Abstract: The present invention relates to methods and compositions for determination of and uses of specific methylation patterns indicative of adenoma and carcinoma. In particular, the invention relates to analysis of defined CpG loci that are coordinately methylated in DNAs from cancer and adenoma samples, methods for identifying coordinately methylated loci, and methods of using analysis of coordinately methylated loci in one or more marker regions in the design of assays for adenoma and cancer.

Abstract: A resuscitation chamber apparatus for administering hyperbaric oxygen to a patient. More particularly, the present invention relates to a hyperbaric oxygen compatible critical care chamber apparatus preferably for use in emergency departments and/or prehospital ambulance management of patients. In a preferred embodiment of the present invention, the apparatus is a resuscitation monoplace hyperbaric chamber preferably used in critical care management of acutely ill or injured patients in prehospital emergency medical services (EMS) settings or in hospital emergency departments. The apparatus preferably allows a critical care shock or arrested patient to be pressurized preferably without compromise for application of best medical equipment, medications and human resuscitating intervention.

Abstract: The invention pertains to methods for monitoring the operational status of a home automation system through extrinsic visual and audible means. Initial training periods involve capturing image and audio data representative of nominal operation, which is then processed to identify operational indicators. Unsupervised machine learning models are trained with these indicators to construct a model of normalcy and identify expectation violations in the system's operational pattern. After meeting specific stopping criteria, real-time monitoring is initiated. When an expectation violation is detected, contrastive collages or sequences are generated comprising nominal and anomalous data. These are then transmitted to an end user, effectively conveying the context of the detected anomalies. Further features include providing deep links to smartphone applications for home automation configuration and the use of auditory scene analysis techniques.

Abstract: Methods, apparatus and systems for wireless motion recognition are described. In one example, a described system comprises: a transmitter configured for transmitting a first wireless signal through a wireless multipath channel of a venue; a receiver configured for receiving a second wireless signal through the wireless multipath channel; and a processor. The second wireless signal differs from the first wireless signal due to the wireless multipath channel that is impacted by a motion of an object in the venue. The processor is configured for: obtaining a time series of channel information (TSCI) of the wireless multipath channel based on the second wireless signal, tracking the motion of the object based on the TSCI to generate a gesture trajectory of the object, and determining a gesture shape based on the gesture trajectory and a plurality of pre-determined gesture shapes.

Abstract: A vehicle door positioning holder includes a hydraulic cylinder connected to the door and a vehicle chassis, and a brake hydraulically connected in a loop. The cylinder pushes hydraulic fluid in the loop when the door is moved. The brake includes first and second chambers hydraulically connected to the loop and a third chamber connected in the loop at respective ends to the first and second chambers. The brake has a ball element in the third chamber when the hydraulic fluid is still, moved towards the first chamber as the hydraulic fluid flows in a first direction, and moved towards the second chamber as the hydraulic fluid flows in a second direction. A flow resistance of the hydraulic fluid is larger when the ball is positioned in the third chamber than when the ball is moved towards the first or the second chambers.

Abstract: The present invention relates to a method of increasing the bioavailability and/or prolonging ophthalmic action of a drug, the method comprising instilling into the eye an aqueous suspension comprising reversible clusters of drug loaded nano-resin particles, said clusters having a D50 value of at least 2 micrometer and said drug loaded nano-resin particles have a particle size distribution characterized in that the D90 value is 70 nanometer to 900 nanometer. The present invention further relates to an aqueous suspension comprising reversible clusters of drug loaded nano-resin particles, said clusters have a D50 value of at least 2 micrometers and said drug loaded nano-resin particles have a particle size distribution characterized in that the D90 value is 70 nanometers to 900 nanometers.

Abstract: An electrode lead may comprise a flexible circuit that includes a planar dielectric substrate including an elongated lead substrate portion having opposing ends, an electrode carrying substrate portion disposed on one end of the lead substrate portion, and a connector substrate portion disposed on the other end of the lead substrate portion, wherein the lead substrate portion is pre-shaped into a three-dimensional structure. The flexible circuit may further include an electrically conductive trace extending from the connector substrate portion to the electrode carrying substrate portion, a first window formed in the connector substrate portion to expose the electrically conductive trace to form a connector pad, and a second window formed in the electrode carrying substrate portion to expose the electrically conductive trace to form an electrode pad. The electrode lead may further comprise a lead connector that incorporates the connector substrate portion.

Abstract: The present disclosure provides compositions that inhibit the SH2-containing inositol 5?phosphatase (SHIP) as well as methods using such composition for use in treating or ameliorating the effects of a medical condition in a subject. For examples, compositions including the general formula as disclosed herein are suitable for use herein.

Abstract: A live detection system, a thermal infrared (IR) imager and a method for power grid equipment are provided. The system includes an environmental parameter module for acquiring environmental temperature, humidity and wind speed data; a ranging module for measuring a linear distance to the power grid equipment; an equipment type recognition module for acquiring an image of the power grid equipment, and recognizing a type of the power grid equipment; an equipment material determination module for determining a material type of the power grid equipment; an emissivity setting module for setting an emissivity; an temperature measurement module for obtaining a temperature of the power grid equipment by focusing on positions of the power grid equipment which need temperature measurement; and a report generation module for selecting a corresponding diagnostic model, displaying a temperature measurement position and a temperature value, drawing a conclusion, and generating a report.

