Patents Assigned to Sandoz Ltd.
  • Hyper-sensitivity related gene
    Patent number: 5552527
    Abstract: The hsr203J gene of SEQ ID No. 1 and individual components thereof including its promoter and regulatory regions thereof, its coding region, its gene product; modifications thereto; applications of said gene, promoter region, regulatory region and coding region and modifications thereto; DNA constructs, vectors and transformed plants each comprising the gene or part thereof.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: September 3, 1996
    Assignee: Sandoz Ltd.
    Inventors: Laurence Godiard, Yves Marco, Dominique Pontier, Dominique Roby
  • Azo compounds having unsubstituted or substituted 2-phenoxycarbonylethyl groups
    Patent number: 5550218
    Abstract: Compounds of the formula ##STR1## wherein A is C.sub.1-6 alkylene, D is a diazo component radical of the triazolyl, pyrazolyl, cyano(C.sub.1-4 alkyl)-imidazolyl, 4-chlorothiazolyl, 4-chlorotheinyl-2, 3-phenyl-1,2,4-thiadiazolyl-5, isothiazolyl-5, benzoisothiazolyl-3 or 1,3,4-thiadiazolyl-5 series or the phenyl series wherein the phenyl group is free of sulfonyl groups and may be substituted, by a maximum of 3 substituents 5-nitrothiazolyl-2, ##STR2## R.sub.1a is phenyl or phenyl substituted by 1 to 4 substituents each of which is independently halo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, hydroxy, nitro, formyl, cyano, --SCN, (C.sub.1-4 alkyl)carbonyl, (C.sub.1-4 alkyl)carbonylamino, (C.sub.1-4 alkoxy)carbonyl, (C.sub.1-4 alkyl)carbonyloxy, carbamoyl, (C.sub.1-2 alkoxy)(C.sub.2-3 alkoxy)carbonyl or phenyl, andR.sub.2 -R.sub.4 and R.sub.10 -R.sub.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: August 27, 1996
    Assignee: Sandoz Ltd.
    Inventor: Ruedi Altermatt
  • Hyper-sensitivity related gene
    Patent number: 5550228
    Abstract: The hsr203J gene of SEQ ID No. 1 and individual components thereof including its promoter and regulatory regions thereof, its coding region, its gene product; modifications thereto; applications of said gene, promoter region, regulatory region and coding region and modifications thereto; DNA constructs, vectors and transformed plants each comprising the gene or part thereof.
    Type: Grant
    Filed: February 23, 1994
    Date of Patent: August 27, 1996
    Assignee: Sandoz Ltd.
    Inventors: Laurence Godiard, Yves Marco, Dominique Pontier, Dominique Roby
  • .alpha.-pyrimidinyl acrylic acid derivatives
    Patent number: 5547919
    Abstract: The invention discloses compounds of formula I ##STR1## the use of such compounds for the control of phytopathogens, composition for facilitating such use, and the preparation of the compounds of formula I.
    Type: Grant
    Filed: January 10, 1995
    Date of Patent: August 20, 1996
    Assignee: Sandoz Ltd.
    Inventors: Martin Eberle, Fritz Schaub, Gerald W. Craig
  • Cationically bridged tetrakisazo dyestuffs with variable couplers, their production and use
    Patent number: 5545724
    Abstract: The invention relates to cationically bridged tetrakisazo compounds, corresponding to formula I, ##STR1## wherein the individual symbols are defined as in claim 1, as well as residues and liquid preparations thereof. The compounds and their preparations are used for dyeing and printing hydroxy-group-containing or nitrogen-containing organic substrates by a known method. Preferred substrates are textile materials which consist of or contain cellulose, especially cotton, or also bast fibres, leather and preferably paper or paper pulp products, especially wood-containing paper.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: August 13, 1996
    Assignee: Sandoz Ltd.
    Inventor: Helmut A. Moser
  • Process for treatment of waste stream using Scytinostroma galactinum fungus ATCC 20966
    Patent number: 5545544
    Abstract: The white rot fungus Scytinostroma galactinum strain F361 and mutants thereof are particularly effective in selectively grading the lignin component of lignin-containing materials, particularly processed wood pulps including chemical pulps, and also particularly effective in degrading lignin degradation products such as chlorinated degraded lignin by-products as found, for example, in E-1 effluents, and also in degrading chlorine-containing aromatic compounds generally as found in aqueous waste streams containing the same.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 13, 1996
    Assignees: Sandoz Ltd., The Regents of the Univ. of Minnesota
    Inventors: Robert A. Blanchette, Theresa S. Brush, Roberta L. Farrell, Keith A. Krisa, Chittra Mishra
  • Compositions comprising paraesthetic agrochemicals
    Patent number: 5545663
    Abstract: Agricultural compositions comprising paraesthetic agrochemicals, such as pyrethroids, and an amount of urea effective to reduce the paraesthetic effect of such agrochemicals.
