Abstract: A luminescent solar concentrator (LSC) comprising a metal-free emitter. The emitter may for example be carbon-based. In particular, the emitter may comprise colloidal carbon quantum dots, also called C-dots or C-QDs or C-dots. In embodiments of the invention, the surface of the C-dots is modified.
Type:
Application
Filed:
February 16, 2018
Publication date:
July 23, 2020
Applicants:
INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA
Inventors:
Yufeng ZHOU, Daniele BENETTI, Xin TONG, Lei JIN, Zhiming M. WANG, Dongling MA, Haiguang ZHAO, Federico ROSEI
Abstract: According to one aspect, the invention concerns an optical imaging device (20) for an object (OBJ) by off-axis holography comprising a light source (21) adapted for emitting an illumination wave (EI) on the object, in transmission or reflection, and an assembly formed by one or more thick Bragg gratings (22) for receiving a wave (EO) coming from the object thus illuminated and for deflecting a first component (ER) of the wave coming from the object, called the reference wave, and to allow a second component (ES) of the wave coming from the object, called the signal wave, to pass without deflection in such a way that the deflected reference wave presents predetermined deflection angles with respect to the non-deflected signal wave defined in two perpendicular planes.
Type:
Application
Filed:
March 30, 2018
Publication date:
July 23, 2020
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
Abstract: A method for preparing a nanoporous silica sol-gel matrix containing at least one amine reactant selected from hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, tetraethylenepentamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof, said method including the following steps: a) synthesising a gel from tetramethoxysilane or from a mixture of tetramethoxysilane and another organosilicon precursor selected from among phenyltrimethoxysilane, phenyltriethoxysilane, a fluoroalkyltrimethoxysilane, a fluoroalkyltriethoxysilane, a chloroalkylmethoxysilane, a chloroalkylethoxysilane, an alkyltrimethoxysilane, an alkyltriethoxysilane, an aminopropyltriethoxysilane and the mixtures thereof, the synthesis being performed in an aqueous medium at a temperature ranging from 10 to 70° C.
Type:
Application
Filed:
July 27, 2018
Publication date:
July 23, 2020
Applicants:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -
Abstract: The invention relates to functionalised dioxaborolane or dioxaborinane derivatives of formula (I), wherein R1 is covalently bonded to the boron atom by a carbon atom; one of R2, R3, R?3 or R4 is a radical of formula —X; or one of R1, R2, R3, R?3 or R4 is a radical of formula —X; and X is a functionalised radical. The invention relates to the method for preparing same and the uses thereof.
Type:
Application
Filed:
May 30, 2017
Publication date:
July 23, 2020
Applicants:
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Abstract: A prosthetic implant includes a cavity that opens at an outer face of the prosthetic implant, the cavity forming a housing for receiving: a printed circuit including a radio tag; and a cover which closes the cavity at least partially when positioned on the implant in a so-called closed position, the radio tag and printed circuit being removably housed in the cavity.
Type:
Grant
Filed:
July 20, 2017
Date of Patent:
July 21, 2020
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, BONETAG
Abstract: Described herein are anti-CD277 antibodies which: activates or inhibit the cytolytic function of V?9/V?2 T cells, and/or costimulates T cells together with CD3-TCR, and/or costimulates T cells in addition to CD28-B7 costimulation, and/or increases the activity and/or survival of monocytes and dendritic cells. The use of said antibodies in therapy is also described.
Type:
Grant
Filed:
February 22, 2019
Date of Patent:
July 21, 2020
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, UNIVERSITE D'AIX MARSEILLE, UNIVERSITE DE NANTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
Inventors:
Daniel Olive, Marc Bonneville, Emmanuel Scotet, Christelle Harly, Yves Guillaume
Abstract: The invention relates to a method for preparing a material based on an aluminosilicate selected from barium aluminosilicate BAS, barium-strontium aluminosilicate BSAS, and strontium aluminosilicate SAS, said aluminosilicate consisting of aluminosilicate with a hexagonal structure, characterised in that it includes a single sintering step in which a mixture of powders of precursors of said aluminosilicate, including an aluminium hydroxide Al(OH)3 powder, are sintered by a hot-sintering technique with a pulsed electric field SPS; whereby a material based on an aluminosilicate, said aluminosilicate consisting of an aluminosilicate with a hexagonal structure is obtained. The material based on an aluminosilicate prepared by said method can be used in a method for preparing a composite material consisting of an aluminosilicate matrix reinforced by reinforcements made of metalloid or metal oxide.
