Abstract: The application is directed to a device housing. The device housing includes a first light device, the first light device including a first electrical supply configured to provide an electrical signal to a first light emitting diode (LED), the first LED separated from a first surface of a diffuser film by a space, wherein the diffuser film includes a second surface, opposite the first surface, the second surface configured to contact a first light pipe.
Abstract: The present invention relates to methods of diagnosing an inflammatory disorder in a patient, as well as methods of monitoring the progression of an inflammatory disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Application
Filed:
August 18, 2022
Publication date:
December 8, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Jeffrey Debad, Eli N. Glezer, Sudeep Kumar
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Grant
Filed:
December 21, 2016
Date of Patent:
October 11, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen, The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Application
Filed:
February 9, 2022
Publication date:
September 22, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Simone Barbero, Eli N. Glezer, Anu Mathew
Abstract: The present disclosure relates to multiplexed assay formats configured to measure the level of a plurality of biomarkers that include a protein array for detecting autoreactive antibody levels against autoantigens.
Type:
Application
Filed:
November 22, 2021
Publication date:
September 8, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Eli N. Glezer, Mikayla Higgins, John Kenten, George Sigal
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
Type:
Application
Filed:
December 16, 2021
Publication date:
August 11, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Sudeep Kumar, George Sigal, Michael Tsionsky
Abstract: Described are assay methods, modules and kits useful in the detection, treatment and/or prevention of dementia and related conditions, including but not limited to Alzheimer's disease and mild cognitive disorders.
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
Type:
Application
Filed:
March 23, 2022
Publication date:
July 7, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Charles M. Clinton, Xinri Cong, Eli N. Glezer, Sudeep Kumar, Carl Stevens, Michael Vock, Jon S. Willoughby
Abstract: The present invention relates to methods of diagnosing a kidney disorder in a patient, as well as methods of monitoring the progression of a kidney disorder and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Application
Filed:
March 14, 2022
Publication date:
June 23, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Simone Barbero, Eli N. Glezer, Anu Mathew, Mingyue Wang
Abstract: We describe apparatuses, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of liquid samples in a clinical point of care setting.
Type:
Application
Filed:
December 28, 2021
Publication date:
June 23, 2022
Applicant:
Meso Scale Technologies, LLC.
Inventors:
Ian Chamberlin, Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Manish Kochar, Sandor Kovacs, DT Le, Aaron Leimkuehler, Greg Pinckney, Kristian Roth, George Sigal, Fei Yin
Abstract: The present invention relates to methods of diagnosing breast cancer in a patient, as well as methods of monitoring the progression of breast cancer and/or methods of monitoring a treatment protocol of a therapeutic agent or a therapeutic regimen. The invention also relates to assay methods used in connection with the diagnostic methods described herein.
Type:
Grant
Filed:
October 11, 2018
Date of Patent:
May 10, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Simone Barbero, Eli N. Glezer, Anu Mathew
Abstract: The present invention relates to methods, devices and systems for associating assay information with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system includes a reader adapted to read/erase/write information from/to an assay consumable identifier associated with the assay consumable. Various types of assay information are described, as well as methods of using such information in the conduct of an assay by an assay system.
Type:
Grant
Filed:
October 7, 2019
Date of Patent:
April 26, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Charles M. Clinton, Xinri Cong, Eli N. Glezer, Sudeep Kumar, Carl Stevens, Michael Vock, Jon S. Willoughby
Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.
Type:
Grant
Filed:
July 22, 2016
Date of Patent:
April 12, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Manish Kochar, Peter J. Bosco, Gary I. Krivoy, Louis W. Pang, Jennifer Parker, Jacob N. Wohlstadter, Michael L. Vock
Abstract: We describe apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation. They are particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, they may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.
Type:
Grant
Filed:
May 23, 2019
Date of Patent:
April 12, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Charles M. Clinton, Eli N. Glezer, Bandele Jeffrey-Coker, Sandor L. Kovacs, Sudeep M. Kumar, George Sigal, Carl Stevens, Michael Vock
Abstract: The invention relates to methods for conducting binding assays in an assay device that includes one or more storage and use zone. The storage zones of the assay device are configured to house one or more reagents used in an assay conducted in the use zone of the device.
Type:
Grant
Filed:
March 11, 2020
Date of Patent:
January 25, 2022
Assignee:
Meso Scale Technologies, LLC.
Inventors:
Sudeep Kumar, George Sigal, Michael Tsionsky