Patents Assigned to SCIENTIFIQUE (CNRS)
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Patent number: 10702201Abstract: An instrumented interface for quantifying at least one physiological parameter of the upper limbs of a person, capable of being secured to a gripping device, and including at least one gripping system which the person can hang from, the instrumented interface including at least one force sensor which measures a deformation of the interface when a person exerts a force on the interface via the one gripping device, and is capable of producing a value that translates a force value.Type: GrantFiled: May 25, 2016Date of Patent: July 7, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'AIX MARSEILLEInventor: Laurent Vigouroux
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Patent number: 10702860Abstract: The use, after heat treatment, of manganese accumulating plants for carrying out chemical reactions.Type: GrantFiled: July 23, 2013Date of Patent: July 7, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUESInventors: Claude Grison, Vincent Escande
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Patent number: 10705036Abstract: A spectroscopy method and system, the method comprising irradiating an object with a laser-accelerated particle beam and detecting photons emitted by the object as a result of the interaction between the laser-accelerated particle beam and the object. The system comprises a laser; a particle source, positioned at a distance from the object; and a spectrometer and a detector; wherein the particle source generates a laser-accelerated particle beam under irradiation by the laser; and the spectrometer and the detector detect photons emitted from the object under irradiation by the laser-accelerated particle beam.Type: GrantFiled: January 23, 2018Date of Patent: July 7, 2020Assignees: UNIVERSITÁ DELLA CALABRIA, INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Patrizio Antici, Marianna Barberio
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Patent number: 10703708Abstract: The present invention concerns a method of synthesizing a iodo- or astatoarene comprising the reaction of a diaryliodonium compound with a iodide or astatide salt, respectively. The invention also relates to said iodo- or astatoarene and diaryliodonium compound as such. The invention also concerns a method of synthesizing a iodo- or astatolabelled biomolecule and/or vector using said iodo- or astatoarene.Type: GrantFiled: November 24, 2016Date of Patent: July 7, 2020Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, UNIVERSITE D'ANGERS, THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICESInventors: François Guerard, Jean-François Gestin, Martin W. Brechbiel, Yong-Sok Lee
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Patent number: 10695416Abstract: The invention relates to vaccine compositions for treating and/or preventing infections by a bacterium of the Chlalmydiaceae family, said compositions comprising bacteria of the Chlamydiaceae family, which have been previously treated by at least one peptidoglycan inhibitor, or extracts of said treated bacteria.Type: GrantFiled: July 28, 2016Date of Patent: June 30, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS DIDEROT PARIS 7, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Philippe Verbeke, Colette Kanellopoulos
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Patent number: 10696995Abstract: The present invention relates to a method for producing a glycosylated synthon or a monomer. Said method includes at least one step of placing at least one glycan-saccharase in the presence of at least one hydroxylated synthon and at least one saccharose. The invention also relates to a method for producing a glyco(co)polymer, including polymerizing at least two monomers separately obtained from the enzymatic glycosylation method according to the invention, and to a method for producing a glyco(co)polymer, preferably a block glyco(co)polymer, including coupling at least two monomers separately obtained from the enzymatic glycosylation method according to the invention.Type: GrantFiled: March 17, 2016Date of Patent: June 30, 2020Assignees: INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, INSTITUT NATIONAL DES SCIENCES APPIQUEES DE TOULOUSE (INSAT), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUXInventors: Isabelle Andre, Stephane Grelier, David Guieysse, Alvaro Lafraya, Pierre Monsan, Claire Moulis, Frederic Peruch, Magali Remaud-Simeon, Marlene Vuillemin
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Patent number: 10697807Abstract: A measurement system for performing measurement by Brillouin scattering analysis, the system comprising a laser emitter device (10) configured to emit an incident wave (?0) and a reference wave (?0??B), the incident wave presenting an incident frequency (?0) and the reference wave presenting a reference frequency (?0??B), the reference frequency (?0??B) being shifted from the incident frequency (?0) by a predetermined value (?B). The system is configured to: project the incident wave (?0) into the optical fiber (25); receive in return a backscattered wave (?0??S); generate a composite wave (?0-S, 0-B) combining the backscattered wave (?0??S) and the reference wave (S0??B); and determine at least one property relating to the fiber by analyzing a Brillouin spectrum of the composite wave (?0-S, 0-B). Advantageously, the incident wave and the reference wave come from a dual-frequency vertical-cavity surface-emitting laser source (12) forming part of the laser emitter device.Type: GrantFiled: September 21, 2016Date of Patent: June 30, 2020Assignees: INSTITUT FRANCAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMENAGEMENT ET DES RESEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Aghiad Khadour, Jean-Louis Oudar
