Patents Assigned to SCIENTIFIQUE (CNRS)
  • Publication number: 20200235254
    Abstract: A luminescent solar concentrator (LSC) comprising a metal-free emitter. The emitter may for example be carbon-based. In particular, the emitter may comprise colloidal carbon quantum dots, also called C-dots or C-QDs or C-dots. In embodiments of the invention, the surface of the C-dots is modified.
    Type: Application
    Filed: February 16, 2018
    Publication date: July 23, 2020
    Applicants: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA
    Inventors: Yufeng ZHOU, Daniele BENETTI, Xin TONG, Lei JIN, Zhiming M. WANG, Dongling MA, Haiguang ZHAO, Federico ROSEI
  • Publication number: 20200233378
    Abstract: According to one aspect, the invention concerns an optical imaging device (20) for an object (OBJ) by off-axis holography comprising a light source (21) adapted for emitting an illumination wave (EI) on the object, in transmission or reflection, and an assembly formed by one or more thick Bragg gratings (22) for receiving a wave (EO) coming from the object thus illuminated and for deflecting a first component (ER) of the wave coming from the object, called the reference wave, and to allow a second component (ES) of the wave coming from the object, called the signal wave, to pass without deflection in such a way that the deflected reference wave presents predetermined deflection angles with respect to the non-deflected signal wave defined in two perpendicular planes.
    Type: Application
    Filed: March 30, 2018
    Publication date: July 23, 2020
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPÉRIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS
    Inventors: Michael Atlan, Jean-Pierre Huignard
  • Publication number: 20200230542
    Abstract: A method for preparing a nanoporous silica sol-gel matrix containing at least one amine reactant selected from hydroxylamine, methylhydroxylamine, tertbutylhydroxylamine, methoxyamine, tetraethylenepentamine, dicarboxylic acid dihydrazides, particularly adipic acid dihydrazide, and the salts thereof, said method including the following steps: a) synthesising a gel from tetramethoxysilane or from a mixture of tetramethoxysilane and another organosilicon precursor selected from among phenyltrimethoxysilane, phenyltriethoxysilane, a fluoroalkyltrimethoxysilane, a fluoroalkyltriethoxysilane, a chloroalkylmethoxysilane, a chloroalkylethoxysilane, an alkyltrimethoxysilane, an alkyltriethoxysilane, an aminopropyltriethoxysilane and the mixtures thereof, the synthesis being performed in an aqueous medium at a temperature ranging from 10 to 70° C.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 23, 2020
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -
    Inventors: Thu-Hoa TRAN-THI, Ana BORTA, Mickael GINEYS, Marie-Pierre SOM, Frédéric HAMMEL
  • Publication number: 20200231605
    Abstract: The invention relates to functionalised dioxaborolane or dioxaborinane derivatives of formula (I), wherein R1 is covalently bonded to the boron atom by a carbon atom; one of R2, R3, R?3 or R4 is a radical of formula —X; or one of R1, R2, R3, R?3 or R4 is a radical of formula —X; and X is a functionalised radical. The invention relates to the method for preparing same and the uses thereof.
    Type: Application
    Filed: May 30, 2017
    Publication date: July 23, 2020
    Applicants: ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Ludwik LEIBLER, Renaud NICOLAY
  • Patent number: 10716506
    Abstract: A prosthetic implant includes a cavity that opens at an outer face of the prosthetic implant, the cavity forming a housing for receiving: a printed circuit including a radio tag; and a cover which closes the cavity at least partially when positioned on the implant in a so-called closed position, the radio tag and printed circuit being removably housed in the cavity.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: July 21, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, BONETAG
    Inventors: Arnaud Vena, Brice Sorli, Stéphan Cahuzac, Stéphane Naudi
  • Patent number: 10716838
    Abstract: Described herein are anti-CD277 antibodies which: activates or inhibit the cytolytic function of V?9/V?2 T cells, and/or costimulates T cells together with CD3-TCR, and/or costimulates T cells in addition to CD28-B7 costimulation, and/or increases the activity and/or survival of monocytes and dendritic cells. The use of said antibodies in therapy is also described.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: July 21, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, UNIVERSITE D'AIX MARSEILLE, UNIVERSITE DE NANTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
    Inventors: Daniel Olive, Marc Bonneville, Emmanuel Scotet, Christelle Harly, Yves Guillaume
  • Patent number: 10717656
    Abstract: The invention relates to a method for preparing a material based on an aluminosilicate selected from barium aluminosilicate BAS, barium-strontium aluminosilicate BSAS, and strontium aluminosilicate SAS, said aluminosilicate consisting of aluminosilicate with a hexagonal structure, characterised in that it includes a single sintering step in which a mixture of powders of precursors of said aluminosilicate, including an aluminium hydroxide Al(OH)3 powder, are sintered by a hot-sintering technique with a pulsed electric field SPS; whereby a material based on an aluminosilicate, said aluminosilicate consisting of an aluminosilicate with a hexagonal structure is obtained. The material based on an aluminosilicate prepared by said method can be used in a method for preparing a composite material consisting of an aluminosilicate matrix reinforced by reinforcements made of metalloid or metal oxide.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: July 21, 2020
