Abstract: A time of flight detector includes an electromagnetic radiation emitter configured to emit a beam of radiation. A first optical element receives the beam of radiation and generates a collimated beam of radiation. A second optical element defines a narrow imaging field of view sufficient to capture reflected electromagnetic radiation from the collimated beam. An electromagnetic radiation sensor then senses the captured reflected electromagnetic radiation from the collimated beam in the narrow imaging field of view. Further narrowing of the imaging field of view is accomplished by selective enabling a sub-array of photosensitive elements with the electromagnetic radiation sensor.

Abstract: A method comprising: mapping an image onto multiple level sets connected by multiple branches, wherein each of said level sets corresponds to a predefined range of values for an attribute of said image; associating multiple pixels of said image to said multiple level sets in accordance with the value of each pixel; identifying a source level set associated with a source pixel of said multiple pixels; for each of said multiple pixels, determining that a distance between said source pixel and one of said multiple pixels is within a predefined threshold, wherein said distance is calculated as a function of a first distance between said source level set and said level set associated with said one of said multiple pixels; in one embodiment, the determined distance is applied to an image processing application to produce a processed image, and the processed image is rendered on a rendering medium.

Abstract: Provided is a method of focusing particles. The method includes: providing a suspension of the particles in a suspending medium; and flowing the suspension along a channel, such that the flowing suspension occupies a certain volume that has at least one cross-sectional dimension smaller than 100 ?m. The suspending medium has such viscoelastic properties, that flowing the suspension in the channel directs at least some of the particles towards a focus region, enclosed in said certain volume.

Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain are provided. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Clq, and optionally activating Fc receptors, but that is significantly reduced for binding to the inhibitory Fc?RIIb receptor. Furthermore, methods and compositions are provided for promoting complement dependent cytotoxicity (CDC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or a different non-Fc binding domain.

Abstract: An apparatus for measuring information indicative of electromobility in a sample includes a light source for generating coherent light, a modulator that modulates the optical path length, particularly a reciprocatable modulator arranged for modulating a first part of the generated light, a sample cell for accommodating the measured sample for applying an electric field to the sample and for receiving a second part of the generated light for interaction with the sample in the electric field, a modulator monitor for monitoring the modulator by detecting interference between a first part of the light coming from the modulator and an unmodulated third part of the generated light, and a light detector arranged separately from the modulator monitor for detecting interference between a second part of light coming from the modulator and light received from the sample cell. The detected signal includes the information indicative of electromobility in the sample.

Abstract: Provided is a platform for entrapment within alumina sol-gel carriers of labile biologically active materials such as proteins, therapeutic enzymes, enzymes of industrial relevance, antigens, and small molecules for achieving successful and efficient protective storage, protection from harsh environmental conditions such as heat, pH and chemicals, delivery to site and subsequent treatment and/or vaccination against diseases against which the active agents are targeted.

Abstract: An optical navigation device, including a radiation source capable of producing a beam of radiation; a sensor for receiving an image; and an optical element for identifying movement of an object on a first surface to thereby enable a control action to be carried out. The optical element is such that a whole of the imaged area of the first surface is substantially covered by the object in normal use. The device is operable to receive from the object on the first surface an input describing a pattern, to compare the received pattern to a stored reference pattern and to perform a predetermined function if the received pattern and stored reference pattern are substantially similar. The pattern may be a continuous line, the device being operable to store the continuous line as a set of turning points in chronological order.

Abstract: A lift apparatus for lifting a patient comprises a sling bar (60) adapted to have a sling (110) secured thereto, a controller (138) and a status indicator (160) responsive to the controller for indicating the status of at least one parameter associated with the lift apparatus. The associated parameters comprise height, speed, sling securement state, sling compatibility, and fault state.

Abstract: A method and computing program for providing a user computing platform with a response to a query, the response comprising indications to one or more Universal Resource Identifier optionally with instructions on how to get the relevant information from there, and how to format the response. Thus a user computing platform receives information directly from a content provider, whose rights are not infringed by the query engine. If payment or other limitations are imposed by the content provider or by the user, they are handled between the user and the content provider, without intervention by the query engine.

Abstract: An array of image sensing elements is arranged in rows and columns. A readout circuit for each column includes a circuit configured to receive a column select signal. A memory stores data indicative of a voltage of an image sensing element which is being read. An analog to digital conversion circuit provides an output to the memory to control the storing of data. The output is dependent on the voltage of the image sensing element. Power control circuitry operates to disable, at least partially, the analog to digital conversion circuit when the column has not been selected.

Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.

Abstract: The present invention relates to means and methods for modifying the expression of a component in the carotenoid biosynthetic pathway to modify the production of carotenoid towards accumulation of at least one of phytoene, phytofluene, zeta carotene or combinations thereof. The present invention further relates to genetically altered organisms having elevated content of these carotenoids. The present invention further relates to genetically altered organisms having elevated content of these carotenoids, particularly in chromoplast-containing cells.

Abstract: A first oscillator generates a first frequency. A second oscillator generates a second frequency. A controller determines a difference between the first frequency and the second frequency and determines a non-ideal component of the first frequency in dependence on a temperature response of the first and second oscillators.

Abstract: An apparatus for processing a radio navigation signal. The apparatus has a first correlator correlating a first signal component with a first code, providing a first output, and having a carrier frequency and data. The apparatus also has a second correlator is configured to correlate a second signal component with a second code, providing a second output, and being different from the first code, the second signal component having the same carrier frequency as the first signal component and the same data as the first signal component. Each of real (I) and imaginary (Q) parts of the second output are delayed relative to respective parts of the first output such that the data on the second signal component is delayed with respect to the data on the first signal component, providing a delayed second output. The processor processes the outputs, their data being aligned to provide frequency information about the carrier.

Abstract: The present invention discloses a system and method for generating a beam of fast ions. The system comprising: a target substrate having a patterned surface, a pattern comprising nanoscale pattern features oriented substantially uniformly along a common axis; and; a beam unit adapted for receiving a high power coherent electromagnetic radiation beam and providing an electromagnetic radiation beam having a main pulse and a pre-pulse and focusing it onto said patterned surface of the target substrate to cause interaction between said radiation beam and said substrate enabling creation of fast ions.

Abstract: A light detection system which comprises an active region between a back contact layer and a front contact layer is disclosed. The active region comprises a quantum well structure having a quantum well between quantum barriers, wherein the quantum well comprises foreign atoms that induce an excited bound state at an energy level which is above an energy level characterizing the quantum barriers.

Abstract: A neuronal recording system featuring a large number of electrodes and a portable wireless front-end integrated circuit for signal processing for low-power spike detection and alignment. The system is configured as a Neuroprocessor and introduces hardware architectures for automatic spike detection and alignment algorithms. The Neuroprocessor can be placed next to the recording electrodes and provide for all stages of spike processing, stimulating neuronal tissues and wireless communications to a host computer. Some of the algorithms are based on principal component analysis (PCA). Others employ a novel Integral Transform. The algorithms execute autonomously, but require off-line training and setting of computational parameters. Pre-recorded neuronal signals evaluate the accuracy of the proposed algorithms and architectures: The recorded data are processed by a standard PCA spike sorting software algorithm, as well as by the several hardware algorithms, and the outcomes are compared.

Abstract: A sensor pixel detects a photon and outputs a first voltage proportional to a time of arrival of the detected photon. This voltage is converted to a multi-bit digital signal in the format of a thermometer code. A number of counter circuits, one counter circuit per bit of the multi-bit digital signal, are provided to accumulate the thermometer coded outputs. Each counter is configured to increment in response to an active logic state of the corresponding bit of the multi-bit digital signal. Accumulated count values in the counter circuits provide a timing histogram with respect to photon detection.

Abstract: Slings for rotation of individuals are disclosed herein. In various embodiments, a sling includes a central support section supporting at least a torso of the individual, a superior support section disposed along a first side of the central support section, an inferior support section disposed along a second side of the central support section opposing the superior support section, and straps extending from each lateral side of the central support section. The superior support section includes an anterior support flap and a posterior support flap, and at least a portion of the posterior support flap is separated from at least a portion of the anterior support flap. A central axis bisects the superior support section, the central support section, and the inferior support section such that the sling is foldable about the central axis, and the central axis acts as a fulcrum for rotating the individual.

Abstract: A person support device comprises a body support, a first support loop, and a second support loop. The body support is configured to support at least a portion of a person. The first support loop is coupled to the body support and extends there from a first distance. The second support loop is coupled to the body support and is overlappingly coupled along a portion of the first support loop. The second support loop extends a second distance from the body support.