Abstract: A hyperspectral method for detecting the present condition of an avian egg is disclosed in which a neural network algorithm is used to compare the spectrum of a test egg against a spectral library. The method can detect fertility with greater than 90% reliability on the day of laying and the gender of the chick with greater than 75% reliability on the 12th day after laying.

Abstract: Methods of expressing a recombinant polypeptide of interest are provided. Accordingly there is provided a method comprising providing a cell having been contacted with an agent which downregulates an expression of a tuberous sclerosis (TSC) protein or directly inhibits an activity of same; and contacting the cell with a polynucleotide encoding the recombinant polypeptide of interest. Also provided is a method comprising contacting a cell with an agent which downregulates expression of a tuberous sclerosis (TSC) protein or directly inhibits an activity of same; and a polynucleotide encoding the recombinant polypeptide of interest. Also provided are isolated cells, cell cultures and articles of manufacture for recombinant expression of a recombinant polypeptide of interest.

Abstract: Provided are new fatty acid derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, e.g., as agents for the treatment of obesity and related disorders, and for improving cognition.

Abstract: Provided are compositions including (3R, 4R, 6R)-stereoisomers of phenyl substituted pinenes having CB receptor agonist properties, methods of treating diseases or disorders with the pharmaceutical compositions, and processes for their preparation are also provided.

Abstract: A lighting system includes a light emitting diode array, and a time of flight ranging system. A logic circuit determines a distance to an object using the time of flight ranging system and controls the light emitting diode array based upon the distance to the object. A receptacle is coupled to the logic circuit, and sized and configured to fit within and be powered from a light bulb socket. In some applications, the logic circuit may activate the light emitting diode array when the object is less than a threshold distance away from the lighting system and deactivate the light emitting diode array when the object is greater than the threshold distance away from the lighting system. In further applications, the logic circuit may activate the light emitting diode array at a duty cycle that varies based upon the distance to the object.

Abstract: In some aspects, methods are provided for the treatment of mantle cell lymphoma (MCL) in a patient comprising administering a therapeutically relevant or effective amount of avicin D to the patient.

Abstract: A supporting instrument with a modular intramedullary nail includes a plurality of intramedullary nails and a coupling module. Each intramedullary nail is in a form of a long rod and has a coupling portion arranged between two ends of the intramedullary nail and an abutting surface along a longitudinal face of the intramedullary nail. The coupling module is mounted to the coupling portions of the plurality of intramedullary nails for the abutting surfaces of the plurality of intramedullary nails to abut against each other and for assembling the plurality of intramedullary nails.

Abstract: A supporting instrument with a modular intramedullary nail includes a plurality of intramedullary nails and a coupling module. Each intramedullary nail is in a form of a long rod and has a coupling portion arranged between two ends of the intramedullary nail and an abutting surface along a longitudinal face of the intramedullary nail. The coupling module is mounted to the coupling portions of the plurality of intramedullary nails for the abutting surfaces of the plurality of intramedullary nails to abut against each other and for assembling the plurality of intramedullary nails.

Abstract: A system and methods for controlling pulse parameters during transcranial magnetic stimulation are provided. Multiple coils are placed on external body parts, and are controlled using an external control unit coupled to a stimulator having fast switches. The timing of the switches, as well as other parameters within the stimulator, determine the pulse parameters, such as pulse shape. The variety of pulse shapes obtainable using such a system and methods provides controlled physiologic effects within an internal body organ.

Abstract: A module operates in a proximity detection mode and a gesture detection mode. The module includes an illumination source, radiation sensors and a controller. When in proximity detection mode, the illumination source emits radiation, the radiation sensors measure the radiation level, and the controller adjusts the measured radiation level to substantially cancel the contribution attributable to ambient radiation to determine the presence of a proximate object by. When in the gesture recognition mode, the level of radiation incident on the sensors is individually sampled, and the controller determines object movement by comparing the changes in the measured radiation levels over a plurality of the samples. Ambient radiation contribution is not removed from the sampled radiation levels during the gesture recognition mode.

Abstract: An autofocus method determines that a ranging device of a digital camera has failed in an attempt to provide a distance estimation. The ranging device provides one or more parameters indicating conditions related to the failure of the ranging device to provide the distance estimation. An autofocus sequence based on the one or more parameters is then performed.

