Patents Assigned to Sandoz Ltd.
  • Patent number: 5629048
    Abstract: A method of rapidly forming in place a cementitious structure comprising mixing a cement composition with an amount of a water soluble citrate effective to accelerate the setting of the cement in the presence of sufficient water for hydraulic setting of the cement, and delivering the resulting composition while fluid to the place for forming the cementitious structure.
    Type: Grant
    Filed: May 17, 1996
    Date of Patent: May 13, 1997
    Assignee: Sandoz Ltd.
    Inventor: Frederick D. Kinney
  • Patent number: 5627137
    Abstract: Substituted phthalides and heterocyclic phthalides and derivatives thereof which are useful as herbicides are described.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 6, 1997
    Assignee: Sandoz Ltd.
    Inventors: Richard J. Anderson, Ian S. Cloudsdale, Takeo Hokama
  • Patent number: 5627138
    Abstract: Substituted phthalides and heterocyclic phthalides and derivatives thereof which are useful as herbicides are described.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 6, 1997
    Assignee: Sandoz Ltd.
    Inventors: Richard J. Anderson, Ian S. Cloudsdale, Takeo Hokama
  • Patent number: 5626634
    Abstract: A liquid dyestuff composition comprising a solvent-soluble dyestuff and a water miscible organic solvent, the composition comprising over 25% by weight of dissolved dyestuff.
    Type: Grant
    Filed: December 2, 1994
    Date of Patent: May 6, 1997
    Assignee: Sandoz Ltd.
    Inventors: J urgen Goldmann, Bansi L. Kaul
  • Patent number: 5622982
    Abstract: The invention concerns azole compounds of formula ##STR1## wherein the substituents have various significances, in free form or salt form.They can be prepared e.g. by acylation, or by aziridine or oxazole ring opening.The compounds can be used as pharmaceuticals, especially as selective inhibitors of the 25-hydroxyvitamin D3--hydroxylases in the treatment of disorders of proliferation and differentiation in vitamin D--responsive tissues.
    Type: Grant
    Filed: May 16, 1995
    Date of Patent: April 22, 1997
    Assignee: Sandoz Ltd.
    Inventors: Ingeborg Schuster, Helmut Egger
  • Patent number: 5621148
    Abstract: (A) oligohydroxy-C.sub.3-8 -alkanes containing at least 3 hydroxy groups and (B) KOH, that contain at least 5% by weight of K.sup.+ and at least one alcoholic hydroxy group are eminently suitable as oxyalkylation catalysts, in particular for the oxyalkylation of ester group-containing substrates, before all of natural, vegetable or animal fats or oils or their modification products.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: April 15, 1997
    Assignee: Sandoz Ltd.
    Inventor: Hans-Peter Baumann
  • Patent number: 5615975
    Abstract: The present invention is a method for the detoxification and/or chemical remediation of soil contaminated with volatile organic compounds. The process comprises treating the soil with the sodium and calcium salts of naphthalene sulfonates, lignosulfonates, their derivatives and mixtures thereof. The volatile organics are then forced from the soil as the soil is more attracted to the admixture than it is to the volatile organic contaminants.
    Type: Grant
    Filed: July 14, 1995
    Date of Patent: April 1, 1997
    Assignee: Sandoz Ltd.
    Inventors: Hugh H. Wang, John Parker, Paul Przygocki, Mike Ameel
  • Patent number: 5616778
    Abstract: The compound of the formula ##STR1## having the following CIELAB values: L*=82.55a*=11.53b*=90.49C*=91.22 andH*=82.74.
    Type: Grant
    Filed: April 21, 1994
    Date of Patent: April 1, 1997
    Assignee: Sandoz Ltd.
    Inventors: J urgen Goldmann, Bansi L. Kaul
  • Patent number: 5616636
    Abstract: A composition comprising:a) a compound containing a phosphite or phosphonite group and at least one 2,2,6,6-tetraalkylpiperidinyl group, andb) a polyolefin which has been produced in the presence of a catalyst which is eitheri) a supported Zeigler catalyst orii) a metallocene catalyst,from which polyolefin the catalyst has not been removed.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: April 1, 1997
    Assignee: Sandoz Ltd.
