Abstract: The present disclosure is concerned with 6-aza-nucleoside prodrugs that are capable of inhibiting a viral infection and methods of treating viral infections such as, for example, human immunodeficiency virus (HIV), human papillomavirus (HPV), chicken pox, infectious mononucleosis, mumps, measles, rubella, shingles, ebola, viral gastroenteritis, viral hepatitis, viral meningitis, human metapneumovirus, human parainfluenza virus type 1, parainfluenza virus type 2, parainfluenza virus type 3, respiratory syncytial virus, viral pneumonia, yellow fever virus, tick-borne encephalitis virus, Chikungunya virus (CHIKV), Venezuelan equine encephalitis (VEEV), Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), dengue (DENV), influenza, West Nile virus (WNV), zika (ZIKV), Middle East Respiratory Syndromes (MERS), Severe Acute Respiratory Syndrome (SARS), and coronavirus disease 2019 (COVID-19), using these compounds.

Abstract: A method of producing a syngas composition includes hydrolyzing a metal halide salt to form a hydrohalic acid and a hydroxide salt of the metal in the metal halide salt. The metal includes an alkaline earth metal or an alkali metal. The method includes reacting the hydrohalic acid with a metal carbonate salt, wherein the metal carbonate salt is a carbonate salt of the alkaline earth metal or alkali metal, to form CO2 and the metal halide salt. At least some of the metal halide salt formed from the reacting of the hydrohalic acid with the metal carbonate salt is recycled as at least some of the metal halide salt in the hydrolyzing of the metal halide salt to form the hydrohalic acid and the hydroxide salt. The method also includes electrolytically converting the CO2 and the water into the syngas composition including carbon monoxide and hydrogen.

Abstract: Methods and electroplating systems for controlling plating electrolyte concentration on an electrochemical plating apparatus for substrates are disclosed. A method involves: (a) providing an electroplating solution to an electroplating system; (b) electroplating the metal onto the substrate while the substrate is held in a cathode chamber of an electroplating cell of electroplating system; (c) supplying the make-up solution to the electroplating system via a make-up solution inlet; and (d) supplying the secondary electroplating solution to the electroplating system via a secondary electroplating solution inlet. The secondary electroplating solution includes some or all components of the electroplating solution. At least one component of the secondary electroplating solution has a concentration that significantly deviates from its target concentration.

Abstract: A collapsible sample collection device with a novel, collapsible 3D capture open affinity net dispersed throughout the volume of the container, said net with tethered affinity moieties, is designed to address the need for low-cost, simple harvesting and concentration of diagnostic analytes that generally does not require any ancillary equipment. The collection device generally permits analytes of interest to be efficiently harvested from body fluid samples, in one step, concentrated, collapsed into a flat mailing size, and protected from degradation without the need for traditional cold chain technologies. The concentration factor will increase sensitivity by several orders of magnitude when coupled with any type of downstream analyte measurement, including point of care testing. The collection device, in various embodiments, obviates the need for handling transport or storage of the fluid portion of the body fluid sample (e.g. blood, urine, saliva, etc.

Abstract: A method of and system for gate-level masking of secret data during a cryptographic process is described. A mask share is determined, wherein a first portion of the mask share includes a first number of zero-values and a second number of one-values, and a second portion of the mask share includes the first number of one-values and the second number of zero-values. Masked data values and the first portion of the mask share are input into a first portion of masked gate logic, and the masked data values and the second portion of the mask share are input into a second portion of the masked gate logic. A first output from the first portion of the masked gate logic and a second output from the second portion of the masked gate logic are identified, wherein either the first output or the second output is a zero-value.

Abstract: Disclosed are memory encryption systems and methods that rotate encryption keys for robust resistance against side-channel-analysis (SCA)-based attacks on communication paths between an encryption engine within a trust boundary and an external memory component. A key data structure has a plurality of keys that are used to encrypt a plurality of memory blocks in the external memory. The memory blocks encrypted with the oldest key of the key data structure are identified. Encrypted data is read from the identified memory blocks. The encrypted data is decrypted from the identified memory blocks. The data is then re-encrypted using the selected key that is newer than the oldest key, and re-written to the identified memory blocks.

Abstract: Disclosed are an intelligent bionic human body part model detection device and a method for manufacturing same. The device comprises: a bionic human body part model (1); and multiple optical fiber grating sensing units (5) which are integrated on an optical fibre and arranged at multiple pre-determined positions of the bionic human body part model (1). The device can improve the accuracy of the detection of pressure applied to the intelligent bionic human body part model.

Abstract: An active vortex generator adapts to a flow rate of fluid through and/or a heat flux applied through a heat exchanger channel to improve the heat transfer rate of the heat exchanger. In some implementations, the movement of the active vortex generator may be induced by the fluid flow through the heat exchanger channel. In some implementations, the movement of the active vortex generator may be induced through an externally applied force on the active vortex generator. An actuated active vortex generator is particularly suited to heat exchangers with high heat flux dissipation requirements. Locating an actuated active vortex generator proximate to such high heat flux dissipation locations provides for improved heat transfer that can be activated when needed, such as upon operation of a high heat flux component.

