Patents Assigned to SCIENTIFIQUE (CNRS)
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Patent number: 11002977Abstract: Device for shaping a laser beam for an atomic sensor, comprising a retroreflector prism with an entrance area, an exit area and two reflection surfaces forming a right angle therebetween. The device for shaping includes a linear polarizer disposed upstream from the entrance area of the retroreflector prism for linearly polarizing a laser beam entering into the retroreflector prism by the entrance area, and a form birefringence plate disposed downstream from the exit area of the retroreflector prism to circularly polarize a laser beam exiting from the retroreflector prism by the exit area.Type: GrantFiled: July 21, 2016Date of Patent: May 11, 2021Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRSInventors: Nicolas Passilly, Christophe Gorecki, Vincent Maurice
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Patent number: 11005150Abstract: Disclosed is an assembly for the propagation of waves of frequencies between 1 GHz and 10 THz, including: (a) a waveguide to guide the waves, the waveguide being produced from a plastic material, a part of the waves propagating inside this waveguide and another part of the waves propagating outside this waveguide; and (b) a protective covering which surrounds the waveguide delimiting one or more spaces between the waveguide and the covering, in which space or spaces the waves propagating outside the waveguide are contained, the protective covering thus forming a barrier to protect these waves from external disturbances.Type: GrantFiled: May 2, 2017Date of Patent: May 11, 2021Assignees: UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRSInventors: Florian Voineau, Anthony Ghiotto, Eric Kerherve
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Publication number: 20210128041Abstract: The present invention concerns an ergometer (10) comprising at least one training assembly, each assembly comprising: a training element (11), -at least one hydraulic cylinder (12) comprising a pressure chamber (32), said training element (11) being linked to said at least one hydraulic cylinder (12) such that a hydraulic pressure value applied in the pressure chamber (32) of said or at least one of said corresponding cylinders determines a force opposing the movement of said training element (11) by a user, and at least one control unit (13, 14) for supplying the pressure chamber (32) of said or one corresponding hydraulic cylinder (12) with pressurised hydraulic fluid such that said pressure chamber (32) has a chosen pressure value during at least a part of the muscle exercises carried out by the user, said control unit (13, 14) being linked to said pressure chamber (32) of the corresponding hydraulic cylinder (12) by a hydraulic fluid supply circuit.Type: ApplicationFiled: December 20, 2017Publication date: May 6, 2021Applicants: UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT POLYTECHNIQUE DE BORDEAUX, ECOLE NATIONALE SUPERIEURE DES ARTS ET METIERSInventors: Jocelyn SABATIER, Frédéric BOS, Adrien CAPORALE, Ludovic DELHOMME, Anne THÉVENOUX, Fanny MUNSCH
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Publication number: 20210131967Abstract: Optical device for optical fluorescence microscopy, comprising a spatial modulator (1), a microscope objective (2), a beamsplitter (3) and a camera (4), wherein the beamsplitter (3) is placed between the spatial modulator (1) and the microscope objective (2), wherein the beamsplitter (3) is placed between the camera (4) and the microscope objective (2), and wherein a prism (5) is placed between the beamsplitter (3) and the camera (4).Type: ApplicationFiled: December 14, 2018Publication date: May 6, 2021Applicants: ALVEOLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITÉ DE BORDEAUXInventors: Vincent Studer, Rémi Galland
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Publication number: 20210130385Abstract: The present invention relates to a compound of formula (I): (I) as defined in the description. The present invention also relates to a method for extracting biological membrane-associated membrane proteins, comprising a step of bringing an aqueous solution of biological membrane-associated membrane proteins into contact with at least one compound of the invention. The present invention also relates to a method for stabilizing membrane proteins in solution in an aqueous solution, comprising a step (i) consisting in bringing an aqueous solution of a membrane protein in solution into contact with at least one compound of the invention.Type: ApplicationFiled: December 27, 2017Publication date: May 6, 2021Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITE GRENOBLE ALPESInventors: Pierre FALSON, Julien DAUVERGNE, Ahcène BOUMENDJEL, Marine PEUCHMAUR, Kim Anh NGUYEN, Sandrine MAGNARD
