Patents Assigned to Research
  • Patent number: 10462107
    Abstract: A computer-implemented system and method for analyzing data quality is provided. Attributes each associated with one or more elements are maintained. A request from a user is received for determining data quality of at least one attribute based on an interest vector having a listing of the elements of that attribute and a selection of elements of interest. Each element is encrypted. A condensed vector having the same listing of elements as the interest vector is populated with occurrence frequencies for each of the listed elements. The elements of the condensed vector are encrypted by computing an encrypted product of each element in the condensed vector and the corresponding element of the interest vector. An aggregate is determined based on the encrypted products of each element of the interest vector and the corresponding element of the condensed vector. The aggregate is provided as results of the data quality.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: October 29, 2019
    Assignee: Palo Alto Research Center Incorporated
    Inventors: Julien Freudiger, Shantanu Rane, Alejandro E. Brito, Ersin Uzun
  • Patent number: 10458901
    Abstract: An apparatus and method for simultaneously measuring, in an immersion microchannel environment, the characteristics of molecular junctions such as a low-molecular-weight biomaterial and the like and the refractive index of a buffer solution by using ellipsometry. Specifically, disclosed is an apparatus for simultaneously measuring, with high sensitivity, the change in refractive index of a buffer solution and the junction dynamic characteristics of a biomaterial by allowing polarized incident light to be received at a biomaterial adsorption layer, which is formed on a substrate such as a semiconductor and the like, so as to meet an anti-reflection condition of a P-wave by using a prism structure and a microchannel; and a measurement method using the same.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: October 29, 2019
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Hyun Mo Cho, Yong Jai Cho, Won Chegal
  • Patent number: 10456446
    Abstract: The present invention relates to a use of a human small leucine zipper protein in the osteogenesis procedure. More specifically, sLZIP increases the transcriptional activity of Runx2 and inhibits the transcriptional activity of PPAR?2, thereby increasing the osteoblast differentiation, so that sLZIP performs an important role in the osteogenesis procedure, and thus can be used as a marker for treating bone disease and developing new medicines.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: October 29, 2019
    Assignee: Korea University Research and Business Foundation
    Inventors: Je Sang Ko, Jeong-Han Kim
  • Patent number: 10457882
    Abstract: The present invention is directed to a method of producing a solid fuel which includes providing a bio-oil and thermally curing the bio-oil to form a carbonaceous solid. The present invention is also directed to a method of producing a solid fuel which includes providing a bio-oil; subjecting the bio-oil to an extraction procedure with an aqueous liquid to produce a concentrated pyrolytic sugar-containing extract and a water insoluble raffinate comprising a lignin-derived phenolic oil; and thermally curing the phenolic oil to form a carbonaceous solid.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 29, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Robert C. Brown, Marjorie Rover, Andrew J. Friend, Ryan G. Smith
  • Patent number: 10456520
    Abstract: A hospital bed rail attachment apparatus constructed of molded silicone or another form of elastomeric substance. An embodiment of the present disclosure includes an elongated member having a first appendage, a second appendage, and a central portion extending between the first appendage and the second appendage. The first appendage may include a first protrusion and a first receiving portion being configured to receive the first protrusion. The second appendage may include a second protrusion and a second receiving portion being configured to receive the second protrusion. Embodiments of the present disclosure may include a pair of elongated members being configured to be selectively coupled to a container at a first end and a hospital bed rail at a second end.