Abstract: A system and method for detection of x-rays is provided. An x-ray detector system may include an energy-integrating x-ray detector having an array of x-ray sensing elements that are configured to sense x-rays emitted from an x-ray source and generate energy-integrating x-ray data. The system may also include a photon-counting detector having another array of x-ray sensing elements configured to determine an interaction between individual x-ray photons with individual sensing elements of the another array of x-ray sensing elements to generate photon-counting x-ray data. The system may further include electronics configured to receive the energy-integrating x-ray data and the photon-counting x-ray data simultaneously.

Abstract: A full-body protection gear is disclosed. The protection gear includes a torso protector, an arm protector, and a lower body protector. The torso protector includes a protective vest defining a neck opening, a first arm opening, and a second arm opening. The torso protector includes a front shield, aback shield, a first pair of side shields, a second pair of side shields, a first shoulder shield and a second shoulder shield fixedly disposed on the protective vest. The arm protector includes a first part adapted to cover an upper arm region of a user extending from a shoulder to an elbow, and a second part adapted to be removably coupled with the first part and to cover a lower arm region of the user extending from the elbow to a palm. The lower body protector includes a first part adapted to cover pelvic region and an upper leg region of a user, and a second part removably coupled with the first part in a partial overlapping manner, and adapted to cover lower leg region of the user.

Abstract: Provided herein is a method and apparatus for venting of intravenous tubing to remove air bubbles, and more particularly, to a venting valve that allows air bubbles to escape along a venting path while not permitting fluid passage through the venting path. An example air extraction device may include: a chamber; a fluid inlet to convey fluid from intravenous tubing into the chamber; a fluid outlet to convey fluid from the chamber to intravenous tubing for supplying to a patient; a top portion of the chamber; a branch tube extending from the top portion of the chamber, where the branch tube receives air from the fluid in the chamber; and a ball received within the chamber, where the ball is configured to rise with an influx of fluid to the chamber from the fluid inlet and to seal off the branch tube from the chamber in response to the fluid level rising to the top portion of the chamber.

Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 150 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in rod photoreceptors of a gene when operatively linked to a nucleic acid sequence coding for said gene.

Abstract: Provided is a spiral coil and wireless power transmission and reception circuit including the spiral coil. The spiral coil includes a conducting wire forming one or more coil turns, and a height of one side of the conducting wire in a direction of a central portion of the spiral coil and a height of another side of the conducting wire in an opposite direction to the central portion of the spiral coil in each of the coil turns are different from each other and the conducting wire includes at least one slot formed by an empty space between the one side and the other side, and an upper surface positioned above the one side and the other side and connecting the one side and the other side.

Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.

Abstract: Systems and methods herein provide for Multi-Input/Multi-Output (MIMO) processing. In one embodiment, a MIMO system comprises a receiver operable to receive a plurality of spatially multiplexed data streams. The system also comprises a processor operable to embed a maximum likelihood (ML) detection algorithm onto a quantum annealer, and to decode the spatially multiplexed data streams via the embedded ML to detect data bits of a plurality of users.

Abstract: A digital certificate processing method includes: receiving a distribution request for a digital certificate, wherein the digital certificate does not contain validity period information; acquiring a verification result for the digital certificate; and according to the verification result, recording the digital certificate which has passed verification to a blockchain.

Abstract: The present application relates to a composite binding agent grinding wheel, wherein a weight percentage of each raw material of the grinding wheel is: 45-65% of pretreatment abrasive, 8-20% of resin bonding agent, 5-12% of hexagonal boron nitride, 5-10% of silicon dioxide, 5-15% of ceramic powder, 6-12% of prealloy powder bonding agent, and 1-3% of boron powder. The composite binding agent super-hard grinding wheel prepared by the present application can achieve nano-level grinding surface quality when grinding epitaxial wafers, and the grinding wheel has strong self-sharpening and high sharpness. It has obvious advantages in the finishing of silicon carbide crystal epitaxial wafers, which can solve the current limitations of back thinning processing of silicon carbide crystal epitaxial wafers.

Abstract: Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed.

Abstract: A three-dimensional (3D) video reconstruction method, an encoder and a decoder are provided, comprising obtaining a list of video content screens or video content frames of an object from the 3D video; obtaining a list of depth screens of the 3D video; adding a shape screen to each video frame of the 3D video; superimposing each of the video content screens or video content frames with the depth screen and the shape screen to form a shape identification library; and storing the shape identification library at a header of a compressed file for unmasking of the object. The shape recognition list format may significantly reduce the storage size and increase the compression ratio by replacing the original shape with the identifications, and help improve the rendering quality.

Abstract: A computing system includes a host device and a root of trust (RoT) device for performing batch encryption and decryption operations facilitated by a direct memory access (DMA) engine. The host device generates a command table for batch processing of a set of address tables that each describe a set of data blocks of a file to be encrypted or decrypted. The DMA engine facilitates a DMA transfer of the command table from the host memory to an RoT memory of the RoT device. The RoT device then performs batch processing of the address tables referenced in the command table. For each address table, the DMA engine copies a set of data blocks from the host memory to the RoT memory, a cryptographic engine encrypts or decrypts the data blocks, and the DMA engine copies the transformed data blocks back to the host memory.