Patents Assigned to Siemens Healthcare Diagnostics Inc.
  • Publication number: 20200200698
    Abstract: In vitro diagnostic sensors are disclosed that include membranes formed of a polymer matrix that has been modified to contain surface adhesion functional group(s) that enables attachment of the membrane to a substrate of the sensor. Also disclosed are membranes of these sensors as well as multi-sensor arrays that include multiple sensors. In addition, methods of producing and using these membranes, sensors, and arrays are disclosed.
    Type: Application
    Filed: September 13, 2018
    Publication date: June 25, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: John Benco
  • Publication number: 20200200730
    Abstract: A method and a device for determining the concentration of an analyte in whole blood is disclosed. In one embodiment, the method includes generating a plasma layer in the whole blood sample. Furthermore, the method includes exposing the plasma layer to light. The method also includes capturing light reflected from the plasma layer. Additionally, the method includes analyzing the reflected light to determine the concentration of the analyte.
    Type: Application
    Filed: June 7, 2018
    Publication date: June 25, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Satish Kumar Dubey, Ashish Kumar Lal, Vishal Manjanath Prabhu, David Ledden
  • Publication number: 20200197923
    Abstract: Devices, kits, and methods related to embodiments of an improved liquid test sample injection device for use in diagnostic assays and for the collection of liquid waste produced from such diagnostic assays.
    Type: Application
    Filed: September 13, 2018
    Publication date: June 25, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Aman Ullah
  • Patent number: 10690597
    Abstract: The timing of the reaction of moisture-sensitive reagents for detecting the presence of analytes, e.g. leukocytes in urine samples, is used to detect when the reagents have been compromised by excess humidity. The ratio of light reflectance at wavelengths characteristic of the products of reaction between the reagents and the analyte and an infra-red reference dye is measured at two preset times after a urine sample has been applied to a test strip and used to determine whether the reagents have been compromised by excessive humidity. The presence of unusually dark samples is determined from the reflected light at 470 and 625 nm in order to confirm that the test strips are humidity-compromised.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: June 23, 2020
    Assignee: Siemens Healthcare diagnostics Inc.
    Inventors: Chris T. Zimmerle, Michael J. Pugia
  • Patent number: 10690608
    Abstract: A sensor assembly has a substrate with a first surface and a second surface opposite the first surface, at least one analyte sensor positioned on at least one of the first surface and the second surface of the substrate, and at least one electrical contact positioned on the substrate in electrical communication with a corresponding one of the at least one analyte sensor. The substrate is configured to define a tube having an interior surface, and an exterior surface. At least a portion of the first surface of the substrate defines the interior surface of the tube, and the at least one analyte sensor is disposed on at least one of the interior surface and the exterior surface of the tube.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: June 23, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Jennifer A. Samproni, Jeffrey R. Jasperse
  • Publication number: 20200188906
    Abstract: The invention relates to a container for a rack of a diagnostic robot comprising: —a container body comprising a sidewall or multiple sidewalls, a bottom and a top wherein the container body is of round, oval, square, rectangular, hexagonal or polygonal cross sectional shape, —the top is provided with an opening that matches the size and form of a filter membrane/supporting body of an object carrier which is placed over the opening in the top of the container for filtration of a sample, wherein the opening exhibits a rim and —the top is provided with a top-guiding-means which matches with a corresponding object-carrier-guiding-means on or in the object carrier so that the object carrier locks with a predetermined surface faced up into a predetermined position on the top and —the container is equipped with an adapter which matches a gas outlet on the rack.
    Type: Application
    Filed: February 18, 2017
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Claus Tuma
  • Publication number: 20200192465
    Abstract: Disclosed herein is a method of enabling supervision of a laboratory environment utilizing diagnostic equipment. The method includes utilization of a device for capturing an optical image of at least a portion of the laboratory environment. The method further requires selectively capturing the optical image using the image capture device and selectively transmitting the captured image over a communications medium. The method further requires receiving the transmitted optical image by an image receiver in communication with the image transmission device via the communications medium. The method then requires selectively generating, by an image processor in communication with the image receiver, a display of at least a portion of the captured optical image on an image display device and receiving status information from the diagnostic equipment at a laboratory manager that is in communication with multitude of diagnostic equipment.
    Type: Application
    Filed: May 16, 2018
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Sandeep M. Naik
  • Publication number: 20200190037
    Abstract: Hydrophilic, high quantum yield, chemiluminescent acridinium compounds with increased light output, improved stability, fast light emission and decreased non specific binding are disclosed. The chemiluminescent acridinium esters possess hydrophilic, branched, electron-donating functional groups at the C2 and/or C7 positions of the acridinium nucleus.
    Type: Application
    Filed: February 26, 2020
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Anand Natrajan, David Sharpe, Qingping Jiang, David Wen
  • Publication number: 20200188910
    Abstract: The present invention relates to a device comprising a container having an inner wall and at least one opening, containing a mixture containing at least one reagent, and at least one additive, a method of producing this device, and a method of extracting a substance from a sample, enriching a substance in a sample, and/or detecting a substance in a sample using the device.
    Type: Application
    Filed: April 24, 2018
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Walter Gumbrecht, Yiwei Huang, Peter Paulicka
  • Publication number: 20200196115
    Abstract: A location based dynamic information provision system integrates operator positional awareness within a laboratory environment with a laboratory environment asset site map. At least one operator proximity metric, defining a distance threshold for establishing whether an operator within the laboratory is proximate to a respective asset, is defined for each asset. Operator detection and position is provided by an indoor positioning system. A signaling device associated with each operator is in communication with a laboratory process management platform for receiving operator information contingent upon the respective operator being within the proximity metric for a respective laboratory asset and the asset having communicated status of a given urgency to the process management platform. The signaling device may enable the operator to communicate with the process management platform and may provide a tactile or other attention attracting signal to the operator.