    Assignees: COMMISSARIAT ÀL'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Alexandre Allemand, Philippe Belleville, Yann Le Petitcorps, Romain Billard, Mickael Dolle
  • Patent number: 10717724
    Abstract: The present invention relates to a compound of formula (I): wherein A and A? independently represent a phenylene group or a pyridylene group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is a 2-pyridyl group, 3-pyridyl group, a 4-pyridyl group, a 2-pyrimidinyl group, a 4-pyrimidinyl group or a 5-pyrimidinyl group; R4 is a carbonyl group or a sulfonyl group; and R5 is a —NH—(CH2)a—NR6R7 group or a 4-methylpiperazinyl group, with a being an integer from 1 to 4, R6 and R7 representing independently a (C1-C4)alkyl group, or R6 and R7 together with the nitrogen atom to which they are linked forming a heterocycle group which is chosen among a 4-methylpiperazinyl group, a morpholino group, a pyrrolidinyl group and a piperidino group; or any one of its pharmaceutically acceptable salt.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: July 21, 2020
    Assignees: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
    Inventors: Pierre Roux, Florence Mahuteau, Romain Najman, Gilles Gadea, Jamal Tazi, Didier Scherrer, Carsten Brock, Nathalie Cahuzac
  • Patent number: 10717718
    Abstract: Disclosed are new compounds of formulae: Wherein: R1 and R2 can be independently H; a C1 to C6 alkyl including methyl, ethyl, propyl, butyl; aryl including phenyl, para-methoxyphenyl; or R1,R2 together with the carbon C-6 can be a cyclopentylidene or cyclohexylidene; each of these groups being substituted or not; and R3 can be a C1 to C6 alkyl including methyl, ethyl, propyl, isopropyl, butyl, isobutyl, tert-butyl, pentyl; or aryl including phenyl, methylphenyl, ethylphenyl, each of these groups being substituted or not. The invention also relates to their method of manufacture and their use for the synthesis of Ara-N3, Kdo-N3 and 4eKdo-N3.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: July 21, 2020
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Boris Vauzeilles, Jordi Mas Pons, Aurèlie Baron
  • Patent number: 10718697
    Abstract: A method for estimating a stiffness of a deformable part of a system including a four-photodiode detector for analyzing at least one characteristic of a sample. The method includes receiving the signals recorded by the four photodiodes, calculating the resultant signals from the recorded signals, calculating a cross-correlation of the resultant signals calculated for obtaining an intercorrelated signal, estimating the stiffness of the deformable part depending on the intercorrelated signal.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: July 21, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1
    Inventor: Ludovic Bellon
  • Patent number: 10718770
    Abstract: The present invention relates to a method for screening a compound useful for treating or preventing a viral infection or a virus-related condition in an individual, comprising at least the steps of: a) determining the ability of a candidate compound to promote the interaction between CBP20 and CBP80 in a sample, and b) selecting the candidate compound that is determined to promote said interaction at step a). The present invention further relates to a method for screening a compound useful for treating or preventing a viral infection or virus-related condition in an individual, comprising at least the steps of: a) determining the ability of a candidate compound to interact with CBP20 or CBP80 in a sample, and b) selecting the candidate compound that is determined to interact with CBP20 or CBP80 at step a).
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: July 21, 2020
    Assignees: ABIV AX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
    Inventors: Didier Scherrer, Aude Garcel, Noelie Campos, Jamal Tazi, Audrey Vautrin, Florence Mahuteau, Romain Najman, Pauline Fornarelli
  • Patent number: 10718712
    Abstract: A method is provided for detecting a fluorescent species that is reversibly photoswitchable at high frequency, and more precisely to a method for detecting at least one reversibly photoswitchable fluorescent species, including a step consisting in illuminating a sample containing a reversibly photoswitchable fluorescent species with a first illuminating light beam, of wavelength ?1, and periodically modulated at an angular frequency ?, and with a second illuminating light beam of wavelength ?2 different from ?1, which is periodically modulated at the angular frequency ?, the second illuminating light beam being modulated in antiphase with respect to the first illuminating light beam.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: July 21, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, ECOLE NORMALE SUPERIEURE
    Inventors: Jérôme Querard, Thomas Le Saux, Ludovic Jullien
  • Patent number: 10718946
    Abstract: An optical guide for a near-eye display device includes a first guide element having a light input zone and a second guide element having an output zone. The first guide element is superimposed on the second guide element. The optical guide also includes an optical coupling system between the first guide element and the second guide element, and the first and second guide elements have, on the first part of their length, a mutual spacing so as to delimit a thin layer of air between said guide elements extending between a first longitudinal end of the guide elements and the optical coupling system. The optical coupling system, located at a second longitudinal end of the first and second guide elements, includes a single-piece portion of the guide elements, associated with an optical reflection member to propagate the beams of light from the input zone toward the output zone.
