Abstract: A dual autoencoder includes a first domain encoder for mapping a first domain image into a first latent space, a first domain decoder for reconstructing the first domain image, a second domain encoder for mapping a second domain image into a second latent space, a second domain decoder for reconstructing the second domain image; and a latent space association network for defining a cross-domain relationship between the first domain and the second domain. An image translation method using a dual encoder, may include: taking a first domain image as an input; determining an output condition; if the output condition is the same domain, reconstructing the first domain image by a first domain encoder and a first domain decoder; and if the output condition is the cross domain, reconstructing a second domain image by the first domain encoder, a latent space association network, and a second domain decoder.
Type:
Grant
Filed:
February 26, 2021
Date of Patent:
December 19, 2023
Assignee:
Research & Business Foundation Sungkyunkwan University
Abstract: A method for adjusting sleep time based on sensing data and an electronic device are provided. In the method, a sensor is disabled in a sleep duration of the ith operation cycle, and the sensor is enabled in a detection duration of the ith operation cycle. Multiple sensing data corresponding to the ith operation cycle are obtained from the sensor. A detection duration and a sleep duration of the i+1th operation cycle are determined based on the sensing data obtained in the detection duration of the ith operation cycle.
Type:
Grant
Filed:
March 28, 2022
Date of Patent:
December 19, 2023
Assignee:
Industrial Technology Research Institute
Inventors:
Chang-Hsien Chen, Yi-Cheng Chung, Bo-Yi Ye
Abstract: A system for indexing, updating, and search haplotypes for genetic genealogical discovery in genotype databases. The system includes a pool of genetic indexes, a haplotype ingestion engine, and a haplotype query engine. The haplotypes of a number of individuals in a genotype database are indexed by a pool of multiple panels, and each panel pool can be dynamically updated by the insertion or deletion of individual haplotypes. A genetic genealogical search of a query haplotype against the database is achieved by first projecting the query onto a subset of panels in the pool, then conducting long match queries over each panel, and finally aggregating the identified long matches into Identical-by-Descent segments, i.e., DNA matches, between the query and the haplotypes in the database.
Type:
Grant
Filed:
April 3, 2020
Date of Patent:
December 19, 2023
Assignees:
University of Central Florida Research Foundation, Inc., The Board of Regents of the University of Texas System
Abstract: The respiratory microbiomes of neonates and those with bronchopulmonary disease have been characterized. Provided are probiotic compositions, which can include at least one living bacterial strain and at least one killed bacterial strain, that can comprise a combination of Lactobacilli species, 5 that when delivered to the bronchi or lungs of a patient can provide a reduction in the symptoms of a bronchopulmonary disease.
Type:
Grant
Filed:
July 23, 2021
Date of Patent:
December 19, 2023
Assignee:
The UAB Research Foundation
Inventors:
Charitharth Vivek Lal, Namasivayam Ambalavanan, Amit Gaggar, Casey Morrow
Abstract: An isolated cell having a central memory T-lymphocyte (Tcm) phenotype, the cell being tolerance-inducing cell and capable of homing to the lymph nodes following transplantation, the cell being transduced to express a cell surface receptor comprising a T cell receptor signaling module is disclosed. Methods of generating same and using same are also disclosed.
Abstract: A system including an optical system having at least one refractive or reflective element, the optical system configured to substantially receive electromagnetic radiation emanating from a source, the optical system being located within a Dewar, a support structure, support structure being mechanically disposed between the optical system and a surface of the Dewar, the support structure having substantially low thermal conductance, a cold source; the cold source being located within the Dewar, a thermal link, the thermal link being mechanically disposed between the optical system and the cold source, the thermal link being substantially flexible and having substantially high thermal conductance.
Abstract: Embodiments of the invention provide a method of reducing colonization of a subject's anterior nares and/or nasal cavity by a microorganism (e.g., Staphylococcus aureus). In some aspects, the method may include administering a pharmaceutical composition to the subject, wherein the pharmaceutical composition comprises a therapeutically effective amount of at least one probiotic.
Type:
Grant
Filed:
July 20, 2022
Date of Patent:
December 19, 2023
Assignees:
The Translational Genomics Research Institute, Arizona Board of Regents on behalf of Northern Arizona University
Abstract: As described herein, a hybrid voltage sensor genetically-encoded voltage indicator (GEVI) for mitochondria or endoplasmic reticulum includes a transmembrane domain, and a fluorescent protein, wherein a terminus of the transmembrane domain and a terminus of the fluorescent protein are covalently linked directly or by a linker comprising 1 to 20 amino acids, and wherein the transmembrane domain comprises SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4 or a peptide with greater than 85%, 90%, 95% or 98% identity to SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4. Also described are expression vectors, expression cassettes, and organelle membranes, as well as methods of determining the voltage across an organelle using the GEVIs.
