Patents Assigned to Research Development
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Publication number: 20170027869Abstract: Provided are liposomes encapsulating mupirocin, with particular benefit for systemic therapeutically effective delivery. Also provided herein are pharmaceutical compositions including the liposomes and methods of using them. The liposomes include a lipid membrane and an intraliposomal compartment, the intraliposomal compartment encapsulating mupirocin, at least one cyclodextrin compound and a pH dependent ionizable anion, e.g. acetate.Type: ApplicationFiled: April 8, 2015Publication date: February 2, 2017Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Yechezkel BARENHOLZ, Amiram GOLDBLUM, Ahuva CERN
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Publication number: 20170027890Abstract: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.Type: ApplicationFiled: September 8, 2016Publication date: February 2, 2017Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hoffmann-La Roche Inc.Inventors: Uri BEN-DAVID, Nissim BENVENISTY, Payal ARORA, Qing-Fen GAN, Ralph J. GARIPPA
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Publication number: 20170031007Abstract: An electronic device includes a ranging light source and a reflected light detector. A logic circuit causes the ranging light source to emit ranging light at a target. Reflected light from the target is detected using the reflected light detector, with the reflected light being a portion of the ranging light that reflects from the target back toward the reflected light detector. An intensity of the reflected light is determined using the reflected light detector. A distance to the target is determined based upon time elapsed between activating the ranging light source and detecting the reflected ranging light. Reflectance of the target is calculated, based upon the intensity of the reflected light and the distance to the target.Type: ApplicationFiled: July 27, 2015Publication date: February 2, 2017Applicants: STMicroelectronics (Research & Development) Limited, STMicroelectronics, Inc.Inventors: Darin K. Winterton, Sam Lee
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Publication number: 20170027794Abstract: In the embodiments described herein, the scale assembly automatically determines if an accessory, such as a sling, is properly connected to a sling bar of the person lifting device and, if the accessory is not properly connected, the scale assembly provides a user with a visual and/or audible warning and, in some embodiments, may lock-out the actuation controls of the person lifting device to prevent the person lifting device from being used.Type: ApplicationFiled: July 19, 2016Publication date: February 2, 2017Applicant: Liko Research & Development ABInventors: Mattias Andersson, Andreas Bolin, Marica Demby, Peter Rydstrom, Douglas A. Seim
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Publication number: 20170031194Abstract: A polarized light source configured for use in display device and backlight unit is described. The polarized light source comprising: at least one optically active structure comprising a plurality of nanorods configured to emit light of one or more wavelengths in response to exciting pumping field, said plurality of nanorods comprising nanorods aligned with a predetermined alignment axis so as to produce a desired polarization direction of the emitted light; and a light directing assembly comprising one or more optical elements in optical path of light emitted from the light emitting structure, said light directing assembly being configured to enhance output of the emitted light from the emitting structure while substantially maintaining the polarization of the emitted light passing therethrough. Preferably, layers associated with the polarized light source are aligned with parallel principal axes.Type: ApplicationFiled: March 31, 2015Publication date: February 2, 2017Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Qlight Nanotech Ltd.Inventors: Uri BANIN, Ehud SHAVIV, Hagai ARBELL
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Publication number: 20170028302Abstract: A method for restricting the number of consequential interactions to further virtual objects having a relationship with a first virtual object, resulting from an interaction with said first virtual object. The method comprises: defining a maximum number of consequential interactions, counting consequential interactions, and stopping further interaction when the maximum number of consequential interactions is reached.Type: ApplicationFiled: October 13, 2016Publication date: February 2, 2017Applicant: Technion Research & Development Foundation LimitedInventors: Gershon ELBER, Orit SHAKED, Oded SHMUELI
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Publication number: 20170027796Abstract: Patient lift systems and lift accessories for the same are disclosed. In one example, a system may include a rail having a carriage support channel formed in the rail, the channel having a width, the rail has a working load rating; a carriage slidably disposed in the rail for relative movement to the rail, the carriage comprising a shaft having a length; and a lift unit coupled to the carriage and operable to raise and lower a lifting strap, wherein the lift unit has a working load rating; wherein the length of the shaft of the carriage is less than the width of the channel when the working load rating of the lift unit is equal to or less than the working load rating of the rail. In this manner, lift units that are incompatible with the working load rating of the rail cannot be connected with the rail.Type: ApplicationFiled: July 19, 2016Publication date: February 2, 2017Applicant: Liko Research & Development ABInventor: Philippe Kaikenger
