Abstract: According to a first aspect, the present disclosure relates to a digital holography device (100) for full-field blood flow imaging of ocular vessels of a field of view of a layer (11) of the eye (10). The device comprises an optical source (101) configured for the generation of an illuminating beam (Eobj) and a reference beam (ELO), and a detector (135) configured to acquire a plurality of interferograms (I(x,y,t)) wherein an interferogram is defined as the signal resulting from the interference between the said reference beam (ELO) and a part of said illuminating beam (Eobj) that is backscattered from said layer (11).
Type:
Application
Filed:
December 30, 2019
Publication date:
July 1, 2021
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), SORBONNE UNIVERSITE
Abstract: A new unequal-error-protection method that is based on using a particular parity-check-matrix structure for LDPC codes.
Type:
Grant
Filed:
June 10, 2020
Date of Patent:
June 29, 2021
Assignees:
THALES, CENTRE NATIONAL D'ETUDES SPATIALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, TESA TELECOM SPATIALES AERONAUTIQUES
Inventors:
Lorenzo Ortega Espluga, Charly Poulliat, Hanaa Al Bitar, Marie-Laure Boucheret, Marion Aubault
Abstract: The invention relates to a method for manufacturing a metal, ceramic, or composite part (PF) by flash sintering, which comprises simultaneously applying, inside a die (M), a uniaxial pressure and an electric current to a device containing a powder constituent material, said uniaxial pressure being applied by means of at least two pistons (P1, P2) which slide toward one another inside said die and each of which has a bearing surface (F1, F2) contacting said material, said bearing surfaces engaging so as to define the shape of the part to be manufactured, characterised in that: said part has a complex shape, including at least one first slender portion (V), such as a rod, plate, bevel, or shell, and a second portion (B), such as a base, plinth, or solid part, which is not slender in the slender direction of said first portion, and in that said uniaxial pressure is applied in a direction (z) substantially parallel to the smallest dimension of said first portion of the part, or to one of the two smallest dimensio
Type:
Grant
Filed:
March 29, 2012
Date of Patent:
June 29, 2021
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Alain Couret, Jean-Philippe Monchoux, Lise Durand, Houria Jabbar, Thomas Voisin
Abstract: A lighting device for total-internal-reflection fluorescence microscopy includes a substrate that is transparent to light, having a refractive index higher than that of water; a light-emitting device arranged in the interior of the substrate, suitable for emitting light radiation in the direction of a surface of the substrate, the light-emitting device being arranged such that at least one portion of the radiation reaches the surface with an angle of incidence larger than or equal to a critical angle of total internal reflection for an interface between the substrate and water; and at least one opaque mask, arranged in the interior or on the surface of the substrate so as to intercept a portion of the radiation that, in the absence of the mask, would reach the surface with an angle of incidence smaller than the critical angle. A lighting device to total-internal-reflection fluorescence microscopy is provided.
Type:
Grant
Filed:
May 23, 2017
Date of Patent:
June 29, 2021
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Alejandro Giacomotti, Maia Brunstein, Andrea Cattoni, Sophie Bouchoule, Benjamin Damilano, Denis Lefebvre
Abstract: A system for measuring the distance of an obstacle, in which an optical flow is measured radially while rotating along a circle in a plane intersecting the obstacle; and the distance of the obstacle is determined according to the amplitude of the optical flow, the radius of the circle, and the speed of rotation.
Type:
Grant
Filed:
October 5, 2017
Date of Patent:
June 22, 2021
Assignees:
UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Stephane Marie Vincent Viollet, Fabien Thierry Alain Colonnier, Erik Vanhoutte
Abstract: A method for preparing a Na3V2(PO4)2F3 material, including at least the steps: a) reducing the vanadium oxide, V2O5, under a reducing atmosphere in the absence of elementary carbon and in the presence of at least one phosphate anion precursor in order to form vanadium phosphate, VPO4; and b) exposing, under an inert atmosphere, a mixture of the VPO4 material obtained in step a) with an effective amount of sodium fluoride, NaF, and at least one hydrocarbon- and oxygen-containing compound which is a source of elementary carbon, to temperature conditions that are favourable for calcining said mixture so as to form said Na3V2(PO4)2F3 compound. Also, a related electrode material, an electrode and a secondary sodium battery using the presented material.
