Abstract: For remote heart rate estimation, a method detects an object of interest (OOI) in each image of a video data and tracks the OOI in each image of the video data. The method identifies a region of interest (ROI) within the OOI and generates a plurality of super pixels from a plurality of pixels in each ROI. The method further generates a super-pixel time series from the plurality of super pixels in each image and removes interfering signals from the super-pixel time series. The method further models the super-pixel time series as a super-pixel model and calculates a heart beat signal from the super-pixel model. The method calculates heart characteristics from the heart beat signal. The heart characteristics include one or more of a heart rate, an inter-beat interval, and a heart rate variability.
Abstract: A method of modifying the amount of at least one biochemical component in a plant comprising expressing Qua-Quine Starch (QQS) in the plant, the wild-type of which does not express QQS; a transgenic plant, or part thereof, which comprises and expresses QQS as a transgene and in which the amount of at least one biochemical component is modified; a tissue culture of regenerable cells of the transgenic plant; a vector comprising a nucleotide sequence, which encodes the coding sequence of QQS, operably linked to a non-native promoter, which promotes expression of the nucleotide sequence in a plant, which is other than Arabidopsis; and a method of producing a food or industrial product from a plant.
Type:
Grant
Filed:
September 13, 2015
Date of Patent:
December 26, 2017
Assignee:
IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: Methods and compositions for modulating shoot apical meristem size are provided. Methods are provided for modulating the expression of Fea4 sequence in a host plant or plant cell to modulate agronomic characteristics such as altered size and number of organs, including plant seeds.
Type:
Grant
Filed:
March 14, 2013
Date of Patent:
December 26, 2017
Assignees:
E. I. du Pont de Nemours And Company, Cold Spring Harbor Laboratory, Iowa State University Research Foundation, Inc.
Inventors:
Stephen M Allen, David Peter Jackson, Mai Komatsu, Michael Pautler, Hajime Sakai, Erik Vollbrecht, Rebecca Weeks
Abstract: An electrochemical method for measuring the activity of enzymes using nanoelectrode arrays fabricated with vertically aligned carbon nanofibers. Short peptide substrates specific to disease-related enzymes are covalently attached to the exposed nanofiber tips. A redox moiety, such as ferrocene, can be linked at the distal end of the nanofibers. Contact of the arrays with a biological sample containing one or more target enzymes results in cleavage of the peptides and changes the redox signal of the redox moiety indicating the presence of the target enzymes.
Type:
Grant
Filed:
June 30, 2014
Date of Patent:
December 26, 2017
Assignee:
Kansas State University Research Foundation
Inventors:
Jun Li, Duy Hua, Lateef Uddin Syed, Allan Prior, Luxi Swisher
Abstract: A method and system for treating cardiac arrhythmias which includes inserting one or more electrodes into a patient's neck, and connecting the electrodes to the vagus nerve in the patient's neck. A cardiac monitoring device detects a cardiac arrhythmia. A controller connected to an electrical power source provides electrical power to the electrodes to apply electrical stimulation to the vagus nerve when a cardiac arrhythmia is detected.
Type:
Application
Filed:
June 30, 2017
Publication date:
December 21, 2017
Applicant:
The Research Foundation for The State University of New York
Inventors:
Mark Stewart, Isaac Naggar, Jason Lazar
Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided.
Abstract: A method includes sensing one or more pattern elements on a patterned contact lens on the eye of a person. Movement or direction of the person's eye is assessed based on the sensing of the one or more pattern elements. The pattern elements may be sensed using a single-pixel sensor. The pattern may include, for example, a pattern of elements having different colors.
Abstract: 2-Dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD), as well as variants, derivatives, analogs, modifications, and conjugates thereof, are identified as therapeutic agents for treating or preventing human cancers and precancerous conditions. DMDD can be isolated from the root of Averrhoa carambola L., commonly known as starfruit. Pharmaceutical and nutraceutical compositions, as well as dietary supplements, are provided, as are methods of administration and treatment.
Abstract: A method of making a synthetic foldable having a tertiary structure emulating the tertiary structure of a reference foldable protein is described. The method includes determining a folding nucleus peptide sequence associated with folding the reference foldable protein. The synthetic foldable protein is synthesized by including the determined folding nucleus peptide sequence and at least one repeat thereof in the peptide sequence of the synthetic foldable protein.
Type:
Application
Filed:
September 7, 2017
Publication date:
December 21, 2017
Applicant:
Florida State University Research Foundation, Inc.
Abstract: A system and method for collecting a core sample. The system includes an outer cylindrical tube, a drive head, a drive shoe, a cooling chamber housed inside the outer cylindrical tube, insulation, a core sample liner, an inlet tube, and outlet tube. The drive shoe further comprises a first, second, and third step, the first step configured to receive the insulation, the second step configured to receive the cooling chamber, the third step configured to receive the core sample liner, wherein the first step has a diameter larger than the second step and the second step has a diameter larger than the third step. The method includes drilling a hole in the ground with a drilling tool, enclosing a core sample by a core sample liner, freezing the core sample via a cooling liquid, retrieving the drilling tool at a surface of the ground, and removing the core sample encased in the core sample liner from the cooling chamber.
