Patents Assigned to SOOCHOW UNIVERSITY
  • Patent number: 11497722
    Abstract: The present invention provides the use of a metformin salt, particularly metformin monothreonate, in the preparation of a medicament for treating cerebral infarction. The metaformin monothreonate of the present invention has an excellent effect in the treatment of cerebral infarction. The present invention also provides a method for preparing metformin monothreonate and a composition comprising metformin monothreonate.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 15, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Xuechu Zhen, Zongyin Liu, Linyi Qian, Huimin Cao
  • Patent number: 11498984
    Abstract: The invention relates to a method for preparing a vinyl ether polymer by photo-initiated polymerization, which comprises the step of: under a protective atmosphere, performing photo-initiated polymerization on a vinyl ether monomer in the presence of an organic halogenated hydrocarbon and manganese carbonyl under irradiation of light having a wavelength of 365-550 nm at ?25° C. to 25° C., to obtain a vinyl ether polymer after the reaction is completed. In the method, a vinyl ether monomer is subjected to cationic polymerization in the presence of manganese carbonyl and an organic halogenated hydrocarbon under visible light, to prepare a vinyl ether polymer with controlled molecular weight and narrow molecular weight distribution.
    Type: Grant
    Filed: September 25, 2019
    Date of Patent: November 15, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jian Zhu, Xiaofei Huang, Jiajia Li, Na Li, Xiangqiang Pan, Xiulin Zhu
  • Patent number: 11485722
    Abstract: The present invention discloses a cyclopenta[c]chromene compound and a preparation method thereof. A chalcone compound as a reactant, A cationic rare earth metal compound Ln(CH3CN)9]3+[(AlCl4)3]3?.CH3CN as a catalyst, and 2-naphthalenethiol as an accelerator, react in an organic solvent to prepare the cyclopenta[c]-chromene compound. Ln represents a positive trivalent rare earth metal ion, which is selected from the group consisting of La, Nd, Sm, Gd, and Yb. The starting materials are easy obtained, the reaction process is simple, and the yield of the target product is high, up to 85%.
    Type: Grant
    Filed: January 31, 2021
    Date of Patent: November 1, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Fan Xu, Xiaoyou Ding, Dandan Li, Yanan Zhu, Zhigang Yao
  • Patent number: 11484207
    Abstract: The present disclosure provides a method for determining an ultrasound focus location in a thermal image. In one aspect, the method includes obtaining a magnetic resonance thermal image of a tissue heated by a focused ultrasound and correcting a chemical shift and a k-space shift of a monitored ultrasound focus location in the magnetic resonance thermal image such that the monitored ultrasound focus location is aligned with a real physical ultrasound focus location. Correcting the chemical shift includes correcting a first spatial error of the monitored ultrasound focus location caused by resonance frequency changes of hydrogen nuclei due to environmental differences of water molecules. Correcting the k-space shift includes correcting a second spatial error of the monitored ultrasound focus location caused by temperature error due to spatial variations of a primary magnetic field.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: November 1, 2022
    Assignee: Soochow University
    Inventor: Chang-Sheng Mei
  • Patent number: 11479671
    Abstract: This invention provides a scrollable and foldable transparent polysiloxane film and its preparation and self-healing method. 2-Hydroxyethyl disulfide, diisocyanate and alkane chloride were mixed and reacted to get disulfide-containing diisocyanate. ?,?-Aminopropyl terminated polydimethylsiloxane, diisocyanate and alkane chloride were mixed and reacted get linear chain-extended polydimethylsiloxane. Linear chain-extended polydimethylsiloxane, multi-amino terminated hyperbranched polysiloxane, disulfide-containing diisocyanate and alkane chloride were mixed and poured into a mould. After drying, the scrollable and foldable transparent polysiloxane film was obtained. The polysiloxane film described in this invention are constructed by dynamic physical crosslinking induced by hydrogen bond and permanent chemical crosslinking generated by hyperbranched polysiloxane. Hence, the polysiloxane film achieves both high stiffness and toughness.
