Abstract: A compound that is useful for forming a metal by reaction with a reducing agent is described by formula (I): wherein M is a metal selected from Groups 3 through 12 of the Periodic Table; R1 and R2 are each independently H or C1-C6 alkyl; and R3 is H or C1-C8 alkyl.
Type:
Grant
Filed:
December 10, 2012
Date of Patent:
December 9, 2014
Assignee:
Wayne State University
Inventors:
Charles H. Winter, Lakmal C. Kalutarage
Abstract: A fluidic device including a main channel, wherein a first inlet fluidly connects to an upstream end of the main channel and introduces magnetic beads into a first side of the main channel A second inlet is fluidly connected to the upstream end of the main channel and introduces a sample stream into a second side of the main channel A first magnet disposed adjacent to the second side of the main channel pulls the magnetic beads towards a sidewall of the second side, and thus into the sample stream A second magnet disposed downstream from the first magnet and adjacent to a first side of the main channel subsequently pulls the magnetic beads towards a sidewall of the first side, and thus out of the sample stream A detection region is disposed at or downstream from the second magnet and in the first side of the main channel.
Type:
Grant
Filed:
March 31, 2009
Date of Patent:
December 9, 2014
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Jeffrey Zahn, Lawrence Anthony Sasso, Jr.
Abstract: Methods and systems for neurostimulation and/or neurotelemetry of electrically-excitable biological tissue. Embodiments include implanting single or multiple semiconductor diodes and applying a high frequency electrical volume current. Neurostimulation embodiments include local rectification of the volume current by the diode, which can provide a pulsating electrical waveform capable of locally stimulating neural tissue, hi neurotelemetry embodiments, semiconductor diodes can be placed in contact with excitable tissue and a low level electrical carrier wave can be passed through the tissue and implanted diode whereby low level tissue bioelectric events intermodulate with the carrier wave and encode bioelectrical effects.
Type:
Grant
Filed:
May 21, 2010
Date of Patent:
December 9, 2014
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: The present invention provides a novel process and system in which a mixture of carbon monoxide and hydrogen synthesis gas, or syngas, is converted into hydrocarbon mixtures composed of high quality gasoline components, aromatic compounds, and lower molecular weight gaseous olefins in one reactor or step. The invention utilizes a novel molybdenum-zeolite catalyst in high pressure hydrogen for conversion, as well as a novel rhenium-zeolite catalyst in place of the molybdenum-zeolite catalyst, and provides for use of the novel catalysts in the process and system of the invention.
Abstract: A magnetic platform is provided and includes a patterned array of discrete magnetic elements positioned on a substrate, a plurality of first electromagnets for creating a first magnetic field substantially in the plane of the substrate, an electromagnetic coil for creating a second magnetic field substantially perpendicular to the plane of the substrate, and a control device for controlling the application of the magnetic fields. Processes for manipulating, transporting, separating and sorting micro-or nano-scale particles and biomolecules are also described.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
December 9, 2014
Assignee:
The Ohio State University
Inventors:
Ratnasingham Sooryakumar, Thomas Charles Henighan, Gregory B. Vieira, Jeffrey J. Chalmers
Abstract: Polysaccharide-containing extracts isolated from a host cell containing nucleotide sequences encoding genes pamA, pamB and pamC, wherein the extract is capable of inhibiting biofilm formation produced by gram-negative bacteria, gram-positive bacteria and fungi, and methods to inhibit biofilm formation or remove biofilms that have already formed.
Type:
Grant
Filed:
January 26, 2012
Date of Patent:
December 9, 2014
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Jeffrey B. Kaplan, Nataliya V. Balashova, Scott C. Kachlany, Evguenii Vinogradov
Abstract: Systems and methods are disclosed with which queries can be sent to various clients of a trusted query network in a trusted query network message. In one embodiment, each registered client receives the message and determines whether or not it will participate in the query. If so, the client adds to the message in a first data round a true response to the query and obfuscation data, and then forwards the message on to the next client (or back to the client that initiated the query if each client has added its data to the message). In a second round, the message is again sent to each participating client, which this time removes its obfuscation data. Once each client has removed its obfuscation data, a final result is obtained that can be sent to each of the clients.
Type:
Grant
Filed:
July 16, 2010
Date of Patent:
December 9, 2014
Assignee:
Georgia State University Research Foundation, Inc.
Inventors:
Richard Baskerville, Art Vandenberg, Daniele Bertolotti, Saravanaraj Duraisamy
Abstract: A technique is provided to visualize microtubules in live cells that does not require genetic manipulation or microinjection. Moreover, this method also avoids perturbation of the endogenous microtubule network that occurs with taxol treatment. This technique exploits tyrosination and detyrosination of tubulin, a posttranslational modification cycle specific to the C-terminus of ?-tubulin. Specifically, cells are grown in medium supplemented with a tyrosine derivative possessing a reactive functional group. The cellular enzyme tubulin tyrosine ligase attaches the unnatural amino acid to a single site on tubulin. Addition of fresh medium containing a suitably derivatized fluorophore then yields fluorescent tubulin, which incorporate into cellular microtubules. Importantly, the tubulin labeling approach demonstrated here does not detrimentally affect microtubule network or cell morphology. Thus we present a simple, robust labeling technique that allows microscopic analysis of microtubules in live cells.
Type:
Application
Filed:
June 2, 2014
Publication date:
December 4, 2014
Applicant:
The Research Foundation for The State University of New York
Abstract: The present disclosure relates to nanosheet synthesis. More particularly, the present disclosure relates to molybdenum sulfide (MoS2) atomic thin films and hydrogen evolution reactions. In one or more embodiments, a synthesis process may include sublimation of sulfur and MoCl5, reaction of MoCl5 and S to produce gaseous MoS2 species, transfer of the MoS2 species by carrier gas, diffusion of MoS2 species from the gas phase onto receiving substrates, and precipitation of MoS2 on the substrates.
Type:
Application
Filed:
May 9, 2014
Publication date:
December 4, 2014
Applicant:
North Carolina State University
Inventors:
Brian C. Iezzi, Yanpeng Li, Linyou Cao, Yifei Yu
Abstract: A processor comprising: an instruction processing pipeline, configured to receive a sequence of instructions for execution, said sequence comprising at least one instruction including a flow control instruction which terminates the sequence; a hash generator, configured to generate a hash associated with execution of the sequence of instructions; a memory configured to securely receive a reference signature corresponding to a hash of a verified corresponding sequence of instructions; verification logic configured to determine a correspondence between the hash and the reference signature; and authorization logic configured to selectively produce a signal, in dependence on a degree of correspondence of the hash with the reference signature.
Type:
Grant
Filed:
July 15, 2011
Date of Patent:
December 2, 2014
Assignee:
The Research Foundation for The State University of New York
Abstract: Methods, systems, and computer readable media for low power multimode interconnect for lossy and tightly coupled multi-channel are disclosed. According to one aspect, a system for low power multimode interconnect includes a receiver for receiving a plurality of input signals that have been encoded by a multimode encoding equation to have voltage levels according to the multimode encoding equation and for decoding the received signals according to a multimode decoding equation to produce binary data as output, wherein the receiver includes a set of frequency-compensated amplifiers for emphasizing high-frequency components of the received input signals and a set of latches for receiving amplified signals from the frequency-compensated amplifiers and for decoding the amplified signals according to the multimode decoding equation to produce binary data as output.
Abstract: The present application relates at least in part to methods for the administration of small interfering RNAs (siRNAs) to the spinal cord of a human or animal patient and also to a method of treatment for spinal cord injury and other diseases and disorders of the CNS. In particular, the application discloses methods to deliver an siRNA compound locally, directly and without the need for transduction vehicles and formulations in effective doses to the injured spinal cord to promote recovery of CNS function and or attenuation of allodynia.
Type:
Grant
Filed:
November 8, 2010
Date of Patent:
December 2, 2014
Assignees:
Quark Pharmaceuticals, Inc., Rutgers, The State University of New Jersey
Abstract: A combustion chamber, having an upper part and a lower part, may include an annular constriction, in combination with the combustion chamber, to aid in directing partially combusted gases such as carbon monoxide away from the periphery of the combustion chamber back toward its center, and into the flame front. The annular constriction may also impede the flow of partially combusted gases located at the periphery, thus increasing the time these gases spend within the combustion chamber and increasing the likelihood that any products of incomplete combustion will undergo combustion. The combustion chamber may further comprise a dual burner cooktop for directing combustion gases and exhaust to multiple cooking vessels. In further embodiments, the combustion chamber may be made of, lined, or clad with a metal alloy comprising iron, chromium, and aluminum.