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Patent number: 9557573Abstract: A light emitting device is presented. The device comprises an array of pixels and an electrode arrangement, wherein said array of pixels comprises pixels of first and second groups comprising first and second pluralities of light emitting nanorods aligned along first and second predetermined axes respectively, the axes being substantially perpendicular to each other, and the pixels of said array are associated with a plurality of electrode elements of said electrode arrangement thereby enabling modulation of optical emission of one or more pixels separately from one or more other pixels of said pixel array by controllable application of an electric field, the device being therefore configured and operable as an active pixel emitter.Type: GrantFiled: May 9, 2012Date of Patent: January 31, 2017Assignees: Merck Patent GmbH, Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd., Qlight Nanotech, Ltd.Inventors: Volker Hilarius, Nadja Velesco, Uri Banin, Hagai Arbell, Serge Velesco
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Patent number: 9555032Abstract: Methods for treating or preventing tauopathies and/or A? amyloidosis by modulating CRF receptor signaling. Accumulation of hyperphosphorlyated tau protein in the CNS may be reduced by administration of CRF-R1 selective antagonists and/or CRF-R2 selective agonists. For example, in some aspects, methods for preventing the onset of Alzheimer's disease by administration of CRF-R1 selective antagonist are provided.Type: GrantFiled: June 13, 2008Date of Patent: January 31, 2017Assignee: Research Development FoundationInventors: Robert A. Rissman, Kuo-Fen Lee, Wylie W. Vale, Paul E. Sawchenko
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Patent number: 9554988Abstract: Methods, compositions and products for preventing skin tumor formation or inhibiting the development of an existing skin tumor in a subject are described. The methods involve administering to the subject a composition containing an ? adrenergic receptor agonist, such as brimonidine.Type: GrantFiled: June 29, 2011Date of Patent: January 31, 2017Assignee: Galderma Research & DevelopmentInventors: Guy Bouvier, Matthew James Leoni, Michael Graeber
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Patent number: 9555238Abstract: Provided is a device for iontophoretic delivery of a drug to or into a tissue, including an arrangement that prevents operation of the device at a current density that is higher than a predetermined value, the arrangement including first means responsive to a first data item, indicative of the surface area through which the current is to pass, as to set the maximal current allowed at the surface area indicated by the data item. Also provided is a method for iontophorectivally administering drug to or into a tissue, including determining a maximal allowed level of current density and preventing application of current density above the maximal allowed level.Type: GrantFiled: January 15, 2014Date of Patent: January 31, 2017Assignees: Hadasit Medical Research Services & Development Limited, Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Abraham J. Domb, Joseph Frucht-Pery, Mervyn Shapiro
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Publication number: 20170020130Abstract: Composition and method for production of peroxycarboxylic acid solutions for various disinfection and cleaning compositions that utilizes non-equilibrium peroxycarboxylic acid. More specifically compositions comprise peracetic acid (PAA) and methods for making non-equilibrium PAA are provided. Frozen compositions useful as antimicrobial ice are provided.Type: ApplicationFiled: October 6, 2016Publication date: January 26, 2017Applicant: Eltron Research & Development, LLCInventors: Wayne E. Buschmann, Andrew S. Del Negro
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Publication number: 20170025915Abstract: Electric motor systems and methods may provide highly efficient operation. The electric motor systems and methods discussed herein provide an oil filled motor that is low speed and utilizes permanent magnets. The electric motor may utilize a large number of poles and fractional slot design. Further, in some embodiments, the electric motor systems and methods may be suitable for use downhole.Type: ApplicationFiled: October 3, 2016Publication date: January 26, 2017Applicant: Henry Research & Development, LLCInventors: Trevor Hardway, Michael Salerno, Ronald David Wallin
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Patent number: 9551712Abstract: The present invention provides sets of VOCs for breath analysis. Methods of use thereof in diagnosing, monitoring or prognosing breast cancer, head and neck cancer, prostate cancer or colon cancer are disclosed.Type: GrantFiled: January 6, 2011Date of Patent: January 24, 2017Assignee: Technion Research & Development Foundation Ltd.Inventors: Hossam Haick, Meggie Hakim
