Patents Assigned to Sciences
  • Publication number: 20200067247
    Abstract: The present disclosure relates to a conductive slip ring for logging while drilling (LWD) instrument. The present disclosure utilizes a mechanical conductive slip ring to solve the problems of transmission of electric power and signals between two structures that have relative rotation, and the conductive slip ring has a simple structure, doesn't involve any complex circuit, and has low cost and high reliability. With the conductive slip ring in the present disclosure, there is no power transmission efficiency problem or signal transmission error rate problem. The conductive slip ring has high temperature-resistant, pressure-proof, and vibration-roof abilities, and can be applied widely.
    Type: Application
    Filed: August 29, 2019
    Publication date: February 27, 2020
    Applicant: Institute of Geology And Geophysics, Chinese Academy Of Sciences
    Inventors: Xinzhen He, Qingyun Di, Wenxuan Chen, Jiansheng Du, Qingbo Liu
  • Publication number: 20200063109
    Abstract: A phage composition and use thereof in inactivating antibiotic resistance pathogenic bacteria are disclosed. The phage composition includes three phages, and the phages all have been deposited at the China Center for Type Culture Collection on Aug. 1, 2018. The phages are a phage ?YSZKA under Accession No. CCTCC M 2018513, a phage ?YSZKP under Accession No. CCTCC M 2018514, and a phage ?YSZPA under Accession No. CCTCC M 2018515, respectively. The present invention provides a remediation method by applying a specific bacteriophage stock solution into a contaminated soil-plant system to directionally infect and inactivate a combined contamination of resistance pathogenic bacteria in the system and synergistically remove antibiotic resistance genes. In addition, the functional diversity and stability of a soil ecological environment are significantly restored, after the remediation.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 27, 2020
    Applicant: Institute of Social Science, Chinese Academy of Sciences
    Inventors: Mao YE, Yuanchao ZHAO, Mingming SUN, Zhongyun ZHANG, Dan HUANG, Xin JIANG
  • Publication number: 20200065330
    Abstract: An XML data manipulation method and apparatus, belonging to the field of data processing. The method comprises: obtaining a structured query language (SQL) manipulation instruction for extensible markup language (XML) data, and checking the SQL manipulation instruction (101); if checking is successful, recognizing the SQL manipulation instruction, and recognizing conditions included in the SQL manipulation instruction (102); transforming a keyword in the SQL manipulation instruction into an XML statement, and transforming the conditions included in the SQL manipulation instruction into XML conditions (103); and manipulating the XML data according to the XML statement and the XML conditions, and returning a manipulation result (104).
    Type: Application
    Filed: September 21, 2017
    Publication date: February 27, 2020
    Applicant: Kmerit (Suzhou) Information Science & Technology Co., Ltd.
    Inventor: Jinyun Zhang
  • Publication number: 20200066714
    Abstract: A BIPOLAR-CMOS-DMOS (BCD) semiconductor device and manufacturing method, which can integrate a Junction Field-Effect Transistor (JFET), two classes of Vertical Double-diffusion Metal Oxide Semiconductor (VDMOS), a Lateral Insulated-Gate Bipolar Transistor (LIGBT) and seven kinds of Laterally Diffused Metal Oxide Semiconductor (LDMOS), a low-voltage Negative channel Metal Oxide Semiconductor (NMOS), a low-voltage Positive channel Metal Oxide Semiconductor (PMOS), a low-voltage Negative-Positive-Negative (NPN) transistor and a low-voltage Positive-Negative-Positive (PNP) transistor, and a diode in the same chip. Bipolar devices in the analog circuit, power components in the switch circuit, Complementary Metal Oxide Semiconductor (CMOS) devices in the logic circuit and other kinds of lateral and vertical components are integrated. This present invention saves costs at the same time greatly improve chip integration.