    Type: Grant
    Filed: December 6, 1994
    Date of Patent: August 13, 1996
    Assignee: Sandoz Ltd.
    Inventor: Sarangdhar S. Nakat
  • Herbicidal compositions comprising metolachlor and triketone herbicides
    Patent number: 5545607
    Abstract: Co-application of the chloroacetamide herbicide metolachlor with certain triketone herbicides provides improved herbicidal activity.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: August 13, 1996
    Assignee: Sandoz Ltd.
    Inventors: Theo Quaghebeur, Walter Van Loocke
  • Thiophen compounds and their preparation
    Patent number: 5543531
    Abstract: Processes for the preparation of N-(2,4-dimethylthien-3-yl)-N-(1-methoxyprop-2-yl)-chloroacetamide and of intermediates thereof, and novel intermediates useful for the preparation of N-(2,4-dimethylthien-3-yl)-N-(1-methoxyprop-2-yl)-chloroacetamide.
    Type: Grant
    Filed: April 8, 1992
    Date of Patent: August 6, 1996
    Assignee: Sandoz Ltd.
    Inventor: Peter F unfschilling
  • Use of certain 3,7-disubstituted indole compounds for treating depression or cognitive disorders
    Patent number: 5543426
    Abstract: 3,7-disubstituted indole derivatives of formula I ##STR1## wherein R.sub.1, R.sub.2, n, X, Y and Z are as defined in the description, are useful for the treatment of psychiatric disorders.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: August 6, 1996
    Assignee: Sandoz Ltd.
    Inventors: Arnold K. Dixon, Rudolf K. A. Giger
  • Calcitonin derivatives
    Patent number: 5541159
    Abstract: Peptide derivatives selected from (i) a calcitonin peptide and a LHRH antagonist peptide modified by at least one sugar residue and/or at least one short polyhydroxy compound or derivative, and (ii) a calcitonin peptide modified by at least one formyl and/or at least C.sub.3-5 alkyl attached to an amino group other than a N-terminal amino group, and (iii) a calcitonin peptide modified by a combination of said substituents, with the provisos thati) when the calcitonin peptide comprises at least one sugar residue a), this sugar residue is attached by a coupling other than a direct N-glycosidic bond to an .omega.-amino group of an .omega.-amino substituted side chain in the 24 position, andii) when the LHRH antagonist comprises at least one sugar residue a), this sugar residue is an Amadori sugar residue attached by a coupling other than a direct N-glycosidic bond to an .omega.-amino group of an .omega.
    Type: Grant
    Filed: November 29, 1994
    Date of Patent: July 30, 1996
    Assignee: Sandoz Ltd.
    Inventors: Rainer Albert, Wilfried Bauer, Fran.cedilla.ois Cardinaux, Janos Pless
  • Process for pretreating a textile material
    Patent number: 5538648
    Abstract: A process for improving the removal of undesired substances from a cellulosic textile material comprisingi) treating the textile material with an aqueous solution comprisinga) citric acid,b) an alkali metal or ammonium salt of a gluconic acid, andc) optionally a mineral acid (preferably in a minor amount).
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 23, 1996
    Assignee: Sandoz Ltd.
    Inventors: Dominik B ucheler, Saverio Fornelli
  • Sustained release formulations of water soluble peptides
    Patent number: 5538739
    Abstract: The invention discloses microparticles comprising a polypeptide, preferably somatostatin or an analog or derivative thereof, more preferably octreotide, in a polymeric matrix, preferably poly(lactide-co-glycolide) glucose. The invention also discloses sustained release formulations containing said microparticles and the use of said formulations in treating acromegaly and breast cancer.
    Type: Grant
    Filed: January 18, 1991
    Date of Patent: July 23, 1996
    Assignee: Sandoz Ltd.