Abstract: Complex compounds of transition metals according to formula (1) wherein the M(CO)3+ tricarbonyl-metal core forms a complex with the cyclopentadienyl anion linked to heterocyclic moieties of the benzothiazole, benzimidazole and benzoxazole families. The compounds exhibit high blood-brain barrier permeability and can be used in the diagnosis and/or treatment of diseases of the Central Nervous System.
Type:
Grant
Filed:
March 22, 2019
Date of Patent:
December 19, 2023
Assignee:
NATIONAL CENTRE FOR SCIENTIFIC RESEARCH “DEMOKRITOS”
Inventors:
Maria Pelecanou Zampara, Marina Sagnou, Minas Papadopoulos, Ioannis Pirmettis, Barbara Mavroidi, Antonio Shegani
Abstract: An electrostatic chuck for a substrate processing system is provided. The electrostatic chuck includes: a top plate configured to electrostatically clamp to a substrate and formed of ceramic; an intermediate layer disposed below the top plate; and a baseplate disposed below the intermediate layer and formed of ceramic. The intermediate layer bonds the top plate to the baseplate.
Type:
Grant
Filed:
February 23, 2018
Date of Patent:
December 19, 2023
Assignee:
Lam Research Corporation
Inventors:
Feng Wang, Keith Gaff, Christopher Kimball
Abstract: The present invention provides redesigned soluble coronavirus S protein derived immunogens that are stabilized via specific modifications in the wildtype soluble S sequences. Also provided in the invention are nanoparticle vaccines that contain the redesigned soluble S immunogens displayed on self-assembling nanoparticles. Polynucleotide sequences encoding the redesigned immunogens and the nanoparticle vaccines are also provided in the invention. The invention further provides methods of using the vaccine compositions in various therapeutic applications, e.g., for preventing or treating coronaviral infections.
Abstract: Disclosed is a best view spot generating server which includes a virtual tour providing server that communicates with a user terminal over a network and generates a best view spot associated with a three-dimensional object included in a virtual space, and a database that operates in conjunction with the virtual tour providing server and stores data associated with the virtual space, data associated with the three-dimensional object, and data associated with the best view spot.
Type:
Grant
Filed:
December 2, 2021
Date of Patent:
December 19, 2023
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: A piezoelectric artificial artery can be 3D printed to provide the real-time precise sensing of blood pressure and vessel motion patterns enabling early detection of partial occlusions. An electric-field assisted 3D printing method allows for rapid printing and simultaneously poled complex ferroelectric structures with high fidelity and good piezoelectric performance. The print material consists of ferroelectric potassium sodium niobate (KNN) particles embedded within a ferroelectric polyvinylidene fluoride (PVDF) polymer matrix.
Abstract: A brazing wire includes a brazing tube having an inner cavity and a flux filled in the inner cavity. A trench is provided on an outer peripheral surface of the brazing tube, and the trench extends along an axis of the brazing tube or spirally extends around the axis. A forming mold of the brazing wire includes a mold body having a molding cavity therein. An inner wall of the molding cavity is provided with a protrusion. When the brazing wire passes through the forming mold, the protrusion is used to form the trench. The forming method of the brazing wire includes the following steps. The brazing tube passes through the forming mold, and the trench is formed on the outer peripheral surface of the brazing tube by the protrusion. The trench extends along the axis of the brazing tube or spirally extends around the axis.
Type:
Grant
Filed:
August 26, 2021
Date of Patent:
December 19, 2023
Assignee:
ZHENGZHOU RESEARCH INSTITUTE OF MECHANICAL ENGINEERING CO., LTD.
Inventors:
Sujuan Zhong, Weimin Long, Yinyin Pei, Lei Zhang, Xiupeng Li, Yuanxun Shen, Yunyue Li, Luyi Wang
Abstract: A method of identifying causal relationships includes receiving data comprising a set of values corresponding to one or more variables, and generating a list of candidate causal models of relationships between or within the variables. The list is ranked based on a likelihood of each candidate causal model, wherein the likelihood includes at least a correlation value. The method further includes receiving feedback identifying a candidate causal model and a change in rank of the candidate causal model, re-ranking the list based on the feedback, and displaying the re-ranked list. The method generates an intervention comprising a suggested modification corresponding to a variable of a selected causal model among the candidate causal models in the re-ranked list, receives additional data corresponding to the variable of the suggested modification and evaluates the additional data to determine whether the likelihood of the selected causal model has changed.
