Patents Assigned to Research
  • Publication number: 20230399387
    Abstract: The present disclosure is directed to method of diagnosing and treating heart disease using antibodies that bind to Cofilin, A? and/or Tau.
    Type: Application
    Filed: November 5, 2021
    Publication date: December 14, 2023
    Applicants: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Federica DEL MONTE, Rakez KAYED
  • Publication number: 20230398284
    Abstract: A flexible elongate member with the ability to deliver a material through a medium-delivery channel defined within a wall thereof. The flexible elongate member may have a tubular wall defining a lumen therethrough, the medium-delivery channel being formed within the tubular wall. The flexible elongate member may be a reinforced flexible tubular elongate member with a reinforcing layer within the tubular wall thereof. One or more filaments forming the reinforcing layer may be hollow to define the medium-delivery channel extending through the reinforced flexible tubular elongate member.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 14, 2023
    Applicants: BOSTON SCIENTIFIC SCIMED, INC., MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Jason John Matteson, JR., Matthew Maciej, Mitchell Nelson, Paul A. Friedman
  • Publication number: 20230398559
    Abstract: A parallelized droplet generating apparatus may include: a first inlet configured to introduce a continuous-phase fluid; a second inlet configured to introduce a dispersed-phase fluid; a first splitter configured to split the continuous-phase fluid introduced through the first inlet; a second splitter configured to split the dispersed-phase fluid introduced through the second inlet; and a droplet generator configured to combine the continuous-phase fluid split by the first splitter and the dispersed-phase fluid split by the second splitter to generate droplets.
    Type: Application
    Filed: June 8, 2023
    Publication date: December 14, 2023
    Applicant: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
    Inventors: Jinkee LEE, Seonghun SHIN, Seongsu CHO
  • Publication number: 20230398136
    Abstract: A composition for the treatment of diarrheal and other diseases, comprising a reaction product of one or more polyphenol compound; sucralfate; and at least one acid.
    Type: Application
    Filed: August 20, 2023
    Publication date: December 14, 2023
    Applicant: VANESSA RESEARCH, INC.
    Inventors: Dmitry KRAVTSOV, Norman GRAY
  • Publication number: 20230401448
    Abstract: A method of training a neural network may be provided. The method may include receiving a raw data set and normalizing the raw data set using a group normalization layer to generate a training data set for training a neural network, wherein the group normalization layer segments the raw data set into a plurality of groups of a predetermined size. The method may also include randomly initializing the neural network by randomly assigning values to a plurality of weights corresponding to a plurality of layers of the neural network. The method may further include training the neural network using the training data set.
    Type: Application
    Filed: June 9, 2023
    Publication date: December 14, 2023
    Applicant: NTT RESEARCH, INC.
    Inventors: Hidenori TANAKA, Ekdeep Singh Lubana
  • Publication number: 20230400406
    Abstract: Disclosed are a material classification apparatus and method based on a multi-spectral NIR band. A material classification apparatus based on a multi-spectral NIR band includes: an input unit configured to acquire a multi-band NIR image of a target; an attention module configured to generate a spatio-spectral correlation map considering spatial information on the multi-band NIR image and a correlation between each band; and a classification model unit configured to analyze the spatio-spectral correlation map and output a material classification label for the target.
    Type: Application
    Filed: June 9, 2023
    Publication date: December 14, 2023
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Jong Ok KIM, Dong Keun HAN
  • Publication number: 20230401721
    Abstract: A method for 3D object perception is described. The method includes extracting features from each image of a synthetic stereo pair of images. The method also includes generating a low-resolution disparity image based on the features extracted from each image of the synthetic stereo pair images. The method further includes predicting, by a trained neural network, a feature map based on the low-resolution disparity image and one of the synthetic stereo pair of images. The method also includes generating, by a perception prediction head, a perception prediction of a detected 3D object based on the feature map predicted by the trained neural network.
    Type: Application
    Filed: June 13, 2022
    Publication date: December 14, 2023
    Applicants: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Thomas KOLLAR, Kevin STONE, Michael LASKEY, Mark Edward TJERSLAND
  • Publication number: 20230399314
    Abstract: The present disclosure provides a novel compound for effectively inhibiting the activity of CD73, a preparation method thereof, and use thereof in the preparation of drugs, and the novel compound is a compound represented by formula I, or a tautomer, stereoisomer, hydrate, solvate, pharmaceutically acceptable salt, or prodrug thereof.
    Type: Application
    Filed: November 5, 2021
    Publication date: December 14, 2023
    Applicant: WUHAN HUMANWELL INNOVATIVE DRUG RESEARCH AND DEVELOPMENT CENTER LIMITED COMPANY
    Inventors: Xuejun ZHANG, Shaohua CHANG, Dabing YE, Sijun LEI, Yonggang WANG, Yong LIU, Hongna SUN, Jun YANG, Lie LI
  • Publication number: 20230399658
    Abstract: Provided herein are compositions and methods for packaging a recombinant adeno-associated virus (rAAV) particle comprising using inverted terminal repeats (ITRs) and rep genes of different serotypes and/or using chimeric rep genes.
    Type: Application
    Filed: January 5, 2023
    Publication date: December 14, 2023
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Mavis Agbandje-McKenna, Mario Mietzsch, Robert McKenna
  • Publication number: 20230399653
    Abstract: The present invention relates to processes for extracting lipid from vegetative plant parts such as leaves, stems, roots and tubers, and for producing industrial products such as hydrocarbon products from the lipids. Preferred industrial products include alkyl esters which may be blended with petroleum based fuels.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 14, 2023
    Applicant: Commonwealth Scientific and Industrial Research Organisation
    Inventors: Thomas Vanhercke, James Robertson Petrie, Ana El Tahchy, Surinder Pal Singh, Qing Liu
  • Publication number: 20230400450
    Abstract: A biological sensing system, comprising a microelectrode array having a plurality of islands that are thermally isolated from each other and are interconnected by flexible nano-scale wires. An embedded complementary metal oxide semiconductor (CMOS) instrumentation amplifier and wireless communication circuitry may be operatively connected to the microelectrode array and embedded within input/output pads connected to the wires at the periphery of the array.
    Type: Application
    Filed: April 14, 2023
    Publication date: December 14, 2023
    Applicant: Purdue Research Foundation
    Inventors: Hossein Pajouhi, Saeed Mohammadi, Mojgan Sarmadi
  • Publication number: 20230403555
    Abstract: System and methods for authenticating a UE, using one of two novel immutable factors, for granting access to premium resources. One immutable factor includes a public ID of the UE and its true geolocation, while the other consists of the SDID of UE and its true geolocation. For the public ID based system, a non-terrestrial communication network verifies geolocation of an LBS provider by comparing geolocation with the publicly known geolocation of the LBS provider After receiving true geolocation coordinates, LBS provider grants or denies UE's resource access request by comparing geolocation of UE with the geolocation(s) retrieved from the credential database which contains a list of preauthorized geolocation(s) for the legitimate users of a UE. For the SDID based system, an authentication system verifies SDID of both the requesting UE and LBS provider by comparing transmitted SDID with the SDID retrieved from an SDID database.
    Type: Application
    Filed: May 24, 2023
    Publication date: December 14, 2023
    Applicant: Wi-LAN Research Inc.
    Inventors: Muddassar Farooq, Taimur Hayat Khan, Arslan Mumtaz, Zain Noman, Kenneth Stanwood, Rashad Ramzan
  • Publication number: 20230398142
    Abstract: Provided is a method for preventing or treating urological chronic pelvic pain syndrome (UCPPS) in a subject that includes administering an effective amount of cerium oxide nanoparticles (CeNPs) to the subject. Also provided is a method for preventing or treating an UCPPS in a subject that includes administering to the subject a pharmaceutical composition comprising an effective amount of the CeNPs and a pharmaceutically acceptable carrier thereof.
    Type: Application
    Filed: June 8, 2022
    Publication date: December 14, 2023
    Applicants: National Health Research Institutes, National Taiwan University, National Chung Hsing University, National Cheng Kung University
    Inventors: Wei-Chih LIEN, Feng-Huei Lin, Hui-Min Wang, Tak Shing Ching, Xin-Ran Zhou, Ya-Jyun Liang, Chia-Yih Wang, Fu-I Lu, Huei-Cih Chang
  • Publication number: 20230401119
    Abstract: A two-sided time-sharing driving and acquisition system based on dry contacts comprises k dry contacts, a processor, p acquisition circuits, and m driving circuits. The p acquisition circuits are evenly divided into two groups which are separately disposed at two sides of the k dry contacts. The m driving circuits are separately disposed at the two sides of the k dry contacts. A system fault detection method and the two-sided time-sharing driving and acquisition system have the following advantages: the state of input acquisition circuits and cables monitored in real time during system debugging or running, and faults caused by exceptions of the acquisition circuits and the cables can be reported in time.