    Type: Application
    Filed: May 7, 2018
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Sandeep M. Naik
  • Publication number: 20200191714
    Abstract: A characterization apparatus including pattern generation. The characterization apparatus is configured to characterize a specimen and or a specimen container in some embodiments. The characterization apparatus includes an imaging location configured to receive a specimen container containing a specimen, one or more image capture devices located at one or more viewpoints adjacent to the imaging location, and one or more light panel assemblies including pattern generation capability located adjacent to the imaging location and configured to provide back lighting. Methods of imaging a specimen and/or specimen container using the pattern generation are described herein, as are other aspects.
    Type: Application
    Filed: November 13, 2017
    Publication date: June 18, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Patrick Wissmann, Ludwig Listl, Benjamin S. Pollack
  • Patent number: 10677780
    Abstract: Compositions, kits, and devices that include calibration and/or quality control reagent(s) for monitoring the performance of blood gas, electrolyte, and/or metabolite instrumentation are disclosed. Different oxygen levels in the calibration and/or quality control reagent(s) can be generated using an oxygen scavenger. Methods of accurately measuring the oxygen levels so generated using a by-product of the oxygen scavenger are also disclosed.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: June 9, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Bong Oh
  • Publication number: 20200170551
    Abstract: Compositions, devices, kits, and methods for calibrating at least one oxygen sensor in a blood gas, electrolyte, and/or metabolite instrument utilizing a calibration fluid comprising a pyrogallol oxygen scavenger.
    Type: Application
    Filed: July 2, 2018
    Publication date: June 4, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Kevin Horan, Murli Narayan
  • Publication number: 20200173955
    Abstract: A magnesium sensing membrane is disclosed for use in a potentiometric ion selective electrode that exhibits improved stability upon exposure to surfactant-containing reagents. Kits containing same are disclosed, along with methods of production and use of the magnesium sensing membrane.
    Type: Application
    Filed: February 5, 2020
    Publication date: June 4, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Wei Zhang, Kevin Horan
  • Patent number: 10671833
    Abstract: A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a plurality of DHM images acquired using a digital holographic microscopy system. One or more connected components are identified in each of the plurality of DHM images and one or more training white blood cell images are generated from the one or more connected components. A classifier is trained to identify a plurality of white blood cell types using the one or more training white blood cell images. The classifier may be applied to a new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types. The new white blood cell image and the plurality of probability values may then be presented in a graphical user interface.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: June 2, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Noha El-Zehiry, Shanhui Sun, Bogdan Georgescu, Lance Ladic, Ali Kamen
  • Patent number: 10670614
    Abstract: Aspects of the present invention are directed to devices, systems and methods that enable the quick and reliable detection of hemolysis in a sample such that a sample which exhibits an unacceptable level of hemolysis can be flagged or disregarded in an associated diagnostic test.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: June 2, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Andrew John Baxter, Paul William Cotton
  • Patent number: 10670500
    Abstract: There is provided a system (10) and method (100) for improving ICC and/or ISH rare cell detection by lowering background noise and providing enhanced detection of rare cells (15). In an embodiment, background noise for an ICC and/or an ISH rare cell detection assay is reduced and rare cell signaling is enhanced via feedback control. To accomplish the feedback control, an electronic control circuit (24) can direct a fluid delivery apparatus (18) to add an adjustment amount to account for fluid loss in the system (10) when fluid loss is indicated.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: June 2, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventors: Michael Pugia, Julia Philip, Karen Marfurt
  • Patent number: 10670550
    Abstract: In one illustrative embodiment, a test strip with a first planar substrate has coplanar electrodes on a first planar surface and a second planar substrate (which opposes the first surface of the first planar substrate) has coplanar electrodes on a second planar surface. The first planar surface of the first planar substrate having a first sensing area electrically connected to a first electrical contact. The second planar surface of the second planar substrate having a second electrical contact electrically connected to the first electrical contact via a conductive element, the conductive element extending between the first surface of the first planar substrate and the second surface of the second planar substrate without passing through the first planar substrate, the second planar substrate, or any intermediate layers.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: June 2, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Jennifer A. Samproni
  • Patent number: 10668622
    Abstract: Maintenance carriers can include one or more tools to perform a maintenance operation. These carriers may include removable cartridges that include the tool or consumables, such as a cleaning fluid, compressed gas, or disposable items. Maintenance carriers can also be configured to move along with other carrier traffic in the automation system and may be selectively deployed.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: June 2, 2020
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Benjamin S. Pollack
  • Publication number: 20200169699
    Abstract: A depth-sensitive system for monitoring for and detecting a predefined condition at a specific location within a visually monitored portion of an area. Plural depth-sensitive cameras are oriented with respect to the area whereby each camera has a field of view within the area that at least partially overlaps with the field of view of another of the plural cameras. The combined field of view encompasses all portions of interest of the area. A system for providing a notification of the visual detection of a predefined condition at a particular location or set of locations within an area of interest is provided, as is a system for generating a visual representation of human activity at one or more specific locations within an area of interest.
    Type: Application
    Filed: August 8, 2018
    Publication date: May 28, 2020
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventor: Michael Heydlauf