    Type: Grant
    Filed: July 4, 2018
    Date of Patent: October 25, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Guozheng Liang, Youhao Zhang, Aijuan Gu, Li Yuan
  • Patent number: 11474011
    Abstract: The present invention discloses a bending test apparatus and method for a flexible sheet material. The apparatus comprises a mounting table and further comprises a clamping unit and a bending shaft unit. The clamping unit comprises a clamping part. The bending shaft unit comprises a bending shaft extending in a Z-axis direction. The bending shaft has an arc-shaped sidewall for abutting against a flexible sheet material at an end thereof away from the clamping part. The clamping part moves relative to the bending shaft in a Y-axis direction. The present invention has the following advantage: During a test, a flexible sheet material is bent with a lower external strain, has a wide adjustment curvature range, and the structure is optimized.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: October 18, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Mingxiang Wang, Wei Jiang, Dongli Zhang, Huaisheng Wang, Ming Wu, Nannan Lv
  • Patent number: 11472935
    Abstract: The present invention provides a colored radiative cooler based on a Tamm structure, including a substrate on which metal film and dielectric layers A to G are sequentially provided from bottom to top, where the Tamm structure is formed from the metal film and the dielectric layers A to D; a distributed Bragg reflector is formed from the dielectric layers A to D; and a selective emitter is formed from the dielectric layers E to G. Compared to the conventional radiative cooler, the colored radiative cooler not only has better cooling performance, but it has a wide applications in many aspects such as aesthetics and decoration.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: October 18, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Xiaofeng Li, Chunxiang Sheng, Yidan An, Cheng Zhang, Jun Du, Yan Ye, Linsen Chen
  • Patent number: 11473238
    Abstract: The invention relates to a water-repellent and lipophilic composite needle-punched nonwoven fabric and a preparation method thereof. The method comprises the following steps: blending a PET fiber and a polyolefin-based fiber in a mass ratio of 3:1-1:3, and performing needle punching to obtain a composite needle-punched nonwoven fabric; carrying out hot-drying treatment on the composite needle-punched nonwoven fabric at 110-160° C. for 40-90 min; and carrying out water-repellent finishing on the hot-dried fabric using 50-70 mL/L of an aqueous solution of a modified resin-based fluorine-free waterproofing agent, and drying to obtain the water-repellent and lipophilic composite needle-punched nonwoven fabric, wherein the water-repellent finishing is dip rolling, the air pressure is 1.8 kPa and the liquid carrying rate is 160-230%.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: October 18, 2022
    Assignees: NANTONG TEXTILE AND SILK INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, SOOCHOW UNIVERSITY
    Inventors: Huijing Zhao, Yingmei Zhang
  • Patent number: 11469817
    Abstract: The invention provides a protection method against failure of AI-based QoT prediction, comprising calculating a first number of frequency slots and a consumable margin for a working lightpath that meet the traffic demand according to a method for allocating an OSNR margin for a working lightpath; calculating a second number of frequency slots and a consumable margin for the protection lightpath that meet the traffic demand according to a method for allocating an OSNR margin for the protection lightpath; and evaluating utilization of spectrum resource based on the first number of frequency slots and the second number of frequency slots and evaluating reliability of lightpath based on the consumable margin for the working lightpath. The method of the invention is more stable in practical network applications.
    Type: Grant
    Filed: December 15, 2019
    Date of Patent: October 11, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Gangxiang Shen, Ningning Guo
  • Publication number: 20220313719
    Abstract: A method of treating diseases associated with changes in platelet counts and a method for inhibiting and promoting platelet apoptosis using protein kinase a activator and inhibitor are provided. Protein kinase A regulates platelet apoptosis by means of regulating the phosphorylation of serine at BAD position 155; the activation of protein kinase A activity may inhibit the occurrence of endogenous platelet apoptosis, and may also increase circulating platelet counts in experimental animals; in addition, inhibiting PKA activity may induce platelet apoptosis in vitro, while also reducing circulating platelet counts in the body, indicating that PKA inhibitors may participate in the treatment of thrombocytosis, and reduce platelet counts in peripheral circulating blood.
