Abstract: Methods, computer program products, and systems are described that include accepting at least one attribute of at least one individual, querying at least one database at least partly based on the at least one attribute, selecting from the at least one database at least one prescription medication and at least one artificial sensory experience to address the at least one attribute of at least one individual, and/or presenting an indication of the at least one prescription medication and the at least one artificial sensory experience at least partly based on the selecting from the at least one database at least one prescription medication and at least one artificial sensory experience to address the at least one attribute of at least one individual.
Type:
Grant
Filed:
September 14, 2016
Date of Patent:
February 25, 2020
Assignee:
The Invention Science Fund I, LLC
Inventors:
Roderick A. Hyde, Muriel Y. Ishikawa, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, Elizabeth A. Sweeney, Lowell L. Wood, Victoria Y. H. Wood
Abstract: Superhydrophilic and antifogging non-porous TiO2 films for glass substrates and methods of providing the TiO2 films are provided. The TiO2 films may maintain a water contact angle less than 5° in the dark for five days after an annealing treatment, and the water contact angle of the TiO2 films may stabilize at less than 20° after ten days from the annealing treatment. The TiO2 films may have a thickness of about 20 nm and may be transparent. The methods may include depositing a TiO2 film on a glass substrate using e-beam evaporation. The methods may further include annealing the TiO2 film after depositing the TiO2 film on the glass substrate. The methods may not include UV radiation.
Type:
Grant
Filed:
August 30, 2017
Date of Patent:
February 25, 2020
Assignee:
Khalifa University of Science and Technology
Abstract: Methods, systems, computer programs, circuits and workstations are configured to generate at least one two-dimensional weighted CBF territory map of color-coded source artery locations using an automated vascular segmentation process to identify source locations using mutual connectivity in both image and label space.
Abstract: The present application discloses a communication processing method and apparatus. A specific implementation of the method includes: receiving, through a tunnel bridge to a first physical machine, a packet sent from a virtual machine, the first physical machine being a host machine of the virtual machine; determining whether the packet is an Address Resolution Protocol (ARP) request packet, and obtaining a destination address of the packet; if the packet is the ARP request packet and a destination address of the packet is not an address of a virtual machine in the first physical machine, writing a predetermined pseudo physical address into an ARP response and returning the ARP response; and if the packet is not the ARP request packet, sending the packet to a terminal associated with the destination address of the packet. This implementation reduces load of network nodes.
Type:
Grant
Filed:
December 3, 2015
Date of Patent:
February 25, 2020
Assignee:
Beijing Baidu Netcom Science and Technology Co., Ltd.
Abstract: A composite collagen hydrogel material for use in tissue engineering, and an implantable ophthalmic device comprising such composite material. The composite material comprises: a first collagen network comprising collagen crosslinked with a first crosslinking agent, and/or a second collagen network comprising collagen crosslinked with a second crosslinking agent, and a three dimensional collagen mesh comprising partially and plastically compressed collagen hydrogel with a compression degree of 50-95%, wherein the three dimensional collagen mesh is embedded in the first collagen network and/or second collagen network, and the first collagen network and/or the second collagen network and the three dimensional collagen mesh are physically and chemically interconnected in the composite collagen hydrogel material.
Abstract: The present application discloses a method and apparatus for elastically scaling a virtual machine cluster. A specific implementation of the method includes: calculating a first amount of residual resources of virtual machines in a virtual machine cluster during service deployment; acquiring an amount of resources demanded by a service to be deployed; acquiring a configuration level of the virtual machines in the virtual machine cluster; determining a virtual machine having a predetermined configuration level as a target virtual machine based on whether the first amount of residual resources satisfies the amount of resources demanded; and deploying the service to be deployed to the target virtual machine.
Type:
Grant
Filed:
February 10, 2017
Date of Patent:
February 25, 2020
Assignee:
Beijing Baidu Netcom Science and Technology Co., Ltd.
Abstract: Disclosed are applications of a mussel adhesive protein or preparations thereof in suppression of skin inflammations. Specifically disclosed are applications of a mussel adhesive protein, preparations thereof and applications thereof in dermatitis, eczema, skin ulcer, technologies related to burns (comprising skin grafting), perniones, surgical incisions, herpes, abrasions, scars, psoriasis, erythema multiforme, skin damage after radiotherapy, skin cancers, folliculitis, urticaria and drug eruption, and applications in sunburn, polymorphous light eruption, pathological alopecia (comprising hair transplant), acne vulgaris, rosacea (that is, acne rosacea), and the like, and applications in the treatment of otitis externa.
Type:
Grant
Filed:
July 20, 2015
Date of Patent:
February 25, 2020
Assignee:
Jiangyin Bengt I. Samuelsson Institute of Life Science Co., Ltd.
