Abstract: Leachate remediation is performed by synergistic chemical oxidation and photocatalytic-oxidation enhancer system (SCOPES) of municipal landfill leachate to a level that is safe for disposal within regulatory guidelines. The physico-chemical (chemical, spectroscopic, elemental, microstructural and thermal) characteristics of the pre- and post-treated landfill leachate have been investigated to examine the utility of advanced oxidation (AO) processes such as SCOPES to decontaminate the municipal landfill leachate and/or toxic organic wastewater. The experimental results demonstrated successful lowering of chemical oxygen demand (COD) and UV-Vis absorbance for constituent contaminants in the leachate and/or wastewater solutions.

Abstract: A hierarchical porous honeycombed nickel oxide microsphere and a preparation method thereof are disclosed. The method includes mixing nickel sulfate hexahydrate, urea, water and glycerol, to obtain a mixed solution; subjecting the mixed solution to a hydrothermal reaction, to obtain a precursor; and calcining the precursor, to obtain the hierarchical porous honeycombed nickel oxide microspheres.

Abstract: The present invention discloses a device for pulverization and explosion suppression of low carbon gas hydrate (LCGH). A feeding chamber connects with a pulverizing chamber, and the chambers communicate through a feed port. A pulverizing air pipe and the feeding chamber communicate through a feeding air pipe; two ends of a venturi connect with an entrainment chamber and a disperser respectively; and a gas-solid separation membrane (GSSM) is disposed on a discharging port and used for preventing LCGH powder from entering the entrainment chamber from the pulverizing chamber. When an explosion is triggered, the GSSM is opened to make the LCGH powder enter the entrainment chamber. The device can store and pulverize the LCGH and spray LCGH powder to achieve combustion and explosion suppression.

Abstract: A differential microphone array includes a plurality of microphones situated on a substantially planar platform and a processing device, communicatively coupled to the plurality of microphones, to receive a plurality of electronic signals generated by the plurality of microphones responsive to a sound source and execute a minimum-norm beamformer to calculate an estimate of the sound source based on the plurality of electronic signals, wherein the minimum-norm beamformer is determined subject to a constraint that an approximation of a beampattern associated with the differential microphone array substantially matches a target beampattern.

Abstract: Aberrant cross talk between Notch ligand (e.g. Jag1) and Notch receptor (e.g. Notch1) has been implicated in tumorigenesis in the colon. Inhibition of Notch pathway is therefore an attractive approach for treating diseases with upregulated Jag1 e.g. colorectal cancer (CRC). Pan-notch inhibitors like gamma secretase inhibitors (GSIs) have been developed to inhibit Notch and its downstream events. However, severe gastrointestinal toxicity profiles impede the clinical development of GSIs. The present invention develops novel oligopeptides that specifically inhibit Jag1-Notch1 pathway without interfering DLL1-Notch1 or DLL4-Notch1, which demonstrates a clear advantage over pan-notch inhibitors.

Abstract: A hierarchical porous honeycombed nickel oxide microsphere and a preparation method thereof are disclosed. The method includes mixing nickel sulfate hexahydrate, urea, water and glycerol, to obtain a mixed solution; subjecting the mixed solution to a hydrothermal reaction, to obtain a precursor; and calcining the precursor, to obtain the hierarchical porous honeycombed nickel oxide microspheres.

Abstract: In the method for preparing single crystal superalloy test bars by using a Ni—W heterogeneous seed crystal, on the premise of ensuring that the single crystal superalloy has the required orientation, by reusing the seed crystal, it is achieved that the trouble caused by the need of preparing a new seed crystal when a single crystal superalloy is produced by the seed crystal method every time is avoided, and the production cost is significantly reduced. In the present disclosure, the formation of the stray grains in mushy zone could be avoided by using a Ni—W heterogeneous seed crystal without mushy zone and a built-in corundum tube.