    Type: Application
    Filed: March 2, 2023
    Publication date: December 14, 2023
    Applicants: Jiangsu Huachuang Microsystem Company Limited, Nanjing Research Institute of Electronics Technology
    Inventors: Yue WANG, Yu ZHENG, Kun QI, Dingliang XU, Yong QI, Guoqiang HE
  • Publication number: 20230398257
    Abstract: An object of the present invention is to provide a bioabsorbable and stretchable fibrous medical material that enables formation of ligation which provides a small and hard-to-unravel knot even with a weak force. The present invention provides a fibrous medical material which is a fibrous material composed of a molded article provided by spinning and drawing a bioabsorbable aliphatic polymer, wherein an elongation at break is 75% or greater, an intermediate elastic modulus in tension at a strain ranging from 0.25% and 10% is lower than an initial elastic modulus in tension at a strain ranging from 0.05% to 0.25%, the intermediate elastic modulus in tension is 400 MPa or less, and a residual strain rate after 100% deformation is 70% or less.
    Type: Application
    Filed: October 25, 2021
    Publication date: December 14, 2023
    Applicants: MITSUBISHI GAS CHEMICAL COMPANY, INC., National University Corporation Tokai National Higher Education and Research System
    Inventors: Akira MAEHARA, Hitoshi HIRATA, Atsuhiko MURAYAMA, Yasunobu NAKAGAWA
  • Publication number: 20230397605
    Abstract: The invention provides a method for increasing the growth of a plant or the harvest yield of a plant comprising, contacting the plant with a trisulfide or a tetrasulfide. The methods of the invention may conveniently be employed in indoor growth facilities or in conjunction with a hydroponic growth system.
    Type: Application
    Filed: October 19, 2021
    Publication date: December 14, 2023
    Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Ned B. BOWDEN, Erin E. IRISH, Aliasgar SALEM, Justin M. CARTER, Eric M. BROWN
  • Publication number: 20230399407
    Abstract: The present invention relates to an antibody having enhanced binding affinity for human Fc alpha receptor and a technique for maximizing a mechanism of antibody action by using same. Antibodies specific for Fc alpha receptors or immunologically active fragments thereof according to the present invention are in the form of IgG and bind to Fc alpha receptors of effector cells, especially, neutrophils, which are most abundant in mammals, thereby overcoming the disadvantages of conventional IgA antibodies and maximizing an effector function in various antibody therapeutic agents, which leads to maximizing the mechanism of antibody action (ADCC and ADCP). Thus, various Fc-fused protein therapeutic agents using same can be advantageously utilized as antibody drugs with enhanced effector functions.
    Type: Application
    Filed: November 3, 2021
    Publication date: December 14, 2023
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Sang Taek JUNG, Ji Sun LEE, Bo Mi KIM
  • Publication number: 20230398091
    Abstract: Self-assembling compounds for the formation of ion channels in biological membranes include monoacylated benzo(crown-ether) (MAcBCE) compounds and monoalkylated benzo(crown-ether) (MAkBCE) compounds. Methods of preparing the MAcBCE and MAkBCE compounds and methods of forming an ion channel in a biological membrane are also disclosed.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 14, 2023
    Applicants: Washington University, Wisconsin Alumni Research Foundation
    Inventors: Baron Chanda, Willy Carrasquel Ursulaez, Jennifer Schomaker, Corey Jones, Mahzad Dehghany
  • Publication number: 20230400302
    Abstract: The present disclosure provides a system and a method for measuring water capacity of polar lakes, and relates to the technical field of lake water capacity measurement. The method comprises the steps: controlling an unmanned aerial vehicle to move along with an unmanned underwater vehicle at a preset height right above the unmanned underwater vehicle by utilizing an ADRC algorithm; obtaining lake surface point cloud data, under-lake point cloud data and under-lake single-beam ranging data so as to construct a water three-dimensional topographic map, a lake coastal three-dimensional topographic map and a lake bottom three-dimensional topographic map under the same coordinate system, and then determining the lake water capacity.
    Type: Application
    Filed: August 19, 2022
    Publication date: December 14, 2023
    Applicant: Polar Research Institute of China
    Inventors: JINGXUE GUO, YUCHEN WANG, YANG SUN
  • Publication number: 20230401068
    Abstract: A method for improving an accuracy of a loop branch prediction algorithm by a bypass circuit, comprising: adding a bypass circuit to a loop branch prediction algorithm; and for three pcs entering a pipeline, enabling pc1 fetched in an if0 stage to enter a hybrid branch predictor, and registering pc1; obtaining branch prediction information in an if1 stage, and making a comparison in an if2 stage to obtain a prediction result, registering the prediction result obtained in the if2 stage, and processing pc2 and pc3 in a same way.
    Type: Application
    Filed: February 28, 2023
    Publication date: December 14, 2023
    Applicants: Jiangsu Huachuang Microsystem Company Limited, Nanjing Research Institute of Electronics Technology
    Inventors: Jiong LOU, Shiping LI, Sibo YANG, Ming LI, Wenjun HAN, Zhiyong LEI