Type:
Grant
Filed:
October 13, 2016
Date of Patent:
June 22, 2021
Assignees:
COMMISSARIAT A L'ENERGIE ATOMIQUE ETAUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE PICARDIE JULES VERNES
Abstract: Disclosed are polypeptides including at least one vinculin binding sites, to nucleic acid sequences encoding thereof and to their use for treating a proliferation and/or adhesion related disease.
Type:
Grant
Filed:
September 29, 2016
Date of Patent:
June 22, 2021
Assignees:
PARIS SCIENCES ET LETTRES—QUARTER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE AL RECHERCHE MÉDICALE)
Inventors:
Guy Tran Van Nhieu, Cesar Valencia-Gallardo, Nicole Quenech'Du
Abstract: For the cosmetic field, omniphobic cosmetic pigments under the form of a core shell structure: the core is or includes of a metal oxide on which is adsorbed poly(?-(1?4)-D-glucosamine) chains; the chains being acetylated, or partially or totally deacetylated. Also, the process for manufacturing the omniphobic cosmetic pigments, including: (i) preparing an acidic aqueous solution including metal oxide particles and a poly (?-(1?4)-D-glucosamine), the poly (?-(1?4)-D-glucosamine) being acetylated, or partially or totally deacetylated; and (ii) increasing the pH until 12, of the solution obtained at step (i) in order to obtain the adsorption of said poly (?-(1?4)-D-glucosamine on the metal oxide particles and the precipitation of the resulting metal oxide particles coated with the poly (?-(1?4)-D-glucosamine.
Type:
Grant
Filed:
November 15, 2019
Date of Patent:
June 22, 2021
Assignees:
COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, MIYOSHI EUROPE S.A.S.
Abstract: The use of differentiation marker CD89 for the detection of cellular reservoirs of a mammalian immunodeficiency virus. Also the use of the differentiation marker CD89 for making a prognosis, diagnosing a remission, and evaluating the efficacy of treatment of the mammalian immunodeficiency. A multi-specific antibody that recognizes both at least one epitope of CD89 and at least one characteristic of the lymphocyte cells, a composition including the antibody, and the use of the antibody for treatment.
Type:
Grant
Filed:
September 30, 2017
Date of Patent:
June 22, 2021
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE MONTPELLIER
Inventors:
Monsef Benkirane, Gael Petitjean, Benjamin Descours
Abstract: The invention discloses a photocathode comprising an amorphous substrate such as a glass substrate (110) presenting an input face that will receive incident photons and a back face opposite the front face. Nanowires (120) made from at least one III-V semiconducting material are deposited on the back face of the substrate and extend from this face in a direction away from the front face. The invention also relates to a method for manufacturing such a photocathode by MBE.
Type:
Grant
Filed:
May 29, 2017
Date of Patent:
June 22, 2021
Assignees:
PHOTONIS FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Claude Alibert, Moustapha Conde, Jean-Christophe Harmand, Théo Jegorel
Abstract: The disclosure pertains to the field of molecular means capable of binding calcium, in particular peptides which are calcium chelators, appropriate for use in vitro or in vivo and preferably capable of targeting specific cellular compartments. Polypeptide comprising a first calcium-binding domain, a peptide linker and a second calcium binding domain, wherein the first and second binding domains are linked through the peptide linker, and wherein: the first calcium-binding domain and the second calcium binding domain each comprise at least one calcium-binding site derived from a EF-hand motif; and, the first calcium-binding domain and the second calcium binding domain differ in at least one calcium-binding site.
Type:
Application
Filed:
November 2, 2018
Publication date:
June 17, 2021
Applicants:
SORBONNE UNIVERSITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Abstract: The present invention is directed to a dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection. The present invention provides means, in particular polynucleotides, vectors, cells and methods to produce vectors expressing said chimeric polyepitopes, in particular vectors consisting of recombinant measles virus (MV) particles. The present invention also relates to the use of the recombinant MV particles, in particular under the form of a composition or of a vaccine, for the prevention and/or treatment of a dengue virus infection.