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Patent number: 10696694Abstract: The invention relates to cationic complexes made up of a lanthanide ion Ln3+ and a ligand of formula (I): with X, Y and R1 as defined in claim 1, and to the salts thereof with an anion, the solvates and hydrates thereof; with the exception of cationic complexes made up of a lanthanide ion Ln3+ and a ligand of one of formulae (I.1) or (I.4) as defined in claim 1, and the salts, solvates and hydrates thereof. The invention also relates to the use of such a complex or of a cationic complex made up of a lanthanide ion Ln3+ and a ligand of formula (I.1) or (I.4) as defined in claim 1, or of one of the salts thereof with an anion, the solvates or hydrates thereof, as an aid to the crystallisation of a biological macromolecule, as well as to crystallisation methods and methods for analysing or determining the structure of a biological macromolecule.Type: GrantFiled: December 16, 2016Date of Patent: June 30, 2020Assignees: ECOLE NORMALE SUPERIEURE LE LYON, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Oliver Maury, Eric Girard, Sylvain Engilberge, François Riobe
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Patent number: 10697965Abstract: The present invention relates to an in vitro method for determine the prognosis of the survival time of a patient suffering from a cancer comprising the steps consisting of i) determining the expression level of the couple DNMT3A/ISGF3? in a sample from said patient, ii) comparing said expression level with a predetermined reference value and iii) providing a good prognosis when the expression level is lower than the predetermined reference value and a poor prognosis when the expression level is higher than the predetermined reference value. The invention also relates a compound which is a DNMT3A/ISGF3? antagonist or a compound which is a DNMT3A/ISGF3? gene expression inhibitor for use in the treatment and prevention of cancer.Type: GrantFiled: March 1, 2016Date of Patent: June 30, 2020Assignees: INSERM (INSITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE NANTES, UNIVERSITE D'ANGERS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Pierre-Francois Cartron, Mathilde Cheray, Francois Valette
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Patent number: 10700254Abstract: Disclosed is a thermoelectric cell having thermoelectric tracks of alternating conductivity types connected in series by metallic connections, including a platform suspended over a substrate by arms, the platform and the arms being parts of the same thermally and electrically insulating layer, and each arm supporting a thermoelectric track.Type: GrantFiled: February 13, 2017Date of Patent: June 30, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Olivier Bourgeois, Dimitri Tainoff, Daniel Bourgault
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Publication number: 20200203556Abstract: The invention relates to a method of manufacturing at least one optoelectronic structure on a support substrate. In particular, this invention relates to manufacturing of an optoelectronic structure that has a plurality of coplanar light emitting diodes, and formed from a succession of light emitting stacks. Therefore this invention uses a cavity, the bottom of which has a staged profile, such that the formation of the succession of light emitting stacks reproduces the staged profile of the bottom of the cavity, on its exposed face. Performance of a step to level the succession of light emitting stacks relative to a reference level defined by the exposed surface portion vertically in line with the deepest step, then makes it possible to reveal a set of coplanar light emitting diodes.Type: ApplicationFiled: December 16, 2019Publication date: June 25, 2020Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Guy FEUILLET, Benjamin DAMILANO, Jean-Yves DUBOZ, Christophe LARGERON
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Patent number: 10689298Abstract: A composite material part includes fiber reinforcement made of carbon or ceramic yarns and a matrix that is mostly ceramic, the part further including a first interphase layer covering the yarns and present between the yarns and the matrix, the first interphase layer being a layer of boron nitride doped with aluminum and presenting an atom content of aluminum lying in the range 5% to 15%.Type: GrantFiled: November 22, 2017Date of Patent: June 23, 2020Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Emilien Buet, Paul Carminati, Sylvain Lucien Jacques, Francis Rebillat
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Publication number: 20200188533Abstract: A nucleic acid for the controlled expression of a nucleic acid encoding a pro-apoptotic protein in an individual, including: a regulatory polynucleotide including a minimal promoter and at least one AARE (amino acid response element) nucleic acid, the regulatory polynucleotide being activated in an individual upon consumption of a diet deficient in at least one essential amino acid; and a nucleic acid encoding a pro-apoptotic protein, which is placed under the control of the regulatory polynucleotide.Type: ApplicationFiled: December 26, 2019Publication date: June 18, 2020Applicants: INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventor: Pierre FAFOURNOUX
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Publication number: 20200194259Abstract: A substrate is provided with a monocrystalline silicon-germanium layer with a first surface covered by a protective oxide obtained by wet process and having a degradation temperature. The protective oxide is transformed into fluorinated salt which is then eliminated. The substrate is placed in a processing chamber at a lower temperature than the degradation temperature and is subjected to a temperature ramp up to a higher temperature than the degradation temperature. The first surface is annealed in a hydrogen atmosphere devoid of silicon, germanium and precursors of the materials forming the target layer. When the temperature ramp is applied, a silicon precursor is inserted in the processing chamber between a loading temperature and the degradation temperature to deposit a monocrystalline buffer layer. A mono-crystalline target layer is deposited by chemical vapour deposition.Type: ApplicationFiled: December 17, 2019Publication date: June 18, 2020Applicants: COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITÉ GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Pierre-Edouard RAYNAL, Pascal BESSON, Jean-Michel HARTMANN, Virginie LOUP, Laurent VALLIER
