Patents Assigned to SCIENTIFIQUE (CNRS)
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Publication number: 20200308409Abstract: Bitumen that is solid at ambient temperature in the form of granules that include a core made of a first bituminous material and a coating made of a second bituminous material, the second bituminous material having a total content of asphaltenes, extracted using n-alkane, of 30% to 50% by weight in relation to the total weight of the bitumen in the coating.Type: ApplicationFiled: May 22, 2017Publication date: October 1, 2020Applicants: TOTAL MARKETING SERVICES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Mouhamad MOUAZEN, Manuel MERCE, Véronique SCHMITT, Rénal BACKOV
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Patent number: 10788497Abstract: A method which can be used to analyse oxidising species in a sample, including: placing the sample in contact with a first photoluminescent agent, and a second optically active agent, at least the first photoluminescent agent including nanoparticles doped with rare earth elements and being oxidisable, the luminescence of the first photoluminescent agent varying, at least at one first wavelength, with the amount of oxidising species, and the signal emitted by the second optically active agent being constant or varying, at least at one second wavelength other than the first wavelength, with the amount of oxidising species in a direction opposite to the luminescence of the first photoluminescent agent; energising the first and second agents in the sample; measuring the light intensity of the sample at least at the first and second wavelengths; and assessing the presence and/or the amount of oxidising species by interpreting the measured light intensities.Type: GrantFiled: July 28, 2016Date of Patent: September 29, 2020Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Cédric Bouzigues, Mouna Abdesselem, Antigoni Alexandrou, Thierry Gacoin, Jean-Pierre Boilot
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Patent number: 10790634Abstract: A laser system with optical feedback, includes an optical-feedback-sensitive laser which emits, via an output optical fibre, a continuous, frequency-adjustable, propagating, source optical wave, known as the source wave; a resonant optical cavity coupled by means of optical feedback to the laser and configured to generate an intra-cavity wave, one fraction of which returns to the laser in the form of a counter-propagating optical wave; an electro-optic fibre modulator placed on the optical path between the laser and the resonant optical cavity, the electro-optic modulator being configured to generate a phase-shifted source wave by phase-shifting the source wave and, by phase-shifting the counter-propagating optical wave, to generate a phase-shifted counter-propagating wave, known as the feedback wave, which reaches the laser; a phase-control device for generating a control signal for the electro-optic modulator from an error signal representative of the relative phase between the source wave and the feedbackType: GrantFiled: September 27, 2017Date of Patent: September 29, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventor: Samir Kassi
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Patent number: 10787493Abstract: The present invention relates to a modified cytokine of the TNF superfamily, with reduced activity to its receptor, wherein said modified cytokine is specifically delivered to target cells. Preferably, said modified cytokine is a single chain variant of the TNF superfamily, even more preferably, one or more of the chains can-y one or more mutations, resulting in a low affinity to the receptor, wherein said mutant cytokine is specifically delivered to target cells. The targeting is realized by fusion of the modified cytokine of the TNF superfamily to a targeting moiety, preferably an antibody or antibody-like molecule. The invention relates further to the use of such targeted modified cytokine of the TNF superfamily to treat diseases.Type: GrantFiled: June 14, 2019Date of Patent: September 29, 2020Assignees: VIB VZW, UNIVERSITEIT GENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITË DE MONTPELLIER, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE MONTPELLIERInventors: Jan Tavernier, Jennyfer Bultinck, Frank Peelman, Gilles Uze
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Patent number: 10788549Abstract: An antenna array includes a plurality of linear electromagnetic resonators having longitudinal axes oriented parallel to one another and not aligned, and at least one decoupling device arranged between two the linear electromagnetic resonators, wherein the decoupling device comprises a plurality of open-loop electromagnetic resonators that are matched to a frequency located in the bandwidth of the two the adjacent linear electromagnetic resonators, that are electrically insulated and that are arranged in a plurality of planes that are not parallel to a plane containing the longitudinal axes of the two the linear electromagnetic resonators. Nuclear magnetic resonance imaging apparatus comprising such an antenna array is also provided.Type: GrantFiled: January 5, 2017Date of Patent: September 29, 2020Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLEInventors: Elodie Georget, Michel Luong, Alexandre Vignaud, Eric Giacomini, Edouard Chazel, Redha Abdeddaim, Stefan Enoch, Gérard Tayeb
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Patent number: 10787505Abstract: The present invention relates to an oligopeptide and conjugates thereof. The present invention also relates to the use of these oligopeptide conjugates for treating or diagnosing disorders mediated by amyloid ? deposits. Finally, the present invention also relates to a coupling method for obtaining oligopeptide coupled with a substance of interest (functional conjugates).Type: GrantFiled: November 13, 2014Date of Patent: September 29, 2020Assignees: F. HOFFMANN-LA ROCHE AG, INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Pierre Lafaye, Sylvie Bay, Benoit Delatour, Marc Dhenain, Charles Duyckaerts, Tengfei Li, Matthias Vandesquille, Christian Czech, Fiona Grueninger
