Abstract: An apparatus for detecting RF signals in magnetic resonance testing procedure includes a multidirectional stretchable fabric and a flexible radio frequency (RF) coil. The flexible RF coil has a coil shape, and comprises conductive fiber stitched into the stretchable fabric in a plurality of repeating, non-linear stitch patterns. The plurality of stitch patterns collectively define the coil shape.
Type:
Grant
Filed:
May 12, 2020
Date of Patent:
May 23, 2023
Assignee:
Purdue Research Foundation
Inventors:
Joseph Vincent Rispoli, Jana M. Vincent
Abstract: Various implementations of a smart battery management system are provided. An example method includes identifying sensor data of a cell in a battery system; predicting, based on the sensor data, a failure event of the cell; and preventing the failure event by activating a control circuit connected to the cell.
Type:
Grant
Filed:
February 27, 2020
Date of Patent:
May 23, 2023
Assignee:
Purdue Research Foundation
Inventors:
Vikas Tomar, Thomas Edward Adams, Jonathan E. Alvarado, James Eric Dietz, Bing Li, Christian T. Neal
Abstract: A method of producing metallic sodium powders. The method includes immersing one or more solid pieces of sodium metal in an organic liquid containing a hydrocarbon oil. The solid piece (s) of sodium metal immersed in the hydrocarbon oil is (are) then subjected to ultrasonic irradiation, wherein the solid piece of sodium metal is fragmented to form sodium powder, resulting in a dispersion of the sodium powder in the organic liquid. The dispersed sodium powder is then separated from the organic liquid, resulting in metallic sodium powder. A method of presodiation of an anode in an electrochemical cell. The method includes adding sodium metal powders to the surface of the anode either as a dry powder or as a suspension of the sodium particles in an organic liquid. An anode in an electrochemical cell containing metallic sodium particles. An electrochemical cell comprising a presodiated anode.
Abstract: The present invention generally relates to peptides with no or substantially reduced fibrillation and their therapeutic uses, in particular to phosphorylated calcitonin peptides that have no measureable or substantially reduced fibrillation in an aqueous environment. Also described herein are pharmaceutical compositions of such compounds and methods for treating a patient suffering from pain, osteoporosis, Paget's disease, and/or hypercalcemia by administering therapeutically effective amounts of such compound alone, or together with other therapeutics, or in a pharmaceutical composition to a patient in need of relief.
Type:
Application
Filed:
March 26, 2021
Publication date:
May 18, 2023
Applicant:
Purdue Research Foundation
Inventors:
Elizabeth M. Topp, Karthik B. Chandrababu, Harshil K. Renawala
Abstract: Heat transfer devices and systems are provided for the rapid cooling of pulsed high-powered, high-flux devices using flash boiling. Such devices comprise at least two fluidly connected chambers and a heat exchanger in thermal communication with a heat source. A flash boiling event is actively triggered at a location close to the heat source by rapid depressurization of the chamber containing a multi-phase coolant. This boiling process allows for high heat transfer rates from the heat source into the chambers due to the latent heat of vaporization, which results in the rapid cooling of the heat source. A porous medium may also be positioned within a chamber of the device to enhance boiling nucleation and extended surface heat transfer. Methods of rapidly cooling pulsed heat sources are also provided using the devices and systems hereof.
Abstract: Aspects of the present disclosure involve systems, methods, and the like, for a fabrication of a particulate matter (PM) sensor that utilizes a capacitance sensor to detect sub-micrometer and nanoparticles in the respirable range of an environment. In one implementation, the capacitance sensor may comprise interdigitated electrodes between which a capacitance may be measured. PM deposited on the sensor may cause the capacitance between the electrodes to be altered and such a change in capacitance may be measured by the PM sensor. This measurement of the change in capacitance of the interdigitated capacitance sensor may therefore be correlated to the presence of sub-micrometer and nanoparticles in an environment. In one particular implementation, the PM sensor may further include a micro-heater circuit, a readout circuit, and an interface connecting the readout circuit to the micro-heater/capacitance sensor of the PM sensor.