    Type: Application
    Filed: April 25, 2022
    Publication date: October 6, 2022
    Applicant: Soochow university
    Inventor: Kesheng DAI
  • Patent number: 11452991
    Abstract: The invention aims to provide a copper mesh coated with manganese molybdate and application thereof in the separation of oil-water emulsion and degradation of organic pollutants in water. A large amount of nano-scale manganese molybdates are grown on the surface of a copper mesh through a two-step hydrothermal method. Thereby, a multifunctional composite material is prepared, which can effectively separate oil-water emulsion and degrade organic pollutants in water. The copper mesh has good recyclability. Most of all, the product is suitable for industrial production to achieve the purpose of treating water pollution.
    Type: Grant
    Filed: April 17, 2020
    Date of Patent: September 27, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Dongyun Chen
  • Patent number: 11453086
    Abstract: The present invention relates to a method for laser cladding and forming of a metal or alloy under partial atmosphere protection. Including: transporting a metal or alloy powder beam by an inert carrier gas to move on a machined surface with a focused laser beam; and forming at least one layer of inert protective gas at the outer periphery of the metal or alloy powder beam. The inert protective gas includes first inert protective gas, and the first inert protective gas is at the outer periphery of the focused laser beam. The problems of limited size, high cost and difficulty in moving a cladding and forming system and the like during part forming are solved by forming the inert protective gas at the outer periphery of the focused laser beam. Compared with the prior art, the convenient, fast and economical method is provided for on-site part forming and repair.
    Type: Grant
    Filed: March 12, 2018
    Date of Patent: September 27, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Tuo Shi, Geyan Fu, Shihong Shi, Jizhuo Wu
  • Patent number: 11451890
    Abstract: The invention provides a virtual optical network-oriented spectrum resource trading method and system. The method includes: after virtual optical networks are constructed according to a preset topological structure, in different time slots, controlling, based on capacity demand information of virtual links of the virtual networks, cumulative credit values of the virtual optical networks, and a preset credit threshold, the virtual links between the virtual optical networks to trade spectrum resources of a common physical link, to implement that the virtual optical networks trade spectrum resources according to a real-time capacity demand.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: September 20, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Gangxiang Shen, Shifeng Ding
  • Patent number: 11447625
    Abstract: The present invention relates to the technical field of polymer spectral probes, and particularly to a perchloroethylene derivative and use thereof. The perchloroethylene derivative is prepared by reacting a compound A and a perchloroethylene resin. According to the present invention, the fluorescent polymer can be used as a high-selectivity and high-sensitivity enhanced colorimetric and fluorescent polymer probe for Fe3+ and Cr3+ As compared with the organic small molecule spectral probe, the polymer spectral probe has improved mechanical property, film forming property and excellent recyclability, and thus has a strong practicability.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: September 20, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Dongmei Xu, Wenbo Guo
  • Patent number: 11439990
    Abstract: The invention provides a titanium carbide nanosheet/layered indium sulfide heterojunction and an application of the same in degrading and removing water pollutants. A simple electrostatic self-assembly method is used to uniformly absorb indium ions on the surfaces of Ti3C2 nanosheets, which effectively inhibits the stacking of the nanosheets and is beneficial to the uniform growth of In2S3 nanosheets on the surfaces of the Ti3C2. The present invent overcomes two disadvantages of too fast photogenerated carrier recombination rate of In2S3 and easy agglomeration of nano-scale In2S3, and effectively improves the separation efficiency and photocatalytic activity of photogenerated electron-hole of In2S3.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: September 13, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianmei Lu, Najun Li
  • Patent number: 11442097
    Abstract: The present application discloses a method and apparatus for calculating the kink current of SOI device, which is used to solve the problem that the kink current calculation in the prior art is not accurate and is not suitable for circuit simulation. The method includes: obtaining the impact ionization factor, the parasitic transistor effect factor, and the drain saturation current of the SOI device respectively; and calculating the kink current of the SOI device according to the impact ionization factor, the parasitic transistor effect factor, and the drain saturation current.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: September 13, 2022
    Assignee: Soochow University
    Inventors: Mingxiang Wang, Yanyan Chen, Dongli Zhang, Huaisheng Wang
  • Patent number: 11440924
    Abstract: Disclosed is a method for preparing a borate ester on the basis of a tricyclopentadienyl rare earth metal complex, the method comprising the following steps: uniformly stirring and mixing a catalyst, a borane and a carbonyl compound for reaction to prepare a borate ester, wherein the catalyst is a tricyclopentadienyl rare earth metal complex; and the molecular formula of the tricyclopentadienyl rare earth metal complex can be expressed as: Ln(Cp)3, wherein Ln represents a rare metal selected from one of lanthanide elements. The preparation method has a higher catalytic activity, mild reaction conditions, a product that is easy to post-treat, a short reaction time, a low catalyst consumption amount, and a good range of applicable substrates, and can be used for industrial production.