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Publication number: 20200299653Abstract: The disclosure pertains to the field of molecular means capable of binding to, and preferably of chelating, cGMP, appropriate for use in vitro or in vivo and preferably capable of targeting specific cellular compartments. The polypeptides of the disclosure comprise a chimeric construction derived from the N terminus part of PKG-I? and PKG-I?, and the two cGMP binding sites of the wild type PKG.Type: ApplicationFiled: November 2, 2018Publication date: September 24, 2020Applicants: SORBONNE UNIVERSITÉ, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)Inventors: Xavier Nicol, Oriol Ros Torres
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Publication number: 20200300100Abstract: A turbine component such as a turbine blade or a vane of a distributor, which includes a polycrystalline substrate containing grains, the substrate having at least one Ti3AlC2 phase and the mass fraction of the phase of the alloy is greater than 97%, with the average length of the grains is less than 50 ?m, the average width-to-length ratio is between 0.4 and 0.6, and the average mesh volume of the Ti3AlC2 phase is less than 152.4 ?3.Type: ApplicationFiled: September 21, 2018Publication date: September 24, 2020Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), SAFRANInventors: Pierre SALLOT, Veronique BRUNET, Jonathan CORMIER, Elodie Marthe Bernadette DROUELLE, Sylvain Pierre DUBOIS, Patrick VILLECHAIS
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Patent number: 10780435Abstract: Disclosed is a minifluidic device including a matrix, an elongated guiding duct embedded at least in part in the matrix, with at least one port to the outside of the matrix, a movable fiber at least partly contained in the guiding duct, and able to undergo within the guiding duct, and at least along some part of the fiber, at least one action selected among a sliding, or a deformation, or a rotation and at least one of the movable fiber or the guiding duct is elastic or is non linear along at least part of its length, or at least part of the matrix is elastic.Type: GrantFiled: July 22, 2016Date of Patent: September 22, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE PIERRE ET MARIE CURIEInventors: Bastien Venzac, Ayako Yamada, Jean-Louis Viovy, Stephanie Descroix, Laurent Malaquin
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Patent number: 10781457Abstract: The disclosure relates to a method for increasing the resistance of a plant to a plant RNA virus, comprising expressing in said plant a mutant protein-only RNase P enzyme lacking a nuclear localization signal domain or an organelle targeting sequence domain, and related compositions.Type: GrantFiled: May 22, 2015Date of Patent: September 22, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Philippe Giege, Anthony Gobert
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Patent number: 10783108Abstract: The present invention provides a mechanism whereby active servers are able to extend their RAM by using memory available in standby servers. This can be achieved, without having to take the servers out of their standby mode, by implementing a memory manager operating in at least one active server and configured to directly access the memory of the servers in standby mode, without requiring the processor of these servers in standby mode to be active. In these servers in standby mode, at least their memory, their network card and their communication means are active, whereas at least their processor is in standby mode.Type: GrantFiled: March 6, 2017Date of Patent: September 22, 2020Assignees: INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Daniel Hagimont, Alain Tchana
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Patent number: 10779769Abstract: There is described a method for evaluating a level of noise in a biosignal, the method comprising: receiving a time signal representative of a biological activity, the time signal comprising a biological activity component and a noise component; determining a modulation spectrum for the time signal, the modulation spectrum representing a signal frequency as a function of a modulation frequency; from the modulation spectrum determining a first amount of modulation energy corresponding to the biological activity component and a second amount of modulation energy corresponding to the noise component determining an indication of the level of noise using the first and second amounts of modulation energy; and outputting the indication of the level of noise.Type: GrantFiled: February 17, 2015Date of Patent: September 22, 2020Assignee: INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Tiago Henrique Falk, Diana Patricia Tobon Vallejo, Martin Maier
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Patent number: 10780331Abstract: Some embodiments are directed to an analysis device for board sports, intended to be secured to a board, such as a surfboard or ski, at the interface with the user. The device includes: a force sensor designed to capture one or more forces generated by the user on the board; a position and motion sensor designed to capture the position, speed and acceleration of the board in space; and a processing unit or processor connected to the force sensor and to the position and motion sensor and designed to synchronize and process the data from the sensors.Type: GrantFiled: June 29, 2016Date of Patent: September 22, 2020Assignees: UNIVERSITÉ DE BOURDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE NATIONAL SUPÉRIEURE D'ARTS ET MÉTIERS (ENSAM), AMVALORInventors: Kévin Lestrade, Jean-Luc Barou, Philippe Viot, Sandra Guérard, Patrick Lanusse
