Abstract: Embodiments herein relate to breath analysis system. In an embodiment, a gas measurement device is included having a housing defining an interior volume. The housing can include a fluid ingress port, a fluid egress port, a bottom wall, and a circuit board disposed within the interior volume. The circuit board can include a first side and a second side, where the first side of the circuit board faces inward toward the interior volume. The circuit board can include a plurality of gas sensors disposed on the first side of the circuit board and a plurality of conductive pads disposed on the second side of the circuit board, wherein a plurality of electrical contacts contact the conductive pads when the circuit board is seated within the housing. Other embodiments are also included herein.

Abstract: Chemical sensors, devices and systems including the same, and related methods are disclosed. In an embodiment, a medical device is included having a graphene varactor including a graphene layer and a self-assembled monolayer disposed on an outer surface of the graphene layer through non-covalent interactions between the self-assembled monolayer and a ?-electron system of graphene. The self-assembled monolayer includes one or more pillarenes, substituted pillarenes, calixarenes, substituted calixarenes, peralkylated cyclodextrins, substituted peralkylated cyclodextrins, pyrenes, or substituted pyrenes, or derivatives of each. Other embodiments are also included.

Abstract: An electrical emulator system includes an emulator assembly comprising an emulator circuit board for emulating a component forming part of a modeled electrical system. The emulator circuit board includes an inverter mounted to the emulator circuit board, a set of input terminals electrically connected to the inverter, a set of output terminals electrically connected to the inverter and a processor electrically connected to the inverter and configured to control the inverter so as to provide emulation of a component of the modeled electrical system. A docking station includes a set of docking terminals for emulated line power. The docking station comprises guides to receive the emulator circuit board and align the set of input terminals and the set of output terminals to selected docking terminals of the set of docking terminals.

Abstract: Systems, devices, and techniques for allowing communication between two or more computing devices are described herein. For example, a method includes receiving, by a first computing device configured to operate in accordance with a first wireless protocol, one or more data packets via one or more signals output by a second computing device according to a second wireless protocol, where the first computing device is not configured to operate in accordance with the second wireless protocol. Additionally, or alternatively, a method includes receiving, by a first computing device configured to operate in accordance with a first wireless protocol, at least one signal including a data packet, wherein a payload of the data packet comprises an indication of a symbol defined in accordance with a second wireless protocol.

Abstract: A method for treating a cancer involving one or more translocations generating an oncogenic fusion transcription factor that requires p300/CBP for activity in an animal, comprising administering a compound of formula (I): or a pharmaceutically acceptable salt thereof to the animal.

Abstract: Genetically modified compositions, such as non-viral vectors and T cells, for treating cancer are disclosed. Also disclosed are the methods of making and using the genetically modified compositions in treating cancer.

Abstract: A varactor may include a gate electrode; a graphene layer; and a ferroelectric layer between the gate electrode and the graphene layer.

Abstract: The present invention provides in certain embodiments compositions comprising at least one CD200 inhibitor, and methods of reversing or modulating immune suppression in a patient having a disease or disorder arising from abnormal cell growth, function or behavior, which method comprises administering to a patient in need thereof a CD200 inhibitor composition.

Abstract: An apparatus for providing controlled jaw opening, including: a curved track attached to a first end of a housing; a first bite tray and a second bite tray coupled to the curved track, at least the second bite tray being slidably coupled to the curved track; and an adjustment mechanism disposed within the housing and coupled to the second bite tray, the adjustment mechanism including an extended handle disposed within the housing and extending from a second end of the housing opposite the first end, the extended handle being configured such that movement of the extended handle causes the second bite tray to move along the curved track.

Abstract: The invention provides a compound of formula (I): or a salt thereof wherein B, L, and X have any of the values defined in the specification, as well as compositions comprising a compound of formula (I) or a salt thereof. The compounds selectively degrade BRD4, and are useful as to treat cancer and inflammatory conditions.