Type:
Grant
Filed:
February 11, 2021
Date of Patent:
May 16, 2023
Assignees:
Colorado State University Research Foundation, Purdue Research Foundation
Inventors:
Su-Jung (Candace) Tsai, Doosan Back, David B. Janes
Abstract: A method of determining macrotexture of an object is presented which includes obtaining a plurality of stereo images from an object, generating a local coordinate system for each image, detecting one or more local keypoints each having a local coordinate, generating a global coordinate system based on a plurality of ground control points (GCPs) with apriori position knowledge of each of the plurality of GCPs, transforming the one or more local keypoints in each image to one or more global keypoints each having a global coordinate, generating a sparse point cloud based on the one or more global keypoints, reconstructing a 3D dense point cloud of the object based on neighboring pixels of each of the one or more local keypoints and calculating the global coordinates of each pixel of the 3D dense point cloud, and obtaining the macrotexture based on the reconstructed 3D dense point cloud of the object.
Abstract: An apparatus for providing an optimized amount of refrigerant to a refrigeration system includes three valves coupled with a fluid coupling, the first valve being coupled between the fluid coupling and an inlet of a refrigerant source, the second valve being coupled between the fluid coupling and an outlet of the refrigerant source, the third valve being coupled between the fluid coupling and the refrigeration system, the fluid coupling having a refrigerant chamber operable to store a volume of refrigerant to selectively provide the volume of refrigerant to the refrigeration system upon operation of the first, second, and third valves.
Type:
Grant
Filed:
November 12, 2020
Date of Patent:
May 9, 2023
Assignee:
Purdue Research Foundation
Inventors:
James Edward Braun, Eckhard Achim Groll, Davide Ziviani, Akash Patil, Changkuan Liang, Orkan Kurtulus
Abstract: Systems and methods for performing surgical procedures. Such a system includes a cannula having proximal and distal portions. At least one carriage unit is slidably mounted within the proximal portion of the cannula for translation in axial directions of the cannula, and a tool has a shaft that is coupled to the carriage unit and protrudes through a port at the distal portion of the cannula. The tool has a working element mounted on a portion of the shaft that protrudes from the cannula to perform tasks within the cavity. A translation mechanism is provided for translating the carriage unit and its tool in the axial directions of the cannula, and a rotation mechanism is provided for rotating the tool about an axis of its shaft and relative to the first carriage unit. Rotation and translation mechanisms of each carriage unit are preferably individually and independently controlled.
Type:
Grant
Filed:
December 16, 2019
Date of Patent:
May 9, 2023
Assignee:
Purdue Research Foundation
Inventors:
David John Cappelleri, Yang Ding, Benjamin Varughese Johnson
Abstract: An example system includes a feature extraction engine to identify features in a compressed image at a plurality of scales. The features include features corresponding to compression artifacts and features corresponding to image content to be upsampled. The feature extraction engine is to identify the features in the compressed image at a first scale based on noncontiguous pixels. The system also includes a reconstruction engine to refine the features corresponding to the image content to be upsampled and mitigate the features corresponding to the compression artifacts. The system includes an upsampling engine to generate an upsampled version of the compressed image based on the refined and mitigated features.
Type:
Application
Filed:
April 7, 2020
Publication date:
May 4, 2023
Applicants:
Hewlett-Packard Development Company, L.P., Purdue Research Foundation
Abstract: A method for identifying a source of florescence is disclosed which includes shining light on a subject at a first wavelength, causing emission of light at a second wavelength from the source of fluorescence, filtering out light at the first wavelength, capturing at least one 2 dimensional (2D) image of a subject having a plurality of pixels at the second wavelength, and establishing information about approximate location of a source of florescence within a tissue of the subject, selectively generating a 3D geometric model where the model is adapted to provide a model representation of the at least one 2D captured image, comparing the modeled at least one 2D captured image to the captured at least one 2D image and iteratively adjusting the model to minimize the difference, and outputting location and geometric configuration of the source of fluorescence within the tissue within the region of interest.
