Abstract: The disclosure pertains to compositions to stabilize nutrient, food, pharmaceutical, and biological formulations by preventing the crystallization or precipitation of carbohydrates used in the formulations. The compositions contain (i) one or more carbohydrates, sugars, sugar alcohols, analogs thereof, and/or derivatives thereof and (ii) one or more antifreeze proteins (AFPs), mimetics thereof, and/or analogs thereof and methods of making and using the same. The AFP may be selected from antifreeze polypeptides and antifreeze peptides, analogs and mimetics of antifreeze proteins, active fragments of such antifreeze proteins, polypeptide and peptide mimetics, antifreeze peptoids and polymers, and combinations thereof.

Abstract: The present invention provides a compound having the structure: wherein X is C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, cyano, aryl, heteroaryl, alkylaryl, alkylheteroaryl, alkenylaryl, alkenylheteroaryl, alkynylaryl, alkynylheteroaryl, alkoxy, alkenyloxy, alkynyloxy, aryloxy, heteroaryloxy, acyl, alkylhydroxy, alkylamino, alkenylamino, alkynylamino, amido, carboxyl, or carboxyl ester, or forms an unsubstituted or substituted cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, indane or tetralin with Y, Y is H or forms an unsubstituted or substituted cyclobutyl, cyclopentyl, cyclohexyl, cycloheptyl, indane or tetralin with X, or forms an unsubstituted or substituted monocycle with Z; and Z is H or forms an unsubstituted or substituted monocycle with Y; wherein when X and Y are both H, then X is C2alkenyl or C2 alkynyl, and when Y is H forms a substituted cyclohexyl, cycloheptyl with X, the cyclohexyl is other than a trisubstituted cyclohexyl bearing CH3, i-Pr and (CH2)2CO2CH3 groups or CH3, i-Pr and (C

Abstract: A needle electrode is provided incorporating a protective flap and optionally a retraction chamber. By providing an impenetrable barrier covering the area of skin over the needle's tip, the protective flap protects against needle sticks that can occur when the tip of a needle electrode is pushed back out through the skin. An adhesive layer on the skin-side of the protective flap secures the needle in place without the use of a separate piece of adhesive tape. Other types of needles can incorporate flaps for protection or for securing the needle to the patient.

Abstract: Disclosed is a system and method for using visible light communication (“VLC”) to perform indoor position location. Through use of a system and method configured as set forth herein, the position of any appropriately marked person or item may be found indoors using data interconnected modules that communicate with one another via RF and visible light. A mobile receiver in the form of a tag or badge attached to the person or item to be tracked receives a VLC signal from a plurality of lighting modules, and transmits back to a processor the data it received so that the processor is able determine the tag's or badge's physical position with respect to the individual network modules.

Abstract: A method for generating a polycube representation of an input object comprises: receiving an input volumetric representation of the input object; deforming the input volumetric representation to provide a deformed object representation; and extracting, by the processor, a polycube representation of the object from the deformed object representation. Deforming the input volumetric representation to provide the deformed object representation comprises effecting a tradeoff between competing objectives of: deforming the input volumetric representation in a manner which provides surfaces having normal vectors closely aligned with one of the six directions aligned with the set of global Cartesian axes; and deforming the input volumetric representation in a manner which provides low-distortion deformations. Deforming the input volumetric representation to provide the deformed object may be performed iteratively.

Abstract: A frequency controlled electro-optical device includes a substrate having transparent conductive control sections patterned thereon to selectively control the optical state of an electro-optical layer. Each of the control sections are partially electrically isolated from each other by crack lines, which allows for electrical communication between adjacent/proximate control sections to occur. As such, an electrical control signal applied directly to one control section forms an electric field in that control section, and also induces an electrical field in adjacent control sections that are not in direct receipt of the control signal. Therefore, the number of electrical connections required for coupling to a driving circuit to operate the device is minimized, thereby allowing the device to be fabricated with reduced complexity and cost.

Abstract: Three-dimensional inductors may comprise a passivation layer disposed on a substrate, a three-dimensional pillar comprising a ferromagnetic material disposed on the substrate or the passivation layer, and a conductive trace wound at least partially around the pillar. Three-dimensional capacitors may comprise a passivation layer disposed on a substrate, at least two support pillars comprising a polymeric material disposed on the passivation layer or the substrate, at least two electrodes disposed between the support pillars, a dielectric disposed between the electrodes, and a metal trace. Methods of manufacturing the three-dimensional passives, such as inductors and capacitors, may comprise direct writing the components and curing them for on-chip applications.