Type:
Grant
Filed:
March 21, 2019
Date of Patent:
June 15, 2021
Assignees:
INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT PASTEUR DU CAMBODGE
Inventors:
Frederic Tangy, Anavaj Sakuntabhai, Etienne Simon-Loriere, Claude Roth, Philippe Buchy
Abstract: The present invention relates to low temperature process for preparing nanoparticles of porous crystalline Fe-, Al- or Ti-based MOF carboxylate materials with low polydispersity index, and uses thereof, particularly as catalyst support for carrying out heterogeneously catalyzed chemical reactions, or as gas storage/separation/purification material, or as matrix for encapsulating active principles (medicine, cosmetics).
Type:
Grant
Filed:
January 29, 2018
Date of Patent:
June 15, 2021
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE VERSAILLES—SAINT-QUENTIN-EN-YVELINES
Abstract: The present invention relates to the technical field of composite materials comprising a thermosetting polymer matrix in which thermoplastic polymer and/or elastomer particles are dispersed. More precisely, the invention relates to a novel type of polymeric material obtained by using a particular ionic liquid as cross-linking agent for an epoxy resin mixed with a thermoplastic polymer and/or an elastomer. The invention also relates to a process for manufacturing said composite material and uses thereof, notably in the aeronautical, aerospace, automotive, maritime, wind power, electronics, or sports and leisure sectors.
Type:
Grant
Filed:
May 22, 2017
Date of Patent:
June 15, 2021
Assignees:
UNIVERSITE CLAUDE BERNARD LYON 1, UNIVERSITÉ JEAN MONNET SAINT ETIENNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON
Abstract: A filter for the filtration of a fluid, such as a liquid, includes or composed of a support element made of a porous ceramic material, the element having a tubular or parallelepipedal shape delimited by an external surface and including, in its internal portion, a set of adjacent channels with axes parallel to one another and separated from one another by walls of the porous inorganic material, wherein at least a portion of the channels and/or at least a portion of the external surface are covered with a porous separating membrane layer, wherein the layer is made of a material essentially composed of sintered grains of silicon carbide (SiC), and the weight content of elemental oxygen of the layer is less than 0.5%.
Type:
Grant
Filed:
December 18, 2015
Date of Patent:
June 15, 2021
Assignees:
SAINT-GOBAIN CENTRE DE RECHERCHES ET D'ETUDES EUROPEAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER
Abstract: A method for generating ultrashort pulses includes directing a master beam having ultrashort pulses and at least one slave beam through an optical gate material. The intensity of the slave beam upstream of the optical gate material is lower than that of the master beam upstream of the optical gate material. The optical gate material and the pulses of the master beam are chosen to induce a Kerr effect when the master beam passes through the optical gate material, the Kerr effect producing a modulation of the phase of the slave beam in association with pulses of the master beam when the slave beam passes through the optical gate material. The modulation of the phase of the slave beam is transformed into a modulation of the amplitude thereof using a complementary optical device to generate a slave beam downstream of the optical gate material having ultrashort pulses.
Type:
Application
Filed:
April 19, 2019
Publication date:
June 10, 2021
Applicants:
ECOLE POLYTECHNIQUE, INSTITUT D'OPTIQUE GRADUATE SCHOOL (IOGS), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SACLAY
Abstract: An electronic device for measuring a speed of flow of a fluid that includes at least two electroacoustic transducers adapted for emitting and/or receiving acoustic signals through the flow of the fluid, the electronic device being adapted for determining a measurement of the speed of flow of the fluid from the characteristics of an acoustic signal emitted and one or more acoustic signals received, these received acoustic signals corresponding to reflections of the emitted acoustic signal.
Type:
Application
Filed:
April 19, 2019
Publication date:
June 3, 2021
Applicants:
UNIVERSITE DU MANS, ASSOC TRANSFERTS TECHNOLOGIES MANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors:
Jacques EMERY, Mohammed TABELLOUT, Charfeddine Mechri
Abstract: The present invention relates to an aqueous extract useful notably for the regeneration of human or animal cells, notably mammalian cells, comprising an aqueous extract free of any insoluble solid debris of ground planarian organisms having a regeneration capacity, containing at least the intracellular components of the cells of said organisms of a cell lysate of said cells of said organisms.
Type:
Application
Filed:
May 30, 2018
Publication date:
June 3, 2021
Applicants:
FONDATION MEDITERRANEE INFECTION, UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE - HOPITAUX DE MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
Inventors:
Eric GHIGO, Eric CHABRIERE, Michel DRANCOURT, Vincent BONNIOL