Type:
Grant
Filed:
January 21, 2016
Date of Patent:
July 21, 2020
Assignees:
COMMISSARIAT ÀL'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Alexandre Allemand, Philippe Belleville, Yann Le Petitcorps, Romain Billard, Mickael Dolle
Abstract: The present invention relates to a compound of formula (I): wherein A and A? independently represent a phenylene group or a pyridylene group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is a 2-pyridyl group, 3-pyridyl group, a 4-pyridyl group, a 2-pyrimidinyl group, a 4-pyrimidinyl group or a 5-pyrimidinyl group; R4 is a carbonyl group or a sulfonyl group; and R5 is a —NH—(CH2)a—NR6R7 group or a 4-methylpiperazinyl group, with a being an integer from 1 to 4, R6 and R7 representing independently a (C1-C4)alkyl group, or R6 and R7 together with the nitrogen atom to which they are linked forming a heterocycle group which is chosen among a 4-methylpiperazinyl group, a morpholino group, a pyrrolidinyl group and a piperidino group; or any one of its pharmaceutically acceptable salt.
Type:
Grant
Filed:
April 5, 2018
Date of Patent:
July 21, 2020
Assignees:
ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
Abstract: Disclosed are new compounds of formulae: Wherein: R1 and R2 can be independently H; a C1 to C6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R1,R2 together with the carbon C-6 can be a cyclopentylidene or cyclohexylidene; each of these groups being substituted or not; and R3 can be a C1 to C6 alkyl including methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl; or aryl including phenyl, methylphenyl, ethylphenyl, each of these groups being substituted or not. The invention also relates to their method of manufacture and their use for the synthesis of Ara-N3, Kdo-N3 and 4eKdo-N3.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
July 21, 2020
Assignee:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Inventors:
Boris Vauzeilles, Jordi Mas Pons, Aurèlie Baron
Abstract: A method for estimating a stiffness of a deformable part of a system including a four-photodiode detector for analyzing at least one characteristic of a sample. The method includes receiving the signals recorded by the four photodiodes, calculating the resultant signals from the recorded signals, calculating a cross-correlation of the resultant signals calculated for obtaining an intercorrelated signal, estimating the stiffness of the deformable part depending on the intercorrelated signal.
Type:
Grant
Filed:
December 29, 2016
Date of Patent:
July 21, 2020
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
Abstract: The present invention relates to a method for screening a compound useful for treating or preventing a viral infection or a virus-related condition in an individual, comprising at least the steps of: a) determining the ability of a candidate compound to promote the interaction between CBP20 and CBP80 in a sample, and b) selecting the candidate compound that is determined to promote said interaction at step a). The present invention further relates to a method for screening a compound useful for treating or preventing a viral infection or virus-related condition in an individual, comprising at least the steps of: a) determining the ability of a candidate compound to interact with CBP20 or CBP80 in a sample, and b) selecting the candidate compound that is determined to interact with CBP20 or CBP80 at step a).
Type:
Grant
Filed:
February 19, 2016
Date of Patent:
July 21, 2020
Assignees:
ABIV AX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
Abstract: A method is provided for detecting a fluorescent species that is reversibly photoswitchable at high frequency, and more precisely to a method for detecting at least one reversibly photoswitchable fluorescent species, including a step consisting in illuminating a sample containing a reversibly photoswitchable fluorescent species with a first illuminating light beam, of wavelength ?1, and periodically modulated at an angular frequency ?, and with a second illuminating light beam of wavelength ?2 different from ?1, which is periodically modulated at the angular frequency ?, the second illuminating light beam being modulated in antiphase with respect to the first illuminating light beam.
Type:
Grant
Filed:
August 10, 2017
Date of Patent:
July 21, 2020
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, ECOLE NORMALE SUPERIEURE
Inventors:
Jérôme Querard, Thomas Le Saux, Ludovic Jullien
Abstract: An optical guide for a near-eye display device includes a first guide element having a light input zone and a second guide element having an output zone. The first guide element is superimposed on the second guide element. The optical guide also includes an optical coupling system between the first guide element and the second guide element, and the first and second guide elements have, on the first part of their length, a mutual spacing so as to delimit a thin layer of air between said guide elements extending between a first longitudinal end of the guide elements and the optical coupling system. The optical coupling system, located at a second longitudinal end of the first and second guide elements, includes a single-piece portion of the guide elements, associated with an optical reflection member to propagate the beams of light from the input zone toward the output zone.