Abstract: Compositions and methods for reconstituting a protein of interest in the plasma membrane of a Xenopus oocyte are disclosed. The method generally includes combining a preassembled membrane protein or proteins with a liposome to prepare a proteo-liposome. The proteo-liposome can have a specific composition of lipids. The proteo-liposome is incubated for sufficient time and under conditions suitable for the protein of interest to fold, associate with, or insert into the liposome's lipid bilayer. In some embodiments, the protein or proteins assemble into a protein channel or complex on or in the proteo-liposome's membrane. The treated oocytes can be used to determine the structure, function, or activity of the membrane protein of interest, the effect of a lipid microenvironment on a membrane protein of interest, or to identify compounds that modulate the function or activity of the membrane protein of interest.

Abstract: Disclosed herein are isotopically labeled calcofluor derivatives and uses of such to detect fungi, such as filamentous fungi, including Aspergillus species, such as by positron emission tomography (PET) scanning.

Abstract: The invention relates to a polypeptide comprising an amino acid having a norbornene group. Suitably said norbornene group is present as an amino acid residue of a norbornene lysine. The invention also relates to a method of producing a polypeptide comprising a norbornene group, said method comprising genetically incorporating an amino acid comprising a norbornene group into a polypeptide.

Abstract: A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream.

Abstract: An optical magnification system comprises two Pancharatnam lenses, and provides a first magnification for left-hand circularly polarized light and a second magnification different from the first magnification for right-hand circularly polarized light. An optical magnification system comprises two lenses, each having different focal lengths for left-handed and right-handed circularly polarized light, respectively, and configured to provide a first magnification for left-handed circularly polarized light and a second magnification different from the first magnification for right-handed circularly polarized light.

Abstract: The present disclosure provides simple ?-hairpin peptides in linear and cyclic form that specifically bind to HIV-1 Trans-Activation Response element (HIV-1 TAR), as well as compositions and use thereof.

Abstract: A rotor bearing system radially supporting a rotor, held in magnetic suspension without contact, by active radial magnetic bearing phased arrays, bearing sensors used to measure the rotor motion and bearing properties, a controller system used to adjust variable magnetic bearing parameters via amplifiers for each array element in response to bearing sensors, to change bearing local array element stiffness and damping, generating bearing forces for levitating the rotor, stabilizing rotor vibrations, and acting as a rotor vibration actuator.

Abstract: A multiscale hierarchical scaffold with the complexity of extracellular matrix (ECM) is disclosed. The multiscale hierarchical scaffold may be a carbon-based scaffold with hierarchical nanoscale and microscale architecture with controlled physicochemical properties. More specifically, multiscale hierarchy is built by growing carbon nanotube carpets on two types of scaffolds, namely, interconnected microporous carbon foams and aligned carbon fiber mats.

Abstract: A microfluidic solenoid point of use device for discrete quantitation of magnetized cells. The inventive device provides higher accuracy, lower cost, and less bulk than other counting devices.

Abstract: The present disclosure provides a fluoroscopic needle guide device for use in medical procedures that facilitate the direct targeting of a pre-identified target in a subject and methods for reaching the same with a medical device. The present disclosure includes fluoroscopic needle guide devices including detachable alignment indicators and methods for using the same.

Abstract: Methods are provided for high throughput genotyping of plants, utilizing at least three primers, one primer recognizing a polymorphic sequence of a first species of a plant genus, a second primer recognizing a second polymorphic sequence of a second species, and a third primer that recognizes sequences of both the first and second species and producing a measurable signal when amplifying a plant DNA-containing sample. Additional primers recognizing additional species may also be employed. The method may be repeated for multiple sequences each diagnosing a species or hybrid, and results analyzed using data from multiple assays to improve the statistical robustness of genotyping results. Controls are provided in which the primer target sequences are introduced into and extracted from bacteria and the measurable signal used as a control. The methods are particularly useful for genotyping a population of plants, especially where weed species and/or hybrids are present.

Abstract: A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material.

Abstract: The present invention provides a system and method for producing superconducting joints between superconductive segments of a Bi-2212 high-temperature superconducting (HTS) conductor, thereby eliminating the heat generating resistive joints that are commonly known in the art for connecting two or more smaller Bi-2212 conductive segments to create an Bi-2212 conductor of adequate length.