Abstract: The present disclosure provides compositions and methods for treating Clostridium difficile infection (CDI) including primary and recurrent CDI. In particular, the compositions and methods described herein are capable of achieving a CDI clearance rate of at least 80% through a single oral dose of a pharmaceutical composition comprising a freeze-dried fecal microbiota preparation.

Abstract: Provided herein are methods and compositions for targeted delivery of cargo molecules, including, for example, gene editing reagents, RNA binding proteins, therapeutic agents, or other cargo via trogocytosis. In particular, provided herein are genetically modified donor cells as well as methods of using such genetically modified donor cells to deliver cargo of interest fused to a transmembrane receptor to a specific acceptor target cell.

Abstract: Disinfecting particulate material includes combining the particulate material with a photocatalyst to yield a mixture, irradiating the mixture for a length of time with pulses from a light source having broadband emission spectrum between 190 nm-1100 nm to yield an irradiated mixture, and separating the photocatalyst from the disinfected mixture to yield the disinfected particulate matter. Irradiating the mixture inactivates microorganisms in the mixture to yield a disinfected mixture. A system for disinfecting particulate material includes a pulsed light source having a broadband emission spectrum in a range between about 190 nm and about 1100 nm, a chamber defining a cavity optically coupled to the pulsed light source, a humidifier, a fan, and one or more sensors. The chamber includes a conveyor configured to accept the particulate material and arranged such that the pulses emitted by the pulsed light source irradiate the particulate material on the conveyor.

Abstract: CD19 variants, methods of identifying CD19 variants, and methods of using such CD19 variants, e.g., for treating cancer, are described.

Abstract: An embolic agent and a piezoelectric substance are mixed together. The mixture can be delivered to a tumor or other object by a non-invasive method. The embolic agent prevents movement of the piezoelectric substance from the target location. Subsequent impulses applied to the target location cause ablation of the surrounding area due to the piezoelectric effect of the particles, promoting highly accurate and precise ablation without the need for more invasive procedures.

Abstract: A vascular implant for an endoluminal stent or blood vessel, the stent or blood vessel defining a lumen for the passage of blood. The liner can comprise a flexible bladder arrangeable within the lumen, which can be fillable with a compressible fluid. The liner can define an inner lumen for the passage of blood. The liner and the fluid are conformable in response to a pulsatile pressure wave of the blood in the blood vessel such that the pressure within the blood vessel is reduced.

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.

Abstract: A fully connected ring oscillator circuit includes a plurality of first ring oscillator loops, a plurality of second ring oscillator loops, a plurality of ring oscillators and a plurality of coupled ring oscillators. Each first ring oscillator loop extends along a first axis. Each second ring oscillator loop extends along a second axis that is transverse to the first axis and intersects each of the first ring oscillator loops. Each ring oscillator includes one of the first ring oscillator loops connected to one of the second ring oscillator loops. Each coupled ring oscillator includes two of the ring oscillators that are connected to each other through a programmable weighted coupling block.

Abstract: A system and method for performing magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), or magnetic resonance spectroscopy imaging (MRSI) at multiple resonant frequencies using a coil system. The coil system includes at least one conductive loop and a capacitor forming a radiofrequency (RF) resonant antenna and a tuning-matching circuit electrically connected to the RF resonant antenna to operate at multiple resonant frequencies across a desired operational range. The coil system also includes two legs electrically connecting the tuning-matching circuit to the RF resonant antenna and having a length selected to generate at least two selected resonant frequencies with a selected frequency difference.

Abstract: The subject matter of this specification can be embodied in, among other things, a graphene plasmon resonator that includes a planar patterned layer having a collection of electrically conductive segments, and a collection of dielectric segments, each dielectric segment defined between a corresponding pair of the electrically conductive segments, a graphene layer substantially parallel to the planar patterned layer and overlapping the collection of electrically conductive segments, and a planar dielectric layer between the planar patterned layer and the graphene layer.