Abstract: A yarn twisting method and device for a ring spinning machine is provided. The twisting method comprises the following steps: feeding three roving strands (1, 2, 3) into a back roller (8) of the ring spinning machine; after drafting, the three roving strands, three fiber strands (1, 2, 3) exiting from a nip point of a front roller (10), wherein a fiber strand (2) in the middle forms an angle with a plane formed by the other two fiber strands (1, 3), and thus the three fiber strands (1, 2, 3) form a multi-strand spinning triangle region having a three-dimensional spatial form; and in the multi-strand spinning triangle region, the three fiber strands (1, 2, 3) obtaining twist by means of a ring traveler of the ring spinning machine, and the twisted fiber strands (1 ,2, 3) are combined into a composite yarn (4) through a convergence point.

Abstract: A high-performance thin-film composite polyamide membrane upcycled from a substrate fouled with a biopolymer and a preparation method thereof are provided. The method includes fouling the substrate preferably with the biopolymer to obtain a composite of the substrate and a biopolymer foulant layer; then immersing the composite into a first solution formed by dissolving a polyamine monomer in water, followed by taking the composite out of the first solution and removing excess droplets from a surface of the composite; then immersing the composite treated in the previous step into a second solution formed by dissolving an acyl chloride monomer in n-hexane for interfacial polymerization to form a rejection layer on the surface of the composite; and after completion of the reaction, taking the composite out of the second solution, followed by drying and heat treatment, to obtain the target polyamide membrane.

Abstract: Disclosed is a polyvinylidene fluoride/ultra-high molecular weight polyethylene blend microporous membrane and preparation method thereof, which belongs to the field of microporous membrane. The blend microporous membrane has good hydrophobicity, mechanical properties and permeability. The preparation method includes: preparing a suspension by polyvinylidene fluoride, ultra-high molecular weight polyethylene, antioxidant and diluent; then feeding the obtained suspension into a twin-screw extruder, and the cast membrane gel extruded from the outlet is directly injected into a metal mold for injection molding; the mold temperature and the outlet temperature of the extruder are the same, and the cavity surface of the mold has micro-prism array structure; then cooling the mold in aqueous medium to obtain a nascent gel membrane; drying the obtained nascent gel membrane in a freeze dryer after removal of the diluents by extraction.

Abstract: A method and system for automatic assembly of a curved surface part are provided. First, a space coordinate system is established, and a first unit normal vector of the space coordinate system is determined. Then, coordinates of three measurement points on the surface of a curved surface part in the space coordinate system are acquired; and a second unit normal vector to the surface of the curved surface part are determined according to the coordinates of the measurement points. Finally, a rotation angle of the end effector is calculated according to the first unit normal vector and the second unit normal vector; and the end effector is adjusted according to the rotation angle, such that a third unit normal vector of the end effector after adjustment coincides with the second unit normal vector. The method and system enhance the automatic assembly quality of the curved surface part.

Abstract: A flexible electrocatalytic membrane for removing nitrate from water, a preparation method and use thereof are provided. The method of the present invention includes dropwise adding an aramid fiber solution into deionized water to prepare an aramid nanofiber sol, then reacting an ethanol solution containing 3,4-ethylenedioxythiophene and ferric nitrate with the aramid nanofiber sol to prepare a conductive aramid nanofiber sol, and finally dropwise adding MXene nanosheets ultrasonically pretreated by a tetramethylammonium hydroxide solution into the conductive aramid nanofiber sol to prepare the flexible electrocatalytic membrane. The prepared flexible electrocatalytic membrane possesses good mechanical strength and flexibility, and can not only effectively remove nitrate but also avoid failure of electrocatalytic materials due to surface fouling in the process of electrocatalytic reduction of nitrate, and thus has a long service life.