Type:
Grant
Filed:
August 28, 2019
Date of Patent:
April 25, 2023
Assignee:
Purdue Research Foundation
Inventors:
Brian Zahler Bentz, Kevin J. Webb, Dergan Lin
Abstract: The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate.
Abstract: This invention generally relates to methods useful for measuring heart rate, respiration conditions, and oxygen saturation and a wearable device that incorporate those methods with a computerized system supporting data collection, analysis, readout and sharing. Particularly this present invention relates to a wearable device, such as a wristwatch or ring, for real time measuring heart rate, respiration conditions, and oxygen saturation.
Type:
Grant
Filed:
October 16, 2020
Date of Patent:
April 25, 2023
Assignee:
Purdue Research Foundation
Inventors:
Jacqueline C Linnes, Benjamin David Walters, Orlando S Hoilett
Abstract: A method for imaging a sample, wherein the sample changes a polarization state of light as a function of position, wherein the method includes changing a polarization state of a purely polarized light of an incident light striking a micro-retarder array, thereby inducing a changed polarization state of the polarization state. The micro-retarder array is placed in a rear conjugate focal plane of a microscope. The method additionally includes projecting the changed polarization state of the polarization state into an object plane of the microscope containing the sample.
Type:
Grant
Filed:
May 18, 2021
Date of Patent:
April 25, 2023
Assignee:
Purdue Research Foundation
Inventors:
Garth Jason Simpson, James Ulcickas, Fengyuan Deng, Changqin Ding
Abstract: A system to monitor and control a lyophilization process using a wireless network is disclosed which includes one or more wireless pressure and gas temperature sensors adapted to provide pressure and gas temperature measurements of the ambient environment, a lyophilization chamber, wherein the one or more wireless pressure sensors are distributed in one or more lyophilization vial trays, a vacuum pump, adapted to change the pressure with the lyophilization chamber, a heat exchanger adapted to modify temperature within the lyophilization chamber, and a controller adapted to collect pressure and gas temperature data from the one or more wireless pressure and gas temperature sensors, calculate sublimation rate of a product to be lyophilized using the collected pressure and gas temperature data, and adjust one or both of pressure and temperature within the lyophilization chamber such that the calculated sublimation rate stays within a predetermined envelope.
Abstract: A batteryless, chipless, sensor is disclosed which includes a substrate, at least two conductive strips disposed on the substrate, a passivation layer encasing the substrate and the at least two conductive strips, wherein the conductive strips are adapted to respond to an interrogation signal from a reader having a first polarization, with a response signal at a second polarization different than the first polarization.
Type:
Grant
Filed:
October 26, 2021
Date of Patent:
April 25, 2023
Assignee:
Purdue Research Foundation
Inventors:
Sarath Gopalakrishnan, Jose Waimin, Rahim Rahimi, Nithin Raghunathan
Abstract: A method of optimizing probe placement in a turbomachine is disclosed which includes determining wavenumber (Wn) of N dominant wavelets generated by upstream and downstream stators and blade row interactions formed around an annulus, establishing a design matrix A utilized in developing flow properties around the annulus having a dimension of m×(2N+1), iteratively modifying probe positions placed around the annulus and determining a condition number of the design matrix A for each set of probe positions until a predetermined threshold is achieved for the condition number representing optimal probe position, wherein the condition number is defined as norm A·norm A+, wherein A+ represents inverse of A for a square matrix and a Moore-Penrose pseudoinverse of A for a rectangular matrix.
Abstract: The present disclosure relates to novel lymphoid-specific tyrosine phosphatase (LYP, encoded by the PTPN22 gene) inhibitors, and to methods of making and using the novel LYP inhibitors. Thus, the compounds according to the disclosure may be used for treating diseases or disorders associated with PTPN22 genetic polymorphism, including type 1 diabetes, rheumatoid arthritis, systemic lupus erythematosis, Graves' disease, Addison's disease, vitiligo, juvenile arthritis, Hashimoto thyroiditis, and other rarer diseases. Furthermore, these LYP inhibitors may be served for a novel class of cancer immunotherapy. The compounds can be injected or orally administered.