Patents Assigned to SCIENTIFIQUE (CNRS)
  • Publication number: 20200181041
    Abstract: The disclosure relates to a process for the dimerization of conjugated diene compounds by a heterogeneous catalytic process using a supported palladium catalyst in the presence of at least one palladium activator and at least one palladium coordinating agent.
    Type: Application
    Filed: July 10, 2017
    Publication date: June 11, 2020
    Applicants: TOTAL RAFFINAGE CHIMIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON, ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYON
    Inventors: Mostafa TAOUFIK, Kai Chung SZETO, Cesar RIOS NEYRA, Stéphans KRESSMAN
  • Patent number: 10676791
    Abstract: The present invention relates to a method of testing whether a patient suffering from arge B-cell lymphoma will respond or not to a DNA repair pathway inhibitor comprising: i) determining the expression level (ELi) of several genes Gi-Gn selected from table A in a biological sample obtained from said patient comparing the expression level (ELi) determined at step i) with a predetermined reference level (ELRi) iii) calculating the DNA repair score trough the following formula (I), wherein ?i represent the regression ? coefficient reference value for the gene Gi and Ci=1 if the expression of the gene Gi (ELi) is higher than the predetermined reference level (ELRi) or Ci=?1 if the expression of the gene (ELi) is lower than or equal to the predetermined reference level (ELRi) iv) comparing the score DNARS determined at step iii) with a predetermined reference value DNARSR v) and concluding that the patient will respond to the treatment when the DNARS score is higher than the predetermined reference value DNARSg o
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: June 9, 2020
    Assignees: INSERM(INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE MONTPELLIER, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Jerome Moreaux, Guillaume Cartron, Caroline Bret, Angelos Constantinou, Philippe Pasero
  • Patent number: 10675357
    Abstract: The present invention relates to antibodies having specificity to nectin-4 and uses thereof.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: June 9, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, UNIVERSITÉ D'AIX MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT JEAN PAOLI & IRENE CALMETTES
    Inventors: Marc Lopez, Daniel Olive
  • Patent number: 10680241
    Abstract: The present application describes a process for the preparation of titanium-based compounds having an anatase type structure with cationic vacancies arising from a partial substitution of oxygen atoms by fluorine atoms and hydroxyl groups. Electrochemically active materials comprising the titanium-based compounds for use in lithium-ion battery electrodes are also described.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: June 9, 2020
    Assignees: HYDRO-QUEBEC, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Damien Dambournet, Wei Li, Henri Groult, Sandrine Leclerc, Christian Julien, Karim Zaghib
  • Patent number: 10678970
    Abstract: The invention is a method for exploitation of a sedimentary basin containing hydrocarbons, including optimized scaling of the geological model. Based on categorical property measurements, a first meshed representation of a formation is constructed reflecting the categorical property measurements. At least one second meshed representation having a lower resolution is constructed by assigning a categorical property value to each mesh of the second representation corresponding to a group of meshes of the first representation and storing parameters for changing from the second representation to the first representation with those change parameters enabling reconstitution of the first representation.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: June 9, 2020
    Assignees: IFP ENERGIES NOUVELLES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NICE
    Inventors: Marc Antonini, Frédéric Payan, Sebastien Schneider, Laurent Duval, Jean-Luc Peyrot
  • Publication number: 20200173859
    Abstract: An optically transparent electromagnetic shield assembly comprising an electrical connection device with variable electrical resistance. The electrical connection device electrically connects a conductive two-dimensional structure, which covers a transparent substrate, to a shell portion which is electrically conductive. The resistance of the connection device can be adjusted, either initially for a detection system for which the shield assembly is intended or in real time while the shield assembly is in use, according to an RF radiation intensity.
    Type: Application
    Filed: May 15, 2018
    Publication date: June 4, 2020
    Applicants: SAFRAN ELECTRONICS & DEFENSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITE DE RENNES 1
    Inventors: Cyril Dupeyrat, Patrice Foutrel, Philippe Besnier, Xavier Castel, Yonathan Corredores
  • Publication number: 20200172660
    Abstract: 1) Hydrocarbon copolymer P comprising 2 alkoxysilane end groups F1 and F2 of formulae: —F1: (R?O)3-tRtSi—(CH2)g1- and F2: —(CH2)d1—SiRt(OR?)3-t; or F1: (R?O)3-tRtSi—R?—O(O)C—(CH2)g2— and F2: —(CH2)d2—C(O)O—R?—SiRt(OR?)3-t; wherein t is 0, 1 or 2; g1 and d1 are 1, 2 or 3; g2 and d2 are 0, 1, 2 or 3; R et R? represent a C1-C4 alkyl; R? is a C1-C4 alkylene radical; the main chain comprising motifs (I) and (II) in which R0 is in particular the methyl radical; and the number average molecular mass Mn thereof being between 400 and 100,000 g/mol. 2) Method for producing said copolymer, comprising: (i) a step of heating a statistical bipolymer A selected from a poly(butadiene-isoprene), a poly(butadiene-myrcene) and a poly(butadiene-farnesene); and subsequently (ii) a step of heating the formed product, in the presence of a chain transfer agent of formula (C). 3) Adhesive composition comprising said copolymer.
