Patents Assigned to Sandoz Ltd.
  • Patent number: 6300362
    Abstract: The invention relates to the use of certain acid donors as stabilizers in pharmaceutical compositions, and to the stabilized pharmaceutical compositions resulting therefrom.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 9, 2001
    Assignee: Novartis AG (formerly Sandoz Ltd.)
    Inventors: Richard V. Vivilecchia, Bruce A. Ross
  • Patent number: 5990046
    Abstract: Co-application of dimethenamid with diketone or triketone herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 23, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5955468
    Abstract: Compounds of formula I ##STR1## wherein A, B, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the description, are useful for the treatment of conditions where prevention or delay of progressive atrophy of the optic nerve is desirable.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 21, 1999
    Assignee: Sandoz Ltd.
    Inventor: Rudolf Markstein
  • Patent number: 5928996
    Abstract: Co-application of dimethenamid with dinitroaniline herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 18, 1997
    Date of Patent: July 27, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christopher Schumm, Walter Van Loocke
  • Patent number: 5922643
    Abstract: Co-application of dimethenamid with aryloxyphenoxy herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: July 13, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5905059
    Abstract: Co-application of dimethenamid with pyridate and other herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: May 18, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5888936
    Abstract: Co-application of dimethenamid with other herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: March 30, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5888935
    Abstract: Co-application of dimethenamid with other herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: March 30, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5885933
    Abstract: Co-application of dimethenamid with other herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: March 23, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5883046
    Abstract: Microencapsulated agrochemicals based on crosslinked polyester polymers particularly suited to rapidly leaching herbicides.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: March 16, 1999
    Assignee: Sandoz Ltd.
    Inventor: George F. Luteri
  • Patent number: 5877115
    Abstract: The present invention relates to co-application of dimethenamid with at least one other herbicide to provide improved herbicidal activity.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: March 2, 1999
    Assignee: Sandoz Ltd.
    Inventors: John M. Fenderson, William B. O'Neal, Theo Quaghebeur, Karl-Christoph Schumm, Walter Van Loocke
  • Patent number: 5854176
    Abstract: There is provided a method for protecting crop plants from phytotoxic injury caused by a chloroacetamide herbicide by co-applying a non-phytotoxic, conditioning effective amount of a benzothiadiazinone derivative. The method is particularly effective in protecting dry edible beans from phytotoxicity when dimethenamid is applied postemergence.
    Type: Grant
    Filed: March 7, 1997
    Date of Patent: December 29, 1998
    Assignee: Sandoz Ltd.
    Inventor: John M. Foster
  • Patent number: 5851545
    Abstract: This invention relates to novel biopesticidal compositions comprising an active insecticidal ingredient selected from insecticidal bacteria and viruses such as B. thuringiensis crystal protein or spores or mixtures thereof and baculoviruses such as nuclear polyhedrosis viruses, granulosis viruses and non-occluded viruses; a polymer; and an inorganic light blocking agent wherein the light blocking agent protects the active ingredient from both ultraviolet light and sunlight and the polymer forms a matrix in which the active ingredient and light blocking agent are dispersed therein. Methods for producing the biopesticidal compositions and methods of controlling insects are also included within the scope of the invention.
    Type: Grant
    Filed: June 12, 1996
    Date of Patent: December 22, 1998
    Assignee: Sandoz Ltd.
    Inventors: Jeffrey D. Fowler, Benjamin E. Feinstein
  • Patent number: 5827515
    Abstract: The present invention relates to a novel sporulation gene isolated from B. thuringiensis, and a DNA segment comprising the nucleic acid sequences encoding the gene and DNA sequences encoding crystal toxin proteins wherein said DNA segment is stably integrated into a B. thuringiensis host by homologous recombination. The invention further relates to a DNA segment wherein the sporulation gene is mutated thereby rendering an oligosporogenic or asporogenic transformed B. thuringiensis as a result of stable integration of the DNA segment into the Bacillus thuringiensis chromosome by homologous recombination.
    Type: Grant
    Filed: July 15, 1996
    Date of Patent: October 27, 1998
    Assignee: Sandoz Ltd.