Abstract: Embodiments of a recombinant human Parainfluenza Virus (hPIV) F ectodomain trimer stabilized in a prefusion conformation are provided. Also disclosed are nucleic acids encoding the hPIV F ectodomain trimer and methods of producing the hPIV F ectodomain trimer. Methods for inducing an immune response in a subject are also disclosed. In some embodiments, the method can be a method for treating or inhibiting a hPIV infection in a subject by administering a effective amount of the recombinant hPIV F ectodomain trimer to the subject.
Type:
Grant
Filed:
July 16, 2021
Date of Patent:
December 19, 2023
Assignees:
The United States of America, as represented by the Secretary, Department of Health and Human Services, Institute for Research in Biomedicine
Inventors:
Baoshan Zhang, Guillaume Stewart-Jones, John Mascola, Kai Xu, Gwo-Yu Chuang, Li Ou, Peter Kwong, Yaroslav Tsybovsky, Wing-Pui Kong, Aliaksandr Druz, Davide Corti, Antonio Lanzavecchia
Abstract: A double-sided optically clear adhesive is provided. The double-sided optically clear adhesive includes a first adhesive layer and a second adhesive layer. The first adhesive layer includes a first resin and a first thermal-crosslinking agent. The first resin includes a hydroxyl group. The first thermal-crosslinking agent includes a first group. The second adhesive layer includes a second resin and a second thermal-crosslinking agent. The second resin includes a hydroxyl group. The second thermal-crosslinking agent includes a second group. The ratio of the equivalent number of the first group of the first thermal-crosslinking agent to the equivalent number of the hydroxyl group of the first resin is represented by r1. The ratio of the equivalent number of the second group of the second thermal-crosslinking agent to the equivalent number of the hydroxyl group of the second resin is represented by r2, wherein r1<r2?0.8 and r2?r1?0.025.
Type:
Grant
Filed:
June 2, 2022
Date of Patent:
December 19, 2023
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: A device and method for printing 3D articles including electronic and functional elements including 3D printer and a plasma jet printer based on a dielectric barrier atmospheric pressure plasma jet system in which both printing and in-situ treatment and post-deposition treatment can be carried out to tailor the materials characteristics. Plasma jet printer comprising of electrodes in the nozzle/print head for applying electric field and generating atmospheric plasma that could be used for non-gravity based highly directional printing in any direction. Integration of dielectric barrier plasma printer and plasma treatment jets with the 3D printer increases the capability of embedding high performance electronics in a 3D printed structure aiding in additive manufacturing of functional devices. Ability to use a range of materials for print head assembly including micro machined silicon increases the resolution of the plasma jet printer to sub-micron level.
Type:
Grant
Filed:
February 8, 2022
Date of Patent:
December 19, 2023
Assignee:
UNIVERSITIES SPACE RESEARCH ASSOCIATION
Inventors:
Ramprasad Gandhiraman, Meyya Meyyappan, Jessica E. Koehne
Abstract: A process for producing para-xylene and ethylbenzene from C8 aromatics containing ethylbenzene includes the steps of sending C8 aromatics containing ethylbenzene to an ethylbenzene liquid-phase adsorption separation device, wherein a suction liquid containing ethylbenzene and a suction residual liquid are obtained after the adsorption separation, and the desorbents in the suction liquid and the suction residual liquid are removed to obtain ethylbenzene and a suction residual oil; sending the suction residual oil to a para-xylene adsorption separation device, and unadsorbed components are discharged as a raffinate from the adsorbent bed; the adsorbent bed is rinsed with a desorbent to desorb the para-xylene therein and obtain an extract; the desorbents in the extract and the raffinate are respectively removed to obtain para-xylene and a raffinate oil; sending the raffinate oil to a xylene isomerization device to carry out xylene isomerization, and the isomerization product is fractionated.
Type:
Grant
Filed:
September 28, 2020
Date of Patent:
December 19, 2023
Assignees:
CHINA PETROLEUM & CHEMICAL CORPORATION, RESEARCH INSTITUTE OF PETROLEUM PROCESSING, SINOPEC