Abstract: The invention provides methods and compositions that are useful for treating allergic diseases, bacterial infections, fungal infections, viral infections, mastocytosis, mast cell-mediated inflammation and parasite infections (e.g., helminth infections).

Abstract: Methods and formulations for use of phase change materials (PCMs) as coatings or integrated with building materials are disclosed. A formulation comprises an amount of phase change material, for example a mass fraction of about 0.01 to about 0.50. The PCM materials may be applied as a surface treatment such as paint, for example in order to provide improved thermal regulation to a building or a portion thereof.

Abstract: Modified ribosomes that were selected using a dipeptidyl-puromycin aminonucleoside are used to mediate site-specific incorporation of one or more peptides and peptidomimetics into protein in a cell free translation system. In addition, new fluorescent dipeptidomimetics have been synthesized and incorporated into proteins, as well as modified proteins containing one or more non-naturally occurring dipeptides.

Abstract: Systems, devices, and methods are described for controlling, and communicating with, unmanned aerial vehicles (UAVs) over a millimeter wave (mmWave) communication network established between a base station and the UAVs. A communication system may include one or more unmanned aerial vehicles (UAVs). The communication system may further include one or more base stations including millimeter wave (mmWave) antennas configured to generate control signals to the one or more UAVs over an mmWave communication network.

Abstract: Embodiments of the present application are directed toward a focusing Schlieren technique that is capable of adding color-coded directional information to the visualization of density gradients. Other advantages of the technique can include that it does not require manual calibration, has a simple design and is sensitive enough to be used in compact experimental setups. Certain embodiments include the use of a color-coded source image that replaces the conventional source grid. The technique may benefit from a computer-controlled digital background, which is used for both illumination and display of color-coded source images.

Abstract: This invention relates to recombinant Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) arrays and recombinant nucleic acid constructs encoding Type I-E CASCADE complexes, plasmids, retroviruses and bacteriophage comprising the same, and methods of use thereof for killing one or more cells in a population of bacterial and/or archaeal cells.

Abstract: The present disclosure provides compounds which are useful for a number of catalytic transformations of organic molecules, non-limiting examples including dehydrogenation of alkanes. The present disclosure further relates to methods of preparing the compounds of the present disclosure.

Abstract: A subspace-based approach to synchrophasor estimation is provided. Embodiments described herein provide two improvements to subspace-based phasor measurement unit (PMU) algorithms based on estimation of signal parameters via rotational invariance techniques (ESPRIT) frequency estimation. The first is a dynamic, real-time thresholding method to determine the size of the signal subspace. This allows for accurate ESPRIT-based frequency estimates of the nominal system frequency as well as the frequencies of any out-of-band interference or harmonic frequencies. Since other frequencies are included in the least squares (LS) estimate, the interference from frequencies other than nominal can be excluded. This results in a near flat estimation error over changes in a) nominal system frequency, b) harmonic distortion, and c) out-of-band interference. Second, the computational burden of ESPRIT is reduced and the proposed algorithm runs in real time on resource-constrained platforms.

Abstract: Thermally activated delayed fluorescence chromophores may comprise a donor ligand, an acceptor ligand, and an acceptor tuner ligand. The donor ligand may be selected from one or more of carbazole, diphenylamine, phenothiazine, phenoxazine, or acridine. The acceptor ligand may be selected from one or more of benzoxazole, benzothiazole, or diphenyl sulfone. The acceptor tuner ligand may comprise a benzene ring. The benzene ring may be at least partially substituted. Organic layers, such as polymers or films, comprising the thermally activated delayed fluorescence chromophores are also disclosed.

Abstract: A microwave capillary nanodiamond reactor assembly, and methods of making and using same, are provided. In another aspect, a reactor and method use less than 100 W of microwave power within a cavity to create a plasma therein, so a substrate or workpiece is placed in a cool plasma zone of about 350-400° C., while growing diamond on the workpiece in a low temperature synthesis manner. In another aspect, a workpiece is moved within a diamond-growing reactor while plasma is in a plasma cavity of the reactor. Furthermore, an aspect of the present reactor and method moves a plasma generating head of a reactor relative to a workpiece while the workpiece is in the reactor.