    Type: Grant
    Filed: February 18, 2018
    Date of Patent: October 29, 2019
    Assignee: Clinical Biotechnology Research Institute at RSFH
    Inventors: Lauren McNeill, Christopher Lienhop, Andrea H. Marshall, Krista Herndon
  • Patent number: 10456477
    Abstract: The present technology relates generally to oligolactic acid conjugates of paclitaxel, rapamycin, selumetinib, and other anticancer agents, micelle compositions containing such conjugates and methods of preparing and using such compositions to treat various cancers. Specifically, there are provided oligolactic acid conjugates wherein the oligolactic acid comprises 2 to 24 lactic acid subunits and is attached through an ester linkage to the oxygen of the 7-hydroxyl of the paclitaxel or paclitaxel derivative, the 40-hydroxyl of the rapamycin or rapamycin derivative, and the 2?-hydroxyl of the selumetinib or selumetinib derivative. Compositions comprising water and a micelle comprising a polylactic acid-containing polymer and the oligolactic acid conjugate may be readily prepared. Methods of inhibiting or killing cancer cells and treating paclitaxel, rapamycin, and/or selumetinib cancers are also provided.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: October 29, 2019
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Glen S. Kwon, Yu Tong Tam
  • Patent number: 10456407
    Abstract: The present disclosure relates to compositions comprising inhibitors of human histone methyltransferase EZH2 and one or more other therapeutic agents (such as tyrosine kinase inhibitors or VEGF/VEGFR inhibitors), particularly anticancer agents such as sunitinib, and methods of combination therapy for administering to subjects in need thereof for the treatment of cancer.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: October 29, 2019
    Assignees: Epizyme, Inc., Health Research, Inc.
    Inventors: Heike Keilhack, Roberto Pili
  • Patent number: 10457859
    Abstract: A proppant for use in hydraulic fracturing to stimulate a well is provided. The proppant is fly ash particles having a mean particle size (d50) of between 45 ?m and 150 ?m and a size distribution defined by (d10)?5 ?m and (d98)?250 ?m.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: October 29, 2019
    Assignee: UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
    Inventors: Thomas Lee Robl, Anne Elizabeth Oberlink
  • Patent number: 10457999
    Abstract: A method for recovery of platinum group metals from a spent catalyst is described. The method includes crushing the spent catalyst to obtain a catalyst particulate material including particles having a predetermined grain size. The method includes subjecting the catalyst particulate material to a chlorinating treatment in the reaction zone at a predetermined temperature for a predetermined time period by putting the catalyst particulate material in contact with the chlorine containing gas. The method also includes applying an electromagnetic field to the chlorine-containing gas in the reaction zone to provide ionization of chlorine; thereby to cause a chemical reaction between platinum group metals and chlorine ions and provide a volatile platinum group metal-containing chloride product in the reaction zone. Following this, the volatile platinum group metal-containing chloride product is cooled to convert the product into solid phase platinum group metal-containing materials.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: October 29, 2019
    Assignee: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Igor Lubomirsky, Valery Kaplan
  • Patent number: 10458979
    Abstract: The present invention relates to an artificial cell membrane system comprising at least one membrane protein carrier associated with at least one membrane protein, wherein the at least one membrane protein carrier comprises or consists of a polymeric vesicle or a polymeric planar structure, and a solid support freely suspended in a fluid medium, wherein the at least one membrane protein carrier is attached to a surface of the solid support. A method of forming the artificial cell membrane system, and use of the artificial cell membrane system as a reagent are also provided.
    Type: Grant
    Filed: August 29, 2012
    Date of Patent: October 29, 2019
    Assignee: Agency for Science, Technology and Research
    Inventors: Jinting Cheng, Madhavan Nallani
  • Patent number: 10458911
    Abstract: A method for screening an anticancer candidate is disclosed. The method includes immobilizing gold nanoparticles onto a substrate; binding a protein involved in carcinogenesis and metastasis to the immobilized gold nanoparticles, recording a spectrum of the protein conjugate, and analyzing the spectrum to obtain reference data; adding a candidate inhibiting the activity of the protein to the protein conjugate, recording a spectrum of the mixture, and analyzing the spectrum to obtain comparative data; and comparing the reference data with the comparative data to determine whether the candidate inhibits the activity of the protein. The method enables screening of a candidate inhibiting the activity of a protein involved in carcinogenesis and metastasis in an accurate and convenient manner.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 29, 2019
    Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sang Jun Sim, So Jin Song
  • Patent number: 10460978