    Inventors: Lajos Avar, Peter Staniek, Klaus Stoll, Wolf D. Habicher, Uwe Hahner
  • Patent number: 5614466
    Abstract: Co-application of auxin agonist herbicides such as dicamba and amino acid synthesis inhibitor herbicides such as ALS inhibitor herbicides reduces the incidence of phytotoxic effects, particularly in grassy crops.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: March 25, 1997
    Assignee: Sandoz Ltd.
    Inventors: Mark C. Boyles, John M. Fenderson, Bart Brinkman
  • Patent number: 5612284
    Abstract: Co-application of auxin agonist herbicides such as dicamba and amino acid synthesis inhibitor herbicides such as ALS inhibitor herbicides reduces the incidence of phytotoxic effects, particularly in grassy crops.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: March 18, 1997
    Assignee: Sandoz Ltd.
    Inventors: Mark C. Boyles, John M. Fenderson, Bart Brinkman
  • Patent number: 5612472
    Abstract: A Brassica promoter (hsp80) has been isolated which can provide for constitutive expression of heterologous genes in a wide range of tissues and organs. Various deletion mutants and hybrid promoters are described which retain activity and/or which show enhanced activity. Upstream activating sequences are described which separately and in combination can provide for constitutive gene expression. These sequences can also confer constitutive expression on heterologous, non-constitutive promoters.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: March 18, 1997
    Assignee: Sandoz Ltd.
    Inventors: Stacy L. Wilson, Karen J. Brunke
  • Patent number: 5611818
    Abstract: By reducing a sulphur dye (S) in aqueous medium with a reducing carbonyl compound in the presence of alkali metal hydroxide and optionally alkali metal (bi)sulphite at temperatures above 60.degree. C. and drying the reaction mixture, there are obtained very stable leuco sulphur dyes (L), which are practically free of sulphides and polysulphides, are readily and completely soluble in water and are usable for the dyeing of substrates dyeable with sulphur dyes, by which a disturbing development of H.sub.2 S or a disturbing inorganic sulphide occurrance in the waste water can be efficiently avoided; by spray-drying in a drying time <4 minutes as described there are obtained sulphide-free, stable leuco sulphur dyes (L) readily soluble in water and particularly suitable for sulphide-free dyeing, in particular for the dyeing of polyamidic fibrous substrates, especially of wool.
    Type: Grant
    Filed: November 22, 1993
    Date of Patent: March 18, 1997
    Assignee: Sandoz Ltd.
    Inventor: Manuel J. Domingo
  • Patent number: 5612396
    Abstract: A random copolymer in free acid or salt form having the following types and numbers of monomer units; ##STR1## in which M is hydrogen or a residue of a hydrophobic polyalkylene glycol or polysiloxane,R is an C.sub.2-6 alkylene radical,R.sub.1 is a C.sub.1-20 alkyl, C.sub.6-9 cycloalkyl or phenyl group,x,y and z are numbers from 1 to 100,m is a number from 1 to 100,n is a number from 10 to 100,with the provisos, thati) the ratio of x to (y+z) is from 1:10 to 10:1 inclusive,ii) the ratio of z:y is from 5:1 to 100:1, andiii) m+n=15-100.The copolymers are useful as additives in cementitious compositions.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 18, 1997
    Assignee: Sandoz Ltd.
