Patents Assigned to State University
  • ULTRASOUND, PHOTOACOUSTIC, AND VISCOELASTIC IMAGING SYSTEMS AND METHODS FOR CERVICAL ANALYSIS TO ASSESS RISK OF PRETERM DELIVERY
    Publication number: 20240115190
    Abstract: Methods and system are described for multi-modal, multi-parametric, non-invasive, and real-time assessment of cervical tissue through a multi-modal probe device for use within a vaginal canal and an associated imaging system to assess a risk of preterm delivery of an expectant mother. The multi-modal system may include ultrasound (US) imaging, viscoelastic (VE) imaging, and/or photoacoustic (PA) imaging of the cervical issue to determine cervical biomarker information indicative of parameters including, but not limited to, a collagen to water ratio such that a more water dominant ratio is indicative of a risk of preterm delivery.
    Type: Application
    Filed: September 22, 2023
    Publication date: April 11, 2024
    Applicant: Wayne State University
    Inventors: Mohammad Mehrmohammadi, Sonia S. Hassan, Edgar Hernandez-Andrade, Yan Yan, Maryam Basij, Nardhy Gomez-Lopez
  • CRITICAL ANGLE REFLECTION IMAGING FOR QUANTIFICATION OF MOLECULAR INTERACTIONS
    Publication number: 20240118200
    Abstract: This disclosure describes systems and methods for critical angle reflection (CAR) imaging to quantify molecular binding kinetics on a glass surface in some embodiments. CAR is a label-free method that measures the reflectivity change near a critical angle in response to molecular binding induced refractive index changes on the sensor surface. The sensitivity and dynamic range of CAR is tunable by varying the incident angle of light, which allows for optimizing the measurement for ligands with different sizes in both biomolecular and cell-based studies.
    Type: Application
    Filed: December 6, 2021
    Publication date: April 11, 2024
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Shaopeng WANG, Runli LIANG, Guangzhong MA
  • POSITRON IMAGING TOMOGRAPHY IMAGING AGENT COMPOSITION ADN METHOD FOR BACTERIAL INFECTION
    Publication number: 20240115221
    Abstract: The present invention provides a composition comprising the compound having the structure: or a salt of the compound; 4-amino-2-[19F]-fluorobenzoic acid or a salt of 4-amino-2-[19F]-fluorobenzoic acid; and at least one acceptable carrier.
    Type: Application
    Filed: November 16, 2023
    Publication date: April 11, 2024
    Applicant: The Research Foundation for the State University of New York
    Inventors: Peter Tonge, Zhuo ZHANG, Peter Smith-Jones, Li LIU, Hui WANG
  • PERMEABLE PAVEMENT SYSTEM INCLUDING A PERMEABLE PAVEMENT COMPOSITION AND A RELATED METHOD
    Publication number: 20240116812
    Abstract: A permeable pavement and cured fiber composition and a related method are provided. The permeable pavement composition includes a quantity of pavement material, and a quantity of cured carbon fiber composite material (CCFCM) configured to be added to the pavement material to produce a reinforced composition having improved characteristics. An example of pavement material includes a pervious concrete material. The method includes providing a quantity of pavement material and adding a quantity of cured carbon fiber composite material to the pavement material to produce a reinforced composition having improved characteristics.
    Type: Application
    Filed: December 13, 2023
    Publication date: April 11, 2024
    Applicants: The Boeing Company, Washington State University
    Inventors: Karl Richard Englund, Somayeh Nassiri, Liv Martha Haselbach, Hui Li, Haifang Wen, Kenneth W. Fischer
  • OXIDATION RESISTANT HIGH CONDUCTIVITY COPPER ALLOYS
    Publication number: 20240116110
    Abstract: A micro-alloyed copper powder was produced using gas atomization reaction synthesis, with the alloy preferably comprising Cu-0.3Zr-0.15Ag wt. %. The novel copper alloy improves the manufacturability of copper in powder bed fusion manufacturing processes by minimizing or avoiding the prior art problems associated with oxidation of the copper precursor used in additive manufacturing. Advantageously, the provided copper alloy powder maintains the high electrical conductivity of copper while addressing the prior art oxidation issue.
    Type: Application
    Filed: December 15, 2022
    Publication date: April 11, 2024
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Christian Gentry Miles Barr, Timothy Prost
  • Antibody-Drug Conjugates Against the Receptor Tyrosine Kinase EphA5
    Publication number: 20240115722
    Abstract: The present invention relates in certain aspects to antibodies, binding polypeptides, and immunoconjugates specific for human EPH receptor A5 (EphA5).
