Abstract: A nuclear magnetic resonance (NMR) method for detecting hydrogen peroxide includes providing a liquid sample in a static magnetic field; stimulating a spin signal in the sample by exciting the sample with a first electromagnetic pulse having a frequency corresponding to the hydrogen NMR frequency in the static magnetic field; waiting for a first time period; refocusing the spin signal in the sample for a first number of times by a series of second electromagnetic pulses having a frequency corresponding to the hydrogen NMR frequency in the static magnetic field, said second electromagnetic pulses being separated by a first echo time, while sampling a first train of spin signals in between the second electromagnetic pulses; and refocusing the spin signal in the sample for a second number of times by a series of third electromagnetic pulses having a frequency corresponding to the hydrogen frequency in the static magnetic field, said third electromagnetic pulses being separated by a second echo time while samplin

Abstract: An apparatus for providing a sensitive volume for single-sided NMR includes: (i) at least one first permanent magnet for providing a first magnetic field at the sensitive volume; and (ii) at least one of the following means for superimposing at least one second magnetic field for homogenizing the first magnetic field in the sensitive volume: (A) at least one shim magnet, (B) at least one pair of shim magnets, and (C) at least one electrical conductor being connectable to an electric current source. The at least one second magnetic field is adjusted such that the magnetic field homogeneity in the sensitive volume is corresponding to a line width of hydrogen (1H) of less than 10 ppm.

Abstract: A magnet arrangement includes (a) a first and a second head ring magnet each having a substantially circular geometry with respect to a centre axis and (b) a central ring magnet having a substantially circular geometry with respect to a centre axis. The central ring magnet is disposed between the first and second head ring magnet in direction of the centre axis. At least one of the magnets includes a first number of first magnets having at least one trapezoidal cross section and a second number of second magnets having at least one rectangular cross section. The second magnets are disposed in between the first magnets in circumferential direction. With this geometrical arrangement, magnets having a trapezoidal cross section include a guidance for a magnet having a rectangular cross section allowing the movements in radial direction of these last magnets.

Abstract: The invention relates to novel composite materials, which comprise at least one thermoplastic organic polymer matrix and at least one hydraulic binder distributed in the polymer matrix. The invention also relates to a process for the preparation of such composite materials and to the use of these composite materials in textile materials. The composite materials comprise at least one thermoplastic organic polymer matrix and at least one hydraulic binder distributed in the polymer matrix, where the thermoplastic polymer matrix consists predominantly, i.e. to at least 60% by weight, in particular to at least 70% by weight, preferentially to at least 80% by weight, and especially preferred to at least 90% by weight, of at least one polymer, which is water-soluble or which under alkaline conditions is converted into a water-soluble polymer.

Abstract: The invention relates to a microtiter plate and use thereof for conducting fermentation under fed-batch conditions. In order to produce a microtiter plate which permits screening under fed-batch conditions, the invention proposes that the cavities (2) of the microtiter plate according to the invention be filled with a culturing fluid and nutrient solution and be designed in such a way that each of the cavities (2) of the microtiter plate which is filled with nutrient solution is connected by a channel (4) to at least one other further cavity (3) of the microtiter plate which is filled with a culturing fluid. A diffusion barrier (13) arranged in the material permeable channel (4) controls the kinetics of the material transfer of nutrients from the cavity containing the nutrient solution to the cavities containing the culturing fluid.

Abstract: The present invention relates to a process for the preparation of composites from thermoplastic polymers and (semi)metal oxides, in particular silicon dioxide, wherein at least a part of the (semi)metal oxides is dispersed in the polymers in nanodispersed manner (nanocomposites). The invention relates to the composites obtainable by this process and their processing to give molded articles.

Abstract: In order to develop and optimize metering strategies for fed-batch fermentations in two or more reaction vessels, release systems containing nutrients are attached to the inner surfaces of the reaction vessels in areas that will come into contact with culture liquid placed in the vessels.

Abstract: S-Adenosyl-L-methionine analogs of formula (I) wherein R comprises a carbon-carbon double bond, carbon-oxygen double bond, carbon-sulfur double bond, carbon-nitrogen double bond, a carbon-carbon triple bond, carbon-nitrogen triple bond or an aromatic carbocyclic or heterocyclic system in ?-position to the sulfonium center, X— is an organic or inorganic anion carrying one or more negative charges, Z is —CR1R2—, —O—, —S— or —NR3— and R1, R2 and R3 are independently selected from H, D and C1-C12 alkyl. Also disclosed are complexes of the compound with a methyltransferase, pharmaceutical compositions comprising the same, methods for modifying biomolecule using the compound, and methods for detecting sequences specific methylation of biomolecules using the compound.

Abstract: The invention relates to polypeptides of amino acid sequence SEQ ID NO: 1 according to formula (1), the use thereof for producing a medicament, and medicaments for the treatment of diseases related to monocyte recruitment.

Abstract: Disclosed are reactive cyclic carbonates and ureas of formula (I) or (II), wherein R and X have the meaning indicated in the description. Said carbonates and ureas allow functional groups to be specifically introduced into biomolecules, polymers, and surfaces in mild conditions.

Abstract: In order to improve a surgical holding device for holding a surgical instrument, with a frame, with a first linkage comprising at least two links, which articulatedly connects the frame to a first articulation point associated with the instrument, and with a second linkage comprising at least two links, which articulatedly connects the frame to a second articulation point associated with the instrument, so that a large range of action of the surgical instrument held by the holding device is adjustable as simply as possible, it is proposed that the links of the first linkage be mounted for pivotal movement about pivot axes relative to one another and relative to the frame, and that the pivot axes extend parallel to one another.

Abstract: The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular group wherein as a result of the administration of the composition to the human or animal body an active complex having a molecular weight of 25,000 Daltons or greater is present in the human or animal circulatory system. The analogue is hepatoselective when administered to the circulatory system. Preferably the analogue is an insulin analogue comprising an insulin or functional equivalent thereof covalently linked to the pendant molecular group wherein the active complex is an insulin complex. Such an insulin analogue may be used in a method of insulin replacement therapy.

Abstract: A porous, flow-through molded body, designed specifically for use in the removal of diesel soot particles from the exhaust gas of diesel engines. It includes a reciprocally closed honeycombed body made of silicon carbide and possessing the following features.wall thickness: 1.25.+-.0.5 mm;porosity: 55 to 60%;average pore diameter: 25 to 70 .mu.m;specific permeability: 20 to 100 nPm.In the production method, a starting powder of silicon or a mixture of silicon with portions of silicon carbide and/or carbon is combined with an organic binding agent that can be coked and molded into a green body. This is then subjected to a coking fire in an inert-gas atmosphere; the molded body obtained in this manner is then heated in the presence of nitrogen or a nitrogenous inert gas to a temperature where free silicon is converted with the carbon, in a reaction firing, to silicon carbide. Additionally, a recrystallization firing at greater than 2000.degree. C. is implemented.