Abstract: A dynamic interference lithography (DIL) device is provided. The device includes a laser source configured for providing a laser beam, a substrate stage configured for mounting a substrate, an at least partially convex curved mirror, and a spatial filter configured to divide the laser beam into a first beam portion directed towards the at least partially convex curved mirror and a second beam portion directed towards the substrate. The first beam portion is reflected by the at least partially convex curved mirror towards the substrate to form an interference pattern on the substrate.
Type:
Application
Filed:
March 3, 2022
Publication date:
September 8, 2022
Applicant:
Rutgers, The State University of New Jersey
Abstract: Al2O3— rich compositions with desirable hardness and crack resistance for various functional applications. Also disclosed is a method of manufacturing the composition into various dimensions and shapes under a temperature much lower than in conventional methods.
Type:
Grant
Filed:
October 9, 2018
Date of Patent:
September 6, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: Computer vision systems and methods for real-time localization of a needle in an ultrasound video are provided. The method includes a step of receiving at a processor a plurality of frames from the ultrasound video. The method also includes the step of identifying by the processor one of the plurality of frames as a background image and a frame adjacent to the background image as a current image. The method further includes the step of performing by the processor a bitwise complement operation on the background image to generate a complement image. Moreover, the method includes the step of performing by the processor a pointwise logical AND operation on the complement image and the current image to identify the location of the needle.
Type:
Grant
Filed:
August 13, 2019
Date of Patent:
August 30, 2022
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Cosmas Mwikirize, John L. Nosher, Ilker Hacihaliloglu
Abstract: The invention provides for systems, methods, and compositions for targeting nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a novel RNA-targeting CRISPR effector protein and at least one targeting nucleic acid component like a guide RNA.
Type:
Grant
Filed:
December 16, 2017
Date of Patent:
August 23, 2022
Assignees:
The Broad Institute, Inc., Massachusetts Institute of Technology, President and Fellows of Harvard College, Rutgers, The State University of New Jersey, Skolkovo Institute of Science and Technology, The United States of America, as represented by the Secretary, Department of Health and Human Services
Inventors:
Konstantin Severinov, Feng Zhang, Yuri I. Wolf, Sergey Shmakov, Ekaterina Semenova, Leonid Minakhin, Kira S. Makarova, Eugene Koonin, Silvana Konermann, Julia Joung, Jonathan S. Gootenberg, Omar O. Abudayyeh, Eric S. Lander
Abstract: A system includes a device that is disposed within an environment and is adapted to communicate over a radio frequency communication link. The system also includes a wireless access point disposed within the environment, including a wireless transceiver in communication with the device over a radio frequency communication link using a plurality of channels, and recording a channel state information data set for the radio frequency communication link. The system also includes a monitoring device including a memory storing a plurality of activity profiles, each of which includes an activity and a channel state information profile corresponding to the activity, and a processor receiving, from the wireless access point, the channel state information data set and determining, based on a comparison of the channel state information data set to the channel state information profile of each of the plurality of activity profiles, the activity of the person in the environment.
Type:
Grant
Filed:
March 31, 2021
Date of Patent:
August 23, 2022
Assignees:
THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY, RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Yingying Chen, Jie Yang, Yan Wang, Jian Liu, Marco Gruteser
Abstract: Cystine analogs that improve the solubility of L-cystine in urine for treatment of cystinuria and which have the structure: and pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein each R and R? pair are independently selected from (i) or (ii); (i) R and R? are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alcohol, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocyclic, and substituted or unsubstituted heteroaryl, or (ii) R and R? together form a substituted or unsubstituted heterocyclic ring structure, or a substituted or unsubstituted heteroaryl ring structure; X is hydrogen, or an alkyl; and Y is O or S.
Type:
Grant
Filed:
October 12, 2020
Date of Patent:
August 23, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: A biomimetic composite material includes a bioactive cement material, an autologous dentin matrix, and an inorganic nano-reinforcement material. A dental implant includes a body including a biomimetic composite material, wherein the biomimetic composite material includes a bioactive cement material, an autologous dentin matrix, and an inorganic nano-reinforcement material.