Abstract: A camera module has a lens module mounted on a substrate. The image sensor is located in a cavity in the substrate and is connected to the substrate by a bridge member, the infra-red filter. The image sensor is attached to the infra-red filter by a ring of adhesive surrounding the imaging area of the image sensor. The adhesive attaching the image sensor to the infra-red filter comprises spacers. The infra-red filter is attached to the substrate by adhesive. The cavity may extend through the substrate. The image sensor is further connected to the substrate by a sheet member, which may be made of metal. The sheet member is affixed to the bottom of the substrate and covers the hole in the substrate formed by the extension of the cavity through the substrate. A method of assembly of the camera module includes: providing a substrate with a cavity; locating the image sensor in the cavity; connecting the infra-red filter to the image sensor and the substrate; and mounting the lens module on the substrate.

Abstract: The present invention is of methods of establishing and propagating human embryonic stem cell lines using feeder cells-free, xeno-free culture systems and stem cells which are capable of being maintained in an undifferentiated, pluripotent and proliferative state in culture which is free of xeno contaminants and feeder cells.

Abstract: This invention relates to a piggyback forklift truck and a method of operating same. The piggyback forklift truck comprises a motive power unit which includes an electric motor, a rechargeable battery pack powering the electric motor, a battery pack charging unit, a first electricity power supply connector in electrical communication with the battery pack charging unit, a DC/AC converter in electrical communication with the battery pack charging unit, and a second electricity power supply connector in electrical communication with the DC/AC converter, the second electricity power supply being arranged for reception of an electrical power take off feed from a carrying vehicle. In this way, the piggyback forklift truck can be charged by the mains supply when the carrying vehicle is not in transit and can be trickle charged while the carrying vehicle is in transit. This will maximize the operating time of the electrically powered piggyback forklift truck while it is making deliveries to customers.

Abstract: A movement system for use with an overhead patient lift system includes a motor. A drum is operatively coupled to the motor. The drum is configured to be selectively driven by the motor to rotate in one of a clockwise direction and a counter-clockwise direction. A lifting strap is coupled to the drum. The lifting strap is extendable and retractable with respect to a carriage of the overhead patient lifting system as the drum rotates. A manual release operatively coupled to the drum is actuatable to selectively disengage the drum from the motor to allow the lifting strap to be manually extended. Also disclosed is an overhead patient lift system including the movement system and a method for manually extending a lifting strap of an overhead patient lift system.

Abstract: The present disclosure provides pharmaceutical compositions and methods useful for modulating angiogenesis and for inhibiting metastasis, tumors, pulmonary alveolar proteinosis, and fibrosis in a mammalian tissue. Pharmaceutical compositions and methods include inhibitors of LOXL2 expression and activity, such as shRNA targeting LOXL2.

Abstract: A chemical formulation including: (a) at least one cement dispersant selected to disperse cementitious particles disposed in a water-based, flowable cementitious mixture, the cement dispersant including a polyphosphate; (b) a surfactant selected to reduce a surface tension of the mixture; (c) an accelerator selected to accelerate setting of the mixture; the formulation containing at least 200 grams of the polyphosphate per mole of an oxyalkalene functional group within the formulation.

Abstract: Well-defined, xeno-free culture media which comprise a TGF-beta isoform or the chimera formed between IL6 and the soluble IL6 receptor (IL6RIL6), which are capable of mainataining stem cells, and particularly, human embryonic stem cells, in an undifferentiated state are provided. Also provided are cell cultures comprising the culture media and the stem cells and methods of expanding and deriving embryonic stem cells in such well-defined, xeno-free culture media. In addition, the present invention provides methods of differentiating ESCs or EBs formed therefrom for the generation of lineage specific cells.

Abstract: The present disclosure relates to salts of the compound (I), polymorphic forms thereof, methods for preparation and use thereof, and pharmaceutical compositions thereof.

Abstract: A method for managing communication among a plurality of social network members. The method comprises defining a multi participant task, setting at least one forward rule limiting the distribution an invitation message for participating in the multi participant task, forwarding the invitation message to at least one addressee from a plurality of social network members, allowing the at least one addressee to forward the invitation message to at least one additional addressee from the plurality of social network members under the at least one forward rule, monitoring a plurality of feedbacks to the invitation message to determine whether the multi participant task is achieved, and updating a status of the multi participant task according to the determination.