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Publication number: 20200292247Abstract: The present invention concerns a method of refrigerating a housing to a target temperature according to which: an evaporator is placed in said housing; said evaporator is placed in fluid communication with a thermochemical reactor Ri, simultaneously, the heat produced at said reactor Ri is evacuated; Characteristically, at least n>1 other thermochemical reactors are provided; I) the pressure Pevi in said evaporator after it is placed in fluid communication with said thermochemical reactor Ri, and the temperature of said thermochemical reactor Ri connected to said evaporator, are determined; II) when the temperature difference DTRi between the temperature of said reactor Ri connected to said evaporator and the equilibrium temperature TeSi of said reactive mixture contained in said thermochemical reactor Ri at the pressure Pevi of said evaporator is equal to a first predetermined differential and/or when the temperature difference DTev between said evaporator and the interior of said housing is equType: ApplicationFiled: September 7, 2018Publication date: September 17, 2020Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Aleix PUBILL, Laurent RIGAUD, David TADIOTTO, Driss STITOU, Nathalie MAZET
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Publication number: 20200288943Abstract: An optical fibre having a functionalised distal exploration end including a sheath, and a ferrule rigidly connected to the sheath at the distal exploration end, characterised in that the distal exploration end has a functionalised head which is removably attached on the ferrule. Also, a method of assembling the optical fibre.Type: ApplicationFiled: May 15, 2018Publication date: September 17, 2020Applicants: KAMAX INNOVATIVE SYSTEM, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LIMOGESInventors: Jérôme DESROCHES, Olivier BAUDET, Martine LEJEUNE, Romain TRIHAN, Fabrice LALLOUE
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Patent number: 10772930Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.Type: GrantFiled: March 27, 2018Date of Patent: September 15, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), UNIVERSITE DE RENNES 1, UNIVERSITE DE BRETAGNE OCCIDENTALEInventors: Florie Desriac, Yannick Fleury, Patrick Le Chevalier, Delphine Destoumieux, Matthieu Simon
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Patent number: 10775747Abstract: The invention relates to a gas cell for an atomic sensor, comprising an optical cavity provided with at least one optical window (9) and fillable with a gas. The cell also comprises a sealing cup comprising a cavity mouth, a channel mouth, and a sealing access, as well as a membrane which hermetically closes the sealing access of the sealing cup. The membrane can be plastically deformed by heating so as to hermetically close the cavity mouth and/or the channel mouth, in such a way as to hermetically separate the optical cavity from the gas inflow channel.Type: GrantFiled: July 13, 2016Date of Patent: September 15, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE DE FRANCHE COMTEInventors: Vincent Maurice, Nicolas Passilly, Christophe Gorecki
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Patent number: 10774142Abstract: The present invention relates to Anti-Mullerian Hormone (AMH) neutralizing antibodies and their use in the field of reproduction.Type: GrantFiled: September 23, 2016Date of Patent: September 15, 2020Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS DIDEROT—PARIS 7, UNIVERSITE PARIS—SUDInventors: Nathalie Di Clemente-Besse, Nathalie Josso, Richard Cate, Corinne Belville
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Patent number: 10775702Abstract: Disclosed is a lithography process on a sample with at least one emitter, the process including: putting at least one layer of resist above the sample; exciting one selected emitter with light through the at least one layer of resist; detecting light emitted by the excited selected emitter and determining a position of the selected emitter; and curing with a light beam a part of the at least one layer of resist above the position of the selected emitter, the light beam being a shaped light beam having a cross-section, this cross-section having a central part, an intermediate part surrounding the central part and a border part surrounding the intermediate part, the intensity of the shaped light beam on the at least one layer of resist reaching a maximum at the intermediate part.Type: GrantFiled: February 12, 2018Date of Patent: September 15, 2020Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE, UNIVERSITE DE PARISInventors: Agnès Maitre, Amit Raj Dhawan, Pascale Senellart, Cherif Belacel
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Publication number: 20200283344Abstract: A method for preparing polycrystalline fluoride ceramics using powder of fluoride ceramics nanocrystallites as starting material, wherein the method includes: (a) Optionally, a pre-processing step at a temperature ranging from 100° C. to 300° C. at vacuum of 10-5 mbar (10-3 Pa) to 10-8 mbar (10-6 Pa) for 30 minutes to 10 hours, (b) Applying a uniaxial pressure in the range from 1 to 200 MPa, at or around ambient temperature, to obtain a pre-compacted sample, (c) Applying to the pre-compacted of step b) a hydrostatic pressure by Cold Isostatic Pressing, to obtain a pre-compacted sample, (d) Loading the pre-compacted sample from step (c) into a die and submitting the sample to a uniaxial compression in combination with electric field-assisted sintering, under vacuum equal to or higher than 5 Pa. Polycrystalline fluoride ceramics obtained by this method find use in IR devices.Type: ApplicationFiled: February 8, 2017Publication date: September 10, 2020Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Alan LARGETEAU, Mythili PRAKASAM, Inka MANEK-HÖNNINGER