Abstract: Provided are a recombinant microorganism, a composition comprising the same, and a method of producing a target product by using the same, the recombinant microorganism comprising a polynucleotide encoding a target product-binding protein fused to a secretion signal sequence.

Abstract: System, methods, and other embodiments described herein relate to an improved approach to training a depth model to derive depth estimates from monocular images using cost volumes. In one embodiment, a method includes predicting, using a depth model, depth values from at least one input image that is a monocular image. The method includes generating a cost volume by sampling the depth values corresponding to bins of the cost volume. The method includes determining loss values for the bins of the cost volume. The method includes training the depth model according to the loss values of the cost volume.

Abstract: The instant invention describes macrocyclic compounds having antiproliferation activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders.

Abstract: Antibodies and antigen-binding fragments thereof that bind the human voltage-gated sodium channel Nav1.7? protein subunit (Nav1.7 binders) are described. In particular embodiments, the Nav1.7 binders comprise a heavy-chain immunoglobulin single variable domain (ISVD or VHH).

Abstract: A method for performing a nonlinear optical operation includes pumping a laser with an optical signal at a pump wavelength and pumping the laser with an electronic or optical bias that acts as a hyperparameter, filtering out optical output at the pump wavelength so that only light at a lasing wavelength exits the laser, and collecting light exiting the laser for further optical processing or detection.

Abstract: A method of manufacturing a semiconductor device includes forming a channel layer on a substrate, forming a mask on the channel layer, surface-treating an exposed surface of the channel layer exposed from the mask, forming an electrode on the exposed surface of the channel layer, and removing the mask. The channel layer includes a two-dimensional material, and the surface-treating of the exposed surface of the channel layer includes surface-treating the exposed surface of the channel layer with HCl.

Abstract: The present invention relates to an adenine base editor from which cytosine editing activity is removed, a method of editing an adenine base, and method of editing an adenine base. In the present invention, it was confirmed that four mutations (V106W, D108Q, F148A and F149A) in adenosine deaminase increase the specificity for adenine editing by reducing cytosine base editing efficiency, and ABE variants were manufactured by introducing respective mutations into a variety of more improved adenine base editors than ABEmax, and tested, confirming that the mutations significantly decrease a cytosine editing effect. Therefore, the adenine base editor according to the present invention is able to more accurately edit adenine, and the method of editing an adenine base can be effectively used in the field of gene therapy that has to accurately edit only adenine in all living organisms including humans, plants and bacteria or novel crop development.

Abstract: A robotic arm includes a suction tool including a suction mechanism, a first pump, and a second pump. The first pump is operable to provide a first suction force and a first flow rate to the suction mechanism, and the second pump is operable to provide a second suction force and a second flow rate to the suction mechanism. A connection member places the first pump and the second pump in fluid communication with the suction mechanism.

Abstract: A method and an apparatus for video coding using a video-characteristic-based context model are disclosed. The video coding method and the video coding apparatus determine a context model optimized for an individual video on the basis of information in which various characteristics of the individual video are reflected in entropy encoding and decoding using context adaptive binary arithmetic coding (CABAC).

Abstract: A long-distance high-voltage cable fault degree detection method. A cable fault positioning curve is obtained by using a frequency-domain reflection method, and a cable fault positioning compensation curve is determined by means of theoretical calculation in combination with the parameters of a frequency-domain incident signal, cable structure parameters, and characteristic parameters of each layer of materials of the field test; furthermore, a cable fault diagnosis curve is determined on the basis of the cable fault positioning curve and the cable fault positioning compensation curve, the severity of the fault is determined by means of the amplitude of a peak point of the cable fault diagnosis curve, and the accuracy of long-distance high-voltage cable fault degree diagnosis is effectively improved.

Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.

Abstract: Provided is an electromagnetic radiation method and an apparatus for performing the same. The electromagnetic radiation apparatus includes a signal generator configured to generate a first electromagnetic signal configured with an uplink and a downlink and scale and radiate power of the first electromagnetic signal in order to evaluate the first electromagnetic signal as a second electromagnetic signal configured only with a downlink, and a radiation chamber in which cell containers configured with cells are arranged in a circle in order to evenly irradiate a scaled first electromagnetic signal to the cells.