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Patent number: 10684113Abstract: An optical detection device includes a light source emitting a light beam whose electromagnetic field, a means adapted to divide the beam into a first beam defining a first reference pathway and a second beam defining a second sample pathway, a modulation system frequency-shifting the electromagnetic fields of the two beams, a beam coupler adapted to collect the beams, an optical detection system adapted to detect the signal arising from the interference between the beams and coupled via the coupler, the sample being placed in the sample pathway, the optical detection system comprising an optical detector and a device adapted to measure the amplitude and the phase of the signal, an opaque screen comprising an optical aperture is placed at the level of a zone of a sample, in proximity to the sample, in the sample pathway.Type: GrantFiled: January 6, 2017Date of Patent: June 16, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Yannick De Wilde, Lèo Greusard, Gilles Tessier, Sylvain Gigan, Samuel Gresillon, Kamel Bencheikh
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Patent number: 10684190Abstract: A device measures at least a first physical quantity of fluid flow in a three-dimensional space having at least one predetermined interface, between at least two media. The device comprises a computer prescribing first and second conditions at the different boundaries concerning the first physical quantity, associated respectively with a first source and a second source, different to one another, the first and second sources being point sources of mass flow of fluid and/or of force. The computer calculates, by distributed point source calculation, a first value of the first physical quantity from the first condition and from the first source and a second value of the first physical quantity from the second condition and from the second source, at at least one second point, different from the first test point, then combines the values to calculate for the first physical quantity respectively from the different boundary conditions and sources.Type: GrantFiled: May 22, 2015Date of Patent: June 16, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE DE CACHANInventors: Dominique Placko, Alain Rivollet, Thierry Bore
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Patent number: 10682630Abstract: The invention relates to a composition that contains a first semiconductor SC1, particles that comprise one or more element(s) M in the metal state selected from among an element of groups IVB, VB, VIB, VIIB, VIIIB, IB, IIB, IIIA, IVA and VA of the periodic table, and a second semiconductor SC2 that comprises cerium oxide, with said first semiconductor SC1 being in direct contact with said particles that comprise one or more element(s) M in the metal state, with said particles being in direct contact with said second semiconductor SC2 that comprises cerium oxide in such a way that the second semiconductor SC2 covers at least 50% of the surfaces of the particles that comprise one or more element(s) M in the metal state. The invention also relates to its preparation method as well as its application of photocatalysis.Type: GrantFiled: October 6, 2015Date of Patent: June 16, 2020Assignees: IFP ENERGIES NOUVELLES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD—LYON 1Inventors: Dina Lofficial, Antoine Fecant, Denis Uzio, Eric Puzenat, Christophe Geantet
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Patent number: 10682633Abstract: Some embodiments are directed to a new methodology aimed at preparing highly N-doped mesoporous carbon macroscopic composites, and their use as highly efficient heterogeneous metal-free catalysts in a number of industrially relevant catalytic transformations.Type: GrantFiled: January 21, 2016Date of Patent: June 16, 2020Assignees: UNIVERSITÉDE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CONSIGLIO NAZIONALE DELLE RICERCHEInventors: Cuong Pham-Huu, Giuliano Giambastiani, Yuefeng Liu, Housseinou Ba, Lam Nguyen-Dinh, Jean-Mario Nhut, Cuong Duong-Viet
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Patent number: 10683284Abstract: The manufacture and use of compounds of formula (Ia) or a pharmaceutically acceptable salt thereof for preventing, inhibiting or treating cancer, AIDS and/or premature aging. The compounds of formula (Ia) being: where: R independently represents a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —CN group, a hydroxyl group, a —COOR1 group, a (C1-C3)fluoroalkyl group, a —NO2 group, a —NR1R2 group, or a (C1-C3)alkoxy group; R? is a hydrogen atom, a halogen atom, a (C1-C3)alkyl group, a —NO2 group, a (C1-C3)alkoxy group, or a —NR1R2 group; and R1 and R2 are a hydrogen atom or a (C1-C3) alkyl group.Type: GrantFiled: July 31, 2018Date of Patent: June 16, 2020Assignees: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, INSTITUT CURIE, UNIVERSITE DE MONTPELLIERInventors: Jamal Tazi, Florence Mahuteau, Romain Najman, Didier Scherrer, Julien Santo
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Publication number: 20200181618Abstract: RNA aptamers are disclosed with distinct fluorescent properties, fluorophore binding affinities, and salt dependence. Also disclosed are corresponding fluorophores, with selected fluorophores evidencing high cellular permeability. The aptamer's high fluorophore affinities, the high brightness of the bound complexes, and their thermal and salt stability, provide distinct aspects of the disclosed aptamers.Type: ApplicationFiled: April 23, 2018Publication date: June 11, 2020Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE STRASBOURG, SIMON FRASER UNIVERSITY, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICInventors: Michael Ryckelynck, Alexis Autour, Peter Unrau, Elena Dolgosheina, Sunny Chiu Yuk Jeng, Shanker Shyam Sundhar Panchapakesan, Amir Abdolahzadeh, Razvan Cojocaru, Adrian Ferré D'Amaré, Robert Trachman