Type:
Grant
Filed:
February 14, 2020
Date of Patent:
August 9, 2022
Assignee:
Rutgers, The State University of New Jersey
Abstract: Novel radioactive iodide molecular traps, in which one or more metal atoms are functionalized by coordinating to an amine containing two or more nitrogens, and methods of using the molecular traps to capture radioactive iodide.
Type:
Grant
Filed:
December 29, 2017
Date of Patent:
August 9, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: The invention provides methods and compositions that are useful for treating allergic diseases, bacterial infections, fungal infections, viral infections, mastocytosis, mast cell-mediated inflammation and parasite infections (e.g., helminth infections).
Type:
Grant
Filed:
July 28, 2020
Date of Patent:
August 9, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: This patent document discloses a method for instrument calibration. In particular, the method can be applied to reduction of random errors by averaging fitting equation coefficients.
Type:
Application
Filed:
January 20, 2022
Publication date:
August 4, 2022
Applicant:
Rutgers, The State University of New Jersey
Abstract: The present invention provides novel methods of diagnosing and determining treatment strategies for Lyme disease and other tick-borne illnesses.
Type:
Application
Filed:
April 6, 2022
Publication date:
July 28, 2022
Applicant:
Rutgers, The State University of New Jersey
Abstract: A system for diagnosing a neurological disorder, Parkinson's Disease, and a comorbid mental health condition, major depressive disorder is provided. The system comprises a smart device and a device including a memory and a processor. The smart device allows a participant to perform a cognitive task and the device receives data collected from the smart device in connection with the cognitive task performed by the participant. The device determines whether the participant has Parkinson's Disease based on the data collected and via a classification algorithm. If the participant has Parkinson's Disease, the device determines whether the participant has comorbid major depressive disorder.
Type:
Application
Filed:
April 8, 2022
Publication date:
July 21, 2022
Applicants:
Rutgers, The State University of New Jersey, Al-Quds University
Abstract: The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.
Type:
Application
Filed:
April 22, 2020
Publication date:
July 21, 2022
Applicant:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Purnima BHANOT, David J. AUGERI, John A. GILLERAN, Raheel FONDEKAR
Abstract: The invention provides seed and plants of catnip hybrid ‘CR9’. The invention thus relates to the plants, seeds, and tissue cultures of catnip hybrid ‘CR9’, and to methods for producing a catnip plant of the present invention by crossing such plants with themselves or with another catnip plant, such as a plant of another genotype, variety, or cultivar. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants.
Type:
Grant
Filed:
November 1, 2019
Date of Patent:
July 19, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: An image processing neural network system includes a base net of at least one convolutional layer and at least one pooling layer; and a scenario block layer. The scenario block layer performs scene classification and generates a dictionary of scenarios and a vector of scenario encoding coefficients to output a probabilistic scene class assignment and the vector of scenario encoding coefficients. The vector of scenario encoding coefficients corresponds to reasoning for the scene classification.
Type:
Grant
Filed:
February 13, 2020
Date of Patent:
July 12, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: The invention describes a method of generating antibodies to a mixture of peptidogenic proteins wherein the peptidogenic protein has altered conformational dynamics as compared to a starting protein and wherein the peptidogenic protein has a similar conformation to the starting protein. The peptidogenic proteins can be used to induce an immune response, which can lead to the generation of antibodies and/or can be used to vaccinate a mammal.
Type:
Grant
Filed:
August 18, 2016
Date of Patent:
July 12, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Abstract: Disclosed are the methods for fabricating holey graphene nanoplatelets using microwave irradiation to treat a dry graphite powder. In particular, the methods can be used to treat graphite intercalation compounds either with or without partial oxidation to obtain holey graphene nanoplatelets with predetermined hole size, hole edge shape, thickness and lateral dimension. The method does not involve any toxic reagents or metal-containing compounds, and without generating toxic byproducts, thus enabling a variety of eco-friendly applications.
Type:
Grant
Filed:
June 14, 2018
Date of Patent:
July 5, 2022
Assignee:
RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Inventors:
Huixin He, Keerthi Savaram, Qingdong Li