    Type: Application
    Filed: January 24, 2019
    Publication date: February 27, 2020
    Applicant: University of Electronic Science and Technology of China
    Inventors: Ming QIAO, Song PU, Bo ZHANG
  • Publication number: 20200060988
    Abstract: The present invention discloses an application of clofoctol for manufacturing a pharmaceutical product for treating human neuroglioma. The clofoctol is a pharmaceutical product for treating an upper respiratory tract infection. The clofoctol exerts a significant and specific inhibition of a glioma stem cell activity relative to a human neuroglioma cell or a normal human astroglia, human embryonic kidney cell, and human neural stem cell. A glioma stem cell treated with the clofoctol exhibited significantly reduced self-renewal, tumorsphere formation, and in vivo tumor formation in a nude rat. In vivo experiments using a zebrafish glioma transplantation model and a nude rat glioma transplantation model provided in vivo verification for the therapeutic efficacy of the pharmaceutical product against glioma.
    Type: Application
    Filed: March 20, 2017
    Publication date: February 27, 2020
    Applicant: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
    Inventors: Xiaozhong PENG, Yan HU, Wei HAN, Boqin QIANG
  • Publication number: 20200060102
    Abstract: A gas permeable flowerpot (100), comprising: a tray (10), a flowerpot body (30), and a bottom plate (50). The tray (10) comprises an accommodating trough (10A) for accumulating water; the flowerpot body (30) is filled with soil; the flowerpot body (30) is provided with a plurality of stacked hollow subunits (32); the soil in each hollow subunit (32) is gas permeable; the bottom plate (50) is made of a micro-porous water absorbing material and comprises a water permeable plate (51) and a water absorbing column (52) which extends downwardly out from the water permeable plate (51); the soil is in contact with the water permeable plate (51), and the water absorbing column (52) extends into the accommodating trough (10A). Because of the water permeability of the water permeable plate (51), excessive water can flow through the water permeable plate (51) into the tray (10) to prevent roots from being eroded by water.
    Type: Application
    Filed: March 25, 2016
    Publication date: February 27, 2020
    Applicant: Renchsand Eco-Environment Protection Science and Technology Co., Ltd.
    Inventor: Shengyi Qin
  • Publication number: 20200062686
    Abstract: Provided is a method for preparing a lower unsaturated fatty acid ester, which comprises carrying out an aldol condensation reaction between dimethoxymethane (DMM) and a lower acid or ester with a molecular formula of R1—CH2—COO—R2 on an acidic molecular sieve catalyst in an inert atmosphere to obtain a lower unsaturated fatty acid or ester(CH2?C(R1)—COO—R2), wherein R1 and R2 are groups each independently selected from the group consisting of H- and C1-C4 saturated alkyl group.
    Type: Application
    Filed: November 25, 2016
    Publication date: February 27, 2020
    Applicant: Dalian Institute of Chemical Physics, Chinese Academy of Sciences
    Inventors: Zhanling MA, Wenliang ZHU, Xiangang MA, Hongchao LIU, Yong LIU, Youming NI, Shiping LIU, Qiwei CHEN, Zhongmin LIU
  • Publication number: 20200067272
    Abstract: A micro disk laser having a greater strength of oscillation in one direction than in another direction and unidirectionally oscillating includes a micro disk having an oval shape corresponding to a modified ellipse obtained by changing a length of a short axis of an ellipse according to a position of a long axis while lengths of first and second side portions of the long axis are fixed in the ellipse, the ellipse having the long axis and the short axis having a different length than the long axis.
    Type: Application
    Filed: October 12, 2017
    Publication date: February 27, 2020
    Applicant: Daegu Gyeongbuk Institute of Science and Technology
    Inventor: Chil Min KIM
  • Publication number: 20200061684
    Abstract: A phage and use thereof in soil remediation are disclosed. The phage ?YSZPK has been deposited at the China Center for Type Culture Collection on Aug. 1, 2018 under Accession No. CCTCC M 2018516, and its taxonomic designation is Pseudomonas aeruginosa and Klebsiella phage ?YSZPK. Biochar and the screened phage are combined and returned into contaminated soil to synergistically control and deeply track and inactivate transmission and spread of antibiotic resistance pathogenic bacteria and resistance genes in a soil-vegetable system. The combination of the biochar and the phage ?YSZPK not only clearly improves the functional stability of microbial community in the soil-vegetable system, but also significantly alleviates the dissemination of the antibiotic resistance pathogenic bacteria in the soil-vegetable system to prevent secondary pollution, thereby providing a new solution for biological remediation and control of farmland soil contaminated by antibiotic resistance pathogenic bacteria in China.
