Abstract: Isolated or recombinant EphA5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided.

Abstract: A line-scan Brillouin microscopy apparatus is configured to operate in a coaxial configuration. The line-scan Brillouin microscopy apparatus includes an illumination source that provides a P polarized illumination light beam for illuminating a sample. A first optical assembly provides the P polarized illumination light beam to the sample and collects initial Brillouin scattered light from the sample. The first optical assembly includes an optical component that converts the initial Brillouin scattered light to S polarized Brillouin scattered light. A second optical assembly is configured to receive the S polarized Brillouin scattered light from the first optical assembly. Characteristically, the second optical assembly is configured to induce a spectral dispersion. A detection unit is configured to detect a spatio-spectral pattern of the initial Brillouin scattered light. Advantageously, multiple points of the sample along P polarized illumination light beam are measured simultaneously.

Abstract: For communicating securely between network nodes, a method transmits a port knock sequence comprising ordered empty protocol packets from an origination node to a destination Internet Protocol (IP) address of a destination node. The port knock sequence encodes at least one vocabulary phrase. The method transmits the length of the at least one vocabulary phrase to first and second helper nodes. The method generates a corresponding substitute phrase for each at least one vocabulary phrase through communication between the first helper node and the second helper node. The method receives the corresponding substitute phrase for each at least one vocabulary phrase at the origination node and the destination node. The method generates a node nonce based on the at least one corresponding substitute phrase. The method securely communicates between the origination node and the destination node using the node nonce.

Abstract: A method for using time-series data to predict remaining useful life of industrial equipment in cases where limited time-series training data is available is described. The method includes steps of monitoring the industrial equipment to sense historical time-series data associated with the industrial equipment using at least one sensor, storing the historical time-series data from the at least one sensor, accessing the historical time-series data and pre-processing the historical time-series data to extract higher-level features associated with the remaining useful life of the industrial equipment, and applying a jointly trained health predictor to the higher-level features using a computing device by executing a set of instructions from a non-transitory machine readable memory using a processor of the computing device to determine a prediction for the remaining useful life of the industrial equipment.

Abstract: A system and method for clock distribution in a digital circuit. In some embodiments, the method, includes: modifying a synchronous digital logic circuit, the modifying including: replacing a first D flipflop in the circuit with a local-clocking source flipflop; and connecting a clock output of the local-clocking source flipflop to a clock input of a second D flipflop, wherein the replacing and connecting increases an objective function, the objective function being based on the number of high drive strength cells in a logic cone preceding the second D flipflop.

Abstract: A polarimetric metastructure is disclosed that includes a metasurface structure, one or more vertically coupled double-layer metallic gratings, and a dielectric spacer layer between the metasurface structure and the vertically coupled double-layer metallic gratings.

Abstract: An unmanned aerial vehicle (UAV) for gas transport is disclosed. The UAV includes a fuselage enclosing a volume, and a gas reservoir enclosed within the fuselage, filling at least a majority of the volume. The gas reservoir is configured to receive and store a gas at a pressure no greater than 100 bar. The UAV also includes a propulsion system having at least one engine, each of the at least one engine coupled to a prop that is driven by the at least one engine using energy derived from the gas stored in the gas reservoir. The UAV also includes a control system communicatively coupled to the propulsion system and configured to operate the unmanned aerial vehicle to autonomously transport the gas. The UAV may have a footprint while on the ground, and the footprint of the UAV may be no larger than three standard parking spaces.

Abstract: The present invention discloses systems for targeted gene editing and related uses.

Abstract: An electrosurgical device (10) operable to deliver microwave energy to cause targeted tissue ablation is provided. The electrosurgical device (10) comprises an antenna (26), a reflector (30), and a dielectric material (34) disposed therebetween. The selection of the dielectric material (30) and the relative positioning of the antenna (26) and the reflector (30) provide impedance matching between the antenna (26) and a transmission line (12) so as to minimize heating along the length of the device (10) during use.

Abstract: An insect-proof, form-fitting undergarment is provided having top and bottom parts formed of selected breathable materials and having omnidirectional stretch properties, and which top and bottom parts may be securely joined at the waist to prevent insect entry. A superfine knitted fabric is utilized to prevent insect bites.

Abstract: Isothiocyanate (ITC)-androgen receptor (AR) inhibitor conjugates for apoptosis induction in cancer cells are described. The conjugates can have electrophilicity blocked with an agent such as N-acetyl cysteine. When administered in combination with a glutathione (GSH)-depleting agent, the conjugates result in ferroptosis of cancer cells.