Type:
Grant
Filed:
April 8, 2010
Date of Patent:
December 2, 2014
Assignees:
Colorado State University Research Foundation, UT-Battelle, LLC
Inventors:
Morgan W. DeFoort, Bryan D. Willson, Nathan Lorenz, Michael P. Brady, Anthony Marchese, Daniel D. Miller-Lionberg
Abstract: A method of generating spurious-noise-free power from a switching device. The method includes generating an oscillating signal in the form of a series of pulse trains, and randomly changing the switching frequency, or the on-time, or both the switching frequency and the on-time of the switching device. The method further includes causing the switching device to change from a first frequency to a second frequency only at the end of a pulse train of the first frequency, and causing the second frequency to start at the beginning of its first pulse train such that no switching duty-cycle disturbance at the time of the change from first to second frequency. In a particular embodiment, the method further generates spurious-noise-free power from a switching device by implementing a relationship between the different switching frequencies involved such that spurious-noise-free operation is achieved.
Type:
Grant
Filed:
February 15, 2012
Date of Patent:
December 2, 2014
Assignee:
Iowa State University Research Foundation, Inc.
Abstract: The present invention relates to the diagnosis and treatment of cancer, and in particular breast cancer. Specifically, in some embodiments the invention relates to methods of diagnosing cancer, and in particular breast cancer, using an antibody specific for a gene product that localizes selectively to the endoplasmic reticulum of the cancer cell(s). In some embodiments, the invention relates to methods of treating cancer, and in particular breast cancer, by administering a composition comprising an RNA interference sequence (e.g., shRNA, RNAi and/or siRNA molecule) characterized by an ability to inhibit an mRNA molecule, which mRNA molecule is encoded by the C43 gene (SEQ ID NO: 1). The invention additionally relates to methods for detecting cancer cells by detecting reduced methylation of the C43 promoter, and methods for reducing cancer metastasis by using demethylation inhibitors that result in increased methylation of the C43 promoter.
Type:
Grant
Filed:
July 20, 2009
Date of Patent:
December 2, 2014
Assignee:
The Research Foundation for the State University of New York
Abstract: A strategy is described for annotating a digital map. According to one exemplary aspect, the user can link a single uploaded object to multiple locations within a map (or maps) without requiring separate uploading and storing operations. According to another exemplary aspect, the user can specify a range of zoom levels in which an object is made visible on the map. According to another exemplary aspect, the user can instruct map processing functionality (MPF) to automatically extract objects from a data source (such as an RSS data source) and annotate the map with the objects. Still further aspects are described.
Abstract: Methods and compositions to temporarily delay the ripening, maturation, senescence and pathogen infection of produce such as fruits, vegetables and ornamental plants are provided. The methods involve the application of a photosynthetic pigment and/or membrane stabilizing chemical (e.g. glycine betaine) to produce which is identified as in need of such delay. Application may be prior to harvest, at or during harvest or post-harvest.
Abstract: A network of sensors is associated with a power distribution network. Sensors are positioned at each connecting line in the vicinity of each node of the power distribution network. The sensors regularly report the following measured data to the central processing unit: a geographical position of each sensor, direction of the energy flow relative to the nearest node; and value of RMS current synchronously measured over the entire network and averaged over chosen averaging period. The central processing unit includes an arrangement for receiving the measured data and using this data for constructing and updating a graph and a state of the power distribution network.
Type:
Application
Filed:
May 21, 2014
Publication date:
November 27, 2014
Applicant:
The Research Foundation for the State University of New York
Inventors:
Mikhail Gouzman, Serge Luryi, Satya Sharma, Peter Shkolnikov
Abstract: An electron microscope is provided. In another aspect, an electron microscope employs a radio frequency which acts upon electrons used to assist in imaging a specimen. Furthermore, another aspect provides an electron beam microscope with a time resolution of less than 1 picosecond with more than 105 electrons in a single shot or image group. Yet another aspect employs a super-cooled component in an electron microscope.
Type:
Application
Filed:
August 6, 2014
Publication date:
November 27, 2014
Applicant:
Board of Trustees of Michigan State University
Inventors:
Chong-Yu Ruan, Martin Berz, Zhensheng Tao