    Type: Application
    Filed: July 27, 2023
    Publication date: April 11, 2024
    Applicants: Rutgers, The State University of New Jersey, MBrace Therapeutics, Inc.
    Inventors: Renata Pasqualini, Wadih Arap, Fernanda I. Staquicini
  • USE OF PROTEASOME INHIBITORS IN THE TREATMENT OF CORONAVIRUS INFECTIONS
    Publication number: 20240115588
    Abstract: Oral formulations comprising one or more proteasome inhibitors for use as a treatment of coronavirus infection in a subject. Also disclosed are the use of such for the treatment or prevention of SARS-CoV-2 infection in humans.
    Type: Application
    Filed: February 1, 2022
    Publication date: April 11, 2024
    Applicants: Board of Supervisors of Louisiana state University and Agricultural and Mechanical College, Skymount Medical US lnc.
    Inventors: Adam Bess, Frej Knut Gosta BERGLIND, Supratik MUKHOPADHYAY, Kishor M. WASAN, Chris GALLIANO, Michal BRYLINSKI, Stephania CORMIER, Allan ADER, Nicholas GRIGGS, Janet GOULD, Tiffany CHO, Julia ABRAMOV, Peter HNIK
  • FLUORIDE CATALYZED POLYSILOXANE DEPOLYMERIZATION
    Publication number: 20240117143
    Abstract: Methods and kits for depolymerizing a siloxane polymer, and methods for recycling a material comprising silicone, are described.
    Type: Application
    Filed: January 31, 2022
    Publication date: April 11, 2024
    Applicant: Bowling Green State University
    Inventors: Joseph Coy Furgal, Buddhima Rupasinghe
  • METHODS AND SYSTEMS FOR DETERMINING THE DISTRIBUTION OF RADIATION DOSE AND RESPONSE
    Publication number: 20240115881
    Abstract: A system, method and computer program product to determine radiation dose from radionuclides used to treat a patient in need thereof. The present invention allows users to visualize and understand the impact of radionuclide choice, distribution of activity in the cell, distribution of activity among the cells, cell dimensions, cell separation distance, cluster size, and radiobiological response parameters on the capacity to kill populations of cells. All of these parameters can play a substantial role in determining the surviving fraction of cells. Accordingly, this system, method and computer program product can assist in designing treatment plans for therapeutic radiopharmaceuticals suited to individual needs.
    Type: Application
    Filed: September 27, 2023
    Publication date: April 11, 2024
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Roger W. Howell, Sumudu Katugampola, Jianchao Wang
  • Selective ship inhibitors for treating disease
    Patent number: 11952328
    Abstract: The present disclosure provides compositions that inhibit the SH2-containing inositol 5?phosphatase (SHIP) as well as methods using such composition for use in treating or ameliorating the effects of a medical condition in a subject. For examples, compositions including the general formula as disclosed herein are suitable for use herein.
    Type: Grant
    Filed: October 17, 2019
    Date of Patent: April 9, 2024
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: William G. Kerr, John D. Chisholm
  • Systems and methods for gunshot detection
    Patent number: 11955136
    Abstract: Various embodiments of a system and associated method for detecting and localizing gunshots are disclosed herein.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: April 9, 2024
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventor: Garth Paine
  • Compositions and methods to detect gastrointestinal disease
    Patent number: 11953501
    Abstract: This invention comprises compositions and methods to determine the prognosis of necrotizing enterocolitis.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: April 9, 2024
    Assignee: BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
    Inventor: Sunyoung Kim
  • Multimetallic nanoparticles and methods of making thereof
    Patent number: 11951464
    Abstract: The present invention relates in part to a method of fabricating multimetallic nanoparticles, the method comprising the steps of providing a substrate; activating the substrate surface; adsorbing a cationic transition metal complex onto the substrate surface to form a substrate-supported cationic transition metal complex; adsorbing an anionic transition metal complex onto the substrate-supported cationic transition metal complex to form a substrate-supported multimetallic complex salt; and reducing the substrate-supported multimetallic complex salt to provide a plurality of multimetallic nanoparticles. The invention also relates in part to a composition of multimetallic nanoparticles comprising at least two metals Ma and Mb; wherein the ratio of Ma to Mb is between about 2:1 and about 1:2.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: April 9, 2024
    Assignee: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventor: Kunlun Ding
  • Apparatus and method of determining dynamic vascular parameters of blood flow
    Patent number: 11950893
    Abstract: The present disclosure relates to a method for vascular imaging and determining dynamic vascular parameters of blood flow. According to an embodiment, the present disclosure relates to an apparatus and method of determining dynamic vascular parameters of blood flow, comprising acquiring two-dimensional projection images of a vascular region of interest at a predetermined frequency, the vascular region of interest being downstream of a site of vascular administration of a radio-opaque medium, identifying, within the acquired two-dimensional projection images, heterogeneities of the radio-opaque medium, and determining the dynamic vascular parameters of the blood flow based on spatial movements of the identified heterogeneities of the radio-opaque medium. In an embodiment, the predetermined frequency is greater than 100 Hz.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: April 9, 2024