    Type: Application
    Filed: August 21, 2019
    Publication date: February 27, 2020
    Applicant: Institute of Soil Science, Chinese Academy of Sciences
    Inventors: Mao YE, Yuanchao ZHAO, Mingming SUN, Zhongyun ZHANG, Dan HUANG, Yongrong BIAN, Feng HU, Xin JIANG
  • Publication number: 20200061052
    Abstract: The present invention relates to a pharmaceutical dosage form for transmucosal delivery of an active agent to two or more mucosal surfaces. The dosage form is presented as a transmucosal delivery device. The devices of the invention may include at least two mucoadhesive surfaces. The devices may further include an intermediate layer disposed between the mucoadhesive layers. The pharmaceutical can be incorporated in any one or all of the mucoadhesive layers or the intermediate layer. Upon application, the device adheres to at least two surfaces, providing transmucosal delivery of the drug to at least two surfaces.
    Type: Application
    Filed: September 5, 2019
    Publication date: February 27, 2020
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Niraj Vasisht, Andrew Finn
  • Patent number: 10572832
    Abstract: Systems and methods include: collecting digital threat scores of an incumbent digital threat machine learning model; identifying incumbent and successor digital threat score distributions; identifying quantiles data of the incumbent digital threat score distribution; collecting digital threat scores of a successor digital threat machine learning model; calibrating the digital threat scores of the successor digital threat score distribution based on the quantiles data of the incumbent digital threat score distribution and the incumbent digital threat score distribution; and in response to remapping the digital threat scores of the successor digital threat score distribution, publishing the successor digital scores in lieu of the incumbent digital threat scores based on requests for digital threat scores.
    Type: Grant
    Filed: May 14, 2019
    Date of Patent: February 25, 2020
    Assignee: Sift Science, Inc.
    Inventors: Fred Sadaghiani, Aaron Beppu, Jacob Burnim, Alex Paino
  • Patent number: 10570176
    Abstract: The present invention relates to the field of polypeptide medicine, and relates to polypeptides against hepatitis B virus X Protein and uses thereof. Specifically, the present invention relates to polypeptides comprising D-amino acids, which have a function of inhibiting hepatitis B virus X protein, and inhibit HBx activities, inhibit replication of hepatitis B virus DNA and expression of related antigens (e.g., HBeAg) at molecular level, cellular level and animal level, and further inhibit hepatitis and hepatic cirrhosis caused by hepatitis B virus infection and liver cancer that occurs on the basis of hepatic cirrhosis. The polypeptides can be widely used in the prevention and treatment of liver diseases after hepatitis B infection, including hepatitis, hepatic cirrhosis, and liver cancer.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: February 25, 2020
    Assignee: Tianjin TOPTECH Bio-Science & Technology Co., Ltd.
    Inventors: Xiaodong Zhang, Lihong Ye
  • Patent number: 10570385
    Abstract: A non-enzymatic method is provided for binding a first nucleic acid chain to a second nucleic acid chain without introducing a sulfur atom into the combined nucleic acid chain, the method comprising reacting a first nucleic acid chain having a phosphorothioate group at the 3? or 5? terminus with a second nucleic acid chain having a hydroxyl group or an amino group at the 3? or 5? terminus in the presence of an electrophile that has a leaving group and is configured to leave the leaving group and bind to a sulfur atom of the phosphorothioate group of the first nucleic acid chain at the site to which the leaving group had been bound, and remove the sulfur atom from the phosphorothioate group of the first nucleic acid chain and a hydrogen atom from the hydroxyl group or from the amino group of the second nucleic acid chain via a nucleophilic substitution with an oxygen atom of the hydroxyl group or a nitrogen atom of the amino group of the second nucleic acid chain, and thereby form a bond between a phosphorus a
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: February 25, 2020
    Assignee: Japan Science and Technology Agency
    Inventors: Hiroshi Abe, Hideto Maruyama
  • Patent number: 10568320
    Abstract: The present invention provides novel compositions and methods for using the insect neuromodulator tyramine and/or one or more derivatives thereof delivered to insect populations to control certain aspects of such populations. The amount of tyramine and/or one or more derivatives thereof delivered on a per insect basis is significantly greater than a naturally-occurring amount of tyramine normally found in insects and causes deleterious effects including mortality of certain insect life forms and disruption of the reproductive capacity of others in the population.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: February 25, 2020
    Assignees: The United States of America, as represented by the Secretary of Agriculture, Foresight Science & Technology Inc.