    Inventors: David Bodmer, Jones W. Fong, Thomas Kissel, Hawkins V. Maulding, Jr., Oskar Nagele, Jane E. Pearson
  • Benzoquinoxalines, pharmaceutical compositions containing them and their use in treating schizophrenia
    Patent number: 5538971
    Abstract: 6-hydroxy or 6-alkoxy-1,2,3,4,4a,5,10,10a-octahydro-benzo[g]quinoxalines bearing in position 4 an optionally substituted phenyl group may be used in the treatment of schizophrenia, drug abuse or self-injurious behavior.
    Type: Grant
    Filed: May 27, 1994
    Date of Patent: July 23, 1996
    Assignee: Sandoz Ltd.
    Inventors: Peter Gull, Rudolf Markstein, Robert Swoboda
  • 2,4-diamino-3-hydroxycarboxylic acid derivatives
    Patent number: 5538997
    Abstract: The invention relates to compounds of formula I ##STR1## wherein the substituents have various significances. They can be prepared by conventional methods, e.g. coupling, substitution, deprotection or protection reactions.They possess interesting pharmacological properties and are thus indicated for use in the treatment of retroviral infections, particularly as HIV proteinase inhibitors.
    Type: Grant
    Filed: January 3, 1994
    Date of Patent: July 23, 1996
    Assignee: Sandoz Ltd.
    Inventors: Andreas Billich, Brigitte Charpiot, Peter Ettmayer, Hubert Gstach, Philipp Lehr, Dieter Scholz
  • Melanin compositions and uses thereof and resulting products
    Patent number: 5538752
    Abstract: Compositions comprising melanin or melanin precursors are useful for preventing or controlling decay of substrates such as cellulosic and other porous organic substrates. The compositions provide useful wood preservatives, wound dressings, and the like. In one embodiment, the compositions comprise melanin complexed with metal ions, particularly copper. The compositions may be applied as penetrating or surface treatments. Certain melanins are also particularly useful for removing metal ions from liquids.
    Type: Grant
    Filed: February 13, 1995
    Date of Patent: July 23, 1996
    Assignees: Regents of the Univ. of Minnesota, Sandoz Ltd.
    Inventors: Robert A. Blanchette, Theresa S. Brush, Roberta L. Farrell
  • Herbicidal substituted benzoyl bicycloalkanediones
    Patent number: 5536703
    Abstract: The invention relates to novel thioether derivatives of substituted benzoyl bicycloalkane diones, their use as herbicides and agricultural compositions comprising the same.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: July 16, 1996
    Assignee: Sandoz Ltd.
    Inventor: Shy-Fuh Lee
  • Cementitious compositions containing fly ash
    Patent number: 5536310
    Abstract: A cementitious composition comprising(A) 10-30 parts cementitious material;(B) 50-80 parts fly ash weight; and(C) 1.5-8 parts hydroxycarboxylic acid and/or salt thereof.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: July 16, 1996
    Assignee: Sandoz Ltd.
    Inventors: John W. Brook, David F. Factor, Frederick D. Kinney, Celeste L. McCallen, Andrea M. Young
  • Amine curable compositions
    Patent number: 5536775
    Abstract: Amine curable compositions containing a partially acrylated epoxy resin useful for forming protective and/or decorative coatings on a variety of substrates, particularly flooring substrates.
    Type: Grant
    Filed: November 4, 1994
    Date of Patent: July 16, 1996
    Assignee: Sandoz Ltd.
    Inventors: Benedict S. Curatolo, Frank V. Apicella, Jr., Thomas W. Richardson, Sr.
  • 2'-O, N.sup.6 -disubstituted and 2'-O, N.sup.6, 2-trisubstituted adenosines and their medicinal uses
    Patent number: 5534503
    Abstract: Adenosines derivatives of the formula ##STR1## wherein R.sub.1 is allyl, methallyl, straight or branched chain (C.sub.3-7)alkynyl, (C.sub.3-8)cycloalkyl, or phenyl mono- or independently of one another di-substituted by halogen having an atomic number of from 9 to 35, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, or CF.sub.3 ; R.sub.2 is hydrogen or C(.sub.1-4)alkyl, and R.sub.3 is (C.sub.1-4)alkyl, are useful for protecting vascular endothelium, for lowering blood lipid levels, and for treating raised blood pressure.
    Type: Grant
    Filed: October 27, 1994
    Date of Patent: July 9, 1996
    Assignee: Sandoz Ltd.
    Inventor: Fulvio Gadient