Abstract: A control circuit is provided for a field-effect transistor with a floating source node. The control circuit includes: a charge storage device electrically connected between a gate of the field-effect transistor and a DC power supply; a gate control circuit electrically connected between the charge storage device and the gate of the field-effect transistor; and a charge control circuit electrically connected between the DC power supply and the charge storage device. The gate control circuit is configured to receive a gate control signal and operates to turn on the field-effect transistor during on time of the gate control signal and turn off the field-effect transistor during off time of the gate control signal. The charge control circuit is also configured to receive the gate control signal and operates to charge the charge storage device with power from the DC power supply during off time of the gate control signal.

Abstract: Production of a bulk Al-RE alloy body (product) using cast billets/ingots (cooling rates <100 C/s) or rapidly solidified Al-RE particulates (cooling rates 102-106° C./second) that have beneficial microstructural refinements that are further refined by subsequent consolidation to produce a consolidated bulk alloy product having excellent mechanical properties over a wide temperature range such as up to and above 230° C.

Abstract: A system and method of scheduling tasks, comprising receiving activity and performance data from registers or storage locations maintained by hardware and an operating system; storing calibration coefficients associated with the activity and performance data; computing an energy dissipation rate based on at least the activity and performance data; and scheduling tasks under the operating system based on the computed energy dissipation rate.

Abstract: One aspect of the present application relates to a method of synthesizing a thermoplastic polymer. This method includes providing a depolymerized lignin product comprising monomers and oligomers and producing lignin (meth)acrylate monomers and oligomers from the depolymerized lignin product. A thermoplastic lignin (meth)acrylate polymer is then formed by free radical polymerization of the lignin (meth)acrylate monomers and oligomers. The present application also relates to a branched chain thermoplastic lignin (meth)acrylate polymer which includes a chain transfer agent. The thermoplastic lignin based polymers of the present application can be used to prepare carbon fibers, and engineering thermoplastics. Mixtures of lignin (meth)acrylate monomers and oligomers are also disclosed.

Abstract: The invention relates to a formulation comprising: 2-undecanone in an amount of about 5% to about 50%; at least one hydrophobic base in an amount of about 5% to about 65%; at least one alcohol in an amount of about 5% to about 50%; and at least one emulsifier in an amount of about 5% to about 15% and methods of repelling insects and ticks by applying to a subject or a substrate a formulation of the invention.

Abstract: Disclosed herein are embodiments of a coating composition comprising cellulose nanomaterials and emulsion systems. The coating compositions provide improved moisture barrier and wettability onto fruit surfaces and can control physiological activity and enhance storability of food products, such as fruits during ambient storage. Also disclosed herein are embodiments of dried and substantially dried coatings, films, products made with the coating compositions, and methods of making and using the coating compositions described herein.

Abstract: A wirelessly powered resistive sensor is presented. The sensor includes: an antenna; a parametric resonator and a resistive loop circuit. The parametric resonator is configured to receive a pumping signal from the antenna and operable to oscillate at two frequencies. The resistive loop circuit is inductively coupled to the parametric resonator, such that oscillation frequency of the parametric resonator changes (e.g., linearly) with changes in resistance of the resistance loop circuit. The resistance of the resistor in the resistive loop circuit approximately equals the impedance of the resistive loop circuit at one resonance frequency of the parametric resonator. The resistive sensor may further include a resonator enhancer circuit arranged adjacent to the parametric resonator and operates to resonate at frequency of the pumping signal.

Abstract: ‘NCORNSP-032SCRHI’ is a moderately compact and loosely upright variety with a moderate growth rate and is well branched. It is distinguishable from other ornamental sweetpotato cultivars by its red to burgundy five lobed leaves, a moderately-compact habit and semi-erect mounding plant architecture. The burgundy leaves, uniform color, short internodes, and the plant architecture, which promotes good plant production in the greenhouse for wholesale distributors, distinguishes ‘NCORNSP-032SCRHI’ amongst the current ornamental sweetpotatoes in the marketplace. In greenhouse and field trials, ‘NCORNSP-032SCRHI’ is shown to be suitable for use as a landscape or containerized plant. The production of flowers by ‘NCORNSP-032SCRHI’ is not observed under short-day conditions.

Abstract: A new Bermudagrass plant particularly distinguished by having a fine leaf texture, a dark green genetic color, reduced seedhead production, fast establishment, high density, and disease resistance leafspot (Bipolaris cynodontis), is disclosed.