Patents Assigned to Research
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Patent number: 11771905Abstract: This document describes methods and materials for mapping and modulating repolarization. For example, this document relates to methods and devices for mapping and modulating repolarization to target atrial and ventricular arrhythmias to deliver electrical stimulation pacing, ablation and/or electroporation.Type: GrantFiled: April 7, 2021Date of Patent: October 3, 2023Assignee: Mayo Foundation for Medical Education & ResearchInventors: Christopher J. McLeod, Samuel J. Asirvatham
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Patent number: 11771412Abstract: An eyelid flipper tool is used to flip a patient's eyelid to gain access to the patient's meibomian gland lands and gland openings. The eyelid flipper tool has a concave end and a convex end connected by a center section. The concave end has a concave edge with a concave end width, a concave radius, and a curvature. The convex end of the eyelid flipper tool has a convex edge with a convex end up with, a convex end radius, and a curvature. The radii of the concave end and the convex end and the curvature of the ends are dimensioned to conform to the curvature of the eyelids or the globe of a patient's eye.Type: GrantFiled: November 8, 2017Date of Patent: October 3, 2023Assignee: University of Iowa Research FoundationInventor: Christine Sindt
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Patent number: 11773181Abstract: Provided are survivin specific antibodies, nucleic acids encoding the antibodies and methods for treating tumors comprising survivin-expressing cells by administration of the antibodies. The antibody compositions were found to be effective in inhibiting the growth of tumors.Type: GrantFiled: August 11, 2020Date of Patent: October 3, 2023Assignee: Health Research, Inc.Inventors: Robert A. Fenstermaker, Michael J. Ciesielski
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Patent number: 11774484Abstract: A wire voltage measurement method includes: acquiring a first corresponding relationship of an electric field intensity of a to-be-measured wire, a voltage of the to-be-measured wire, and a perpendicular distance between an electric field sensor and the to-be-measured wire; measuring at least four initial electric field intensities in an electric field sensitive direction through the at least four electric field sensors, and acquiring distances among the four electric field sensors along the straight line; calculating a second corresponding relationship of the voltage of the to-be-measured wire and an external interference electric field intensity in the electric field sensitive direction according to the four initial electric field intensities, the distances among the four electric field sensors along the straight line, the first corresponding relationship, and a spatial position relationship of the at least four electric field sensors; calculating the voltage of the to-be-measured wire according to the secoType: GrantFiled: July 1, 2022Date of Patent: October 3, 2023Assignee: Digital Grid Research Inst., China South Pwr GridInventors: Peng Li, Bing Tian, Qiancheng Lv, Zhenheng Xu, Xu Yin, Renze Chen, Shaoxiong Nie, Zejie Tan, Zhiming Wang, Licheng Li
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Patent number: 11771761Abstract: Quil-A chitosan spherical nanostructure complexes as well as methods of making and using such complexes are disclosed herein. Also provided are Quil-A chitosan spherical nanostrucutres loaded with one or more RNA, DNA, or protein payload molecules as well as methods of making and using such loaded complexes.Type: GrantFiled: June 12, 2020Date of Patent: October 3, 2023Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Adel M. Talaat, Shaswath Chandrasekar
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Patent number: 11772090Abstract: Disclosed are a low-temperature de-NOx catalyst using a ceria-alumina complex support, and a method of manufacturing the same. According to the present invention, provided is a low-temperature de-NOx catalyst using a ceria-alumina complex support, manufactured by impregnating noble metal and metal oxides into a ceria-alumina complex support synthesized by treating a ceria precursor and an alumina precursor in a predetermined mass ratio by a co-precipitation method.Type: GrantFiled: August 26, 2020Date of Patent: October 3, 2023Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Kwan Young Lee, Ki Bong Lee, Hyun Wook Kim
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Patent number: 11776867Abstract: A chip package including a heat-dissipating device, a first thermal interface material layer disposed on the heat-dissipating device, a patterned circuit layer disposed on the first thermal interface material layer, a chip disposed on the patterned circuit layer and electrically connected to the patterned circuit layer, and an insulating encapsulant covering the chip, the patterned circuit layer, and the first thermal interface material layer is provided. The first thermal interface material layer has a thickness between 100 ?m and 300 ?m. The first thermal interface material layer is located between the patterned circuit layer and the heat-dissipating device.Type: GrantFiled: June 14, 2022Date of Patent: October 3, 2023Assignee: Industrial Technology Research InstituteInventors: Kuo-Shu Kao, Tao-Chih Chang, Wen-Chih Chen, Tai-Jyun Yu, Po-Kai Chiu, Yen-Ting Lin, Wei-Kuo Han
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Patent number: 11771321Abstract: An exemplary system, method, and computer-accessible medium for generating an image(s) of an three-dimensional anatomical flow map(s) can include receiving an optical coherence tomography (“OCT”) signal(s), splitting the OCT signal(s) into a plurality of subspectra, averaging the plurality of subspectra, and generating the image(s) of the three-dimensional anatomical flow map(s) based on the averaged subspectra. The OCT signal(s) can be a swept-source OCT signal. The OCT signal(s) can be split into the subspectra based on a Hamming window. The Hamming distance window can be optimized to minimize a nearest side lobe for each of the subspectra. A position of at least one of the subspectra can be shifted prior to averaging the subspectra. The position of all but one of the subspectra can be shifted prior to averaging the subspectra.Type: GrantFiled: October 12, 2018Date of Patent: October 3, 2023Assignee: The Research Foundation for SUNYInventors: Yingtian Pan, Wei Chen, Congwu Du
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Patent number: 11771514Abstract: Containers and methods protect surgically-removed tissue such as cranial bone flaps for limited times during surgery. In some cases, tissue protected in such a container can be returned to the patient, lessening the need for synthetic, allographic, or xenographic alternatives. A container may include a frame defining a plurality of retention compartments, each retention compartment having an orientation and comprising sidewalls supported by the frame, wherein the sidewalls define a rim for each retention compartment in the plurality of retention compartments, wherein the orientation of a first retention compartment in the plurality of retention compartments differs from the orientation of a second retention compartment in the plurality of retention compartments.Type: GrantFiled: August 24, 2020Date of Patent: October 3, 2023Assignee: Clinical Biotechnology Research Institute at RSFHInventors: Brian G. Cuddy, Byron N. Bailey, Andrea H. Marshall, Jill N. Nichols
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Patent number: 11773435Abstract: A method for capturing ancient DNA of a wooden cultural relic, sequentially includes the following steps: sampling, removing exogenous DNA contamination on the inner part and the outer surface of a sample, and effectively obtaining the ancient DNA of the wooden cultural relic through vacuum freeze-drying dehydration, sample grinding, rinsing, cell lysis, DNA genome enrichment and hybridization and capturing. The method focuses on precise capture of the ancient DNA of the wood cells of the wood cultural relic, not only breaks through the problem that effective acquisition of the DNA of the wood cultural relic is difficult to realize by a conventional wood DNA extraction method, but also provides possibility for analysis and utilization of the ancient DNA with typical characteristics of serious exogenous contamination, low DNA content, high degradation, extensive damage and the like.Type: GrantFiled: February 20, 2023Date of Patent: October 3, 2023Assignee: RESEARCH INSTITUTE OF WOOD INDUSTRY, CHINESE ACADEMY OF FORESTRYInventors: Lichao Jiao, Yafang Yin, Yang Lu, Juan Guo, Yu Guo, Tuo He, Lingyu Ma
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Patent number: 11773808Abstract: A thrust panel may include a propellant socket formed to accommodate a plurality of propellants and a combustion chamber that communicates with the propellant socket.Type: GrantFiled: March 28, 2022Date of Patent: October 3, 2023Assignee: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATIONInventors: Jeongrak Lee, Anna Lee, Eunji Lee, Youngbin Son, Hanseong Jo, Seonghyeon Kim
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Patent number: 11773401Abstract: A method of decreasing conversion of nicotine to nornicotine is provided herein. The methods includes administering at least one basic region/leucine zipper (bZIP) type transcription factor inhibitor to an organism in need thereof. Also provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a bZIP type transcription factor binding site on a promoter of a nicotine N-demethylase (NND). Further provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a plant genome to knockout at least one bZIP type transcription factor.Type: GrantFiled: December 6, 2018Date of Patent: October 3, 2023Assignees: University of Kentucky Research Foundation, R.J. Reynolds Tobacco CompanyInventors: Ling Yuan, Sanjay K. Singh, Sitakanta Pattanaik, Darlene Madeline Lawson
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Patent number: 11771371Abstract: Eyewear apparatus includes dry electrophysiological electrodes and, optionally, other physiological and/or environmental sensors to measure signals such as EOG and ECG from the head of a subject. Methods of use of such apparatus to provide fitness, health, or other measured or derived, estimated, or predicted metrics are also disclosed.Type: GrantFiled: February 28, 2022Date of Patent: October 3, 2023Assignee: Orbital Research Inc.Inventors: Frederick J. Lisy, Anthony Opperman, David D. Dashevsky
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Patent number: 11774677Abstract: A fiber optic cable assembly includes first and second cable sections each having a jacket, at least one optical fiber, and multiple strength members. An intermediate cable section includes at least one splice joint as well as bundled sections of strength members of the cable sections formed into bundled sections that overlap and are adhered together. As adhered, the bundled strength members are shorter than the at least one spliced optical fiber in the intermediate section to ensure that the strength members bear tensile loads. A fabrication method includes binding unjacketed segments of strength members of two cable sections into bundled sections of strength members, fusion splicing ends of optical fibers, polymerically overcoating at least one splice joint, and adhering the bundled sections of strength members in an overlapping arrangement. An apparatus for thermoplastically coating cable assembly portions includes a trough for molten thermoplastic material, and a lateral insertion slot defined therein.Type: GrantFiled: May 18, 2022Date of Patent: October 3, 2023Assignee: Corning Research & Development CorporationInventor: Qi Wu