    Type: Application
    Filed: May 22, 2018
    Publication date: June 4, 2020
    Applicants: BOSTIK SA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE RENNES 1
    Inventors: Guillaume MICHAUD, Xiaolu MICHEL, Frederic SIMON, Stephane FOUQUAY, Sophie GUILLAUME, Jean-Francois CARPENTIER
  • Publication number: 20200171204
    Abstract: The application pertains to the field of biomaterials and their use, in particular for the production of implants to support the growth and recovery of biological tissues. More particularly, a fibrous polymer material is described comprising a first layer of aligned fibroin fiber, a second layer of fibroin fibers, wherein the fibroin fibers are randomly oriented within said second layer, a third layer of aligned fibroin fibers; and polymer scaffolds comprising thereof.
    Type: Application
    Filed: July 12, 2018
    Publication date: June 4, 2020
    Applicants: UNIVERSITE DE TECHNOLOGIE DE COMPIEGNE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE STRASBOURG, UNIVERSITE DE PICARDIE JULES VERNE, CENTRE HOSPITALIER UNIVERSITAIRE AMIENS - PICARDIE
    Inventors: Bernard Devauchelle, Anne Hebraud, Guy Schlatter, Kayla Belanger, Christophe Egles
  • Publication number: 20200171499
    Abstract: A microfluidic device for performing physical, chemical or biological treatment to at least one packet without contamination.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 4, 2020
    Applicants: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Louis VIOVY, Max CHABERT, Kevin DORFMAN
  • Publication number: 20200172800
    Abstract: The present invention concerns a luminescent particle comprising a nanoparticle of formula A1?xLnxVO4(1?y)(PO4)y ??(I) in which A is selected from yttrium (Y), gadolinium (Gd), lanthanum (La), and mixtures thereof; Ln is selected from europium (Eu), dysprosium (Dy), samarium (Sm), neodymium (Nd), erbium (Er), ytterbium (Yb), and mixtures thereof; 0<x<1; and 0<y<1; characterized in that the nanoparticle on its surface has tetraalkylammonium cations in an amount such that said nanoparticle has a zeta potential, ?, of less than or equal to ?28 mV in an aqueous medium with a pH?5, more particularly with a pH?5.5, and with an ionic conductivity >100 ?S.cm?1. It also concerns a method for preparing such luminescent particles, a colloidal suspension of these particles, and the use thereof as a diagnostic agent, and also a diagnostic kit comprising such luminescent particles.
    Type: Application
    Filed: May 18, 2018
    Publication date: June 4, 2020
    Applicants: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Thierry GACOIN, Maximilian RICHLY, Pascal PREIRA, Antigoni ALEXANDROU, Cédric BOUZIGUES, Rabei MOHAMMEDI
  • Publication number: 20200172525
    Abstract: The present disclosure is generally directed to the manufacture and use of compounds described herein for preventing, inhibiting or treating cancer, AIDS and/or premature aging, or the manufacture and use of a pharmaceutical composition comprising at least one of the compounds, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier for preventing, inhibiting or treating cancer, AIDS and/or premature aging.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 4, 2020
    Applicants: ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
    Inventors: Jamal TAZI, Florence MAHUTEAU, Romain NAJMAN, Didier SCHERRER, Julien SANTO
  • Publication number: 20200172967
    Abstract: An object is to provide a component for molecular Computing and a method of molecular Computing. A component for molecular Computing, the component comprising: a microsphere including pores, at least some of which are open on a surface of the microsphere, and a plurality of modules grafted on the microsphere wherein each of the modules is a continuous sequence of nucleic acid base.