Type:
Application
Filed:
June 15, 2017
Publication date:
December 21, 2017
Applicant:
Colorado State University Research Foundation
Inventors:
Thomas C. Sale, Richard L. Johnson, Richard C. Rogers, Saeed Kiaalhosseini
Abstract: Polypeptides and other compounds that can bind specifically to the CH2-CH3 cleft of an immunoglobulin molecule, as well as methods for using such polypeptides and compounds to inhibit Fc-mediated immune complex formation in viral infection, I are described. For example, polypeptides and other compounds can be used to inhibit immune complex formation in a subject who has been diagnosed as having or is suspected of having an Ebola virus infection, a subject who has been diagnosed as having or is suspected of having an influenza virus infection, or a subject who has been diagnosed as having or is suspected of having a hepatitis virus infection.
Abstract: The present disclosure provides compositions and methods for preparing engineered porous protein crystals comprising at least one guest molecule.
Type:
Application
Filed:
June 20, 2017
Publication date:
December 21, 2017
Applicant:
Colorado State University Research Foundation
Abstract: A fiber grating device of low cost and arbitrary length is formed on a portion of a portion or the entirety of a highly elastic fiber optic core having a low Young's modulus of elasticity by causing elongation of the fiber optic core and forming or depositing a hard skin or cladding on the elongated fiber optic core. When the stress is then released, the hard skin or cladding buckles (including elastic or plastic deformation or both) to form wrinkles at the interface of the fiber optic core and the hard skin or cladding which are oriented circumferentially and highly uniform in height and spacing which can be varied at will by choice of materials, stretching, and thickness and composition of the cladding. Since the elastic elongation of the fiber optic core portion may be 200% or greater, an unprecedented measurement range is provided.
Abstract: An apparatus and device for repetitive use in automotive testing is provided. The apparatus includes a frame dimensioned in the same shape as a bicycle frame. The frame includes a first support beam and a plurality of second support beams. The apparatus further includes an elastic member elastically coupling each of the plurality of second support beams to the first support beam so as to allow the frame to separate when impacted and be easily reassembled for further testing. The device includes a disk having a first radar transparent layer opposite a second radar transparent layer and a reflective film disposed between the first radar transparent layer and the second radar transparent layer. The reflective film has a radar cross section pattern similar to that of an actual bicycle wheel when seen by automotive radar.
Type:
Grant
Filed:
June 3, 2015
Date of Patent:
December 19, 2017
Assignees:
Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Jidosha Kabushiki Kaisha, The Ohio State University, Indiana University Research and Technology Corporation
Inventors:
Stanley Yung-Ping Chien, Chi-chih Chen, Rini Sherony, Hiroyuki Takahashi, Jason Brink, Qiang Yi, Domenic Belgiovane
Abstract: The present invention relates to novel 2,5,6-benzimidazole derivatives and pharmaceutically acceptable salts thereof. Another aspect of the invention relates to methods of treating a patient infected by Mycobacterium tuberculosis by administering to the patient a 2,5,6-benzimidazole derivative or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
November 19, 2014
Date of Patent:
December 19, 2017
Assignee:
The Research Foundation for The State University of New York
Abstract: The present invention is directed to reagents useful for generating immune responses to Mycobacterium tuberculosis and for diagnosing infection and disease in a subject that has been exposed to M. tuberculosis.
Type:
Grant
Filed:
February 9, 2016
Date of Patent:
December 19, 2017
Assignee:
Rutgers, The State University of New Jersey
Abstract: A micronozzle device can include at least one layer having a plurality of nozzle exits for delivering a mixture of a first fluid and a second fluid, at least one first-fluid header layer having a plurality of first microchannels for receiving the first fluid, at least one first-fluid via layer adjacent the at least one first-fluid header layer to receive the first fluid and direct it to respective ones of the plurality of nozzle exits, at least one second-fluid header layer having a plurality of second microchannels for receiving the second fluid, at least one second-fluid via layer adjacent the at least one second-fluid header layer to receive the second fluid and direct it respective ones of the plurality of nozzle exits, and a plurality of first curtain-gas nozzles located at a first side of the micronozzle device and a plurality of second curtain-gas nozzles located at a second side of the micronozzle device.
Abstract: Systems and methods for modeling memory access behavior and memory traffic timing behavior are disclosed. According to an aspect, a method includes receiving data indicative of memory access behavior resulting from instructions executed on a processor. The method also includes determining a statistical profile of the memory access behavior, the profile including tuple statistics of memory access behavior. Further, the method includes generating a clone of the executed instructions based on the statistical profile for use in simulating the memory access behavior.
Abstract: The invention provides promoter sequences that regulate specific expression of operably linked sequences in developing xylem cells and/or in developing xylem tissue. The developing xylem-specific sequences are exemplified by the DX5, DX8, DX11, and DX15 promoters, portions thereof, and homologs thereof. The invention further provides expression vectors, cells, tissues and plants that contain the invention's sequences. The compositions of the invention and methods of using them are useful in, for example, improving the quantity (biomass) and/or the quality (wood density, lignin content, sugar content etc.) of expressed biomass feedstock products that may be used for bioenergy, biorefinary, and generating wood products such as pulp, paper, and solid wood.
Type:
Grant
Filed:
September 13, 2011
Date of Patent:
December 19, 2017
Assignee:
Board of Trustees of Michigan State University
Abstract: This disclosure includes systems and methods for extracting water vapor from atmospheric air and, more particularly, but not by way of limitation, systems and methods for optimizing liquid water production from air, in some instances, taking into account diurnal variations. The systems comprise an adsorption zone an a desorption zone, an actuator to move a desiccant between the adsorption zone and the desorption zone. The liquid water production is optimized based, at least in part, on measurements of one or more of: an ambient air temperature, ambient air relative humidity, and a level of solar insolation.
Type:
Application
Filed:
November 20, 2015
Publication date:
December 14, 2017
Applicant:
ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY