Patents Assigned to Meso Scale Technologies
  • Publication number: 20240159766
    Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
    Type: Application
    Filed: December 19, 2023
    Publication date: May 16, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Charles M. CLINTON, Eli N. GLEZER, Bandele JEFFREY-COKER, Sandor L. KOVACS, Sudeep M. KUMAR, George SIGAL, Carl STEVENS, Michael VOCK
  • Publication number: 20240151726
    Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a chemotherapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: January 16, 2024
    Publication date: May 9, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, Anu Mathew, Martin Stengelin, Mingyue Wang
  • Patent number: 11971359
    Abstract: We describe a detection module useful with an apparatus and/or system for conducting luminescence assays, and a kit, a system, an apparatus, and a method incorporating the detection module.
    Type: Grant
    Filed: November 16, 2020
    Date of Patent: April 30, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Jacob N. Wohlstadter
  • Patent number: 11971418
    Abstract: The present invention relates to methods of diagnosing glomerulonephritis (GN) in a patient, as well as methods of monitoring the progression of GN and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Grant
    Filed: February 8, 2021
    Date of Patent: April 30, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Galina Nikolenko
  • Patent number: 11967410
    Abstract: Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: April 23, 2024
    Assignees: Meso Scale Technologies, LLC, THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.
    Inventors: William F Blakely, Eli N. Glezer, John Kenten, Sudeep Kumar, Anu Mathew, Natalia I. Ossetrova, George Sigal
  • Patent number: 11960552
    Abstract: In examples, a method of controlling customer access to an assay system comprises (a) receiving a system identifier; (b) identifying said system identifier; and (c) utilizing information obtained from the system identifier to perform one or more operations selected from: (i) enabling full access to said system and/or a consumable used in said system; (ii) enabling partial access to said system and/or a consumable used in said system; or (iii) denying access to said system and/or a consumable used in said system.
    Type: Grant
    Filed: March 17, 2023
    Date of Patent: April 16, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
  • Patent number: 11940385
    Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: March 26, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Eli N. Glezer, Sharon West, George Sigal, Carl Stevens, Michael L. Vock
  • Publication number: 20240053364
    Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 27, 2023
    Publication date: February 15, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko
  • Patent number: 11892455
    Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
    Type: Grant
    Filed: October 1, 2020
    Date of Patent: February 6, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Sandor L. Kovacs, Sudeep M. Kumar, George Sigal, Carl Stevens, Michael Vock
  • Publication number: 20240027456
    Abstract: The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: October 4, 2023
    Publication date: January 25, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Anahit Aghvanyan, Eli N. Glezer, John Kenten, Sudeep Kumar, Galina Nikolenko, Martin Stengelin, Srikant Vaithilingam
  • Publication number: 20240027671
    Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.
    Type: Application
    Filed: September 20, 2023
    Publication date: January 25, 2024
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Cecilia Zimmerman, Jules VanDersarl
  • Publication number: 20230358764
    Abstract: The present invention relates to methods of diagnosing a liver disorder in a patient, as well as methods of monitoring the progression of a liver disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or regimen. The invention also relates to assay kits used in connection with the diagnostic methods described herein.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 9, 2023
    Applicant: Meso Scale Technologies, LLC.
    Inventor: George Sigal
  • Publication number: 20230229713
    Abstract: In examples, a method of controlling customer access to an assay system comprises (a) receiving a system identifier; (b) identifying said system identifier; and (c) utilizing information obtained from the system identifier to perform one or more operations selected from: (i) enabling full access to said system and/or a consumable used in said system; (ii) enabling partial access to said system and/or a consumable used in said system; or (iii) denying access to said system and/or a consumable used in said system.
    Type: Application
    Filed: March 17, 2023
    Publication date: July 20, 2023
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Xinri CONG, Jerome JACKSON, Carl STEVENS, Michael VOCK, Jacob N. WOHLSTADTER
  • Patent number: 11697840
    Abstract: The present invention is directed to improved methods for conducting immunoassays. The methods are designed to amplify signals in immunoassays and anchor immunoassay complexes employed therein.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: July 11, 2023
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eli N. Glezer, John Kenten
  • Patent number: 11630871
    Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such information in the conduct of an assay by an assay system.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: April 18, 2023
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Xinri Cong, Jerome Jackson, Carl Stevens, Michael Vock, Jacob N. Wohlstadter
  • Publication number: 20230070700
    Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.
    Type: Application
    Filed: November 14, 2022
    Publication date: March 9, 2023
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Cecilia Zimmerman, Jules VanDersarl
  • Publication number: 20230038393
    Abstract: Disclosed are methods for conducting diagnostic tests for the detection of the inflammatory bowel diseases, such as Crohn’s disease and ulcerative colitis. Also described are methods for monitoring a patient by administering tests of the present invention. Also described are methods for monitoring patient’s treatment by administering tests of the present invention. Also described are methods for evaluating the effectiveness of a drug or a drug candidate by administering tests of the present invention to samples from patients, animal models, and cell cultures treated with a drug or a drug candidate. Also disclosed are methods for determining the usefulness of analytes, e.g. cytokines, for acting as diagnostic and monitoring markers for inflammatory bowel disease in the various methods of the invention.
    Type: Application
    Filed: April 14, 2022
    Publication date: February 9, 2023
    Applicant: Meso Scale Technologies, LLC.
    Inventors: Jeff D. Debad, Eli N. Glezer, Sudeep M. Kumar
  • Patent number: D986435
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: May 16, 2023
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eric Jones, Jennifer Parker, Manish Kochar, Peter Bosco
  • Patent number: D1016325
    Type: Grant
    Filed: August 29, 2023
    Date of Patent: February 27, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Jacob N. Wohlstadter, Rodger Darin Osborne, Sandor Kovacs, Aaron Leimkuehler, Cecilia Zimmerman, Jules VanDersarl
  • Patent number: D1031072
    Type: Grant
    Filed: November 2, 2021
    Date of Patent: June 11, 2024
    Assignee: Meso Scale Technologies, LLC.
    Inventors: Eric Jones, Manish Kochar