Abstract: Compounds of formula I ##STR1## wherein A, B, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the description, are useful for the treatment of conditions where prevention or delay of progressive atrophy of the optic nerve is desirable.
Abstract: There is provided a method for protecting crop plants from phytotoxic injury caused by a chloroacetamide herbicide by co-applying a non-phytotoxic, conditioning effective amount of a benzothiadiazinone derivative. The method is particularly effective in protecting dry edible beans from phytotoxicity when dimethenamid is applied postemergence.
Abstract: This invention relates to novel biopesticidal compositions comprising an active insecticidal ingredient selected from insecticidal bacteria and viruses such as B. thuringiensis crystal protein or spores or mixtures thereof and baculoviruses such as nuclear polyhedrosis viruses, granulosis viruses and non-occluded viruses; a polymer; and an inorganic light blocking agent wherein the light blocking agent protects the active ingredient from both ultraviolet light and sunlight and the polymer forms a matrix in which the active ingredient and light blocking agent are dispersed therein. Methods for producing the biopesticidal compositions and methods of controlling insects are also included within the scope of the invention.
Type:
Grant
Filed:
June 12, 1996
Date of Patent:
December 22, 1998
Assignee:
Sandoz Ltd.
Inventors:
Jeffrey D. Fowler, Benjamin E. Feinstein
Abstract: The present invention relates to a novel sporulation gene isolated from B. thuringiensis, and a DNA segment comprising the nucleic acid sequences encoding the gene and DNA sequences encoding crystal toxin proteins wherein said DNA segment is stably integrated into a B. thuringiensis host by homologous recombination. The invention further relates to a DNA segment wherein the sporulation gene is mutated thereby rendering an oligosporogenic or asporogenic transformed B. thuringiensis as a result of stable integration of the DNA segment into the Bacillus thuringiensis chromosome by homologous recombination.
Type:
Grant
Filed:
July 15, 1996
Date of Patent:
October 27, 1998
Assignee:
Sandoz Ltd.
Inventors:
Mitra Shahabi Reynoso, Sue S. Kalman, Nicole H. Cooper, Takashi Yamamoto
Abstract: Substituted aryl or heteroaryl in particular benzoyl bicycloalkanediones and related compounds, intermediates therefor, synthesis thereof, and the use of said diones for the control of weeds.
Abstract: This invention relates to novel screening methods for identifying compounds that specifically inhibit a biosynthetic pathway in plants. Enzymes which are specifically affected by the novel screening method include plant purine biosynthetic pathway enzymes and particularly the enzymes involved in the conversion of inosine monophosphate to adenosine monophosphate and inosine monophosphate to guanosine monophosphate. Further the invention relates to compositions and method of use comprising herbicidally effective amounts of the identified compounds.
Type:
Grant
Filed:
November 21, 1996
Date of Patent:
July 14, 1998
Assignee:
Sandoz Ltd.
Inventors:
Venkiteswaran Subramanian, Anne G. Toschi
Abstract: The invention provides a process for the preparation of a compound of the general formula (I): ##STR1## wherein X, Y and R.sup.1 to R.sup.7 are as defined. In the process, the olefinic analog of the compound of general formula (I) is treated with a halogen-bearing compound in the presence of metallic zinc.
Type:
Grant
Filed:
May 19, 1995
Date of Patent:
June 23, 1998
Assignee:
Sandoz Ltd.
Inventors:
Patrick Jelf Crowley, Christopher John Urch, Paul Anthony Worthington
Abstract: Co-application of auxin agonist herbicides such as dicamba and amino acid synthesis inhibitor herbicides such as ALS inhibitor herbicides reduces the incidence of phytotoxic effects, particularly in grassy crops.
Type:
Grant
Filed:
September 15, 1994
Date of Patent:
April 14, 1998
Assignee:
Sandoz Ltd.
Inventors:
Mark C. Boyles, John M. Fenderson, Bart Brinkman
Abstract: The present invention provides, inter allia, a B.t. hybrid toxin fragment comprising at its C-terminal domain III of a first Cry protein or a part of the domain or a protein substantially similar to the domain, with the proviso that the N-terminal region of the fragment is the N-terminal region of a second Cry protein or a part of the region or a protein substantially similar to the region.
Type:
Grant
Filed:
February 21, 1996
Date of Patent:
April 7, 1998
Assignee:
Sandoz Ltd.
Inventors:
Hendrik Jan Bosch, Willem Johannes Stiekema
Abstract: A novel insecticidal protein isolated from Bacillus thuringiensis var. galleria is described and its DNA sequence is given. This protein, called CryIC(b), is toxic to Lepidoptera, including Spodoptera.