    Abstract: A substrate support includes a conductive baseplate arranged to support a ceramic layer. The conductive baseplate includes a first cavity extending along an axis perpendicular to a horizontal plane defined by the conductive baseplate. A coupling assembly is arranged within the first cavity. The coupling assembly includes a gear configured to rotate about the axis. A pin arranged within the first cavity extends along the axis through the gear and into a second cavity below the conductive baseplate. Rotation of the gear causes the pin to move upward or downward relative to the conductive baseplate. The pin is retained within the second cavity when the gear is rotated to cause the pin to move downward into the second cavity.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: October 29, 2019
    Assignee: LAM RESEARCH CORPORATION
    Inventors: Fangli Hao, Yuehong Fu, Zhigang Chen
  • Patent number: 10460914
    Abstract: RF isolation for power circuitry includes one or more ferrite cages surrounding a pair of coils, one coil connected to power input, and the other coil connected to a load such as a heater. The ferrite cage provides universal isolation for the coils, avoiding the necessity of specially tuned filters or more complicated coil arrangements. A pair of dielectric discs support respective coils. In one aspect, the ferrite cage is constituted by ferrite pieces which fan out from a central portion of the dielectric discs and are connected at an outer periphery of the dielectric discs, and at the central portion of the dielectric discs. In one aspect, the fanned-out ferrite pieces comprises either manganese-zinc or magnesium-zinc ferrites, and the ferrite pieces connecting the fanned-out ferrite pieces comprise nickel-zinc ferrites.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: October 29, 2019
    Assignee: LAM RESEARCH CORPORATION
    Inventors: Hema Swaroop Mopidevi, John Pease, Thomas W. Anderson, Neil M. P. Benjamin
  • Patent number: 10460408
    Abstract: A computer-implemented patient information presentation method is disclosed. The method includes extracting, from records maintained for a patient under care in a healthcare facility, a subset of data points for that patient that are determined to represent data points of highest relevance to a subset of potential caregivers for the patient. The method also includes grouping the subset of data points into a plurality of groups based on a determined relatedness among data points in each of the plurality of groups, and generating a display for presentation to a caregiver that shows at least some of the subset of data points arranged in the groups.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: October 29, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Ognjen Gajic, Vitaly Herasevich, Brian W. Pickering
  • Patent number: 10458203
    Abstract: A method and apparatus for completing a well that includes a subsurface barrier valve utilizes an injection valve which includes a variable orifice insert. The injection valve includes a mechanism for sensing pressure cycles that are employed during various well completion operations including pressure testing. The mechanism includes an indexing sleeve which will disable pressure functionality. Once this occurs, pressure cycling to open the barrier valve can proceed. Once the barrier valve opens, flow alone controls the injection valve during normal operations.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: October 29, 2019
    Assignee: Tejas Research & Engineering, LLC
    Inventors: Jason C. Mailand, Thomas G. Hill, Jr.
  • Patent number: 10462489
    Abstract: There are provided an image processing device and a processing method thereof. The image processing method includes obtaining an interference signal using a sample beam and a reference beam, transforming the interference signal by using a numerical signal processing method or an intensity mixing method to generate a transformed interference signal, and obtaining a three-dimensional (3D) phase image by using the interference signal and the transformed interference signal.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: October 29, 2019
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Gi Hyeon Min, Nack Woo Kim, Mun Seob Lee, Byung-Tak Lee, Young Sun Kim
  • Patent number: 10458037
    Abstract: An exemplary embodiment of the present invention provides a method for anti-wetting metallic surfaces. A metallic object is introduced to an electrochemical solution. A cathode is introduced to the electrochemical solution, and an anode is attached to the metallic object. An electric potential between the cathode and anode is applied, such that selective electrochemical etching of the surface of the metallic object occurs. The selective etching etches grain boundaries at the surface of the metallic object, and the grain boundaries define grain faces.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: October 29, 2019
    Assignee: Georgia Tech Research Corporation
    Inventors: Won Tae Choi, Laurens Victor Breedveld, Dennis W. Hess, Kkochnim Oh, Preet M. Singh
  • Patent number: 10456480
    Abstract: This document provides methods and materials related to treating glaucoma, ocular hypertension, cardiovascular diseases, and renal diseases. For example, this document provides isolated nucleic acid molecules and viral vectors (e.g., lentiviral vectors) containing isolated nucleic acid molecules. Methods for reducing intraocular pressure as well as symptoms and progression of cardiovascular and renal diseases also are provided.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: October 29, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Eric M. Poeschla, Roman A. Barraza
  • Patent number: 10457707
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: October 29, 2019
    Assignee: St. Jude Children's Research Hospital
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Patent number: D865211
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: October 29, 2019
    Assignee: United Kingdom Research and Innovation
    Inventors: Minmin Yu, Adam Fowle