Abstract: A method for deep learning video microscopy-based antimicrobial susceptibility testing of a bacterial strain in a sample by acquiring image sequences of individual bacterial cells of the bacterial strain in a subject sample before, during, and after exposure to each antibiotic at different concentrations. The image sequences are compressed into static images while preserving essential phenotypic features. Data representing the static images is input into a pre-trained deep learning (DL) model which generates output data; and antimicrobial susceptibility for the bacterial strain is determined from the output data.
Type:
Application
Filed:
April 5, 2018
Publication date:
May 6, 2021
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Systems and methods for implementing a lightweight checkpoint technique for resilience against soft errors are disclosed. The technique provides effective, safe, and timely soft error detection and recovery using software. In an exemplary aspect, resilience against data flow errors and control flow errors is provided in critical or mixed-critical applications in each basic block or at critical basic blocks. Verified register preservation is provided at each basic block, along with memory preservation checkpoints. In this manner, soft errors are quickly detected and addressed. The register and memory preservation further allows for safe re-execution from recoverable soft errors. Control flow errors can also be detected at the beginning and/or end of each basic block.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
May 4, 2021
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Moslem Didehban, Sai Ram Dheeraj Lokam, Aviral Shrivastava
Abstract: 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD), as well as variants, derivatives, analogs, modifications, and conjugates thereof, are identified as therapeutic agents for treating or preventing human cancers and precancerous conditions. DMDD can be isolated from the root of Averrhoa carambola L., commonly known as starfruit. Pharmaceutical and nutraceutical compositions, as well as dietary supplements, are provided, as are methods of administration and treatment.
Abstract: A plasmonic phase modulator is provided. The modulator has a conductive layer, and a dielectric layer disposed on the conductive layer. A plasmonic layer is disposed on the dielectric layer. A plasmonic layer is disposed on the dielectric layer. The plasmonic layer is conductive to surface plasmon polariton (SPP) waves. The plasmonic layer may be, for example, a graphene sheet. A voltage signal source is operatively connected between the conductive layer and the plasmonic layer for modulating a propagation speed of an SPP wave propagating on the plasmonic layer.
Type:
Grant
Filed:
April 9, 2018
Date of Patent:
May 4, 2021
Assignees:
The Research Foundation for The State University New York, The Research Foundation of CUNY
Abstract: The present disclosure relates to wheat plants having grain with high ?-glucan content, methods for constructing said wheat plants, grain therefrom and uses thereof. Wheat lines homozygous for the HvCslF6 gene from barley having five times the fiber content and an increased ?-glucan content of TA5790, TA5792, and TA5795 are disclosed.
Type:
Application
Filed:
December 30, 2020
Publication date:
April 29, 2021
Applicants:
General Mills, Inc., Kansas State University Research Foundation
Inventors:
Jesse Poland, Bernd Friebe, Titiana Danilova, Bikram S Gill, Eric Jackson
Abstract: A microelectromechanical device and method for neuroprosthetics comprises microactuators and microelectrodes. The microelectrodes are to be positioned in a nerve bundle and bonded with the microactuators through an interconnect. The position of each of the microactuators can be individually tuned through control signals so that the microelectrodes are implanted at desired positions in the nerve bundle. The control signals are transmitted to the microactuators and generated with a open-loop or closed-loop control scheme that uses signals acquired by the microelectrodes from the nerve bundle as feedback.
Type:
Application
Filed:
September 28, 2020
Publication date:
April 29, 2021
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Microelectromechanical system are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof. Contemplated systems are suitable for ?-ECoG arrays. Additional microelectromechanical systems are disclosed that include at least one electrode, microelectrode or combination thereof, wherein the at least one electrode comprises a carbon material, a glassy carbon material or a combination thereof; at least one substrate, surface, layer or a combination thereof, wherein the at least one electrode, microelectrode or combination thereof is disposed on, coupled with or otherwise layered on the at least one substrate, surface, layer or a combination thereof; and at least one bump pad, wherein the at least one electrode, microelectrode or combination thereof is coupled with the at least one bump pad via at least one conductive metal.
Type:
Application
Filed:
August 30, 2020
Publication date:
April 29, 2021
Applicant:
San Diego State University Research Foundation
Inventors:
Samuel Kassegne, Pieter van Niekerk, Maria Vomero
Abstract: Systems and methods for assessing reliability of electrical power transmission systems are provided. Embodiments disclosed herein use Outage Impact Index (OII), a new reliability indicator, to identify periodic (e.g., annual) system risks in transmission systems of a bulk power system (BPS) for a given voltage class. OII provides key performance indices which can be used by power utilities to quantify and assess transmission system performance, establish baselines from chronological trends, and minimize system risks by developing corrective measures to address any identified system issues.
Type:
Application
Filed:
October 23, 2020
Publication date:
April 29, 2021
Applicant:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A perfusion plate that can be combined with pillar plates containing cell layers is disclosed. The perfusion plate can have an inflow reservoir and an outflow reservoir connected by at least one channel, which fluidly connects the perfusion wells to the reservoirs for the flow of a fluid such as growth media. A perfusion plate can be part of an assembly containing a pillar plate, a lid, and a transparent bottom for visualizing cell growth in the perfusion wells. The perfusion-pillar plate assembly can facilitate perfusion-based tissue culture and tissue communication for high throughput, high-content, drug screening.
Abstract: A UV-curable and recyclable thermoset shape memory polymer is provided. The polymer includes a vitrimer-based monomer and a photoinitiator. The vitrimer-based monomer includes a first unit rendering a high chain stiffness upon polymerization of the monomer, and a second photopolymerizable unit for photopolymerization of the monomer under a UV irradiation. The polymer has high strength, high stiffness, high recovery stress, high energy storage, reasonable recycling efficiency, and is printable using SLA with high resolution.