    Inventors: Robert K. Vander Meer, Satya P. Chinta
  • Patent number: 10570049
    Abstract: The invention provides a glazed composite manufactured using waste materials, wherein the waste materials are capable of producing ceramic forming oxides, glass modifying oxides and ceramic modifying oxides. The waste materials include ceramic waste and colored glass waste. The invention also provides a method for manufacturing composition of the glazed composite.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: February 25, 2020
    Assignee: King Abdul Aziz City for Science and Technology (KACST)
    Inventors: Mohammed A Binhussain, Esmat M A Hamzawy, Omar A Alharbi
  • Patent number: 10573658
    Abstract: A method of manufacturing three-dimensional semiconductor device includes the steps of: forming a stack structure of a plurality of a first material layers and a second material layers on a substrate in the memory cell region; etching the stack structure to form a plurality of trenches; forming channel layers in the plurality of trenches; and reducing the surface roughness and the interface state by performing annealing treatment to at least one surface of the channel layers.
    Type: Grant
    Filed: July 10, 2014
    Date of Patent: February 25, 2020
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventor: Zongliang Huo
  • Patent number: 10571426
    Abstract: A pixel circuit acts as a sensing element in a sensing device. The pixel circuit includes a sensing electrode, a first gate electrically connected to the sensing electrode, a second gate in electrical communication with the first gate, and a readout device that is electrically connected to the second gate. An input voltage applied to the sensing electrode is amplified between the first gate and the second gate, the amplification being measured as an output signal from the readout device to perform a sensing operation. For example, the output signal may be relatable to pH, analyte measurements, or other properties of sample liquids analyzed by the sensing device. A sensing device may include multiple pixels disposed on a substrate, each pixel including said pixel circuit. Driver circuits controlled by control electronics are configured to generate signals that selectively address the pixels and to read out voltages at the sensing electrodes.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: February 25, 2020
    Assignee: Sharp Life Science (EU) Limited
    Inventors: Benjamin James Hadwen, Campbell Donald Brown, Christopher James Brown, Gregory Gay, Sally Anderson
  • Patent number: 10569224
    Abstract: A device which includes a pulse dampener and a degasser or de-bubbler. The device includes a fluid flow path and a fluid chamber located within the device. In addition, the device includes a pulse dampening membrane for dampening pulses in the fluid as it flows through the device. The device also includes a degassing membrane for degassing the fluid as it flows through the device, and/or a de-bubbling membrane for removing gas bubbles from the fluid as it flows through the device. The degassing or de-bubbling membrane can be separate and distinct from the dampening membrane. The de-bubbling membrane can be in addition to or in place of the degassing membrane in some embodiments.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: February 25, 2020
    Assignee: IDEX Health & Science LLC
    Inventors: Daniel M. Hartmann, Carl Sims, David Steckman, Leanne Elson
  • Patent number: 10571033
    Abstract: Disclosed is a rotary valve 1 comprising a stator 20 and a rotor 40 generally in rotary sliding engagement with the said stator about a valve axis RA, the stator including a plurality of fluid ports 22, 26, 28, the rotor 40 being operable to selectively fluidically interconnect two or more of said ports during its rotary sliding engagement. The valve further includes an actuator (70) for disengagement of the rotor from the stator to enable efficient cleaning of the valve interconnections.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: February 25, 2020
    Assignee: GE Healthcare Bio-Sciences AB
    Inventor: Bjorn Olovsson
  • Patent number: 10571441
    Abstract: The invention discloses a piston for a process column, said piston comprising a top side and a bed contact side, wherein said top side comprises a drainage trench.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: February 25, 2020
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Andreas Bergstrom, Stefan Kjell Eriksson