Abstract: Wettable structures that retain liquid layers are defined at surfaces of substrates. The wettable structures include grooves or ridges that are spaced apart by between 10 nm and 10 ?m and can be defined in substrate or in a layer formed on a surface of the substrate. In typical examples, wettable structures are defined with hydrophobic materials or at hydrophobic surfaces and produce hydrophilic surfaces.
Type:
Grant
Filed:
May 11, 2022
Date of Patent:
June 3, 2025
Assignees:
Montana State University, Board of Regents of the University of Nebraska
Abstract: The present disclosure provides methods of treating a human having a disease or disorder that would benefit from increasing platelet counts. The method involves inhibiting the enzyme activity of biliverdin IX? reductase (BLVRB) activity or inhibiting the expression of BLVRB gene.
Type:
Application
Filed:
February 5, 2025
Publication date:
May 29, 2025
Applicant:
The Research Foundation for The State University of New York
Abstract: Reagents and aqueous solutions thereof are described that are useful for aqueous processing to form thin films comprising metal oxides. A film, or layered film, may be incorporated into working devices where the thin film provides useful optical properties, electrical properties, or both.
Abstract: Compositions comprising biologically active synthetic nanoparticle constructs and methods of use thereof to modify mitochondrial gene expression including transcriptional repression and transcriptional activation.
Type:
Application
Filed:
October 9, 2024
Publication date:
May 29, 2025
Applicant:
Rutgers, The State University of New Jersey
Abstract: Tetradentate and octahedral metal complexes suitable for use as phosphorescent or delayed fluorescent and phosphorescent emitters in display and lighting applications.
Type:
Grant
Filed:
September 16, 2022
Date of Patent:
May 27, 2025
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: A tunable stiffness bone rod promotes the healing of fractured bones, such as tibia bones. The tunable stiffness bone rod includes a hexagonal shape that has variable levels of stiffness upon application of an axial force. The axial force will begin a low stiffness movement of the bone rod until a threshold is met. Upon reaching the threshold, the stiffness of the bone rod increases to lessen additional longitudinal movement caused by the axial force on the bone rod.
Type:
Grant
Filed:
June 17, 2021
Date of Patent:
May 27, 2025
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Azadeh Sheidaei, Mohammad Saber Hashemi, Karl Kraus
Abstract: A heat exchanger and method of making same are disclosed. In another aspect, a method of making a heat exchanger includes sintering powder metal and hot isostatic pressing of the powder metal. Moreover, an aspect of the present heat exchanger apparatus employs plates in a stacked arrangement with supercritical-CO2 flowing between the plates and between adjacent fins. Still another aspect of a heat exchanger apparatus is made of a nickel-based alloy.
Type:
Grant
Filed:
July 2, 2020
Date of Patent:
May 27, 2025
Assignee:
Board of Trustees of Michigan State University
Inventors:
James F. Klausner, André Bénard, Patrick Youngseon Kwon, Haseung Chung, Himanshu Sahasrabudhe
Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided.
Abstract: A system and associated methods apply text and network analysis methods to process information from online university researcher profiles and community organization websites to identify topics and shared interests that the groups have in common. The system includes a search platform that enables users to enter their name, their organization name, or a research topic and identify entities with similar work topics of interest. The system packages entity information and shared topic information into edge lists for ease of recall, and facilitates communication between entities.
Type:
Grant
Filed:
September 4, 2023
Date of Patent:
May 27, 2025
Assignee:
Arizona Board of Regents on Behalf of Arizona State University
Inventors:
Mason Mathews, Brajesh Karna, Patricia Solis
Abstract: A system and method for concurrent encryption and lossless compression of data with an algorithm executing on a computer platform. The lossless compression component of the algorithm consists of preprocessing the data with a Burrows-Wheeler transformation followed by an inversion ranking transformation in advance of employing an entropy coder, such as binary arithmetic coder. The frequency vector of the Inversion Ranking transformation is then encrypted and transmitted along with the compressed data with only the frequency vector encrypted. Since the frequency vector is required for decompression, no further encryption of the compressed data is necessary to secure the compressed file.