    Type: Application
    Filed: February 16, 2016
    Publication date: June 4, 2020
    Applicants: THE UNIVERSITY OF TOKYO, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Guillaume GINES, Yannick RONDELEZ, Teruo FUJII
  • Patent number: 10668129
    Abstract: The present invention relates to the synergistic combination of the short and long Rod-Derived Cone Viability Factors and to methods for treating retinal degenerative diseases.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: June 2, 2020
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Thierry Leveillard, John Flannery, Xin Mei, Leah Byrne, José-Alain Sahel, Emmanuelle Clerin-Lachapelle, Junwei Sun, Jean Bennett, Jeannette Bennicelli
  • Patent number: 10669288
    Abstract: The present invention relates to a complex comprising at least one lanthanide (Ln) and at least one compound (C) comprising a unit of formula (I) below: said unit of formula (I) being covalently connected to at least one antenna which absorbs at a wavelength ranging from 500 nm to 900 nm.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: June 2, 2020
    Assignees: UNIVERSITE D'ORLEANS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Svetlana Eliseeva, Franck Suzenet, Sylvain Routier, Raja Ben Othman, Alexandra Collet, Ivana Martinic, Régis Delatouche, Stéphane Petoud
  • Patent number: 10673538
    Abstract: The disclosure relates to a method for transmitting an item of information in a communication channel linking a transmitter to a recipient, the method including the following successive steps: the determination, by the transmitter, of a first intelligible sound signal representative of the item of information to be transmitted, the acoustic processing, by the transmitter, of the first sound signal so as to produce a second sound signal unintelligible to the recipient, the transmission of the second sound signal from the transmitter to the recipient, the transmission of the first sound signal from the transmitter to the recipient, the transmission of the first sound signal being triggered by the transmission of the second sound signal, the second transmission of the second sound signal from the transmitter to the recipient, the second transmission of the second sound signal being triggered by the transmission of the first signal.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: June 2, 2020
    Assignees: URGO RECHERCHE INNOVATION ET DEVELOPPEMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE NORMALE SUPERIEURE, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, UNIVERSITE PARIS DIDEROT—PARIS 7
    Inventors: Daniel Pressnitzer, Laure Cornu, Hervé Le Lous
  • Patent number: 10672138
    Abstract: Some embodiments are related to a system for estimating a harvest volume in a vineyard operation organized into rows of vine stocks, including: a photographic device for capturing a photographic image of a set of stocks when the system passes between two rows of the vineyard operation; a device for measuring a distance between the vine stocks and the photographic device; and a calculator for detecting the berries within the photographic image, determining a number of berries in a bunch, determining a number of bunches on a stock, and determining an indicator of the volume depending on the number of berries in a bunch, the number of bunches on a stock and the diameter of the berries determined from the photographic image and the distance measurement.
    Type: Grant
    Filed: May 30, 2016
    Date of Patent: June 2, 2020
    Assignees: UNIVERSITÉ DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, É COLE NATIONALE SUPERIÉ URE DES SCIENCES AGRONONOMIQUES DE BORDEAUX (BORDEAUX SCIENCES AGRO)
    Inventors: Christian Germain, Barna Keresztes, Gilbert Grenier, Olivier Lavialle, Jean-Pierre Da Costa
  • Patent number: 10671872
    Abstract: The invention concerns a method for detecting a surgical tool on a first image comprising the following steps: storing shape parameters of the surgical tool; determining a second image (I3) containing distinct pixel regions from the first image by means of a first processing operation comprising the segmentation of the first image; determining first windows (F), each first window surrounding one of the regions; selecting at least one second window from among the first windows, from the shape parameters; determining a third image from the first image by applying, to the first image, a second processing operation implementing Frangi's algorithm; and determining lateral edges of the surgical tool on the part of the third image contained in said second window.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: June 2, 2020
    Assignees: UNIVERSITE GRENOBLE ALPES, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, CEN'TRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Sandrine Voros, Anthony Agustinos, Arnold Fertin
  • Patent number: 10669530
    Abstract: The present invention relates to a new strain of Clostridium acetobutylicum modified to be unable to produce hydrogen and its use for the continuous production of bulk chemicals such as lactate, 1,3-propanediol, ethanol, butanol, isobutanol, 1,3-butanediol, acetate, acetone, isopropanol, 3-hydroxy-3-methylbutyrate and isobutene at high yield.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: June 2, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, INSTITUT NATIONAL DE A RECHERCHE AGRONOMIQUE
    Inventors: Philippe Soucaille, Ngoc-Phuong-Thao Nguyen, Benjamin Percheron, Christian Croux, Isabelle Meynial-Salles
  • Publication number: 20200163916
    Abstract: Probenecid or a pharmaceutical acceptable salt thereof for use in the treatment of a neurological disorder in a subject in need thereof, wherein administration of probenecid or a pharmaceutical acceptable salt thereof controls clinical or electrographic seizures in the subject. Preferably, the neurological disorder is an epileptic disease, disorder or condition.
    Type: Application
    Filed: July 13, 2018
    Publication date: May 28, 2020
    Applicants: PARIS SCIENCES ET LETTRES - QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), SORBONNE UNIVERSITÉ, APHP (ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS), COMMISSARIAT À L'ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES (CEA), UNIVERSITE DE PARIS
    Inventors: Nathalie ROUACH, Eléna DOSSI, Gilles HUBERFELD
  • Patent number: 10662445
    Abstract: An efficient, rapid ex-situ detoxification has been developed to reduce inhibitor concentration and enhance acetone-butanol-ethanol (ABE) production from brewery industry liquid waste (BLW) and brewery spent grain (BSG). About 80±2.0% extraction of furan derivative and more than 95±2.0% extraction of phenolic compounds and almost no extraction of reducing sugar from simulated synthetic media as well as real waste hydrolysate have been obtained. Ex-situ extraction of microbial inhibitors from BLW and BSG hydrolysates using bis-(2-ethylhexyl) sebacate as solvent leads to high production of ABE of 12.67 g/L and 11.23 g/L respectively. Lower power consumption (0.081 W/L) and reuse of the extracting solvent made this detoxification technique extremely useful for improving production of bio-butanol from agro-industrial waste.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: May 26, 2020
    Assignees: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE DE RECHERCHE INDUSTRIELLE DU QUEBEC
    Inventors: Sampa Maiti, Satinder Kaur Brar, Yann LeBihan, Gorka Gallastegui Ruiz de Gordoa