Abstract: A method of conditional neural ground planes for static-dynamic disentanglement is described. The method includes extracting, using a convolutional neural network (CNN), CNN image features from an image to form a feature tensor. The method also includes resampling unprojected 2D features of the feature tensor to form feature pillars. The method further includes aggregating the feature pillars to form an entangled neural ground plane. The method also includes decomposing the entangled neural ground plane into a static neural ground plane and a dynamic neural ground plane.

Abstract: A method and an apparatus for video coding using intra sub-block prediction of a chroma block are disclosed. The video coding method and the apparatus adaptively apply a sub-block split method, transmission information, and a transform method in performing intra prediction on chroma signals of a current block using an intra sub-partitions (ISP) mode.

Abstract: The use of an unctuous sealing material (high viscosity liquid bordering on, or having, solid behavior at low shear forces) for sealing open pore, highly crushable suction cups allows for increased surface conformation for fast secure vacuum gripping, and maintenance of the pressure differential with lower energy in view of the seal. Furthermore, fast grasping is demonstrated if the unctuous sealing material protrudes from the lip.

Abstract: An embodiment of the inventive concept provides a thin film transistor and a manufacturing method of the same. The manufacturing method includes forming a data electrode on one side of a substrate, forming a spacer layer on a portion of the data electrode and the other side of the substrate, forming a drain electrode on a top surface of the spacer layer, forming an active layer on a sidewall of the spacer layer, the drain electrode, and the data electrode, forming a gate insulation film that covers the active layer on the sidewall of the spacer layer, and forming a doped layer on the gate insulation film and the active layer outside the gate insulation film to form impurity regions at both sides, respectively, of the active layer.

Abstract: Compositions and methods for supporting health, especially renal health, comprising ketonic agents that recapitulate beneficial effects of ketosis by exogenously administered agents. The agents include beta-hydroxybutyrate (BHB), analogs thereof, and GPR109A agonists. The agents may further include crystal precipitation inhibitors which synergistically improve treatment of certain renal conditions, such as citrate. The agents may be used in dietary supplements and therapeutic compositions for the treatment of cystic kidney diseases such as polycystic kidney disease, ciliopathies, and other conditions. Certain formulations enable convenient administration of the beneficial combination product in powdered form for mixing with liquid. Such formulations can be salt-balanced, and may be free of sodium and/or silicates, and are well tolerated. The formulations may be provided in a container and measuring implement to enable convenient measurement of dosages.

Abstract: A video coding method and an apparatus using an adaptive order of intra sub-partitions are provided. The video coding method and apparatus adaptively determine an encoding/decoding order of subblocks based on at least one of a shape of the subblock, a size of the subblock, a sub-splitting direction, and a prediction mode in performing intra prediction of the subblocks split from a current block using an ISP mode.

Abstract: One embodiment provides a method and a system for computing diagnoses for a physical system. During operation, the system can obtain a design of the physical system, generate a design of a diagnostic system by augmenting the design of the physical system based on a number of fault-emulating subsystems, and convert the design of the diagnostic system into a polynomial formula comprising a plurality of variables. The plurality of variables can include inputs and outputs of the original physical system and a number of ancillary variables. The system can further embed the polynomial formula on a hardware-based solver configured to perform optimization using the polynomial formula as an objective function to obtain a diagnostic vector used for explaining faults in the physical system.

Abstract: A method of manufacturing an integrated circuit device includes alternately stacking sacrificial semiconductor layers and channel layers on a substrate to form a stack structure, forming source regions and drain regions on both sides of the stack structure, forming a gate space between the channel layers by removing the sacrificial semiconductor layers, forming the channel layers to be spaced apart from each other in a perpendicular direction to the substrate, performing a plasma treatment of boron trichloride (BCL3) on the channel layers, forming gate dielectric layers on the channel layers on which the plasma treatment of boron trichloride (BCL3) is performed, and forming gate layers covering the gate dielectric layers in the gate space.