Type:
Grant
Filed:
January 12, 2017
Date of Patent:
July 21, 2020
Assignees:
UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DES SCIENES APPLIQUEES
Abstract: Some embodiments are directed to a generating device, including a pulse laser source providing primary photons having at least one wavelength, shaping device(s) acting on the primary photons to provide an input beam, a nonlinear crystal, and controller(s) generating, in the nonlinear crystal, at least one electric field that is synchronous with the input beam and suitable for inducing a phase mismatching in the nonlinear crystal through an electro-optical effect, in order to convert the primary photons of the input beam into secondary photons having wavelengths belonging to a supercontinuum.
Type:
Grant
Filed:
January 20, 2017
Date of Patent:
July 21, 2020
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGES
Inventors:
Katarzyna Krupa, Badr Shalaby, Alexis Labruyère, Alessandro Tonello, Vincent Couderc
Abstract: The present invention relates to a recombinant yeast cell comprising a gene encoding a protein exhibiting lactyl-CoA synthase activity and a gene encoding a protein exhibiting lactyl-CoA polymerase activity, said recombinant cell having the ability of producing polylactic acid (PLA), and the uses thereof.
Type:
Grant
Filed:
December 15, 2016
Date of Patent:
July 21, 2020
Assignees:
CARBIOS, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, A'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Simon Dusseaux, Sophie Lajus, Vinciane Borsenberger, Jonathan Verbeke, Florence Bordes, Alain Marty, Jean-Marc Nicaud, Athanasios Beopoulos
Abstract: A method for handling, in a microfluidic system, microdrops which include samples, including the steps of forming, in an oil, microdrops of an aqueous solution containing a sample, the oil and/or the aqueous solution containing a sample including a gelling agent; trapping the microdrops by means of surface-tension traps pre-arranged in a trapping area; and at least partially gelling the oil in the trapping area and/or at least partially gelling the trapped microdrops.
Type:
Grant
Filed:
October 17, 2014
Date of Patent:
July 14, 2020
Assignees:
ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Charles Baroud, Gabriel Amselem, Sébastien Sart, Raphaël Tomasi
Abstract: The present invention relates to ex vivo method for producing outer membrane vesicles (OMVs) by expression or overexpression of the hemolysin F gene (hlyF) in gram-negative bacterium.
Type:
Grant
Filed:
April 7, 2015
Date of Patent:
July 14, 2020
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITÉ PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
Inventors:
Eric Oswald, Patricia Martin, Kazunori Murase
Abstract: The present invention relates to compounds, ligands, and/or complexes that are useful in medical imaging and/or in therapy, especially in cancer treatment. The present invention also relates to a pharmaceutical composition comprising said compounds, ligands, and/or complexes that are useful for medical imaging, targeting, and/or treatment of cancers. The present invention also relates to a process for preparing these compounds, ligands, and/or complexes.
Type:
Grant
Filed:
December 23, 2016
Date of Patent:
July 14, 2020
Assignees:
GUERBET, UNIVERSITE DE BRETAGNE OCCIDENTALE, CENTRAL NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Mariane Le Fur, Raphaël Tripier, Olivier Rousseaux, Maryline Beyler
Abstract: The invention relates to methods and compositions comprising a macrophage colony stimulating factor (M-CSF) polypeptide or an agonist of the M-CSF receptor for preventing or treating myeloid cytopenia and related complications (such as infections) in a patient in need thereof (such as a patient undergoing hematopoietic stem cell transplantation).
Type:
Grant
Filed:
April 9, 2014
Date of Patent:
July 14, 2020
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX-MARSEILLE
Abstract: An instrumented interface for quantifying at least one physiological parameter of the upper limbs of a person, capable of being secured to a gripping device, and including at least one gripping system which the person can hang from, the instrumented interface including at least one force sensor which measures a deformation of the interface when a person exerts a force on the interface via the one gripping device, and is capable of producing a value that translates a force value.
Type:
Grant
Filed:
May 25, 2016
Date of Patent:
July 7, 2020
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX MARSEILLE