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Patent number: 9550299Abstract: A robotic link mechanism comprising a pair of base elements connected by a passive flexible joint, such that flexure of the joint changes the mutual orientation of the base elements. A pair of obliquely truncated cylinders are confined between the base elements such that the obliquely formed end surfaces of the cylinders can rotate in sliding contact with each other, and the other end of each cylinder can rotate in sliding contact with its associated base element. Driving motors are attached to the base elements, each one controlled to rotate the cylinder associated with that base element, such that rotation of at least one of the cylinders causes the base elements to undergo change in their mutual orientation. The mechanism thus has a backbone composed of the passive flexible joint, which is supported and actuated by the oblique truncated cylindrical structure that serves as an active exoskeleton.Type: GrantFiled: November 29, 2012Date of Patent: January 24, 2017Assignee: Technion Research & Development Foundation Ltd.Inventors: Alon Wolf, Oded Salomon
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Patent number: 9545514Abstract: A method and apparatus for making a connection with a part of a body to transfer an electromagnetic signal for a predetermined purpose, the apparatus including: a garment including one or more electrode capable of passing the signal to or from the part of the body; and a controller for controlling the nature of or processing the signal dependant on one or more parameters in order to vary the nature of the signal dependant on the purpose; wherein at least one parameter of the one or more parameters is stored on a data storage device included in the garment.Type: GrantFiled: May 30, 2007Date of Patent: January 17, 2017Assignee: BMR Research & Development LimitedInventors: Conor Minogue, Michel Las-Saulzais, Joseph M. Rochford
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Patent number: 9546359Abstract: Provided are methods for protein engineering, such as engineering proteases or kinases. The methods may utilize yeast display and/or ER sequestration of proteins or substrates. In some aspects, TEV proteases with altered substrate specificity, potency, and/or efficiency are provided.Type: GrantFiled: December 19, 2014Date of Patent: January 17, 2017Assignee: Research Development FoundationInventors: Brent Iverson, George Georgiou, Joseph M. Taft, Li Yi
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Patent number: 9548501Abstract: A supported catalyst is prepared by a process that includes establishing shell-removal conditions for a supported catalyst intermediate that includes capped nanoparticles of a catalyst material dispersed on a carbon support. The capped nanoparticles each include a platinum alloy core capped in an organic shell. The shell-removal conditions include an elevated temperature and an inert gas atmosphere that is substantially free of oxygen. The organic shell is removed from the platinum alloy core under the shell-removal conditions to limit thermal decomposition of the carbon support and thereby limit agglomeration of the catalyst material such that the supported catalyst includes an electrochemical surface area of at least 30 m2/gPt.Type: GrantFiled: December 17, 2009Date of Patent: January 17, 2017Assignees: The Research Foundation of State University Of New York Research Development Services, Binghamton University, Toyoata Jidosha Kabushiki Kaisha, Audi AGInventors: Chuan-Jian Zhong, Brigid Wanjala, Jin Luo, Peter N. Njoki, Rameshwori Loukrakpam, Minhua Shao, Lesia V. Protsailo, Tetsuo Kawamura
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Patent number: 9546210Abstract: Cripto, a developmental oncoprotein, antagonizes activin and TGF-b signaling by forming a complex with activin and TGF-b and their type II receptors. This complex precludes the formation of a functional activin/TGF-b•type II•type I complex, thereby blocking the signaling of activin and TGF-b. Cripto may be generally capable of blocking antiproliferative Smad2/3 signals and provides a novel mechanism of oncogenic action with multiple therapeutic implications. Inhibiting the formation of Cripto and activin/TGF-b complex may enhance antiproliferative effects of activin and TGF-b.Type: GrantFiled: September 21, 2010Date of Patent: January 17, 2017Assignee: Research Development FoundationInventors: Wylie Vale, Craig A. Harrison, Peter C. Gray
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Patent number: 9544065Abstract: A method of transmitting light is disclosed. The method comprises: transmitting a first light pulse into a medium to form in the medium a filamented region that is capable of guiding light, and transmitting a second light into the filamented region, wherein the second light is a pulsed light or continues wave light, and wherein the second light is transmitted at least 10 nanoseconds after the first light pulse.Type: GrantFiled: July 10, 2014Date of Patent: January 10, 2017Assignee: Technion Research & Development Foundation LimitedInventors: Mordechai Segev, Oren Cohen, Liad Levi