Abstract: The present disclosure provides methods and systems for improved detection and/or quantification of selenium (Se) and/or silicon (Si) in samples. In certain embodiment, the methods and systems feature the use of carbon dioxide (CO2) as a reaction gas in a reaction cell chamber, such as a dynamic reaction cell (DRC), of an inductively coupled plasma mass spectrometer (ICP-MS). It is found that the use of CO2 as a reaction gas effectively eliminates (or substantially reduces) interfering ionic species for the analytes Se and Si, particularly in samples with complex matrices, and/or in samples with low levels of analyte, thereby enabling more accurate detection of analyte at lower detection limits and in samples having complex matrices.
Abstract: Disclosed herein is a positive pressure relief valve having a valve assembly, a trigger mechanism, an inlet manual override knob, and an outlet manual override knob. The valve assembly may comprises a valve throat and a main piston positioned at least partially within the valve throat, the main piston configured to selectively open and close the valve throat as a function of a pressure at the inlet to the valve assembly. The valve assembly may comprise a set of throat inserts within the valve throat. The trigger mechanism serves to quickly pressurize the main piston's diaphragm. The trigger mechanism may be positioned in a trigger mechanism housing at the outlet end of the valve assembly. The inlet and outlet manual override knob may be coupled to the main piston and configured to pull or push the main piston, thereby displacing the main piston to open the valve assembly.
Type:
Grant
Filed:
April 6, 2018
Date of Patent:
February 25, 2020
Assignee:
Aurora Flight Sciences Corporation
Inventors:
Christopher Krebs, David Kordonowy, Robert Renshaw
Abstract: The present invention relates to the field of the production of transgenic plants through Agrobacterium-mediated transformation of cells of somatic embryogenic calli or embryogenic suspension cultures and regeneration of the transformed cells into fruit-setting plants. In particular, the present invention relates to the production of transgenic plants in the Euphorbiaceae family. The present invention further relates to media compositions, selection methods and engineered Agrobacterium tumefaciens strains that improve Agrobacterium-mediated transformation efficiency.
Type:
Grant
Filed:
November 14, 2018
Date of Patent:
February 25, 2020
Assignee:
Temasek Life Sciences Laboratory Limited
Inventors:
Lin Cai, Longhua Sun, Lin Fu, Lianghui Ji
Abstract: The development and manufacture of thermal interface materials including, among other forms, greases, pastes, gels, adhesives, pads, sheets, solders and phase change materials, with good through-plane thermal conductivity for thermal interface applications. The good through-plane thermal conductivity is achieved through the formation of a conductive network by the use of thermal conductive material-coated fillers, combinations of thermal conductive material-coated fillers and uncoated fillers.
Type:
Grant
Filed:
October 5, 2016
Date of Patent:
February 25, 2020
Assignee:
XG Sciences, Inc.
Inventors:
Hiroyuki Fukushima, Thomas Ritch, Jessica Russell, Liya Wang
Abstract: An example device includes a silicon substrate having a first substrate surface and a second substrate surface; a plurality of layers associated with one or more electronic components of an integrated circuit (IC), where the plurality of layers are deposited on the second substrate surface; a lithium-based battery having a plurality of battery layers deposited on the first substrate surface of the silicon substrate, where the lithium-based battery includes an anode current collector and a cathode current collector; a first through-silicon via (TSV) passing through the silicon substrate and providing an electrical connection between the anode current collector and the plurality of layers associated with the one or more electronic components of the IC; and a second TSV passing through the silicon substrate and providing an electrical connection between the cathode current collector and the plurality of layers associated with the one or more electronic components of the IC.
Type:
Grant
Filed:
October 8, 2018
Date of Patent:
February 25, 2020
Assignee:
Verily Life Sciences LLC
Inventors:
William James Biederman, Daniel James Yeager, Brian Otis
Abstract: The present invention relates to compounds of general formula (I). wherein A represents an optionally substituted heterocycle group, B represents an aryl or heteroaryl group and wherein X, R1, R2, R3, R4 and R5 are as defined in the description. Compounds of formula (I) are useful to destroy, inhibit, or prevent the growth or spread of cells, especially malignant cells, into surrounding tissues implicated in a variety of human and animal diseases.
Abstract: A timbre-selectable human voice playback system and a timbre-selectable human voice playback method thereof are provided. The timbre-selectable human voice playback system includes a speaker, a storage and a processing apparatus. The storage saves a text database. The processing apparatus is connected to the speaker and the storage. The processing apparatus obtains real human voice signals, converts the text of the text database into original synthetic human voice signals with the text-to-speech technology, and transforms the original synthetic voice signals into timbre-specific human voice signals with a timbre transformation model. The timbre-transformation model is trained with the real human voice signals collected from a specific person. Then, the processing apparatus plays the transformed human voice signals with the speaker. Accordingly, a user can listen to his favorite voice timbre and the transformed voice signal carrying selected content anytime and anywhere.