Abstract: A device for decomplexation and enhanced removal of copper based on self-induced Fenton-like reaction constructed by electrochemistry coupled with membrane separation is disclosed. The device includes a reactor, two electrocatalytic anodes capable of generating hydroxyl radicals, an electrocatalytic cathode membrane assembly, a direct current power supply, an aeration system, an inlet pipe and an outlet pipe. The device of the present invention has a simple construction. Using this device to treat industrial wastewater containing copper complexes under specific conditions allows the decomplexation and the removal of the industrial wastewater containing the copper complexes to be simultaneously realized at a low consumption and a high efficiency. The coupling of electrochemistry with membrane separation can be achieved to protect the cathode from being contaminated by pollutants in the sewage and prolong the service life of the electrode.

Abstract: Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(?)-EGCG]. Use of PRO-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.

Abstract: A differential microphone array includes a plurality of microphones situated on a substantially planar platform and a processing device, communicatively coupled to the plurality of microphones, to receive a plurality of electronic signals generated by the plurality of microphones responsive to a sound source and execute a minimum-norm beamformer to calculate an estimate of the sound source based on the plurality of electronic signals, wherein the minimum-norm beamformer is determined subject to a constraint that an approximation of a beampattern associated with the differential microphone array substantially matches a target beampattern.

Abstract: A method for analog-to-digital conversion with reconfigurable function mapping for acceleration of calculating an activation function of a neural network system includes determining, by a shared circuit, a set of voltage intervals using digital bits in a look-up table to define a shape of the activation function being mapped. The shared circuit determines a set of most significant bits (MSBs) for each voltage interval by storing additional bits in the look-up table corresponding to each voltage interval entry. Further, each of several per-neuron circuits determines whether its accumulated input voltage is in a received voltage interval, and if so, causing the set of MSBs to be stored. Each of the per-neuron circuits determines a set of least significant bits (LSBs) by performing a linear interpolation over the voltage interval. The set of MSBs and the set of LSBs are output as a result of the activation function with analog-to-digital conversion.

Abstract: A multi-level-architecture multi-fiber composite yarn includes a composite yarn having a first anisotropic expansion coefficient in an axial and/or radial direction, and a matrix material included with the yarn, wherein the matrix material has a second anisotropic expansion coefficient that is different from the first anisotropic expansion coefficient in at least one of the axial or radial directions. A method of fabricating a multi-level-architecture multi-fiber composite yarn includes infiltrating a composite yarn having a first anisotropic expansion coefficient in an axial and/or radial directions with a matrix material having a second anisotropic expansion coefficient different from the first anisotropic expansion coefficient in the axial or radial direction.

Abstract: The invention relates to the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. In another aspect, the invention relates to compounds of formula (II): processes for making these compounds, and the use thereof in the chemical synthesis of oligonucleotides, e.g., oligoribonucleotides. The invention also relates to methods of synthesis of oligomers, including but not limited to oligopeptides, oligosaccharides and oligonucleotides, particularly oligoribonucleotides and also oligodeoxyribonucleotides, in solution systems, and ionic tag linkers for use in methods provided herein.

Abstract: The present disclosure provides a method and system for analysing one or more edible oil samples. In an embodiment the disclosure provides for calibrating the matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-MS) data obtained for one or more edible oil samples to obtain calibrated spectral data; and comparing the calibrated spectral data derived from the one or more samples against a library of calibrated MALDI-MS spectra for a plurality of edible oil samples to determine the most likely composition of the one or more edible oil samples.

Abstract: Optimizations are provided for segmenting tissue objects included in an ultrasound image. Initially, raw pixel data is received. Here, each pixel corresponds to ultrasound information. This raw pixel data is processed through a first fully convolutional network to generate a first segmentation label map. This first map includes a first set of objects that have been segmented into a coarse segmentation class. Then, this first map is processed through a second fully convolutional network to generate a second segmentation label map. This second map is processed using the raw pixel data as a base reference. Further, this second map includes a second set of objects that have been segmented into a fine segmentation class. Then, a contour optimization algorithm is applied to at least one of the second set of objects in order to refine that object's contour boundary. Subsequently, that object is identified as corresponding to a lymph node.