    Type: Grant
    Filed: April 15, 2017
    Date of Patent: September 13, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Mingqiang Xue, Dandan Yan, Sufang Chen, Qi Shen
  • Patent number: 11420925
    Abstract: Disclosed are a reduction method and reduction product of an alkenyl active methylene compound. The reduction reaction comprises the following steps: taking an alkenyl active methylene compound as a substrate, a metal hydride as a reducing agent, and a palladium compound as a catalyst, performing a reduction reaction to obtain a reduction product, and then reducing the alkenyl active methylene compound. The reduction system is a simple method for reducing the alkenyl active methylene compound, and the used hydride and palladium compound catalyst are both reagents that could easily be obtained in a laboratory. Compared with conventional hydrogen hydrogenation methods and reduction methods of reducing agents, the method is easier to operate, higher in safety, mild in conditions, and high in reaction yield, a reaction in a one-pot two-step manner can be achieved, and high atom economy and step economy can be obtained.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: August 23, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Shilei Zhang, Yujian Mao
  • Patent number: 11420876
    Abstract: A method for preparing a zeolite molecular sieve includes the steps of: (1) mixing at least one of a silicon source, an aluminum source and a phosphorus source with an alkaline substance, a template agent and water uniformly to obtain a zeolite molecular sieve precursor solution; aging the zeolite molecular sieve precursor solution at 20-30° C. for 10-15 h; and subjecting the aged solution to ionizing radiation, and then washing the obtained solid to neutrality and drying to obtain the zeolite molecular sieve. The method of the present invention is green, simple and extremely cost-effective. Under the irradiation of an ionizing radiation source, the synthesis period of zeolite molecular sieve is short and no heating is needed in the preparation process, so energy consumption is reduced and a high-pressure system is avoided.
    Type: Grant
    Filed: January 9, 2020
    Date of Patent: August 23, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Shuao Wang, Mingxing Zhang, Junchang Chen
  • Patent number: 11401288
    Abstract: A method for preparing a ?-amino phosphonic acid derivative includes: dissolving N-(arylvinyl)benzamide, dialkyl phosphite, manganese acetate, and potassium carbonate in a solvent and reacting at room temperature to obtain (2-benzamido-1-arylvinyl)dialkyl-phosphonate derivative; and hydrolyzing (2-benzamido-1-arylethyl)dialkylphosphonate derivative to obtain ?-amino phosphonic acid derivative. The N-(arylvinyl)benzamide derivative is used as starting material. The raw materials are easy to obtain and are of many different types. A method of preparing ?-aminophosphonic acid derivative includes: dissolving N-(arylvinyl)benzamide, dialkyl phosphite, manganese acetate and potassium carbonate in a solvent, reacting at room temperature to obtain (2-benzamide-1-arylvinyl) dialkyl phosphonate derivative, and then reducing and hydrolyzing the compound to obtain ?-aminophosphonic acid derivative.
    Type: Grant
    Filed: January 12, 2021
    Date of Patent: August 2, 2022
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Jianping Zou, Dongliang Zhang, Chengkun Li, Guoyu Zhang, Zekun Tao