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Patent number: 11778839Abstract: Provided is a perovskite film including crystal grains with a crystalline structure of [A][B][X]3.n[C], wherein [A], [B], [X], [C] and n are as defined in the specification. The present disclosure further provides a precursor composition of perovskite film, method for producing of perovskite film, and semiconductor element including such films, as described above. With the optimal lattice arrangement, the perovskite film shows the effects of small surface roughness, and the semiconductor element thereof can thus achieve high efficiency and stability even with large area of film formation, thereby indeed having prospect of the application.Type: GrantFiled: December 15, 2020Date of Patent: October 3, 2023Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Kuo-Wei Huang, Yung-Liang Tung, Jung-Pin Chiou, Pei-Ting Chiu, Shih-Hsiung Wu
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Patent number: 11771662Abstract: Provided herein are treatments for reducing pain in dogs. The treatments generally comprise a combination of an opioid compound, such as methadone, and an azole compound, such as fluconazole. The treatments may further comprise an opioid abuse deterrent that advantageously inhibits opioid effects in humans while maintaining desirable analgesic effects in dogs. Additionally, the treatments provided herein avoid the undesirable side effects of prior art opioid treatments for dogs. The treatments may be administered as separate doses or in a single formulation product for improved compliance. The treatments have wide use potential in dogs from perioperative patients to inpatients and outpatients and may be used, for example, for sedation in minor procedures, analgesia, and decreasing temperature in canine patients.Type: GrantFiled: September 5, 2018Date of Patent: October 3, 2023Assignee: Kansas State University Research FoundationInventors: Stanley KuKanich, Katherine KuKanich, Charles W. Locuson, David Rankin
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Patent number: 11773146Abstract: As disclosed herein, stapled peptides targeting the interaction interface between proteins that maintain the integrity of Wiskott-Aldrich syndrome protein family member 3 (WASF3) leads to destabilization of WASF3 and suppression of invasion. Disclosed are stapled peptides that inhibit the binding of Cytoplasmic FMR1-interacting protein 1 (CYFIP1) to either WASF3 or NCK-associated protein (NCKAP1). Also disclosed are methods for treating or suppressing invasion and metastasis of a cancer in a subject that involve administering to the subject a therapeutically effective amount of a stapled peptide disclosed herein.Type: GrantFiled: September 25, 2020Date of Patent: October 3, 2023Assignees: University of Georgia Research Foundation, Inc., Augusta University Research InstituteInventors: Eileen J. Kennedy, John Cowell
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Patent number: 11774912Abstract: A device is for fastening a back on a middle of a watch. The back has a shoulder forming a cover arranged to cover entirely partly with the middle and a body arranged to rest in the middle. The device includes at least one pin integral with the middle, a seal mounted between the back and the middle. The back includes, near its periphery, at least one groove, the pin being arranged to slide in the groove between a first position, called the insertion position in which the back is free, and a second position called locking position in which the back is locked and positioned angularly relative to the middle. The groove includes at least one bump to form a hard point and increase the torque when the pin passes through the bump.Type: GrantFiled: July 14, 2021Date of Patent: October 3, 2023Assignee: The Swatch Group Research and Development LtdInventors: Joël Allimann, Benjamin Chartrel
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Patent number: 11772264Abstract: The present disclosure discloses a neural network adaptive tracking control method for joint robots, which proposes two schemes: robust adaptive control and neural adaptive control, comprising the following steps: 1) establishing a joint robot system model; 2) establishing a state space expression and an error definition when taking into consideration both the drive failure and actuator saturation of the joint robot system; 3) designing a PID controller and updating algorithms of the joint robot system; and 4) using the designed PID controller and updating algorithms to realize the control of the trajectory motion of the joint robot. The present disclosure may solve the following technical problems at the same time: the drive saturation and coupling effect in the joint system, processing parameter uncertainty and non-parametric uncertainty, execution failure handling during the system operation, compensation for non-vanishing interference, and the like.Type: GrantFiled: March 24, 2021Date of Patent: October 3, 2023Assignee: Dibi (Chongqing) Intelligent Technology Research Institute Co., Ltd.Inventors: Yongduan Song, Huan Liu, Junfeng Lai, Ziqiang Jiang, Jie Zhang, Huan Chen, Li Huang, Congyi Zhang, Yingrui Chen, Yating Yang, Chunxu Ren, Han Bao, Kuilong Yang, Ge Song, Bowen Zhang, Hong Long
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Patent number: 11776369Abstract: Systems and methods of non-line-of-sight passive detection and integrated early warning of an unmanned aerial system by a plurality of acoustic sensors are described. In some embodiments, the plurality of acoustic sensors is positioned within an intra-netted array in depth according to at least one of a terrain, terrain features, or man-made objects or structures. The acoustic sensors are capable of detecting and tracking unmanned aerial systems in non-line-of-sight environments. In some embodiments, the acoustic sensors may be in communication with internal electro-optical components or other external sensors, with orthogonal signal data then transmitted to remote observation stations for correlation, threat determination and if required, mitigation. The unmanned aerial systems may be classified by type and a threat level associated with the unmanned aerial system may be determined.Type: GrantFiled: June 4, 2021Date of Patent: October 3, 2023Assignee: Applied Research Associates, Inc.Inventors: Robert M. Serino, Mark J. McKenna, John Haas