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Publication number: 20210135329Abstract: A microwave component (10) of the type substrate integrated transmission line, comprises at least one upper layer (14) having at least one electrically conductive surface (26), a lower layer (16) having at least one electrically conductive surface (44), and a central layer (18) defining a propagation area (20) of an electromagnetic wave extending along a propagation axis. The upper layer (14) comprises at least an upper hole (30) passing through it; the lower layer (16) comprises at least one lower hole (46) passing through it. An electrically conductive wire (22) is received through the upper hole (30), the propagation area (20) and the lower hole (46), the conductive wire (22) being electrically connected to the electrically conductive surface (26) of the upper layer (14) and the electrically conductive surface (44) of the lower layer (16).Type: ApplicationFiled: June 1, 2018Publication date: May 6, 2021Applicants: UNIVERSITÉ DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE NATIONAL D'ETUDES SPATIALESInventors: Anthony GHIOTTO, Frédéric PARMENT
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Patent number: 10998457Abstract: Fabrication of a double-sided photovoltaic cell, with two opposite active surfaces, comprising a step of depositing, on each active surface, at least one electric contact. The deposition step comprises in particular a shared operation of depositing on each of the active surfaces, implemented by electrolysis in a shared electrolysis tank comprising: a first compartment for depositing a metal layer on a first active surface of the cell, for fabrication of a contact comprising said metal layer on the first active surface; and a second compartment for depositing, by oxidation, a metal oxide conductor layer on the second active surface of the cell, for the fabrication of a contact comprising said metal oxide layer on the second active surface.Type: GrantFiled: October 4, 2017Date of Patent: May 4, 2021Assignees: ELECTRICITE DE FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, PARIS SCIENCES ET LETTRES—QUARTIER LATINInventors: Pierre-Philippe Grand, Daniel Lincot
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Patent number: 10998549Abstract: The invention relates to a process for the preparation of sodium-based solid compounds, such as sodium-based solid alloys and sodium-based crystalline phases by ball-milling using metallic sodium as starting material. The invention also relates to some sodium-based crystalline P?2-phases and to Na-based vanadium phosphates phases (Na(3+y)V2(PO4)3) with 0<y?3 and Na-based vanadium fluorophosphates phases (Na(3+z)V2(PO4)2F3) with 0<z?3, in particular Na4V2(PO4)2F3, obtained by such a process and to their use, as active material for positive electrode, in a Na-ion battery.Type: GrantFiled: June 15, 2016Date of Patent: May 4, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE TOULOUSE III—PAUL SABATIER, SORBONNE UNIVERSITE, COLLEGE DE FRANCEInventors: Jean-Marie Tarascon, Patrick Rozier, Biao Zhang, Romain Dugas
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Patent number: 10995089Abstract: The present invention concerns a compound of formula (I): H or one of its pharmaceutically acceptable salts, especially for use as inhibitors of the ERK kinase activity in particular ERK2 activity, it also concerns prodrugs of these compounds.Type: GrantFiled: November 17, 2016Date of Patent: May 4, 2021Assignees: AGV DISCOVERY, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE MONTPELLIERInventors: Jean-François Guichou, Cédric Bories, Clément Geoffroy, Charline Duquenne, Muriel Gelin, Gilles Labesse, Yannick Bessin, Loic Mathieu
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Patent number: 10998691Abstract: A method and system for adjusting the profile of a laser wavefront formed by at least a laser beam to a desired laser wavefront profile, the laser beam or beams presenting random phases and intensities, comprises a mixing module, configured to generate, from interference phenomena among the laser beam or beams, a laser field, a second intensity measuring module configured to measure the mixed intensities of the laser field portions, a calculation unit configured to calculate one or several phase correction values of the phase of the laser beam or the phases of laser beams, from the intensities of the laser beams, the mixed intensities and one or several predetermined target phases, and a phase adjustment module configured to apply the phase correction value or values obtained from the calculation unit to the laser beam phases.Type: GrantFiled: January 17, 2019Date of Patent: May 4, 2021Assignees: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ DE LIMOGESInventors: Paul Armand, Jérémy Saucourt, Vincent Kermene, Agnès Desfarges-Berthelemot, Joël Benoist, Alain Barthelemy, Julien Leval