    Type: Grant
    Filed: January 12, 2017
    Date of Patent: July 21, 2020
    Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DES SCIENES APPLIQUEES
    Inventors: Jianming Yang, Patrice Twardowski, Joël Fontaine
  • Patent number: 10718991
    Abstract: Some embodiments are directed to a generating device, including a pulse laser source providing primary photons having at least one wavelength, shaping device(s) acting on the primary photons to provide an input beam, a nonlinear crystal, and controller(s) generating, in the nonlinear crystal, at least one electric field that is synchronous with the input beam and suitable for inducing a phase mismatching in the nonlinear crystal through an electro-optical effect, in order to convert the primary photons of the input beam into secondary photons having wavelengths belonging to a supercontinuum.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: July 21, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGES
    Inventors: Katarzyna Krupa, Badr Shalaby, Alexis Labruyère, Alessandro Tonello, Vincent Couderc
  • Patent number: 10717996
    Abstract: The present invention relates to a recombinant yeast cell comprising a gene encoding a protein exhibiting lactyl-CoA synthase activity and a gene encoding a protein exhibiting lactyl-CoA polymerase activity, said recombinant cell having the ability of producing polylactic acid (PLA), and the uses thereof.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: July 21, 2020
    Assignees: CARBIOS, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, A'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Simon Dusseaux, Sophie Lajus, Vinciane Borsenberger, Jonathan Verbeke, Florence Bordes, Alain Marty, Jean-Marc Nicaud, Athanasios Beopoulos
  • Patent number: 10710077
    Abstract: A method for handling, in a microfluidic system, microdrops which include samples, including the steps of forming, in an oil, microdrops of an aqueous solution containing a sample, the oil and/or the aqueous solution containing a sample including a gelling agent; trapping the microdrops by means of surface-tension traps pre-arranged in a trapping area; and at least partially gelling the oil in the trapping area and/or at least partially gelling the trapped microdrops.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: July 14, 2020
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Charles Baroud, Gabriel Amselem, Sébastien Sart, Raphaël Tomasi
  • Patent number: 10709776
    Abstract: The present invention relates to ex vivo method for producing outer membrane vesicles (OMVs) by expression or overexpression of the hemolysin F gene (hlyF) in gram-negative bacterium.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: July 14, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITÉ PAUL SABATIER TOULOUSE III, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE
    Inventors: Eric Oswald, Patricia Martin, Kazunori Murase
  • Patent number: 10711001
    Abstract: The present invention relates to compounds, ligands, and/or complexes that are useful in medical imaging and/or in therapy, especially in cancer treatment. The present invention also relates to a pharmaceutical composition comprising said compounds, ligands, and/or complexes that are useful for medical imaging, targeting, and/or treatment of cancers. The present invention also relates to a process for preparing these compounds, ligands, and/or complexes.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: July 14, 2020
    Assignees: GUERBET, UNIVERSITE DE BRETAGNE OCCIDENTALE, CENTRAL NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Mariane Le Fur, Raphaël Tripier, Olivier Rousseaux, Maryline Beyler
  • Patent number: 10709762
    Abstract: The invention relates to methods and compositions comprising a macrophage colony stimulating factor (M-CSF) polypeptide or an agonist of the M-CSF receptor for preventing or treating myeloid cytopenia and related complications (such as infections) in a patient in need thereof (such as a patient undergoing hematopoietic stem cell transplantation).
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: July 14, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX-MARSEILLE
    Inventor: Michael Sieweke
  • Patent number: 10702201
    Abstract: An instrumented interface for quantifying at least one physiological parameter of the upper limbs of a person, capable of being secured to a gripping device, and including at least one gripping system which the person can hang from, the instrumented interface including at least one force sensor which measures a deformation of the interface when a person exerts a force on the interface via the one gripping device, and is capable of producing a value that translates a force value.
    Type: Grant
    Filed: May 25, 2016
    Date of Patent: July 7, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX MARSEILLE
    Inventor: Laurent Vigouroux