Abstract: A medical tubing holder system includes a connector, a holding assembly and a retainer block. The holding assembly has an arm, and optional flanges to capture part of medical tubing, such as an endotracheal tube. The retainer block is distal from the holding assembly. The retainer block defines an aperture that receives a tube therein. The aperture is smaller than a tube flange placed between the block and the holding assembly, so as to capture the tube flange. An attachment element joins the holding assembly to the retainer block, and has length that is adjustable to selectively vary a distance between the block and the holding assembly. The attachment element effectively secures the retainer block, holding the tube flange, to the holding assembly and connector, which is secured to the patient's head, to prevent self or accidental extubation. A related method is provided.

Abstract: Systems and methods for flexible hybrid electronic (FHE) systems integrate traditional rigid integrated circuits with flexible substrates and/or interconnects. The layout and components of the system may be selected and/or optimized for a desired level of performance or flexibility. Via use of exemplary FHE system principles, improved wearable devices and other portable electronic systems may be realized.

Abstract: A portable infant incubator is provided. The incubator has a foldable circumferential wall connected to a base. The foldable circumferential wall has a first configuration folded on a top surface of the base and a second configuration standing from the top surface of the base. A cover is operatively connected to the wall when wall is in the second configuration, to provide a substantially enclosed space with the wall and the top surface of the base. An environmental control device is provided to maintain a predetermined temperature and humidity within the enclosed space. A sensor is provided to acquire environmental data and providing the data to the environmental control device.

Abstract: Tridentate cyclometalated complexes with rigid six-membered coordination rings of General Formula I having tunable emission wavelengths in the visible range. These emitters are suitable for full color displays and lighting applications.

Abstract: Disclosed herein are embodiments of sensor devices comprising a sensing component able to determine the presence of, detect, and/or quantify detectable species in a variety of environments and applications. The sensing components disclosed herein can comprise MOF materials, plasmonic nanomaterials, or combinations thereof. In an exemplary embodiment, light guides can be coupled with the sensing components described herein to provide sensor devices capable of increased NIR detection sensitivity in determining the presence of detectable species, such as gases and volatile organic compounds. In another exemplary embodiment, optical properties of the plasmonic nanomaterials combined with MOF materials can be monitored directly to detect analyte species through their impact on external conditions surrounding the particle or as a result of charge transfer to and from the plasmonic material as a result of interactions with the plasmonic material and/or the MOF material.

Abstract: A system includes a shear member and an energy absorber. The shear member is configured to couple a seat portion to a base structure of a vehicle. The shear member is configured to sustain a first load without fracture and configured to inelastically deform under a second load. The second load is greater than the first load. The energy absorber is coupled to the seat portion and coupled to the base structure. The energy absorber is configured to absorb the energy following deformation of the shear member.

Abstract: The present invention provides a compound having the structure:

Abstract: A hybrid core comprising a matrix and tubular structural reinforcements, such as a ductile matrix core reinforced with ductile hollow tubes, as well as panels which comprise such hybrid core. Embodiments of the invention manifest resistance to both interfacial debonding and ballistic penetration.

Abstract: For synthetic aperture radar (SAR) pixel vectoring, a method identifies target features of a target from a plurality of SAR signals. The method further classifies the target from the target features. In addition, the method enhances a pixel vector of the target in response to the target classification.

Abstract: Disclosed are a vehicle control unit (VCU) and an operation method thereof that calculate a speed variation of a vehicle based on input information, predict an average speed of the vehicle based on the calculated speed variation, generate a first speed profile based on the predicted average speed, and generate a second speed profile by applying speed noise information to the first speed profile.

Abstract: Processes are described for making biobased isoprene, wherein a biobased isobutene prepared from acetic acid in the presence of a catalyst is combined with a formaldehyde source to form a reaction mixture, and the reaction mixture is reacted to yield biobased isoprene. In certain embodiments, methyl-tert-butyl ether prepared by reacting the same biobased isobutene with methanol serves as a formaldehyde source, being oxidatively cracked to produce formaldehyde as well as isobutene for being converted to the biobased isoprene.

Abstract: Disclosure is provided for imidazole-phenyl derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.