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Publication number: 20210122732Abstract: A compound of formula (Ie): wherein Y1 represents an aryl group, X2 represents a —O— group, a —NH— group, a —S— group, a —CO—NH— group, a —NH—CO—NH— group, a —NH—CO— group, a —CH(OH)— group, a —CH(COOH)NH— group, a —CH(COOCH3)NH— group, a —C(OH)(CH2OH)—, a group, a divalent 5-membered heteroaromatic ring comprising 1, 2, 3 or heteroatoms, a —SO2— group, or a —SO2—NH— group, Y2 represents a hydrogen atom, a hydroxyl group, a (C1-C4)alkoxy group, a —CHC(OH)2, a COORf, wherein Rf represents a hydrogen atom or a (C1-C4)alkyl group, a morpholinyl group, a dihydropyranyl group, a group, a group, a —PO(ORf)(OR?f) group, wherein Rf and R?f independently represents a hydrogen atom or a (C1-C4)alkyl group, an oxetanyl group, a —Si(CH3)3 group, a —NHCOO—(C1-C4)alkyl group, or a —CR1R2R3 group, or any of its pharmaceutically acceptable salt and pharmaceutical compositions containing them and to synthesis process for manufacturing them.Type: ApplicationFiled: July 9, 2019Publication date: April 29, 2021Applicants: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, INSTITUT CURIEInventors: Didier SCHERRER, Jamal TAZI, Florence MAHUTEAU-BETZER, Romain NAJMAN, Julien SANTO, Cécile APOLIT
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Publication number: 20210123916Abstract: The invention relates to a method for diagnosing a cancer in a mammal in a need thereof. The method comprises the following steps: collecting a biological sample from said mammal; determining, from said biological sample, if the ADAMTSL5 gene is overexpressed; diagnosing a cancer from the determination of the overexpression of said gene. It also relates to a kit for determining an overexpression of the ADAMTSL5 gene in a biological sample obtained from a mammal, to a pharmaceutical composition comprising an agent targeting ADAMTSL5 or the ADAMTSL5 pathway as well as a pharmaceutically acceptable carrier for use in the treatment of a cancer, and to a use of an ADAMTSL5 mRNA or protein as a biomarker of cancer.Type: ApplicationFiled: March 29, 2019Publication date: April 29, 2021Applicants: UNIVERSITE D'AIX-MARSEILLE (AMU), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Flavio Maina, Maria Arechederra, Rosanna Dono, Timothy Mead, Suneel Apte
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Patent number: 10992061Abstract: An elementary antenna includes a planar radiating device comprising a substantially plane radiating element and a transmit and/or receive circuit comprising at least one amplification chain of a first type and at least one amplification chain of a second type, each amplification chain of the first type being coupled to at least one excitation point of a first set of at least one excitation point of the radiating element and each amplification chain of the second type being coupled to at least one point of a second set of points, the excitation points of the first and second set being distinct and the amplification chain of the first type being different from the amplification chain of the second type so that they exhibit different amplification properties.Type: GrantFiled: February 1, 2018Date of Patent: April 27, 2021Assignees: THALES, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Patrick Garrec, Anthony Ghiotto, Gwenaël Morvan
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Patent number: 10989665Abstract: A method for detecting and quantifying additives in a complex aqueous fluid, and a method for detecting an inhibitor of mineral deposition or corrosion, injected in a gas or oil well. The invention also relates to a developer solution including a lanthanide and a chelating agent for detecting said additives or inhibitors.Type: GrantFiled: June 17, 2015Date of Patent: April 27, 2021Assignees: TOTAL SA, UNIVERSITE CLAUDE BERNARD LYON 1 (UCBL), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Christian Hurtevent, Salima Baraka-Lokmane, Olivier Tillement, Arthur Marais, Mattéo Martini, Mahmoud Ould-Metidji, Francisco Vasquez Velado, Florian Lepoivre
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Patent number: 10989484Abstract: Disclosed is an installation for generating electricity from a heat source, for disconnecting the production of electricity from the source of heat. The main characteristic of such installation is that it includes a thermochemical storage device coupled to a power cycle, the storage device consisting of a reactor in which produces a reversible sorption process and an evaporator and a condenser, at least one of the components of the thermochemical device being coupled mass and/or thermal to at least one element of the power cycle.Type: GrantFiled: December 18, 2017Date of Patent: April 27, 2021Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTESInventors: Nathalie Mazet, Sylvain Mauran, Pierre Neveu, Driss Stitou, Lingai Luo, Yilin Fan