    Inventors: Mitra Shahabi Reynoso, Sue S. Kalman, Nicole H. Cooper, Takashi Yamamoto
  • Patent number: 5811569
    Abstract: The invention discloses a novel process for the preparation of a compound of formula II ##STR1## wherein R.sub.1 is C.sub.1-5 alkyl,R.sub.2 is hydrogen or C.sub.1-5 alkyl, andR.sub.3 is optionally substituted phenyl,comprising the reaction of a 4-hydroxypyrazole of formula III ##STR2## wherein R.sub.1 and R.sub.2 are as defined for formula II, with a benzylhalide of formula IVHal--CH.sub.2 --R.sub.3 (IV)wherein Hal is halogen, preferably bromine or chlorine, and R.sub.3 is as defined for formula II, in the presence of a base. The invention further comprises a novel process for the preparation of the 4-hydroxypyrazole of formula III. The compounds of formulae II and III are intermediates for highly effective systemic fungicides of the class of pyrazolyl acetic acid derivatives.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: September 22, 1998
    Assignee: Sandoz Ltd
    Inventors: Erwin Waldvogel, Eugen Eichenberger
  • Patent number: 5801120
    Abstract: Substituted aryl or heteroaryl in particular benzoyl bicycloalkanediones and related compounds, intermediates therefor, synthesis thereof, and the use of said diones for the control of weeds.
    Type: Grant
    Filed: September 22, 1989
    Date of Patent: September 1, 1998
    Assignee: Sandoz Ltd.
    Inventors: Shy-Fuh Lee, Takashi Nishizaka, Kenichi Komatsubara
  • Patent number: 5783580
    Abstract: This invention relates to compounds of formula I ##STR1## wherein R.sup.1 is C.sub.1-4 alkoxy or --NR.sup.8 R.sup.9 ;R.sup.2 is heteroaryl, heteroaryloxy or a group ##STR2## R.sup.3 is hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, cyano, nitro or halogen;R.sup.4 is hydrogen, halogen, C.sub.1-4 alkoxy or C.sub.1-4 alkyl;R.sup.5 is hydrogen or methyl;R.sup.7 is hydrogen or methyl;R.sup.8 and R.sup.9 are independently C.sub.1-4 alkyl or together C.sub.3-6 alkylene;E is C.sub.1-3 alkylene;X is CH or nitrogen; andY is OCH.sub.3, NH.sub.2, NHCH.sub.3 or N(CH.sub.3).sub.2.
    Type: Grant
    Filed: May 23, 1996
    Date of Patent: July 21, 1998
    Assignee: Sandoz, Ltd.
    Inventors: Martin Eberle, Fritz Schaub, Gerald Wayne Craig
  • Patent number: 5780253
    Abstract: This invention relates to novel screening methods for identifying compounds that specifically inhibit a biosynthetic pathway in plants. Enzymes which are specifically affected by the novel screening method include plant purine biosynthetic pathway enzymes and particularly the enzymes involved in the conversion of inosine monophosphate to adenosine monophosphate and inosine monophosphate to guanosine monophosphate. Further the invention relates to compositions and method of use comprising herbicidally effective amounts of the identified compounds.
    Type: Grant
    Filed: November 21, 1996
    Date of Patent: July 14, 1998
    Assignee: Sandoz Ltd.
    Inventors: Venkiteswaran Subramanian, Anne G. Toschi
  • Patent number: 5780254
    Abstract: This invention relates to novel screening methods for identifying compounds that specifically inhibit a metabolic target site or pathway in plants. Enzymes which are specifically affected by the novel screening method include plant purine biosynthetic pathway enzymes and particularly the enzymes involved in the conversion of IMP to AMP and the conversion of IMP to GMP. Further the invention relates to a method for screening and identifying potential novel compounds that function by the same mode of action as hydantocidin, and the compositions and method of use comprising said compounds.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: July 14, 1998
    Assignee: Sandoz Ltd
    Inventors: Daniel L. Siehl, Venkiteswaran Subramanian, Anne G. Toschi
  • Patent number: 5780626
    Abstract: Substituted 1,2 oxazine compounds having the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are independently hydrogen; C.sub.1-8 alkyl; carboxyl; C.sub.1-8 alkoxycarbonyl or optionally substituted phenyl or R.sub.1 and R.sub.2 together form a C.sub.3-6 alkylene bridge.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: July 14, 1998
    Assignee: Sandoz, Ltd
    Inventor: Shy-Fuy Lee