Abstract: The present invention is directed to a physiological recording device and, more particularly, to a physiological recording device that can be used without skin preparation or the use of electrolytic gels. The invention is further directed to an encouragement ring which stabilizes and helps situate the physiological recording device on a subject's skin to help provide a better electrical signal, increase surface area, and reduce and minimize noise and artifacts during the process of recording or monitoring a physiological signal. The invention is still further directed to surface features on a surface of the physiological recording device with a size and shape that will not substantially bend or break, which limits the depth of application of the recording device, and/or anchors the recording device during normal application. The invention is even further directed to a method for manufacturing a physiological recording device, and minimizing cost of manufacture.

Abstract: Provided is a method of compressing an occupancy map of a three-dimensional (3D) point cloud, and more specifically, a method of compressing an occupancy map of a point cloud in which an occupancy map image of a point cloud existing in a 3D space is compressed based on a compression quality or a patch-by-patch inspection method of the occupancy map image so that compression distortion is minimized when reconstructing the compressed occupancy map image so as to remarkably improve the quality of a reconstructed occupancy map image.

Abstract: A laser pulse energy amplification device and method, and a femtosecond laser are provided. The laser pulse energy amplification device includes a pulse amplifier and a pulse shaper that are connected in sequence. The pulse amplifier is connected to an output port of a seed laser source and is connected to the pulse shaper that outputs a femtosecond laser pulse. The seed laser source is configured to generate and input a seed laser pulse to the pulse amplifier. The pulse amplifier is configured to introduce a nonlinear phase shift into the seed laser pulse, perform energy amplification and spectral stretching, and output an energy-amplified laser pulse with a nonlinear phase to the pulse shaper. The pulse shaper is configured to measure a shape and/or the nonlinear phase of the energy-amplified laser pulse, and shape the energy-amplified laser pulse according to the shape and/or the nonlinear phase.

Abstract: A method for cleaning semiconductor wafer includes putting at least one wafer on a cassette bracket in a first cleaning tank filled with chemical solution; after said wafers have been processed in the first cleaning tank, transferring the wafers from the first cleaning tank to a second cleaning tank with the wafers immersing in the chemical solution; and after said wafers have been processed in the second cleaning tank, taking the wafers out of the second cleaning tank.

Abstract: Provided are methods and systems for remediating toxins present in feedstock that are used in processes to produce ethanol and other products.

Abstract: Covalent organic frameworks (COFs) usually crystallize as insoluble powders and their processing for suitable devices has been thought to be limited. Here, it is demonstrated that COFs can be mechanically pressed into shaped objects having anisotropic ordering with preferred orientation between the hk0 and 00l crystallographic planes. Pellets prepared from bulk COF powders impregnated with LiClO4 displayed room temperature conductivity up to 0.26 mS cm?1 and stability up to 10.0 V (vs. Li+/Li0). This outcome portends use of COFs as solid-state electrolytes in batteries.

Abstract: The present disclosure relates to a method for vascular imaging and determining dynamic vascular parameters of blood flow. According to an embodiment, the present disclosure relates to an apparatus and method of determining dynamic vascular parameters of blood flow, comprising acquiring two-dimensional projection images of a vascular region of interest at a predetermined frequency, the vascular region of interest being downstream of a site of vascular administration of a radio-opaque medium, identifying, within the acquired two-dimensional projection images, heterogeneities of the radio-opaque medium, and determining the dynamic vascular parameters of the blood flow based on spatial movements of the identified heterogeneities of the radio-opaque medium. In an embodiment, the predetermined frequency is greater than 100 Hz.

Abstract: An array imaging apparatus having discrete camera modules is disclosed. In one embodiment, the apparatus comprises a substrate; and heterogeneous camera modules attached to the substrate and in a geometric relationship with each other, the heterogeneous camera modules having a substantially similar photometric response.

Abstract: An example system includes: a landmark detection engine to detect landmark positions of landmarks in images based on facial detection; an optical flow landmark engine to determine the landmark positions in the images based on optical flow of the landmarks between the images; a landmark difference engine to determine, for a landmark in a given image: a distance between a detected landmark position and an optical flow landmark position of the landmark; and a weighted landmark determination engine to determine, for a first and second image, a position for the landmark in the second image based on: a respective detected landmark position and a respective optical flow position of the landmark in the second image; and respective distances, determined with the landmark difference engine, between a first detected landmark position of the landmark in the first image and respective optical flow landmark positions for the first and second images.

Abstract: Various embodiments of the present disclosure provide a scan-based architecture for register-transfer-level (RTL) or gate-level designs that improves the security of scan chain-based design-for-testability (DFT) structures. In various embodiments, the scan-based architecture includes invisible scan chains that are hidden in such a way that an attacker cannot easily identify or locate the invisible scan chains for exploitation and revealing internal secure information of the design. The invisible scan chains are dynamically configurable into a scan chain with select flip-flops, such that scan paths of the invisible scan chains may be different between different designs, chips, or testing operations. Various embodiments further employ key-based obfuscation by combining a scan control finite state machine with existing state machines within a design, which improves design security against unauthorized use and increases confidentiality.