Type:
Application
Filed:
April 8, 2019
Publication date:
February 20, 2020
Applicant:
National Taiwan University of Science and Technology
Abstract: We describe the use of exosome such as mesenchymal stem cell exosomes in a method of promoting, restoring or enhancing homeostasis in an individual suffering from graft versus host disease (GVHD) or epidermolysis bullosa (EB). The homeostasis may comprise immune homeostasis such as maintenance of an immune response. The method may comprise administering a therapeutically effective amount of exosome to the individual.
Type:
Application
Filed:
October 23, 2019
Publication date:
February 20, 2020
Applicant:
Agency for Science, Technology and Research (A*STAR)
Abstract: An optoelectronic semiconductor structure includes a first n-type semiconductor layer, a first quantum well layer, a first p-type semiconductor layer, and a second n-type semiconductor layer. The first quantum well layer is disposed on the first n-type semiconductor layer. The first p-type semiconductor layer is disposed on the first quantum well layer. The second n-type semiconductor layer is disposed on the first p-type semiconductor layer. The second n-type semiconductor layer includes both an n-type dopant and a p-type dopant. The concentration of the n-type dopant in the second n-type semiconductor layer is greater than the concentration of the p-type dopant in the second n-type semiconductor layer. The first n-type semiconductor layer, the first quantum well layer, the first p-type semiconductor layer, and the second n-type semiconductor layer form a bipolar phototransistor structure. A manufacturing method of the optoelectronic semiconductor structure is also provided.
Type:
Application
Filed:
August 15, 2019
Publication date:
February 20, 2020
Applicant:
National Taiwan University of Science and Technology
Abstract: Disclosed are systems and methods for characterizing corneal shape abnormalities. These methods may be used to differentiate corneas having subclinical keratoconus from other conditions which cause distortion of corneal shape, including warpage of the cornea due to contact lens wear. Also disclosed is classification scheme to aid diagnosis of corneal conditions and thereby guide clinical decision making regarding patient treatment. This classification scheme is based on computed properties of corneal shape, is amenable to automation, and may be implemented in an integrated system or provided in the form of software encoded on a computer-readable medium.
Abstract: Methods of treating acute myeloid leukemia, chronic lymphocytic leukemia and myeloproliferative neoplasms that involve the administration of combinations of small molecule compounds are disclosed.
Type:
Application
Filed:
October 31, 2017
Publication date:
February 20, 2020
Applicant:
Oregon Health & Science University
Inventors:
Jeffrey Tyner, Stephen Kurtz, Brian Druker, Elie Traer, Christopher Eide, Motomi Mori, Andrew Kaempf
Abstract: The present invention discloses a nicotinyl alcohol ether derivative, a preparation method therefor, and a pharmaceutical composition and uses thereof. Specifically, the invention relates to nicotinyl alcohol ether derivatives represented by formula (I), a pharmaceutically-acceptable salt thereof, a stereoisomer thereof, a preparation method therefor, a pharmaceutical composition containing the one or more compounds, and uses of the compounds in treating diseases related to PD-1/PD-L1 signal channels, such as cancers, infectious diseases and autoimmune diseases.
Type:
Application
Filed:
May 23, 2017
Publication date:
February 20, 2020
Applicants:
Institute of Materia Medica, Chinese Academy of Medical Sciences, Tianjin Chase Sun Pharmaceutical Co., LTD
Inventors:
Zhiqiang Feng, Xiaoguang Chen, Yang Yang, Yi Zheng, Fangfang Lai, Ming Ji, Chuan Zhou, Lijing Zhang, Ke Wang, Nina Xue, Ling Li
Abstract: A thermoacoustic imaging method comprises administering a thermoacoustic imaging contrast agent to a subject, the thermoacoustic imaging contrast agent having a viscosity higher than blood and substantially similar to a viscosity of a known computed tomography (CT) or magnetic resonance imaging (MRI) contrast agent; and imaging the subject with a thermoacoustic imaging system. The thermoacoustic imaging contrast agent may comprise an ionic solution and thickening agent mixture, with an optional heating agent. The ionic salt makes 0.5% to 5.0% of the ionic solution by weight and the remainder of the ionic solution is water. The thickening agent makes 3% to 50% of the mixture by weight.
Type:
Application
Filed:
August 17, 2018
Publication date:
February 20, 2020
Applicant:
ENDRA Life Sciences Inc.
Inventors:
Michael M. Thornton, Charlton Chen, Paul A. Picot, Marco A. Mena