Abstract: Identified herein is a novel post-translational modification of Mcm2, wherein the residue of serines 53 and 108 are phosphorylated. DDK phosphorylates Mcm2 at serines 53 and 108 when stimulated by Treslin. DDK is overexpressed in many human cancers, including colorectal cancer, suggesting that monitoring the phosphorylation of Mcm2 at serines 53 and 108 may detect early cancer with high sensitivity and specificity. It was also found that the homologous modification in budding yeast is required for DNA replication, and the modification occurs in cells during active DNA replication only. In an embodiment, the current invention is an antibody specific for human Mcm2 that is phosphorylated at serines 53 and 108. This antibody was found to be overexpressed in colon cancer cell line HCT 116, as well as other cancer cell lines, compared to normal cells.

Abstract: Methods of characterizing nanoparticles, nanoparticle complexes, and their biomolecular interactions are provided. Concurrent excitation and emission wavelength scans are performed and the optimal fluorescence intensity for the intersect of these wavelengths is determined. The intersect is dependent upon the physical characteristics of the particle and can be used to verify, for example, attachment of biomolecules, amount of biomolecules present, and structure of the attached biomolecule.

Abstract: A system and method for using the system includes a first and second waveguide and optical receiver elements coupled therebetween. The optical receiver elements include a microring configured to admit light from and transfer light to at least one of the first and second waveguides, a photodetector, coupled to the microring, configured to detect light admitted to the microring, and an enable circuit, coupled to the microring, configured to be switched between a light admitting state to enable light to be admitted to the microring and a light rejection state to prevent light from being admitted to the microring. Each optical receiver element has a relative priority and are configured to asynchronously arbitrate among themselves for a token to place one of the enable circuits in the light admitting state to enable one of the optical receiver elements to receive and transmit data.

Abstract: A system for quality assessment of optical colonoscopy images includes an input device configured to acquire a series of images during an optical colonoscopy. A computing device is coupled in communication with the input device and configured to acquire from the input device an input image from the series of images captured during the optical colonoscopy; form a cell grid including a plurality of cells on the input image; perform an image transformation onto the input image with each cell of the plurality of cells within the cell grid; reconstruct each cell to form a reconstructed image; compute a difference image of a sum of a plurality of differences between the input image and the reconstructed image; compute a histogram of the difference image; and apply a probabilistic classifier to the histogram to calculate an informativeness score for the input image.

Abstract: A method for collecting and processing remotely sensed imagery in order to achieve precise spatial co-registration (e.g., matched alignment) between multi-temporal image sets is presented. Such precise alignment or spatial co-registration of imagery can be used for change detection, image fusion, and temporal analysis/modeling. Further, images collected in this manner may be further processed in such a way that image frames or line arrays from corresponding photo stations are matched, co-aligned and if desired merged into a single image and/or subjected to the same processing sequence. A second methodology for automated detection of moving objects within a scene using a time series of remotely sensed imagery is also presented. Specialized image collection and preprocessing procedures are utilized to obtain precise spatial co-registration (image registration) between multitemporal image frame sets.

Abstract: Disclosed are peptides that exhibit good binding to the anticodon stem and loop of human lysine tRNA species, tRNALys3. The starting point was the 15-amino-acid sequence, RVTHHAFLGAHRTVG, found to bind selectively to hypermodified tRNALys3. The peptide backbone conformation was determined via atomistic simulation of the peptide-ASLLys3complex and then held fixed throughout the search. Analysis of the binding structure and the various contributions to the binding energy shows that: 1) two hydrophilic residues (asparagine (ASN) at site 11 and the cysteine (CYS) at site 12) “recognize” the ASLLys3 due to the VDW energy, and thereby contribute to its binding specificity, and 2) the positively-charged arginines (ARG) at sites 4 and 13 preferentially attract the negatively-charged sugar rings and the phosphate linkages, and thereby contribute to the binding affinity.

Abstract: One or more techniques and/or products are disclosed using a process for preparing metallic nanoparticles. Resulting nanoparticles may comprise a gold-silver-gold core-shell-shell nanoparticles. Such nanoparticles can be formed by forming a gold core, providing certain materials to form a silver shell, and providing certain materials to form a gold shell. The metallic nanoparticles may be used in molecular sensing, catalysis, photothermal therapy, and other biologically-relevant technologies.

Abstract: Methods and compositions for treating a lysosomal movement associated disease in an animal, in which the position of lysosomes can influence disease progression, comprising administering an effective amount of a first lysosome migration inhibitor or a pharmaceutically acceptable salt, solvate, clathrate, stereoisomer, enantiomer or prodrug thereof.