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Publication number: 20210114200Abstract: Movement amplifying actuation device (100) comprising at least two piezoelectric beams (101, 102, 103), one beam (101) being attached at a fixed point (111), and at least one hinge (131, 132) connecting a first beam (101, 102) and a second beam (102, 103) between them. Each hinge comprises: a first flexible portion connected to the first beam, a second flexible portion connected to the second beam, a first rigid portion connecting the first and second flexible portions, a second rigid portion capable of being positioned against a fixed point (112, 113), and third flexible portion connecting the second beam to the second rigid portion at a pivot point of said second beam such that the assembly formed by the second rigid portion and the second beam forms a lever around said pivot point. Said flexible and rigid portions form a single piece.Type: ApplicationFiled: July 27, 2018Publication date: April 22, 2021Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE FRANCHE-COMTE, ECOLE NATIONALE SUPERIEURE DE MECANIQUE ET DES MICROTECHNIQUESInventors: Sergio Lescano, Nicolas Andreff, Micky Rakotondrabe, Kanty Rabenorosoa, Brahim Tamadazte, Clément Bouderlique
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Publication number: 20210115085Abstract: A continuous, solvent-free and non-enzymatic method for synthesizing a compound of formula (I): Ra-POLYPEP-Rc (I) wherein: POLYPEP is a poly-amino acid compound, Ra and Rc are as specified, the method including the steps of: a) feeding an extrusion reactor with (1) a compound of formula (II) Ra-PEPNt-Rg (II) wherein; PEPNt is a mono- or a poly-amino acid compound, Ra and Rg are as specified, and (2) a compound of formula (III) H-PEPCt-Rc (III) wherein: PEPCt is a mono- or a poly-amino acid compound, and Rc is as defined in the absence of any solvent, so that the compound of formula (II) and the compound of formula (III) react together for generating a compound of formula (I), and b) collecting the compound of formula (I) from the extrusion reactor.Type: ApplicationFiled: February 12, 2019Publication date: April 22, 2021Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER, ECOLE DES MINES D'ALES, ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELSInventors: Yves YEBOUE, Benjamin GALLARD, Nicolas LE MOIGNE, Frédéric LAMATY, Jean MARTINEZ, Thomas-Xavier METRO
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Patent number: 10981912Abstract: A macrocycle compound of general formula (X) in which Y1 represents a C(O)OH group or a group of formula (II)Type: GrantFiled: October 21, 2019Date of Patent: April 20, 2021Assignees: GUERBET, UNIVERSITE DE BRETAGNE OCCIDENTALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Mariane Le Fur, Raphaël Tripier, Olivier Rousseaux, Maryline Beyler
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Patent number: 10980873Abstract: The invention relates to a genetically modified infectious measles virus derived from a live-attenuated measles virus strain, in which the gene encoding the viral accessory C protein has been knocked out (MV-deltaC). It concerns in particular the use of said genetically modified infectious MV-deltaC in the treatment of malignant tumour or cancer conditions, and for the preparation of agents or compositions for such treatment.Type: GrantFiled: June 3, 2019Date of Patent: April 20, 2021Assignees: INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE NANTESInventors: Frédéric Tangy, Marc Gregoire, Jean-François Fonteneau, Jean-Baptiste Guillerme, Chantal Combredet
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Patent number: 10980404Abstract: The invention relates to a method for producing an image numerical classifier, to automatically determine the visualization quality of endoscopy videocapsule images of segments of the digestive tract, comprising a step of acquiring a video in the digestive tract by a videocapsule; a step of extracting images from the video; a so-called “ground truth” step of clinically evaluating the visualization quality of the images based on medical criteria, a step of selecting an initial set of “adequate” visualization images and “inadequate” visualization images, a step of calculating at least one numerical parameter relating to at least one of the medical criteria, a statistical machine learning step to produce the numerical classifier.Type: GrantFiled: March 13, 2019Date of Patent: April 20, 2021Assignees: ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, SORBONNE UNIVERSITÉ, ÉCOLE NATIONALE SUPÉRIEURE DE L'ÉLECTRONIQUE ET DE SES APPLICATIONS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CY CERGY PARIS UNIVERSITÉInventors: Xavier Dray, Aymeric Histace