Abstract: The invention provides a compound having the structure: wherein R1 and R2 are each independently H, halogen, —NO2, —CN, —NHR14, —NR14R15, —SR14, —SO2R14, —OR14, —CO2R14, —CF3, -alkyl-NR14R15, -alkyl-OR14, C1-10 alkyl, C2-10 alkenyl, or C2-10 alkynyl; or wherein R1 and R2 together formed into a cycloalkyl or cycloheteroalkyl; wherein R3 and R7 are each independently H, halogen, —NO2, —CN, —NHR14, —NR14R15, —SR14, —SO2R14, —OR14, —CO2R14, —CF3, -alkyl-NR14R15, C1-10 alkyl, C2-10 alkenyl or C2-10 alkynyl; wherein R4 and R6 are each independently H, —NO2, —SR14, —SO2R14, —OR14, —CO2R14, -alkyl-NR14R15, -alkyl-OR14, C2-10 alkenyl or C2-10 alkynyl; wherein R5 is —NO2, —NHR14, —NR14R15, —SR14, —SO2R14, —(C?O)—NH—R14, —CO2R14, -alkyl-NR14R15, -alkyl- OR14, C2-10 alkenyl, C2-10 alkynyl, —(C0-10 alkyl)-heterocyclyl, wherein R8, R9, R10, and R11 are each independently N or CH; wherein R12 is C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl, cycloalkyl, cycloheteroalky, or heterocyclyl; wherein

Abstract: The present invention discloses a system for targeted gene editing and related uses.

Abstract: Described is an apparatus and ultrabroadband photoconduction microscopy method for measuring full sub-bandgap density of defect states in semiconductor transistors and devices. The apparatus comprises tunable laser coupled to a reflective-optic-based microscope using all-reflective optical laser to spectrally and spatially illuminate near the diffraction-limit. The method developed measures the photoconduction signal in semiconductor devices at stepwise incident energies that roughly span the full bandgap from the valence band to the conduction band edge regions. The resulting photoconduction spectrum is directly proportional to the integrated trap density by an analytically extracted scaling factor. Finally, the end-product is a complete sub-gap density of states for a semiconductor device.

Abstract: Aspects of the present disclosure include a jet impingement cooling system configured to cool high heat flux devices via a cooling fluid. The jet impingement cooling system may include a heatsink and a first supply surface. The heatsink is coupled to the high heat flux device or capable of being coupled to the high heat flux device. The heatsink includes a first impingement surface having exit orifices and impingement regions. The exit orifices are spaced-apart from each other and defined in the first impingement surface. The impingement regions are located between adjacent exit orifices. The first supply surface is spaced-apart from the first impingement surface and includes injection ports spaced-apart from each other and defined in the supply surface. The injection ports are oriented such that impingement jets therefrom are directed to impinge against the impingement regions.

Abstract: The present disclosure is directed to a multi-variant control system for an industrial facility. In one form of a method, a processor monitors a behavior of a distributed control system with respect to at least a set of uncontrolled variables, a set of controlled variables, and a set of monitored variables; trains a model based on the monitored behavior utilizing at least one of artificial intelligence or machine learning; and identifies, based on the model, a subset of controlled variables for optimization. Further, the processor monitors a behavior of the industrial facility without the use of the distributed control system; optimizes, based on the monitored behavior, the subset of controlled variables to obtain a target result and restrict variation of values of the set of monitored values; and executes a control system for the industrial facility based on the optimization of the subset of controlled variables.

Abstract: Described herein are means for generating source models for transfer learning to application specific models used in the processing of medical imaging.

Abstract: A method of making nanoparticles including a semiconducting nitride is provided. The method includes reacting precursors in a gas phase to form the nanoparticles including the semiconducting nitride. The precursors include at least one of a gallium (Ga) precursor or an indium (In) precursor and a nitrogen (N) precursor. The semiconducting nitride is In1?xGaxN, where 0?x?1. Structures that include the nanoparticles and systems for making the nanoparticles are also provided.

Abstract: Provided herein are systems for the label-free detection of target molecules in samples. The systems include a sensor probe positioned in a sensing region and configured to bind to receptors for the target molecules. The systems also include electrodes configured to expose the sensor probe to an alternating electric field, and a light source optically coupled to the sensor probe and configured to provide light along a length of the sensor probe. In addition, the systems also include a position sensitive photodetector configured to detect a position of light exiting the sensor probe, and a processor configured to assess, based at least in part on the position of the light exiting the sensor probe, an amplitude of oscillation of the sensor at a frequency of the alternating electric field and a direction of a displacement of the sensor. Additional systems and related methods are also provided.

Abstract: Disclosed herein are compounds useful for treating obstructive lung diseases. The compounds are TAS2Rs agonists and may further be used to treat disorders and conditions implicated by TAS2R. In some instances the disclosed compounds can be used to treat asthma.

Abstract: Compositions including a thermosetting polymer network and a mechanophore covalently bonded to the thermosetting polymer network are provided. Substrates including the compositions are provided. In addition, methods of making the compositions and methods of monitoring stress on a substrate comprising the compositions are provided.