    Inventors: Salvatore Valenti, Bernhard Leikauf, Akira Ohta
  • Patent number: 5609724
    Abstract: Ascospores of wood-penetrating, pitch-grading fungi of the class of Ascomycotina and Deuteromycotina, eg. Ophiostromas, may be screened to provide fungi combining the properties of good growth on non-sterile wood substrates and minimized or even enhanced brightness effects for use in pitch reduction of wood substrates, eg. logs and wood chips. A new and improved method of isolating such ascospores involving effective suspension in an oil consumable by the fungus, eg. a vegetable oil, and then treatment of the oil with a dispersing agent is also disclosed.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 11, 1997
    Assignee: Sandoz Ltd
    Inventors: Roberta L. Farrell, Yitzhak Hadar, Philip A. Wendler, Wendy Zimmerman
  • Patent number: 5609681
    Abstract: A process for modifying the slump of a concrete or mortar by the addition at different times of a water-soluble poly(alkylene oxide) and a .beta.-naphthalene sulphonate-formaldehyde condensate, a plasticizer or superplasticizer which is selected from lignosulphonates, melamine sulphonate formaldehyde condensates, carboxylates and selected styrene-maleic anhydride copolymers. The poly(alkylene oxide) is preferably partially replaced by a (hydroxy)alkyl cellulose. The process is advantageously used in shotcreting.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 11, 1997
    Assignee: Sandoz Ltd.
    Inventors: Josef F. Drs, Tom Melbye, Odd M. Tjugum, Salvatore Valenti
  • Patent number: 5608151
    Abstract: Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: March 4, 1997
    Assignee: Sandoz Ltd.
    Inventors: Kirsten Bojsen, Karsten M. Kragh, J.o slashed.rn D. Mikkelsen, Klaus K. Nielsen, John E. Nielsen
  • Patent number: 5607919
    Abstract: Anti-microbial proteins isolated from sugar beet, wherein the anti-microbial proteins exclude chitinases and glucanases. Said proteins include a pure protein selected from those depicted in SEQ ID Nos 2, 5 and 8, or a functionally equivalent analogue thereof in which one or more amino acids have been added, substituted or removed without substantially reducing the protein's anti-microbial activity, or mixtures of such proteins or analogues. A synergistic anti-fungal effect is observed if at least one of the AX proteins is combined with a WIN protein. The invention also provides recombinant DNA comprising a sequence encoding a protein according to the invention, a vector comprising said DNA and transformed plants comprising said DNA. The invention further provides an anti-microbial composition containing one or more of the said proteins, and a process for combatting fungi or bacteria which comprises exposing them to said proteins or compositions.
    Type: Grant
    Filed: October 13, 1995
    Date of Patent: March 4, 1997
    Assignee: Sandoz Ltd.
    Inventors: Kirsten Bojsen, Karsten M. Kragh, J.o slashed.rn D. Mikkelsen, Klaus K. Nielsen, John E. Nielsen
  • Patent number: 5607855
    Abstract: This invention relates to fungi having particularly desirable overall properties for reducing the pitch content of pulpwoods and pulps, and to the preparation and use of such fungi. In particular, the present invention provides a biologically pure cultures of the fungus Ophiostoma piliferum which are characterized by not only growing white or colorless and by having good growth virulence, but which also exhibit exceptional pitch degradation properties.
    Type: Grant
    Filed: June 28, 1994
    Date of Patent: March 4, 1997
    Assignee: Sandoz Ltd.
    Inventors: Wendy C. Zimmerman, Roberta L. Farrell
  • Patent number: 5602237
    Abstract: The invention provides a 1:2 metal complex in which at least one of the complexants is a polyazo compound of formula ##STR1## wherein --A.sub.1 --(CO).sub.p --OH signifies the radical of a diazo component of formula H.sub.2 N--A--(CO).sub.p --OH, in which the substituent --(CO).sub.p --OH is in ortho-position to the diazotizable amino group --NH.sub.2, --A-- is the ortho-bivalent radical and p signifies 0 or 1, or a modified derivative thereof,--X-- signifies an aromatic bivalent radical,--B.sub.1 signifies the radical of a coupling component HB, or a modified derivative thereof,m signifies 0 or 1,n signifies 0, 1 or 2and M signifies hydrogen or a cation, with the proviso that m+n=1 or 2,or a mixture of such complexes and to the use thereof as dyestuffs, in particular for the dyeing of a substrate dyeable with anionic dyes, especially of leather or pelts.
    Type: Grant
    Filed: March 29, 1995
    Date of Patent: February 11, 1997
    Assignee: Sandoz Ltd.
    Inventors: Jordi B. Barra, Jose R. Sorolla