    Assignees: The Research Foundation for the State University of New York, CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Stephen Rudin, Eugene A. Mensah, Andrew Kuhls-Gilcrist
  • Rapid low-cost detection of SARS-CoV-2 using isothermal amplification and sensing methods
    Patent number: 11952637
    Abstract: Provided herein are methods and compositions for rapid, highly sensitive detection of SARS-CoV-2 in biological samples. In particular, provided herein is a rapid, low-cost method for detecting SARS-CoV-2 that provides reliable, visible test results and does not require PCR reagents, elaborate biosafety precautions, or sophisticated laboratory equipment.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: April 9, 2024
    Assignees: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY, THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
    Inventors: Alexander Green, Keith Pardee, Margot Karlikow, Kaiyue Wu, Masoud Norouzi
  • Antimicrobial thiouronium copolymers and methods of making and using the same
    Patent number: 11950593
    Abstract: Described herein are antimicrobial copolymers comprising (i) a polymer backbone and a plurality of thiouronium groups covalently bonded to the polymer backbone and (ii) a plurality of quaternary ammonium groups covalently bonded to the polymer backbone. Also described herein are methods for making the copolymers described herein and their use in disinfecting compositions.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: April 9, 2024
    Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INCORPORATED
    Inventors: Joseph Schlenoff, Sandrine Lteif
  • Selective optical aqueous and non-aqueous detection of free sulfites
    Patent number: 11953479
    Abstract: 4-pyrrolylpyridine, a novel anion sensor, displays a substantial color loss upon addition of sodium sulfite in aqueous solvents. A variety of anions were tested, including halides, phosphates, sulfates, and hydroxide, but all solutions remained unchanged aside from the sulfite, which displayed bleaching. Described here is a method for which the exact concentration of sulfites in a consumer product can be determined. The test is sensitive over a broad range of sulfites, from 0.84 ppm to over 10,000 ppm, and is accurate with a standard deviation of ±0.01 ppm.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: April 9, 2024
    Assignee: The Research Foundation for The State University of New York
    Inventors: Lynn Schmitt, Alistair Lees
  • Electronic-sensing and magnetic-modulation (ESMM) biosensor for phagocytosis quantification in pathogenic infections and methods of use thereof
    Patent number: 11951476
    Abstract: An electronic-sensing & magnetic-modulation (ESMM) biosensor device and methods of using the same, where the device incorporates electrical, microfluidic, and magnetic subsystems. The device and methods of using such a device can be applied to high throughput point-of-care screening for the quantification and evaluation of a subject's immune response to pathogenic infections, which can be useful for: early diagnosis, stratifying high-risk subjects infected with a pathogen; and determining the status or effectiveness of a therapeutic response.
    Type: Grant
    Filed: November 4, 2021
    Date of Patent: April 9, 2024
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Umer Hassan, Corey Norton
  • Urine collection, storage, and testing assembly
    Patent number: 11950769
    Abstract: A urine collection assembly includes a container; a funnel removably coupled to the container, the funnel in fluid communication with the container; a first collection chamber in selective communication with the funnel; a valve configured to allow selective communication between the first collection chamber and the funnel; a second collection chamber in selective communication with the funnel; and a lid removably coupleable to the funnel. A saddle may be removably coupleable to the funnel and configured to guide urine into the container.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: April 9, 2024
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: David Wallace, Sydney Wallace, Joshua Chang, Mark Naufel
  • Cationic platelet lysate compositions and related methods
    Patent number: 11951134
    Abstract: An acellular, anion-depleted platelet-derived peptide-rich composition comprising proteins, polypeptides and peptides <10 kDa in size, wherein the composition has anti-microbial and/or anti-inflammatory activity is disclosed. The composition can be substantially free of non-active and immunogenic factors. The composition can have a platelet-to-bacteria ratio ?1000:1. The composition can comprise plasma at a range of ?10% to ?50% plasma, optionally about 10% plasma. Methods of using the composition are also disclosed.
    Type: Grant
    Filed: September 30, 2020
    Date of Patent: April 9, 2024
    Assignees: North Carolina State University, The Trustees of the University of Pennsylvania
    Inventors: Jessica M. Gilbertie, Lauren V. Schnabel, Thomas P. Schaer