Type:
Application
Filed:
April 30, 2019
Publication date:
April 29, 2021
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A filled and 3D printable filament is provided. In another aspect, a flexible filament comprises polyisoprene, a polymer and a filler. An aspect of a filament or fiber apparatus includes a flexible filament composition coiled around a spool, the filament or fiber composition further including polyisoprene, a polymer, and a ceramic or metallic filler. Another aspect of a filament or fiber apparatus includes a flexible filament composition further including an isoprene rubber, a polymer, a sintering aid additive, and a ceramic or metallic filler.
Type:
Application
Filed:
October 27, 2020
Publication date:
April 29, 2021
Applicant:
Board of Trustees of Michigan State University
Abstract: The application provides for MEFA constructs and vaccines against Enterotoxigenic Escherichia coli (ETEC). Methods for reducing the incidence of diarrhea associated with ETEC are also provided. The representative adhesin tip MEFAs and the representative major subunit CFA MEFA-II provided in the disclosure has an adhesin tip backbone or major subunit CFA with one or more adhesin tips, adhesin subunit or major structural subunit epitopes incorporated onto the backbone. The adhesin tip MEFAs and the CFA MEFA-II provided advantageously prevents the ETEC molecule from attaching to the intestine.
Type:
Grant
Filed:
March 20, 2017
Date of Patent:
April 27, 2021
Assignee:
Kansas State University Research Foundation
Abstract: The subject matter described herein includes a method of separating a mixture of trivalent rare-earth elements, based on their reduction potential, and solubility in a divalent state. The method includes adding the mixture of trivalent rare-earth elements to a tetraborate salt with deionized water to form a salt mixture, grinding the salt mixture with boric acid to form a solid mixture, wetting the solid mixture with water to form a paste, heating the paste to form a resultant product, dissolving the resultant product, thereby creating a residual solid in aqueous solution, wherein the residual solid includes a second mixture of trivalent rare-earth elements, and the aqueous solution includes a substantially singular element of a divalent rare-earth element in an aqueous state, and removing the residual solid, thereby separating the divalent rare-earth element from the mixture of trivalent rare-earth elements.
Abstract: Iridium, rhodium, and platinum complexes suitable for use as phosphorescent emitters or as delayed fluorescent and phosphorescent emitters have the following structure:
Type:
Grant
Filed:
October 25, 2018
Date of Patent:
April 27, 2021
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: Pennycress (Thlaspi arvense) seed, seed lots, seed meal, and compositions with reduced glucosinolate content as well as plants that yield such seed, seed lots, seed meal, and compositions are provided. Methods of making and using the pennycress plants and/or seed that provide such seed, seed lots, seed meal, and compositions are also provided.
Type:
Grant
Filed:
January 18, 2019
Date of Patent:
April 27, 2021
Assignees:
CoverCress Inc., Board of Trustees of Illinois State University, Regents of the University of Minnesota
Inventors:
Tim Ulmasov, John C. Sedbrook, Michael David Marks, Michaela G. McGinn, Ratan Chopra, Brice Allen Jarvis
Abstract: Transmission of low energy light is one of the primary loss mechanisms of a single junction solar cell. Molecular photon upconversion via triplet-triplet annihilation (TTA-UC)—combining two or more low energy photons to generate a higher energy excited state—is an intriguing strategy to surpass this limit. The present disclosure is directed to self-assembled multilayers, e.g., bi- or trilayers, on metal oxide surfaces as a strategy to facilitate TTA-UC emission and demonstrate direct charge separation of the upconverted state. A three-fold enhancement in transient photocurrent is achieved at light intensities as low as two equivalent suns.
Type:
Grant
Filed:
August 25, 2015
Date of Patent:
April 27, 2021
Assignee:
The Florida State University Research Foundation, Inc.
Inventors:
Kenneth Hanson, Sean Hill, Tristan Dilbeck
Abstract: A new solvent-based method is presented for making low-cost composite graphite electrodes containing a thermoplastic binder. The electrodes, termed thermoplastic electrodes (TPEs), are easy to fabricate and pattern, give excellent electrochemical performance, and have high conductivity (1500 S m?1). The thermoplastic binder enables the electrodes to be hot embossed, molded, templated, and/or cut with a CO2 laser into a variety of intricate patterns. These electrodes show a marked improvement in peak current, peak separation, and resistance to charge transfer over traditional carbon electrodes. The impact of electrode composition, surface treatment (sanding, polishing, plasma treatment), and graphite source were found to impact fabrication, patterning, conductivity, and electrochemical performance. Under optimized conditions, electrodes generated responses similar to more expensive and difficult to fabricate graphene and highly oriented pyrolytic graphite electrodes.
Type:
Grant
Filed:
May 22, 2020
Date of Patent:
April 27, 2021
Assignee:
Colorado State University Research Foundation
Abstract: A modular confocal microscope includes a beam steering means arranged to direct the source of electromagnetic radiation non-collinearly with the optical axis of a focusing lens. The focused non-collinearly directed source of electromagnetic radiation is used for an imaging basis of targeted one or more sites of a specimen. An arrayed detector is configured along a beam path in a conjugate confocal plane to the targeted one or more sites of the specimen. The arrayed detector is also configured to provide autocorrection information to maintain focus and image quality of the targeted one or more sites using the imaging basis. The arrayed detector provides high-throughput configured synthetic apertures in a pixel range array of N=2×2 up to an array of N=21×21.
Abstract: Compositions, thin films, devices, and methods involving doped oxide semiconductor materials are described. Indium gallium doped zinc oxide (IGZO) with advantageous properties that may be useful as a transparent conductive oxide (TCO) is described. Methods of digital doping to create doped oxide semiconductor materials are described.