Type:
Grant
Filed:
March 9, 2023
Date of Patent:
May 27, 2025
Assignee:
The Research Foundation for the State University of New York
Abstract: A system and methods for optically detecting a target gas are disclosed and described. An imaging system can include a narrow-band optical interference filter with a center wavelength that corresponds to a feature in an absorption spectrum of a target gas at a normal angle of incidence. An optical component can receive incoming light from the target gas that has passed through the narrow-band optical interference filter, where the narrow-band optical interference filter is tilted relative to the optical component, which tilt shifts the wavelength of light from each target point that is able to pass through the narrow-band optical interference filter. A camera can receive the incoming light that has been focused by the optical component. Multiple image frames are collected for different orientations of the system with respect to the target and analyzed to perform hyperspectral charactetization of target gas absorption.
Abstract: An inductive-capacitive resonant sensor architecture includes an inductively-coupled extender (ICE) that can both increase read range and lessen the effects of reader/sensor misalignment. The ICE can include a first coil configured with respect to a resonant sensor and a second coil separated from the first coil and coupled to the first coil by electrical wires. An external reader can be arranged with respect to the second coil. This architecture can nearly eliminate misalignment issues between the external reader and the resonant sensor. The ICE can be implemented with a closed circuit design. Additional apparatus, systems, and methods are disclosed.
Type:
Grant
Filed:
August 18, 2022
Date of Patent:
May 27, 2025
Assignee:
Iowa State University Research Foundation, Inc.
Inventors:
Yee Jher Chan, Adam Russell Carr, Nigel Forest Reuel
Abstract: The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets.
Type:
Grant
Filed:
August 29, 2022
Date of Patent:
May 27, 2025
Assignee:
The South Dakota Board of Regents, As Governing Board for South Dakota State University
Abstract: A dendrimer that includes: (a) a central core; and (b)(i) at least one 2-deoxyglucose-surfaced branching units conjugated to the central core; or (b)(ii) at least one trehalose-surfaced branching units conjugated to the central core; or (b)(iii) at least one 2-deoxyglucose-surfaced branching units conjugated to the central core and at least one trehalose-surfaced branching units conjugated to the central core.
Type:
Application
Filed:
November 21, 2024
Publication date:
May 22, 2025
Applicant:
Washington State University
Inventors:
Anjali Sharma, Rishi Sharma, Anubhav Dhull, Anu Rani
Abstract: Methods of expanding a population of immune cells, such as natural killer cells or CAR-modified natural killer cells, using exosomes, and methods of producing the exosomes from a population of 721.221 cells transduced or transfected with a membrane-bound IL-21 (mIL-21) or a population of 721.22 cells transduced or transfected with a mIL-21 and B7-H6. Methods of treating a cancer or an infectious or immune disease, wherein immune cells expanded using the exosomes are administered to a subject with the cancer or the infectious or immune disease are also provided.
Type:
Application
Filed:
January 26, 2023
Publication date:
May 15, 2025
Applicant:
Rutgers, The State University of New Jersey
Abstract: Systems and methods (S/M) to detect stress in stem cells are described. The S/M, including modified stem cells, assays and high throughput screens, can be used to identify compounds or other potential stressors that can negatively affect development potential.
Abstract: Disclosed herein are embodiments of compounds that exhibit Crk-like protein inhibition. The compound embodiments can be used to suppress or prevent tumor cell growth and/or to inhibit a Crk-mediated signaling pathway. Methods of making and using the compound embodiments are disclosed herein.
Type:
Application
Filed:
February 1, 2023
Publication date:
May 15, 2025
Applicant:
Rutgers, The State University of New Jersey
Inventors:
Dongfang Liu, Xuening Wang, Jacques Roberge