds, to novel compounds and intermediates prepared by this process, their use for the preparation of conjugated polymers and copolymers thereof, and to novel polymers and copolymers thereby prepared.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: September 13, 2005
    Assignee: Merck Patent GmbH
    Inventors: Martin Heeney, Steven Tierney, Mark Giles, Clare Bailey
  • Patent number: 6939479
    Abstract: Described herein are compounds of formula I wherein M1, M2 and M3 have the meanings recited in the disclosure, liquid crystalline mixtures and polymers containing them, and the use of the compounds of formula I, the liquid crystalline mixtures and the polymers containing them in optical and electrooptical devices like liquid crystal displays or projection systems, patterned films and optical elements like polarizers, retardation films, compensators, color filters, holographic elements or polarization beam splitters, for photoswitching, in anisotropic membranes for the permeation of gases or fluids, adhesives, synthetic resins with anisotropic mechanical properties, cosmetic or pharmaceutical compositions, UV absorbers and sunscreens, diagnostics or liquid crystal pigments, for decorative and security applications, in nonlinear optics, optical information storage or as dopants.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: September 6, 2005
    Assignee: Merck Patent GmbH
    Inventors: Louise Diane Farrand, Christopher Worrall, Owain Llyr Parri, Ian Victor Edward Hassall, Julian Frederick Samuel Vaughan-Spickers
  • Patent number: 6939527
    Abstract: The invention relates to a novel chromatographic process for the further purification of hydrogen peroxide solutions, giving high-purity solutions which can be employed in semiconductor technology under today's high purity requirements.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: September 6, 2005
    Assignee: Merck Patent GmbH
    Inventors: Dietmar Oeter, Claus Dusemund, Ewald Neumann, Klaus Freissler, Martin Hostalek
  • Patent number: 6933022
    Abstract: The invention relates to a liquid crystalline medium characterized by containing one or more compounds of general formula (I) and one or more compounds of formula (II), wherein R1, R2, R3, R4 and c have the meanings as cited in Claim No. 1.
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: August 23, 2005
    Assignee: Merck Patent GmbH
    Inventors: Melanie Klasen-Memmer, Dagmar Klement, Matthias Bremer
  • Patent number: 6929781
    Abstract: An interconnection support for plate-like microcomponents (1) has a support rail (2) which is attached to a support plate (3). An insertion slot (4) for the support rail (2) accommodates an insertion edge (5) of a plate-like microcomponent (1). Like connections (10, 10a), which can be connected to associated connections (11) in an outside (1a) of the plate-like microcomponent (1), are provided in at least one side wall (9) of the insertion slot (4) of the support rail (2).
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: August 16, 2005
    Assignee: Merck Patent GmbH
    Inventors: Michael Hohmann, Michael Schmelz, Hanns Wurziger, Norbert Schwesinger
  • Patent number: 6929832
    Abstract: AMLCDs containing a liquid-crystal medium which comprises a) at least one compound of the formula I and b) at least one compound of the formula II where the various parameters are as defined in the text, and to these liquid-crystal media and to their use in electro-optical displays.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: August 16, 2005
    Assignee: Merck Patent GmbH
    Inventors: Michael Heckmeier, Brigitte Schuler, Kazuaki Tarumi, Marcus Reuter
  • Patent number: 6929833
    Abstract: Liquid-crystalline mediums based on a mixture of polar compounds having positive dielectric aniostropy, characterized in that they comprise one or more compounds of the general formula I in which R, A1, Z1, Y and L are as defined herein, are suitable for use in MLC, TN and STN dispalys.
    Type: Grant
    Filed: April 4, 2003
    Date of Patent: August 16, 2005
    Assignee: Merck Patent GmbH
    Inventors: Kazuaki Tarumi, Brigitte Schuler, Eike Poetsch, Volker Reiffenrath, Yukiomi Tanaka